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Excitement Building Over Omnipod 5
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_
Jun 27, 2021, 1:58:26 PM6/27/21
to
The following article, optimistic views on
Omnipod 5 FDA approval and some angles
on what the Omnipod 5 consists of that I
previously had given little (if any) attention
to (article dated June 25 2021):
https://www.healthline.com/diabetesmine/omnipod-5-excitement-diabetes
[clarifying insert included in brackets,
not part of original article]
[Individuals with Islit (Insulinitis, near-total to
total loss of endogenous insulin) + individuals
with non-Islit DHGCs who use exogenous in-
sulin (estimated in 2019 to include 5.3% of
individuals with Cellosis - continued but prob-
lematic endogenous insulin no longer able ...
... to lower glucose levels < HbA1c 6.5)] can’t
wait until the first tubeless insulin pump be-
comes a “closed loop” automated system, with
the introduction of the Omnipod 5 expected by
the end of 2021.
This new system will combine the Omnipod
patch pump [tubeless insulin pump] with the
Dexcom G6 continuous glucose monitor (CGM)
and a controller algorithm to help automate in-
sulin delivery.
Notably, Omnipod 5 is set to bring mobile app
control and insulin dosing directly from your
smartphone, eliminating the need to carry a
separate Personal Diabetes Manager (PDM)
around to control the system.
Omnipod maker Insulet in Massachusetts had
experienced some delays with this product due
to the COVID-19 pandemic, but now pivotal trials
are complete and they submitted it to the Food
and Drug Administration (FDA) right around the
start of the year.
Many expect the federal agency will give it their
green light by mid-2021. As in, it could be ready
for purchase by patients by the end of the year!
What exactly is Omnipod 5?
Omnipod 5 is the latest Automated Insulin Delivery
(AID) system that combines an insulin pump and a
CGM with a controller algorithm to automatically
adjust insulin in response to predicted glucose lev-
els.
Specifically, these are referred to as hybrid closed
loop systems because they partially mimic what a
healthy pancreas does automatically — but some
user intervention is still required around food intake
and exercise.
Omnipod 5 will be the third commercially available
AID system, after Medtronic’s original 670G and the
newer Tandem Control-IQ system.
But Omnipod brings the first AID system with a no-
tubing pump.
It is a major upgrade from Insulet’s latest Omnipod
DASH platform launched in 2019 and uses the same
pods and mobile app. It will first connect with the
Dexcom CGM and later with Abbott’s FreeStyle
Libre, Insulet says.
Here are some of the key features to know about:
o It’s the same size and shape as existing Pods, worn
for up to 3 days and holding anywhere between 85
and 200 units of insulin.
o Unlike previous Omnipod versions, this new system
will eliminate the need to carry a separate PDM con-
troller device, as users can control it directly from a
smartphone app.
o At first, the mobile app will be compatible only with
certain Android smartphones, but eventually it will
work with iPhones.
o Insulet has said during investor earnings calls that
it will provide a basic phone to those who don’t have
a compatible smartphone, for use exclusively with the
Omnipod 5 app.
o The algorithm will make auto-adjustments to basal
(background) insulin rates every 5 minutes, based on
current and projected glucose values from the con-
nected CGM. It also takes into consideration insulin
on board (IOB) that’s already been dosed, and the
users recorded insulin sensitivity factors.
o It allows for varying glucose targets for different
times of day.
o Glucose targets are customizable in 10 mg/dL incre-
ments between 110 to 150 mg/dL — different than other
first-generation AID systems that have fixed targets you
can’t change.
o It includes a “HypoProtect” feature to ward off low
blood sugar that temporarily sets the target to 150
mg/dL and minimizes basal insulin delivery for exer-
cise.
o The system learns a user’s needs after the first two or
three Pods with the smart algorithm making more aggres-
sive self-adjustments based on results during the past
several days.
o It takes about 9 days for a new foundational basal pro-
gram to be set.
o You still need to bolus for food and can manually deliver
insulin corrections for higher blood sugars, but the smart
algorithm will automatically increase or decrease those
boluses based on CGM trends if glucose levels are rising
or falling.
What’s unique compared to competing commercial sys-
tems is that Omnipod 5 will be the only tubeless patch
pump system offering automation, plus the first to offer
full smartphone control including dosing capabilities from
the phone.
* * * * * * * * * * * * * * * * * * * * * * * * * * * * *
Pro-Humanist FREELOVER, I got Insulinitis
(Islit) which was caused by Insulitis at age 5
in March 1961, requiring multiple exogenous
insulin doses to try to stay alive. There are
15 specific types of rapid-onset Islit.
There is 1 specific type of slow-onset Islit,
Latent Autoimmune Islit, also unpreventable
& nonreversible (thus far).
- - -
Insulin / Insulin Pump / CGM I use
Fiasp Ultra-Fast-Acting Insulin in a
tubeless Omnipod insulin pump catheter
placed into skin / pod with adhesive
stuck onto skin every 80 hours, control
via PDM (Personal Data Manager)
https://prohuman.net/pix2/Fiaspinsulin_tubelessOmnipodDASHinsulinpump.jpg
Dexcom G6 CGM (continuous glucose monitor)
https://prohuman.net/pix2/Dexcom_G6_CGM.jpg
- - -
C.ure I.nsulinitis A.ssociation
https://prohuman.net/cureinsulinitisassociation.htm
Glucose Anomalies Research regarding
Potential Cures / Improvements in Treatments
https://prohuman.net/glucoseanomaliesresearch.htm
- - -
o Preventable Cellosis is the only specific
type of Disparate High Glucose Condition
that is preventable & reversible (in many,
sometimes it's called type 2 diabetes, often
confusingly called diabetes with no clarifier)
Risk for Preventable Cellosis, Hypertension,
& Cardiovascular Disease increases as one's
weight increases but BMI risk increases at
lower BMI levels in non-white individuals:
https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg
https://medicalxpress.com/news/2021-05-bmi-offs-obesity-diabetes-non-white.html
o PreCellosis (often confusingly called predia-
betes with no clarifier) is the oft-times preven-
table & reversible Cellosis precondition that all-
too-often the overwhelming majority having it
are unaware they have it
o 20 specific types of Cellosis, unpreventable
& nonreversible (thus far, sometimes called
type 2 diabetes, all-too-often confusingly called
diabetes with no clarifier)
Per the following article, 5.3% with Cellosis
used exogenous insulin in 2019.
https://www.bloomberg.com/press-releases/2019-12-13/tandem-diabetes-care-announces-fda-clearance-of-the-t-slim-x2-insulin-pump-with-control-iq-advanced-hybrid-closed-loop
- - -
o 4 other Disparate High Glucose Conditions
exist (Gestational Cellosis, Diminosis, Neonatal
Diminosis, Ohiglucons), all 7 DHGCs fully des-
cribed in the following article:
Logic and reasoning behind ceasing using
confusing / misleading / misinforming diabetes
& diabetic & reactive hypoglycemia words and
phrases, replacing all of that with vastly superior
clarifying names:
Diabetes Bubble / Diabetes Bubble Burst
https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
* * * * * * * * * * * * * * * * * * * * * * * * * * * * *
Omnipod 5 FDA approval and some angles
on what the Omnipod 5 consists of that I
previously had given little (if any) attention
to (article dated June 25 2021):
https://www.healthline.com/diabetesmine/omnipod-5-excitement-diabetes
[clarifying insert included in brackets,
not part of original article]
[Individuals with Islit (Insulinitis, near-total to
total loss of endogenous insulin) + individuals
with non-Islit DHGCs who use exogenous in-
sulin (estimated in 2019 to include 5.3% of
individuals with Cellosis - continued but prob-
lematic endogenous insulin no longer able ...
... to lower glucose levels < HbA1c 6.5)] can’t
wait until the first tubeless insulin pump be-
comes a “closed loop” automated system, with
the introduction of the Omnipod 5 expected by
the end of 2021.
This new system will combine the Omnipod
patch pump [tubeless insulin pump] with the
Dexcom G6 continuous glucose monitor (CGM)
and a controller algorithm to help automate in-
sulin delivery.
Notably, Omnipod 5 is set to bring mobile app
control and insulin dosing directly from your
smartphone, eliminating the need to carry a
separate Personal Diabetes Manager (PDM)
around to control the system.
