Google Groups no longer supports new Usenet posts or subscriptions. Historical content remains viewable.
Dismiss
FUN stuff --> Longevinex - (10) Mercola - Byron -Ai-> Diabetes - JBS look back -->JW (The Duke) --Charles Murray-->Imprimis --Jobs down the Whirlpool? --Hire Chinese? -- Mucin & Cancer --VSL#3 - Cogan -INQ -> Pagano -TIME -Higgs Boson
14 views
Skip to first unread message
randall
Feb 8, 2012, 1:53:45 PM2/8/12
to
hi
randumb thoughts of time and universe and skin.
OK this is first and foremost today:
http://www.ncbi.nlm.nih.gov/pubmed/22039501
Identification and characterisation of an iron-responsive candidate
probiotic.
[...] PMID: 22039501
so i save the BEST for LAST... or next to it or next to that.
And if i forget watch this carbon youtube... it's xlnt
carbon: modern marvels
http://www.youtube.com/watch?v=cfPjeMotfR8
<time 44:44> <views: 33,950>
But i already posted it twice but the post to Julie isn't coming up?
Yes it just did... so there...
Oh well... maybe the new google policy isn't working right?
Hey? I'll do a post on that?
OK...
-----------
Kewl action packed PURE ADRENALIN, youtube:
http://www.youtube.com/v/EEu42L0ufBY%26rel%3d0%26hl%3den_US%26feature%3dplayer_embedded%26version%3d3
It makes me think of that pig on the zip line...
Maxwell the Pig Returns! Zip-line Piggy - New GEICO Commercial
http://www.youtube.com/watch?v=6TlNOwwQQJk
First maxwell went wee wee wee all the way home and now he's zip
lining it..
He's an adrenalin junky for sure..
So are the guys on that kewl action packed youtube..<G>
==============
And before i do another THING:
One of the minor reasons i use longevinex.com resveratrol.
http://www.longevinex.com/articles/resveratrol-pill-manufacturer-posts-its-science-for-public-professional-examination/
Keeps your heart going?
But i like keeping crap outa my cells... stat to the eR (endoplasmic
reticulum)
25 hits: endoplasmic reticulum resveratrol-- pubmed
http://www.ncbi.nlm.nih.gov/pubmed?term=endoplasmic%20reticulum%20resveratrol
I can only wonder what happened when 122 year old Jeanne Calment drank
her glass of red wine PORT and consumed chocolates (one kilo a week)
and EVOO each day.
Was it the olive oil or chocolate or red wine that kept those ER's
going stat?
=============
mercola - non homeostatic iodine
http://articles.mercola.com/sites/articles/archive/2012/02/08/iodine-is-important-but-new-study-shows-too-much-causes-problems.aspx
Story at-a-glance
While there is evidence iodine levels are decreasing in the United
States, you need to be very careful about taking it in supplement
form, as this has been linked to health problems
Taking too much iodine has been linked to the development of
subclinical hypothyroidism, which may increase your risk of heart
problems
Toxin-free sea vegetables and spirulina are among the best natural
dietary sources of iodine
<snip>
Dr. David Brownstein on Iodine Part 1/3 <time: 11:27>
http://www.youtube.com/watch?feature=player_embedded&v=0-QCZAmXHqg&list=PL1639965B7883165C
http://www.youtube.com/watch?v=kUnxqpsdoJQ&feature=BFa&list=PL1639965B7883165C&lf=player_embedded
http://www.youtube.com/watch?v=nCZv8T7-xC8&feature=BFa&list=PL1639965B7883165C&lf=player_embedded
--------------
mercola -one flu over the...
http://articles.mercola.com/sites/articles/archive/2012/02/07/recommended-tamiflu-has-flawed-results.aspx
Story at-a-glance
The antiviral drug Tamiflu has been touted as effective in reducing
complications of flu such as bronchitis and pneumonia. Sales of the
drug skyrocketed during the hyped bird- and swine flu pandemics of
2006 and 2009. But some of the evidence supporting its use has turned
out to be based on fraudulent and/or missing data
Two employees of a communications company admitted they were paid to
ghostwrite studies where the conclusion specifically had to be in
support of Tamiflu’s effectiveness
Side effects of Tamiflu include convulsions, delirium and delusions.
The death of five Japanese children and seven adults has been linked
to the drug. Disturbingly, a 2009 study found more than half of all
children taking Tamiflu experience side effects, including
neuropsychological effects such as altered behavior and nightmares.
Other rare side effects such as toxic epidermal necrolysis and
blindness have also been reported
While antiviral drugs such as Tamiflu have been used with greater
frequency, the traditional first line of defense against the flu has
been vaccines. The evidence against flu vaccines is rapidly mounting
as well, and in recent years, a number of damaging studies published
in the medical literature, negating the claim that flu vaccine is the
best form of flu prevention
<snip>
-------------
mercola - GEE... no GMO, genetically modified organism & GE foods
http://articles.mercola.com/sites/articles/archive/2012/02/07/colorado-bans-gmo-crops.aspx
----------
http://articles.mercola.com/sites/articles/archive/2012/02/08/that-isnt-wax-on-your-organic-apple.aspx
Story at-a-glance
Most people are well aware that fresh conventionally-grown produce is
more or less contaminated with pesticides. Less known is the now-
common practice of coating fresh fruits and vegetables—including
organic varieties—with edible plastic coatings to increase shelf life
So-called modified atmosphere packaging (MAP) involves controlling or
modifying the atmosphere surrounding the product to slow spoilage.
This can be accomplished by coating the food with an edible film
Four basic materials used for edible films are lipids, resins,
polysaccharides and proteins, to which a variety of antimicrobials,
plasticizers and texturizers are added
These types of coatings present several potential health hazards, the
most severe of which is the potential to promote the growth of
foodborne pathogens if misapplied
<snip>
-------------
mercola - lyme disease - Dr. Dietrich Klinghardt
http://articles.mercola.com/sites/articles/archive/2012/02/05/dr-dietrich-klinghardt-on-lyme-disease.aspx
Dr. Mercola Interviews Dr. Dietrich Klinghardt about Lyme Disease
http://www.youtube.com/watch?feature=player_embedded&v