Omnipod maker Insulet in Massachusetts had
experienced some delays with this product due
to the COVID-19 pandemic, but now pivotal trials
are complete and they submitted it to the Food
and Drug Administration (FDA) right around the
start of the year.
Many expect the federal agency will give it their
green light by mid-2021. As in, it could be ready
for purchase by patients by the end of the year!
What exactly is Omnipod 5?
Omnipod 5 is the latest Automated Insulin Delivery
(AID) system that combines an insulin pump and a
CGM with a controller algorithm to automatically
adjust insulin in response to predicted glucose lev-
els.
Specifically, these are referred to as hybrid closed
loop systems because they partially mimic what a
healthy pancreas does automatically — but some
user intervention is still required around food intake
and exercise.
Omnipod 5 will be the third commercially available
AID system, after Medtronic’s original 670G and the
newer Tandem Control-IQ system.
But Omnipod brings the first AID system with a no-
tubing pump.
It is a major upgrade from Insulet’s latest Omnipod
DASH platform launched in 2019 and uses the same
pods and mobile app. It will first connect with the
Dexcom CGM and later with Abbott’s FreeStyle
Libre, Insulet says.
Here are some of the key features to know about:
o It’s the same size and shape as existing Pods, worn
for up to 3 days and holding anywhere between 85
and 200 units of insulin.
o Unlike previous Omnipod versions, this new system
will eliminate the need to carry a separate PDM con-
troller device, as users can control it directly from a
smartphone app.
o At first, the mobile app will be compatible only with
certain Android smartphones, but eventually it will
work with iPhones.
o Insulet has said during investor earnings calls that
it will provide a basic phone to those who don’t have
a compatible smartphone, for use exclusively with the
Omnipod 5 app.
o The algorithm will make auto-adjustments to basal
(background) insulin rates every 5 minutes, based on
current and projected glucose values from the con-
nected CGM. It also takes into consideration insulin
on board (IOB) that’s already been dosed, and the
users recorded insulin sensitivity factors.
o It allows for varying glucose targets for different
times of day.
o Glucose targets are customizable in 10 mg/dL incre-
ments between 110 to 150 mg/dL — different than other
first-generation AID systems that have fixed targets you
can’t change.
o It includes a “HypoProtect” feature to ward off low
blood sugar that temporarily sets the target to 150
mg/dL and minimizes basal insulin delivery for exer-
cise.
o The system learns a user’s needs after the first two or
three Pods with the smart algorithm making more aggres-
sive self-adjustments based on results during the past
several days.
o It takes about 9 days for a new foundational basal pro-
gram to be set.
o You still need to bolus for food and can manually deliver
insulin corrections for higher blood sugars, but the smart
algorithm will automatically increase or decrease those
boluses based on CGM trends if glucose levels are rising
or falling.
What’s unique compared to competing commercial sys-
tems is that Omnipod 5 will be the only tubeless patch
pump system offering automation, plus the first to offer
full smartphone control including dosing capabilities from
the phone.
* * * * * * * * * * * * * * * * * * * * * * * * * * * * *
Pro-Humanist FREELOVER, I got Insulinitis
(Islit) which was caused by Insulitis at age 5
in March 1961, requiring multiple exogenous
insulin doses to try to stay alive. There are
15 specific types of rapid-onset Islit.
There is 1 specific type of slow-onset Islit,
Latent Autoimmune Islit, also unpreventable
& nonreversible (thus far).
- - -
Insulin / Insulin Pump / CGM I use
Fiasp Ultra-Fast-Acting Insulin in a
tubeless Omnipod insulin pump catheter
placed into skin / pod with adhesive
stuck onto skin every 80 hours, control
via PDM (Personal Data Manager)
https://prohuman.net/pix2/Fiaspinsulin_tubelessOmnipodDASHinsulinpump.jpg
Dexcom G6 CGM (continuous glucose monitor)
https://prohuman.net/pix2/Dexcom_G6_CGM.jpg
- - -
C.ure I.nsulinitis A.ssociation
https://prohuman.net/cureinsulinitisassociation.htm
Glucose Anomalies Research regarding
Potential Cures / Improvements in Treatments
https://prohuman.net/glucoseanomaliesresearch.htm
- - -
o Preventable Cellosis is the only specific
type of Disparate High Glucose Condition
that is preventable & reversible (in many,
sometimes it's called type 2 diabetes, often
confusingly called diabetes with no clarifier)
Risk for Preventable Cellosis, Hypertension,
& Cardiovascular Disease increases as one's
weight increases but BMI risk increases at
lower BMI levels in non-white individuals:
https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg
https://medicalxpress.com/news/2021-05-bmi-offs-obesity-diabetes-non-white.html
o PreCellosis (often confusingly called predia-
betes with no clarifier) is the oft-times preven-
table & reversible Cellosis precondition that all-
too-often the overwhelming majority having it
are unaware they have it
o 20 specific types of Cellosis, unpreventable
& nonreversible (thus far, sometimes called
type 2 diabetes, all-too-often confusingly called
diabetes with no clarifier)
Per the following article, 5.3% with Cellosis
used exogenous insulin in 2019.
https://www.bloomberg.com/press-releases/2019-12-13/tandem-diabetes-care-announces-fda-clearance-of-the-t-slim-x2-insulin-pump-with-control-iq-advanced-hybrid-closed-loop
- - -
o 4 other Disparate High Glucose Conditions
exist (Gestational Cellosis, Diminosis, Neonatal
Diminosis, Ohiglucons), all 7 DHGCs fully des-
cribed in the following article:
Logic and reasoning behind ceasing using
confusing / misleading / misinforming diabetes
& diabetic & reactive hypoglycemia words and
phrases, replacing all of that with vastly superior
clarifying names:
Diabetes Bubble / Diabetes Bubble Burst
https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
* * * * * * * * * * * * * * * * * * * * * * * * * * * * *
AntiPro&T1.1DM
Jun 27, 2021, 3:05:31 PM6/27/21
to
_ wrote:
> Glucose targets are customizable in 10 mg/dL increments between 110 to
> 150 mg/dL
My target BG is 100 mg/dl and yours is lower. So a 110 mg/dl TBG will be too
high for you.
Don't think you will be happy with that 110 mg/dl target limitation.
--
APT1.1DM = SAID+T5 = SAID+(MARD/50) = T1.1, per Lancet 5 DM Groups.
Insulinitis = Insulitis: β-cell destruction by lymphocytes, not a disease name.
Islit, cellosis and diminosis are nonsense words used by 1 crazy person on Earth.
> Glucose targets are customizable in 10 mg/dL increments between 110 to
> 150 mg/dL
My target BG is 100 mg/dl and yours is lower. So a 110 mg/dl TBG will be too
high for you.
Don't think you will be happy with that 110 mg/dl target limitation.
--
APT1.1DM = SAID+T5 = SAID+(MARD/50) = T1.1, per Lancet 5 DM Groups.
Insulinitis = Insulitis: β-cell destruction by lymphocytes, not a disease name.
Islit, cellosis and diminosis are nonsense words used by 1 crazy person on Earth.
AntiPro&T1.1DM
Jun 27, 2021, 3:30:56 PM6/27/21
to
AntiPro&T1.1DM wrote:
> So a 110 mg/dl TBG will be too high for you.
This eAG of 110 mg/dl gives a 5.5% HbA1c as a lowest possible HbA1c.
> So a 110 mg/dl TBG will be too high for you.
But your Doctor will be happy to control your hypoglycemic events.
_
Jun 27, 2021, 6:14:27 PM6/27/21
to
Follow-up:
Per a recent study of the Omnipod 5, as I
documented in the following post ...
https://groups.google.com/g/misc.health.diabetes/c/nd6zyPma6Ak/m/6cglmld6BwAJ
... the study included individuals with HbA1c
levels < 5.7, < 6, < 6.5, < 7, & > 7.
I previously made a mistake when the average
HbA1c levels being > 7, I misinterpreted that
thinking they didn't include anyone with lower
HbA1c levels. I apologize for that mistake.
Actually, they did include Islit folks that are in
the HbA1c good & great gang, HbA1c < 7,
< 6.5, < 6, & < 5.7. Until details are provided,
don't know the breakdown as to how many
had HbA1c levels that low & how many were
> 7.
My last 90 days CGM readings, average glu-
cose level 125 mg/dl, latest HbA1c = 5.4, my
time in range = 91.4%. The following chart/
article indicates why my HbA1c is lower than
what my CGM average glucose level would
indicate (note the time in range graphic ...
... which indicates the higher one's time in
range, the lower one's HbA1c level):
Clinical Targets for CGM Data Interpretation
https://www.novomedlink.com/content/dam/novonordisk/novomedlink/patient-support/product-education/insulin/docs/Clinical_Targets_For_CGM_Data-Interpretation.pdf
Also note my coefficient of variation = 32.6%,
another factor involved in HbA1c. I won't know
'til the Omnipod 5 is available, but I anticipate
that I'll be able to have HbA1c level < 5.7 with
less hypoglycemia, more time in range, less
hyperglycemia, and better sleep than I'm cur-
rently having.
On Sunday, June 27, 2021 at 12:58:26 PM UTC-5, _ wrote:
.> The following article, optimistic views on
.> Omnipod 5 FDA approval and some angles
.> on what the Omnipod 5 consists of that I
.> previously had given little (if any) attention
.> to (article dated June 25 2021):
.> https://www.healthline.com/diabetesmine/omnipod-5-excitement-diabetes
.>
.> [clarifying insert included in brackets,
.> not part of original article]
.>
.> [Individuals with Islit (Insulinitis, near-total to
.> total loss of endogenous insulin) + individuals
.> with non-Islit DHGCs who use exogenous in-
.> sulin (estimated in 2019 to include 5.3% of
.> individuals with Cellosis - continued but prob-
.> lematic endogenous insulin no longer able ...
.>
.> ... to lower glucose levels < HbA1c 6.5)] can’t
.> wait until the first tubeless insulin pump be-
.> comes a “closed loop” automated system, with
.> the introduction of the Omnipod 5 expected by
.> the end of 2021.
.>
.> This new system will combine the Omnipod
.> patch pump [tubeless insulin pump] with the
.> Dexcom G6 continuous glucose monitor (CGM)
.> and a controller algorithm to help automate in-
.> sulin delivery.
.>
.> Notably, Omnipod 5 is set to bring mobile app
.> control and insulin dosing directly from your
.> smartphone, eliminating the need to carry a
.> separate Personal Diabetes Manager (PDM)
.> around to control the system.
.>
.> Omnipod maker Insulet in Massachusetts had
.> experienced some delays with this product due
.> to the COVID-19 pandemic, but now pivotal trials
.> are complete and they submitted it to the Food
.> and Drug Administration (FDA) right around the
.> start of the year.
.>
.> Many expect the federal agency will give it their
.> green light by mid-2021. As in, it could be ready
.> for purchase by patients by the end of the year!
.>
.> What exactly is Omnipod 5?
.>
.> Omnipod 5 is the latest Automated Insulin Delivery
.> (AID) system that combines an insulin pump and a
.> CGM with a controller algorithm to automatically
.> adjust insulin in response to predicted glucose lev-
.> els.
.>
.> Specifically, these are referred to as hybrid closed
.> loop systems because they partially mimic what a
.> healthy pancreas does automatically — but some
.> user intervention is still required around food intake
.> and exercise.
.>
.> Omnipod 5 will be the third commercially available
.> AID system, after Medtronic’s original 670G and the
.> newer Tandem Control-IQ system.
.>
.> But Omnipod brings the first AID system with a no-
.> tubing pump.
.>
.> It is a major upgrade from Insulet’s latest Omnipod
.> DASH platform launched in 2019 and uses the same
.> pods and mobile app. It will first connect with the
.> Dexcom CGM and later with Abbott’s FreeStyle
.> Libre, Insulet says.
.>
.> Here are some of the key features to know about:
.>
.> o It’s the same size and shape as existing Pods, worn
.> for up to 3 days and holding anywhere between 85
.> and 200 units of insulin.
.>
.> o Unlike previous Omnipod versions, this new system
.> will eliminate the need to carry a separate PDM con-
.> troller device, as users can control it directly from a
.> smartphone app.
.>
.> o At first, the mobile app will be compatible only with
.> certain Android smartphones, but eventually it will
.> work with iPhones.
.>
.> o Insulet has said during investor earnings calls that
.> it will provide a basic phone to those who don’t have
.> a compatible smartphone, for use exclusively with the
.> Omnipod 5 app.
.>
.> o The algorithm will make auto-adjustments to basal
.> (background) insulin rates every 5 minutes, based on
.> current and projected glucose values from the con-
.> nected CGM. It also takes into consideration insulin
.> on board (IOB) that’s already been dosed, and the
.> users recorded insulin sensitivity factors.
.>
.> o It allows for varying glucose targets for different
.> times of day.
.>
.> o Glucose targets are customizable in 10 mg/dL incre-
.> ments between 110 to 150 mg/dL — different than other
.> first-generation AID systems that have fixed targets you
.> can’t change.
.>
.> o It includes a “HypoProtect” feature to ward off low
.> blood sugar that temporarily sets the target to 150
.> mg/dL and minimizes basal insulin delivery for exer-
.> cise.
.>
.> o The system learns a user’s needs after the first two or
.> three Pods with the smart algorithm making more aggres-
.> sive self-adjustments based on results during the past
.> several days.
.>
.> o It takes about 9 days for a new foundational basal pro-
.> gram to be set.
.>
.> o You still need to bolus for food and can manually deliver
.> insulin corrections for higher blood sugars, but the smart
.> algorithm will automatically increase or decrease those
.> boluses based on CGM trends if glucose levels are rising
.> or falling.
.>
.> What’s unique compared to competing commercial sys-
.> tems is that Omnipod 5 will be the only tubeless patch
.> pump system offering automation, plus the first to offer
.> full smartphone control including dosing capabilities from
.> the phone.
.>
.> * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
.>
.> Pro-Humanist FREELOVER, I got Insulinitis
.> (Islit) which was caused by Insulitis at age 5
.> in March 1961, requiring multiple exogenous
.> insulin doses to try to stay alive. There are
.> 15 specific types of rapid-onset Islit.
.>
.> There is 1 specific type of slow-onset Islit,
.> Latent Autoimmune Islit, also unpreventable
.> & nonreversible (thus far).
.>
.> - - -
.>
.> Insulin / Insulin Pump / CGM I use
.>
.> Fiasp Ultra-Fast-Acting Insulin in a
.> tubeless Omnipod insulin pump catheter
.> placed into skin / pod with adhesive
.> stuck onto skin every 80 hours, control
.> via PDM (Personal Data Manager)
.> https://prohuman.net/pix2/Fiaspinsulin_tubelessOmnipodDASHinsulinpump.jpg
.>
.> Dexcom G6 CGM (continuous glucose monitor)
.> https://prohuman.net/pix2/Dexcom_G6_CGM.jpg
.>
.> - - -
.>
.> C.ure I.nsulinitis A.ssociation
.> https://prohuman.net/cureinsulinitisassociation.htm
.>
.> Glucose Anomalies Research regarding
.> Potential Cures / Improvements in Treatments
.> https://prohuman.net/glucoseanomaliesresearch.htm
.>
.> - - -
.>
.> o Preventable Cellosis is the only specific
.> type of Disparate High Glucose Condition
.> that is preventable & reversible (in many,
.> sometimes it's called type 2 diabetes, often
.> confusingly called diabetes with no clarifier)
.>
.> Risk for Preventable Cellosis, Hypertension,
.> & Cardiovascular Disease increases as one's
.> weight increases but BMI risk increases at
.> lower BMI levels in non-white individuals:
.> https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg
.> https://medicalxpress.com/news/2021-05-bmi-offs-obesity-diabetes-non-white.html
.>
.> o PreCellosis (often confusingly called predia-
.> betes with no clarifier) is the oft-times preven-
.> table & reversible Cellosis precondition that all-
.> too-often the overwhelming majority having it
.> are unaware they have it
.>
.> o 20 specific types of Cellosis, unpreventable
.> & nonreversible (thus far, sometimes called
.> type 2 diabetes, all-too-often confusingly called
.> diabetes with no clarifier)
.>
.> https://www.bloomberg.com/press-releases/2019-12-13/tandem-diabetes-care-announces-fda-clearance-of-the-t-slim-x2-insulin-pump-with-control-iq-advanced-hybrid-closed-loop
.>
.> - - -
.>
.> o 4 other Disparate High Glucose Conditions
.> exist (Gestational Cellosis, Diminosis, Neonatal
.> Diminosis, Ohiglucons), all 7 DHGCs fully des-
.> cribed in the following article:
.>
.> Logic and reasoning behind ceasing using
.> confusing / misleading / misinforming diabetes
.> & diabetic & reactive hypoglycemia words and
.> phrases, replacing all of that with vastly superior
.> clarifying names:
.>
.> Diabetes Bubble / Diabetes Bubble Burst
.> https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
.>
.> * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
Per a recent study of the Omnipod 5, as I
documented in the following post ...
https://groups.google.com/g/misc.health.diabetes/c/nd6zyPma6Ak/m/6cglmld6BwAJ
... the study included individuals with HbA1c
levels < 5.7, < 6, < 6.5, < 7, & > 7.
I previously made a mistake when the average
HbA1c levels being > 7, I misinterpreted that
thinking they didn't include anyone with lower
HbA1c levels. I apologize for that mistake.
Actually, they did include Islit folks that are in
the HbA1c good & great gang, HbA1c < 7,
< 6.5, < 6, & < 5.7. Until details are provided,
don't know the breakdown as to how many
had HbA1c levels that low & how many were
> 7.
My last 90 days CGM readings, average glu-
cose level 125 mg/dl, latest HbA1c = 5.4, my
time in range = 91.4%. The following chart/
article indicates why my HbA1c is lower than
what my CGM average glucose level would
indicate (note the time in range graphic ...
... which indicates the higher one's time in
range, the lower one's HbA1c level):
Clinical Targets for CGM Data Interpretation
https://www.novomedlink.com/content/dam/novonordisk/novomedlink/patient-support/product-education/insulin/docs/Clinical_Targets_For_CGM_Data-Interpretation.pdf
Also note my coefficient of variation = 32.6%,
another factor involved in HbA1c. I won't know
'til the Omnipod 5 is available, but I anticipate
that I'll be able to have HbA1c level < 5.7 with
less hypoglycemia, more time in range, less
hyperglycemia, and better sleep than I'm cur-
rently having.
On Sunday, June 27, 2021 at 12:58:26 PM UTC-5, _ wrote:
.> The following article, optimistic views on
.> Omnipod 5 FDA approval and some angles
.> on what the Omnipod 5 consists of that I
.> previously had given little (if any) attention
.> to (article dated June 25 2021):
.> https://www.healthline.com/diabetesmine/omnipod-5-excitement-diabetes
.>
.> [clarifying insert included in brackets,
.> not part of original article]
.>
.> [Individuals with Islit (Insulinitis, near-total to
.> total loss of endogenous insulin) + individuals
.> with non-Islit DHGCs who use exogenous in-
.> sulin (estimated in 2019 to include 5.3% of
.> individuals with Cellosis - continued but prob-
.> lematic endogenous insulin no longer able ...
.>
.> ... to lower glucose levels < HbA1c 6.5)] can’t
.> wait until the first tubeless insulin pump be-
.> comes a “closed loop” automated system, with
.> the introduction of the Omnipod 5 expected by
.> the end of 2021.
.>
.> This new system will combine the Omnipod
.> patch pump [tubeless insulin pump] with the
.> Dexcom G6 continuous glucose monitor (CGM)
.> and a controller algorithm to help automate in-
.> sulin delivery.
.>
.> Notably, Omnipod 5 is set to bring mobile app
.> control and insulin dosing directly from your
.> smartphone, eliminating the need to carry a
.> separate Personal Diabetes Manager (PDM)
.> around to control the system.
.>
.> Omnipod maker Insulet in Massachusetts had
.> experienced some delays with this product due
.> to the COVID-19 pandemic, but now pivotal trials
.> are complete and they submitted it to the Food
.> and Drug Administration (FDA) right around the
.> start of the year.
.>
.> Many expect the federal agency will give it their
.> green light by mid-2021. As in, it could be ready
.> for purchase by patients by the end of the year!
.>
.> What exactly is Omnipod 5?
.>
.> Omnipod 5 is the latest Automated Insulin Delivery
.> (AID) system that combines an insulin pump and a
.> CGM with a controller algorithm to automatically
.> adjust insulin in response to predicted glucose lev-
.> els.
.>
.> Specifically, these are referred to as hybrid closed
.> loop systems because they partially mimic what a
.> healthy pancreas does automatically — but some
.> user intervention is still required around food intake
.> and exercise.
.>
.> Omnipod 5 will be the third commercially available
.> AID system, after Medtronic’s original 670G and the
.> newer Tandem Control-IQ system.
.>
.> But Omnipod brings the first AID system with a no-
.> tubing pump.
.>
.> It is a major upgrade from Insulet’s latest Omnipod
.> DASH platform launched in 2019 and uses the same
.> pods and mobile app. It will first connect with the
.> Dexcom CGM and later with Abbott’s FreeStyle
.> Libre, Insulet says.
.>
.> Here are some of the key features to know about:
.>
.> o It’s the same size and shape as existing Pods, worn
.> for up to 3 days and holding anywhere between 85
.> and 200 units of insulin.
.>
.> o Unlike previous Omnipod versions, this new system
.> will eliminate the need to carry a separate PDM con-
.> troller device, as users can control it directly from a
.> smartphone app.
.>
.> o At first, the mobile app will be compatible only with
.> certain Android smartphones, but eventually it will
.> work with iPhones.
.>
.> o Insulet has said during investor earnings calls that
.> it will provide a basic phone to those who don’t have
.> a compatible smartphone, for use exclusively with the
.> Omnipod 5 app.
.>
.> o The algorithm will make auto-adjustments to basal
.> (background) insulin rates every 5 minutes, based on
.> current and projected glucose values from the con-
.> nected CGM. It also takes into consideration insulin
.> on board (IOB) that’s already been dosed, and the
.> users recorded insulin sensitivity factors.
.>
.> o It allows for varying glucose targets for different
.> times of day.
.>
.> o Glucose targets are customizable in 10 mg/dL incre-
.> ments between 110 to 150 mg/dL — different than other
.> first-generation AID systems that have fixed targets you
.> can’t change.
.>
.> o It includes a “HypoProtect” feature to ward off low
.> blood sugar that temporarily sets the target to 150
.> mg/dL and minimizes basal insulin delivery for exer-
.> cise.
.>
.> o The system learns a user’s needs after the first two or
.> three Pods with the smart algorithm making more aggres-
.> sive self-adjustments based on results during the past
.> several days.
.>
.> o It takes about 9 days for a new foundational basal pro-
.> gram to be set.
.>
.> o You still need to bolus for food and can manually deliver
.> insulin corrections for higher blood sugars, but the smart
.> algorithm will automatically increase or decrease those
.> boluses based on CGM trends if glucose levels are rising
.> or falling.
.>
.> What’s unique compared to competing commercial sys-
.> tems is that Omnipod 5 will be the only tubeless patch
.> pump system offering automation, plus the first to offer
.> full smartphone control including dosing capabilities from
.> the phone.
.>
.> * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
.>
.> Pro-Humanist FREELOVER, I got Insulinitis
.> (Islit) which was caused by Insulitis at age 5
.> in March 1961, requiring multiple exogenous
.> insulin doses to try to stay alive. There are
.> 15 specific types of rapid-onset Islit.
.>
.> There is 1 specific type of slow-onset Islit,
.> Latent Autoimmune Islit, also unpreventable
.> & nonreversible (thus far).
.>
.> - - -
.>
.> Insulin / Insulin Pump / CGM I use
.>
.> Fiasp Ultra-Fast-Acting Insulin in a
.> tubeless Omnipod insulin pump catheter
.> placed into skin / pod with adhesive
.> stuck onto skin every 80 hours, control
.> via PDM (Personal Data Manager)
.> https://prohuman.net/pix2/Fiaspinsulin_tubelessOmnipodDASHinsulinpump.jpg
.>
.> Dexcom G6 CGM (continuous glucose monitor)
.> https://prohuman.net/pix2/Dexcom_G6_CGM.jpg
.>
.> - - -
.>
.> C.ure I.nsulinitis A.ssociation
.> https://prohuman.net/cureinsulinitisassociation.htm
.>
.> Glucose Anomalies Research regarding
.> Potential Cures / Improvements in Treatments
.> https://prohuman.net/glucoseanomaliesresearch.htm
.>
.> - - -
.>
.> o Preventable Cellosis is the only specific
.> type of Disparate High Glucose Condition
.> that is preventable & reversible (in many,
.> sometimes it's called type 2 diabetes, often
.> confusingly called diabetes with no clarifier)
.>
.> Risk for Preventable Cellosis, Hypertension,
.> & Cardiovascular Disease increases as one's
.> weight increases but BMI risk increases at
.> lower BMI levels in non-white individuals:
.> https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg
.> https://medicalxpress.com/news/2021-05-bmi-offs-obesity-diabetes-non-white.html
.>
.> o PreCellosis (often confusingly called predia-
.> betes with no clarifier) is the oft-times preven-
.> table & reversible Cellosis precondition that all-
.> too-often the overwhelming majority having it
.> are unaware they have it
.>
.> o 20 specific types of Cellosis, unpreventable
.> & nonreversible (thus far, sometimes called
.> type 2 diabetes, all-too-often confusingly called
.> diabetes with no clarifier)
.>
> Per the following article, 5.3% with Cellosis
.> used exogenous insulin in 2019.
.> https://www.bloomberg.com/press-releases/2019-12-13/tandem-diabetes-care-announces-fda-clearance-of-the-t-slim-x2-insulin-pump-with-control-iq-advanced-hybrid-closed-loop
.>
.> - - -
.>
.> o 4 other Disparate High Glucose Conditions
.> exist (Gestational Cellosis, Diminosis, Neonatal
.> Diminosis, Ohiglucons), all 7 DHGCs fully des-
.> cribed in the following article:
.>
.> Logic and reasoning behind ceasing using
.> confusing / misleading / misinforming diabetes
.> & diabetic & reactive hypoglycemia words and
.> phrases, replacing all of that with vastly superior
.> clarifying names:
.>
.> Diabetes Bubble / Diabetes Bubble Burst
.> https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
.>
.> * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
AntiPro&T1.1DM
Jun 28, 2021, 11:17:30 AM6/28/21
to
_ wrote:
> I anticipate that I'll be able to have HbA1c level < 5.7
If the control program limits your Target BG to 110 mg/dl, then your HbA1c
> I anticipate that I'll be able to have HbA1c level < 5.7
will be higher then you currently have now. I've asked you for your current
Target BG in the past. But you never answered the question. My guess is
your current Target BG is 80 mg/dl. The difference in HbA1c from 80 mg/dl
to 110 mg/dl is 1% change in HbA1c. So I expect your HbA1c to be 6.4%
when you start the closed-loop insulin pump system.
You may have to hack into the pump control software to change the Target BG.
Suspect you could put the software into debug mode and then write into the
memory location that holds the Target BG to lower it below 110 mg/dl. Not
sure how the manufacturer could protect itself from a lawsuit if you have
another car accident from hypoglycemia while using the closed-loop system.
My current Target BG is 100 mg/dl giving a 5.1% lowest possible HbA1c. Since
I wrote the software for my control program, I can change any parameter. I've
been thinking about moving my Target BG to 90 mg/dl. I used to use that set
point before I had nocturnal hypoglycemic seizures. Since I no longer have
these seizures, (stopped using Humalog/Lispro), my Dawn Phenomenon is
back to normal and I could risk a lower Target BG now. The 90 mg/dl HbA1c
would have a 4.8% lowest possible value.
Just changed it in my insulin dosing control software. TBG = 90 mg/dl now.
_
Jun 28, 2021, 12:18:00 PM6/28/21
to
APT says
.> _ wrote a lot, see following link, 1 part
.> of that displayed below:
https://groups.google.com/g/misc.health.diabetes/c/VROQh77bAjo/m/uV95SDiKBwAJ
.>
.> > I anticipate that I'll be able to have HbA1c level < 5.7 ...
> If the control program limits your Target BG to 110 mg/dl, ...
The Omnipod 5 program that says it
will auto-adjust basal with a CGM goal
of 110 mg/dl, no way to know what an
individual's actual average CGM will
be (as stated, mine is currently 125
mg/dl for last 90 days) -or- what their
'time in range' will be (the latest study ...
... shows improvement on average but
their time in range average & HbA1c
average is much higher than mine),
my time in range is 91.4% over last 90
days & HbA1c 5.4 in most recent test.
My hope that I'll improve & get more
sleep with the Omnipod 5, having less
happen 'til I actually use the device.
Keep in mind the Omnipod 5 allows
bolus adjustments & requires manual
bolus to deal with food intake, so that
will work like it does now but with auto-
basal adjustments to counter both hypo
& hyper states.
The data in the January study (not the
recent study) showed CGM average glu-
cose much higher than the CGM goal,
and hyperglycemia% much higher than
what I currently have. Hypoglycemia%,
lower than what I currently have.
https://www.liebertpub.com/na101/home/literatum/publisher/mal/journals/content/dia/2021/dia.2021.23.issue-6/dia.2020.0546/20210602/images/medium/dia.2020.0546_inline1.jpg
Rest assured that I'll do whatever it takes
to keep my time in range > 90% & my aver-
age glucose level < 125 mg/dl, but cannot
know 'til I know -if- the Omnipod 5 improves
my current levels with more sleep, or not.
Am I being overly ambitious regarding the ...
... possibilities of better Islit management
with a closed-loop Omnipod 5? I won't
know 'til I get one & rest assured, I'll re-
port back on how well the Omnipod 5 does
(& how happy I am) or how poorly it does
(& how disappointed I am) based on the ...
... manner in which the Omnipod 5 impacts
my glucose levels & ability to get good sleep
without having to wake up & check on my
glucose levels.
* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
* Diabetes Bubble / Diabetes Bubble Burst
* https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
*
* C.ure I.nsulinitis A.ssociation
* https://prohuman.net/cureinsulinitisassociation.htm
*
* Glucose Anomalies Research regarding
* Potential Cures / Improvements in Treatments
* https://prohuman.net/glucoseanomaliesresearch.htm
* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
.> _ wrote a lot, see following link, 1 part
.> of that displayed below:
https://groups.google.com/g/misc.health.diabetes/c/VROQh77bAjo/m/uV95SDiKBwAJ
.>
.> > I anticipate that I'll be able to have HbA1c level < 5.7 ...
> If the control program limits your Target BG to 110 mg/dl, ...
The Omnipod 5 program that says it
will auto-adjust basal with a CGM goal
of 110 mg/dl, no way to know what an
individual's actual average CGM will
be (as stated, mine is currently 125
mg/dl for last 90 days) -or- what their
'time in range' will be (the latest study ...
... shows improvement on average but
their time in range average & HbA1c
average is much higher than mine),
my time in range is 91.4% over last 90
days & HbA1c 5.4 in most recent test.
My hope that I'll improve & get more
sleep with the Omnipod 5, having less
hypoglycemia, more time in range, less
hyperglycemia, won't know if that will
happen 'til I actually use the device.
Keep in mind the Omnipod 5 allows
bolus adjustments & requires manual
bolus to deal with food intake, so that
will work like it does now but with auto-
basal adjustments to counter both hypo
& hyper states.
The data in the January study (not the
recent study) showed CGM average glu-
cose much higher than the CGM goal,
and hyperglycemia% much higher than
what I currently have. Hypoglycemia%,
lower than what I currently have.
https://www.liebertpub.com/na101/home/literatum/publisher/mal/journals/content/dia/2021/dia.2021.23.issue-6/dia.2020.0546/20210602/images/medium/dia.2020.0546_inline1.jpg
Rest assured that I'll do whatever it takes
to keep my time in range > 90% & my aver-
age glucose level < 125 mg/dl, but cannot
know 'til I know -if- the Omnipod 5 improves
my current levels with more sleep, or not.
Am I being overly ambitious regarding the ...
... possibilities of better Islit management
with a closed-loop Omnipod 5? I won't
know 'til I get one & rest assured, I'll re-
port back on how well the Omnipod 5 does
(& how happy I am) or how poorly it does
(& how disappointed I am) based on the ...
... manner in which the Omnipod 5 impacts
my glucose levels & ability to get good sleep
without having to wake up & check on my
glucose levels.
* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
* Diabetes Bubble / Diabetes Bubble Burst
* https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
*
* C.ure I.nsulinitis A.ssociation
* https://prohuman.net/cureinsulinitisassociation.htm
*
* Glucose Anomalies Research regarding
* Potential Cures / Improvements in Treatments
* https://prohuman.net/glucoseanomaliesresearch.htm
* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
AntiPro&T1.1DM
Jun 28, 2021, 12:32:04 PM6/28/21
to
_ wrote:
> Omnipod 5 allows bolus adjustments
So you'll bolus to correct hyperglycemia and the pump will turn off your
> Omnipod 5 allows bolus adjustments
basal insulin to prevent hypoglycemia. I predict your HbA1c will be higher
and you'll be fighting the closed-loop system to get your HbA1c lower.
So you should be happy if your HbA1c is <= 6.5%. Perfect for a T1D.
_
Jun 28, 2021, 1:48:27 PM6/28/21
to
On Monday, June 28, 2021 at 11:32:04 AM UTC-5, AntiPro&T1.1DM wrote:
> _ wrote a lot, see following link, part
> of that, a tiny part, included below:
https://groups.google.com/g/misc.health.diabetes/c/VROQh77bAjo/m/He2uroKLAAAJ
> > ... Omnipod 5 allows bolus adjustments ...
> So you'll bolus to correct hyperglycemia and the pump will turn off your
> basal insulin to prevent hypoglycemia. I predict your HbA1c will be higher
> and you'll be fighting the closed-loop system to get your HbA1c lower.
Ideally, bolus + auto-basal adjustments will
allow me to avoid all hyperglycemia, but since
I don't have a fully functional pancreas, & guess-
ing required in all bolus dosages, that's unlikely.
I predict you're under-estimating my ability to
use the Omnipod 5 and you're under-estimat-
ing my ability to lower hypoglycemia, increase
time in range, lower hyperglycemia, & increase
good sleep by using the Omnipod 5.
Your position, anti-CGM, anti-insulin-pumps,
anti-Omnipod 5 closed loop tubeless insulin
pump, instead advocating your using a secret
formula with insulin injections & mysterious
glucose-tests with bloodpricks, not knowing
what your glucose levels are for all-but a few ...
...minutes every 24 hours (over 99% not know-
ing).
I have confidence in my ability to succeed using
the Omnipod 5, improving my great Islit manage-
ment success, but I wont know for sure 'til I get
the Omnipod 5 late in 2021 or early in 2022, along
with likely getting the Dexcom G7 or the Freestyle
Libre 3 (if approved for use with Omnipod 5) ...
... simultaneous to or before getting the Omnipod 5,
presuming all 3 devices are FDA approved in the
U.S. and available by then.
p.s. Also found out I'm about to enter the high cost
'donut hole'. I will come close to having enough
Omnipods for the rest of 2021, & will have enough
insulin for the rest of 2021, so the only device I'll
have to purchase in the 'donut hole', its classifica-
tion as non-pharmacy medical equipment may ...
... allow me to avoid paying more for it (Dexcom G6
sensors & transmitters).
Insulin, depends on if the time we lost power will
adversely impact the insulin that wasn't refrigerated
during the deadly life-risking Texas power outage. It
hasn't thus far.
~* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
~* Diabetes Bubble / Diabetes Bubble Burst
~* https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
~*
~* C.ure I.nsulinitis A.ssociation
~* https://prohuman.net/cureinsulinitisassociation.htm
~*
~* Glucose Anomalies Research regarding
~* Potential Cures / Improvements in Treatments
~* https://prohuman.net/glucoseanomaliesresearch.htm
~* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
> _ wrote a lot, see following link, part
> of that, a tiny part, included below:
https://groups.google.com/g/misc.health.diabetes/c/VROQh77bAjo/m/He2uroKLAAAJ
> > ... Omnipod 5 allows bolus adjustments ...
> So you'll bolus to correct hyperglycemia and the pump will turn off your
> basal insulin to prevent hypoglycemia. I predict your HbA1c will be higher
> and you'll be fighting the closed-loop system to get your HbA1c lower.
allow me to avoid all hyperglycemia, but since
I don't have a fully functional pancreas, & guess-
ing required in all bolus dosages, that's unlikely.
I predict you're under-estimating my ability to
use the Omnipod 5 and you're under-estimat-
ing my ability to lower hypoglycemia, increase
time in range, lower hyperglycemia, & increase
good sleep by using the Omnipod 5.
Your position, anti-CGM, anti-insulin-pumps,
anti-Omnipod 5 closed loop tubeless insulin
pump, instead advocating your using a secret
formula with insulin injections & mysterious
glucose-tests with bloodpricks, not knowing
what your glucose levels are for all-but a few ...
...minutes every 24 hours (over 99% not know-
ing).
I have confidence in my ability to succeed using
the Omnipod 5, improving my great Islit manage-
ment success, but I wont know for sure 'til I get
the Omnipod 5 late in 2021 or early in 2022, along
with likely getting the Dexcom G7 or the Freestyle
Libre 3 (if approved for use with Omnipod 5) ...
... simultaneous to or before getting the Omnipod 5,
presuming all 3 devices are FDA approved in the
U.S. and available by then.
p.s. Also found out I'm about to enter the high cost
'donut hole'. I will come close to having enough
Omnipods for the rest of 2021, & will have enough
insulin for the rest of 2021, so the only device I'll
have to purchase in the 'donut hole', its classifica-
tion as non-pharmacy medical equipment may ...
... allow me to avoid paying more for it (Dexcom G6
sensors & transmitters).
Insulin, depends on if the time we lost power will
adversely impact the insulin that wasn't refrigerated
during the deadly life-risking Texas power outage. It
hasn't thus far.
~* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
~* Diabetes Bubble / Diabetes Bubble Burst
~* https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
~*
~* C.ure I.nsulinitis A.ssociation
~* https://prohuman.net/cureinsulinitisassociation.htm
~*
~* Glucose Anomalies Research regarding
~* Potential Cures / Improvements in Treatments
~* https://prohuman.net/glucoseanomaliesresearch.htm
~* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
AntiPro&T1.1DM
Jun 28, 2021, 3:12:23 PM6/28/21
to
_ wrote:
> improving my great diabetes management success
If this were true, you wouldn't be bitching about diabetes CONTROL being
unpredictable. So you are NOT SUCCESSFUL in diabetes management.
If anything, I'm over-estimating your intelligence. So I expect failure from
you.
The World will be a safer place with your HbA1c higher using the OP5 system.
> improving my great diabetes management success
If this were true, you wouldn't be bitching about diabetes CONTROL being
unpredictable. So you are NOT SUCCESSFUL in diabetes management.
If anything, I'm over-estimating your intelligence. So I expect failure from
you.
The World will be a safer place with your HbA1c higher using the OP5 system.
_
Jun 28, 2021, 4:29:42 PM6/28/21
to
APT says:
> _ wrote a lot, see following link for details,
> the replier including part of one sentence,
> shown below:
https://groups.google.com/g/misc.health.diabetes/c/VROQh77bAjo/m/HpTPPHKQAAAJ
> > ... improving my great Islit management success ...
My success, HbA1c steadily under 5.7 since
2013, time in range above 90%.
[clarifying inserts, not part of APT's reply,
included in brackets to improve accuracy,
clarity, verity]
> If this were true, you wouldn't be [saying anything]
> ... about [the 1 DHGC I've had over 60 years exper-
> ience dealing with, Islit] CONTROL being unpredic-
> table.
You've ignored all evidence about the verity of
that statement including all statements validat-
ing that position from other Islit individuals.
-If- Islit was totally predictable, as if Islit indivi-
duals had a fully functional pancreas, problem
solved, but Islit individuals DON'T HAVE A
FULLY FUNCTIONAL PANCREAS, and DON'T
have any way to accurately predict all endo-
genous activity impacting glucose levels, and ...
... DON'T have a way to accurately predict
what happens when sleeping, and DON'T
have a way to accurately predict/deal with
glucose variation from food/drink/exogenous
insulin basal & bolus dosages.
-If- Islit was totally predictable, NO ISLIT indi-
viduals would have ANY hypoglycemia and
NO ISLIT individuals would have ANY hyper-
glycemia.
Problem is, without a fully functional pancreas,
manual management of glucose levels entail-
ing all the unpredictability factors detailed above
and more are currently required with current state
of the art technology. Hopefully, Omnipod 5 will
improve on that, won't know 'til I get one.
Two examples of unpredictability in direct quotes
in links to comments from Islit individuals in pre-
vious posts:
September 13 2019
https://groups.google.com/g/misc.health.diabetes/c/TvCc9Fn5GR8/m/x7kMDSQnBQAJ
In an article about Hannah Giffin's
Insulinitis (Islit), near-total to total
loss of endogenous insulin, the fol-
lowing quote speaks to the death
of Marie Orechoff at age 27:
https://www.mpacorn.com/articles/moorpark-native-aims-to-strike-out-type-1-diabetes-with-bowling-fundraiser/
Quote [with clarifying insert, not
part of original quote, included
in brackets]:
"This year’s Bowling for a Cure,
set for Sat., Sept. 14 at Harley’s
Bowl in Simi Valley, will be dedi-
cated to the memory of Marie Ore-
choff.
Orechoff, a 27-year-old Moorpark
native, lost her life this summer
to Type 1 diabetes [Islit].
“She did nothing wrong. She was
living her life and managing her
disease, but this disease is
unpredictable
and no matter how hard we try,
things happen that are outside of
our control,” Giffin said. “This
could happen to anyone. Stories
like Marie’s rarely get shared,
but this is our reality.”
~~~
June 24 2021
https://groups.google.com/g/misc.health.diabetes/c/T3kLnEXiYkE/m/8NZkskCfBgAJ
https://www.wbir.com/article/news/local/five-at-four/teenage-crossfit-athlete-battles-type-1-diabetes-inspires-others/51-11be50be-5543-4b99-80af-0916d666ac39
Delaney Wade ... agrees with my perspective on
Islit unpredictability as indicated in the following
quote / excerpt:
"... It's a roller coaster, to be honest. My sugars,
they'll be low, high, good, and it can be up and
down, but it's not like a bad roller coaster," Wade
said. "You just can't really predict it. It's really not
predictable." ...
/~* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
/~* Diabetes Bubble / Diabetes Bubble Burst
/~* https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
/~*
/~* C.ure I.nsulinitis A.ssociation
/~* https://prohuman.net/cureinsulinitisassociation.htm
/~*
/~* Glucose Anomalies Research regarding
/~* Potential Cures / Improvements in Treatments
/~* https://prohuman.net/glucoseanomaliesresearch.htm
/~* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
> _ wrote a lot, see following link for details,
> the replier including part of one sentence,
> shown below:
https://groups.google.com/g/misc.health.diabetes/c/VROQh77bAjo/m/HpTPPHKQAAAJ
> > ... improving my great Islit management success ...
My success, HbA1c steadily under 5.7 since
2013, time in range above 90%.
[clarifying inserts, not part of APT's reply,
included in brackets to improve accuracy,
clarity, verity]
> If this were true, you wouldn't be [saying anything]
> ... about [the 1 DHGC I've had over 60 years exper-
> ience dealing with, Islit] CONTROL being unpredic-
> table.
You've ignored all evidence about the verity of
that statement including all statements validat-
ing that position from other Islit individuals.
-If- Islit was totally predictable, as if Islit indivi-
duals had a fully functional pancreas, problem
solved, but Islit individuals DON'T HAVE A
FULLY FUNCTIONAL PANCREAS, and DON'T
have any way to accurately predict all endo-
genous activity impacting glucose levels, and ...
... DON'T have a way to accurately predict
what happens when sleeping, and DON'T
have a way to accurately predict/deal with
glucose variation from food/drink/exogenous
insulin basal & bolus dosages.
-If- Islit was totally predictable, NO ISLIT indi-
viduals would have ANY hypoglycemia and
NO ISLIT individuals would have ANY hyper-
glycemia.
Problem is, without a fully functional pancreas,
manual management of glucose levels entail-
ing all the unpredictability factors detailed above
and more are currently required with current state
of the art technology. Hopefully, Omnipod 5 will
improve on that, won't know 'til I get one.
Two examples of unpredictability in direct quotes
in links to comments from Islit individuals in pre-
vious posts:
September 13 2019
https://groups.google.com/g/misc.health.diabetes/c/TvCc9Fn5GR8/m/x7kMDSQnBQAJ
In an article about Hannah Giffin's
Insulinitis (Islit), near-total to total
loss of endogenous insulin, the fol-
lowing quote speaks to the death
of Marie Orechoff at age 27:
https://www.mpacorn.com/articles/moorpark-native-aims-to-strike-out-type-1-diabetes-with-bowling-fundraiser/
Quote [with clarifying insert, not
part of original quote, included
in brackets]:
"This year’s Bowling for a Cure,
set for Sat., Sept. 14 at Harley’s
Bowl in Simi Valley, will be dedi-
cated to the memory of Marie Ore-
choff.
Orechoff, a 27-year-old Moorpark
native, lost her life this summer
to Type 1 diabetes [Islit].
“She did nothing wrong. She was
living her life and managing her
disease, but this disease is
unpredictable
and no matter how hard we try,
things happen that are outside of
our control,” Giffin said. “This
could happen to anyone. Stories
like Marie’s rarely get shared,
but this is our reality.”
~~~
June 24 2021
https://groups.google.com/g/misc.health.diabetes/c/T3kLnEXiYkE/m/8NZkskCfBgAJ
https://www.wbir.com/article/news/local/five-at-four/teenage-crossfit-athlete-battles-type-1-diabetes-inspires-others/51-11be50be-5543-4b99-80af-0916d666ac39
Delaney Wade ... agrees with my perspective on
Islit unpredictability as indicated in the following
quote / excerpt:
"... It's a roller coaster, to be honest. My sugars,
they'll be low, high, good, and it can be up and
down, but it's not like a bad roller coaster," Wade
said. "You just can't really predict it. It's really not
predictable." ...
/~* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
/~* Diabetes Bubble / Diabetes Bubble Burst
/~* https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
/~*
/~* C.ure I.nsulinitis A.ssociation
/~* https://prohuman.net/cureinsulinitisassociation.htm
/~*
/~* Glucose Anomalies Research regarding
/~* Potential Cures / Improvements in Treatments
/~* https://prohuman.net/glucoseanomaliesresearch.htm
/~* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
AntiPro&T1.1DM
Jun 28, 2021, 5:19:56 PM6/28/21
to
_ wrote:
> things happen that are outside of our control
That's called life. You learn to work with these imperfections by not
> things happen that are outside of our control
overdosing insulin. Then check BG after the dose is finished in 4 hours.
But you should never expect exact performance. So you give a wide buffer
for hormonal changes in your body.
When you're using the OP5 system, the World will have less car accidents.
So I can't wait for your CONTROL to improve when using the OP5 system.
_
Jul 12, 2021, 1:10:19 PM7/12/21
to
Follow-up regarding Delaney Wade's Islit
diagnosis in 2019:
On Monday, June 28, 2021 at 3:29:42 PM UTC-5, _ wrote:
~> > _ wrote a lot, see following link for details,
~> > the replier including part of one sentence,
~> > shown below:
~> https://groups.google.com/g/misc.health.diabetes/c/VROQh77bAjo/m/HpTPPHKQAAAJ
~>
~> > > ... improving my great Islit management success ...
~>
~> My success, HbA1c steadily under 5.7 since
~> 2013, time in range above 90%.
~>
~> ...
~>
~> -If- Islit was totally predictable, as if Islit indivi-
~> duals had a fully functional pancreas, problem
~> solved, but Islit individuals DON'T HAVE A
~> FULLY FUNCTIONAL PANCREAS, and DON'T
~> have any way to accurately predict all endo-
~> genous activity impacting glucose levels, and ...
~>
~> ... DON'T have a way to accurately predict
~> what happens when sleeping, and DON'T
~> have a way to accurately predict/deal with
~> glucose variation from food/drink/exogenous
~> insulin basal & bolus dosages.
~>
~> -If- Islit was totally predictable, NO ISLIT indi-
~> viduals would have ANY hypoglycemia and
~> NO ISLIT individuals would have ANY hyper-
~> glycemia.
~>
~> Problem is, without a fully functional pancreas,
~> manual management of glucose levels entail-
~> ing all the unpredictability factors detailed above
~> and more are currently required with current state
~> of the art technology. Hopefully, Omnipod 5 will
~> improve on that, won't know 'til I get one.
~>
~> Two examples of unpredictability in direct quotes
~> in links to comments from Islit individuals in pre-
~> vious posts:
~>
~> September 13 2019
~> https://groups.google.com/g/misc.health.diabetes/c/TvCc9Fn5GR8/m/x7kMDSQnBQAJ
~>
~> In an article about Hannah Giffin's
~> Insulinitis (Islit), near-total to total
~> loss of endogenous insulin, the fol-
~> lowing quote speaks to the death
~> of Marie Orechoff at age 27:
~> https://www.mpacorn.com/articles/moorpark-native-aims-to-strike-out-type-1-diabetes-with-bowling-fundraiser/
~>
~> Quote [with clarifying insert, not
~> part of original quote, included
~> in brackets]:
~>
~> "This year’s Bowling for a Cure,
~> set for Sat., Sept. 14 at Harley’s
~> Bowl in Simi Valley, will be dedi-
~> cated to the memory of Marie Ore-
~> choff.
~>
~> Orechoff, a 27-year-old Moorpark
~> native, lost her life this summer
~> to Type 1 diabetes [Islit].
~>
~> “She did nothing wrong. She was
~> living her life and managing her
~> disease, but this disease is
~>
~> unpredictable
~>
~> and no matter how hard we try,
~> things happen that are outside of
~> our control,” Giffin said. “This
~> could happen to anyone. Stories
~> like Marie’s rarely get shared,
~> but this is our reality.”
~>
~> ~~~
~>
~> June 24 2021
~> https://groups.google.com/g/misc.health.diabetes/c/T3kLnEXiYkE/m/8NZkskCfBgAJ
~>
~> https://www.wbir.com/article/news/local/five-at-four/teenage-crossfit-athlete-battles-type-1-diabetes-inspires-others/51-11be50be-5543-4b99-80af-0916d666ac39
~>
~> Delaney Wade ... agrees with my perspective on
~> Islit unpredictability as indicated in the following
~> quote / excerpt:
~>
~> "... It's a roller coaster, to be honest. My sugars,
~> they'll be low, high, good, and it can be up and
~> down, but it's not like a bad roller coaster," Wade
~> said. "You just can't really predict it. It's really not
~> predictable." ...
- - -
July 11 2021
Putting in the Work: 15-Year-Old
Delaney Wade Manages Islit
https://morningchalkup.com/2021/07/11/putting-in-the-work-15-year-old-delaney-wade-manages-type-1-diabetes-qualifies-for-the-crossfit-games-teen-division/
- - -
... In 2019, Wade finally went to the doctors and
was diagnosed with Type 1 Diabetes [Islit]. That
day, her blood sugar levels were in the high 600s,
which, according to her doctor, should have landed
her in the ICU.
... “It’s a rollercoaster,” adds Bruce (Delaney's dad).
“Trying to pattern it and track it, and we’ve done well
considering, but trying to understand what causes
highs, what causes lows… we know carbs cause
highs, but if you’re lifting heavy, at a slower pace, ...
... then you tend to go up. If you are doing a lot more
cardio, fast-paced stuff, it tends to fall.”
~~~
Another recent post with extensive elaboration
about Islit unpredictability, from Courtney Pitson,
who's had Islit since age 2, for the last 21 years:
https://groups.google.com/g/misc.health.diabetes/c/rrCAgX5qr04/m/X54QFB2bAQAJ
... “There’s a projected idea that being [an Islit indivi-
dual] is okay, that it’s not that hard, but it’s actually
really hard. I wish that people knew how hard it is
and how it really does change your life forever.”
diagnosis in 2019:
On Monday, June 28, 2021 at 3:29:42 PM UTC-5, _ wrote:
~> > _ wrote a lot, see following link for details,
~> > the replier including part of one sentence,
~> > shown below:
~> https://groups.google.com/g/misc.health.diabetes/c/VROQh77bAjo/m/HpTPPHKQAAAJ
~>
~> > > ... improving my great Islit management success ...
~>
~> My success, HbA1c steadily under 5.7 since
~> 2013, time in range above 90%.
~>
~> ...
~>
~> -If- Islit was totally predictable, as if Islit indivi-
~> duals had a fully functional pancreas, problem
~> solved, but Islit individuals DON'T HAVE A
~> FULLY FUNCTIONAL PANCREAS, and DON'T
~> have any way to accurately predict all endo-
~> genous activity impacting glucose levels, and ...
~>
~> ... DON'T have a way to accurately predict
~> what happens when sleeping, and DON'T
~> have a way to accurately predict/deal with
~> glucose variation from food/drink/exogenous
~> insulin basal & bolus dosages.
~>
~> -If- Islit was totally predictable, NO ISLIT indi-
~> viduals would have ANY hypoglycemia and
~> NO ISLIT individuals would have ANY hyper-
~> glycemia.
~>
~> Problem is, without a fully functional pancreas,
~> manual management of glucose levels entail-
~> ing all the unpredictability factors detailed above
~> and more are currently required with current state
~> of the art technology. Hopefully, Omnipod 5 will
~> improve on that, won't know 'til I get one.
~>
~> Two examples of unpredictability in direct quotes
~> in links to comments from Islit individuals in pre-
~> vious posts:
~>
~> September 13 2019
~> https://groups.google.com/g/misc.health.diabetes/c/TvCc9Fn5GR8/m/x7kMDSQnBQAJ
~>
~> In an article about Hannah Giffin's
~> Insulinitis (Islit), near-total to total
~> loss of endogenous insulin, the fol-
~> lowing quote speaks to the death
~> of Marie Orechoff at age 27:
~> https://www.mpacorn.com/articles/moorpark-native-aims-to-strike-out-type-1-diabetes-with-bowling-fundraiser/
~>
~> Quote [with clarifying insert, not
~> part of original quote, included
~> in brackets]:
~>
~> "This year’s Bowling for a Cure,
~> set for Sat., Sept. 14 at Harley’s
~> Bowl in Simi Valley, will be dedi-
~> cated to the memory of Marie Ore-
~> choff.
~>
~> Orechoff, a 27-year-old Moorpark
~> native, lost her life this summer
~> to Type 1 diabetes [Islit].
~>
~> “She did nothing wrong. She was
~> living her life and managing her
~> disease, but this disease is
~>
~> unpredictable
~>
~> and no matter how hard we try,
~> things happen that are outside of
~> our control,” Giffin said. “This
~> could happen to anyone. Stories
~> like Marie’s rarely get shared,
~> but this is our reality.”
~>
~> ~~~
~>
~> June 24 2021
~> https://groups.google.com/g/misc.health.diabetes/c/T3kLnEXiYkE/m/8NZkskCfBgAJ
~>
~> https://www.wbir.com/article/news/local/five-at-four/teenage-crossfit-athlete-battles-type-1-diabetes-inspires-others/51-11be50be-5543-4b99-80af-0916d666ac39
~>
~> Delaney Wade ... agrees with my perspective on
~> Islit unpredictability as indicated in the following
~> quote / excerpt:
~>
~> "... It's a roller coaster, to be honest. My sugars,
~> they'll be low, high, good, and it can be up and
~> down, but it's not like a bad roller coaster," Wade
~> said. "You just can't really predict it. It's really not
~> predictable." ...
- - -
July 11 2021
Putting in the Work: 15-Year-Old
Delaney Wade Manages Islit
https://morningchalkup.com/2021/07/11/putting-in-the-work-15-year-old-delaney-wade-manages-type-1-diabetes-qualifies-for-the-crossfit-games-teen-division/
- - -
... In 2019, Wade finally went to the doctors and
was diagnosed with Type 1 Diabetes [Islit]. That
day, her blood sugar levels were in the high 600s,
which, according to her doctor, should have landed
her in the ICU.
... “It’s a rollercoaster,” adds Bruce (Delaney's dad).
“Trying to pattern it and track it, and we’ve done well
considering, but trying to understand what causes
highs, what causes lows… we know carbs cause
highs, but if you’re lifting heavy, at a slower pace, ...
... then you tend to go up. If you are doing a lot more
cardio, fast-paced stuff, it tends to fall.”
~~~
Another recent post with extensive elaboration
about Islit unpredictability, from Courtney Pitson,
who's had Islit since age 2, for the last 21 years:
https://groups.google.com/g/misc.health.diabetes/c/rrCAgX5qr04/m/X54QFB2bAQAJ
... “There’s a projected idea that being [an Islit indivi-
dual] is okay, that it’s not that hard, but it’s actually
really hard. I wish that people knew how hard it is
and how it really does change your life forever.”
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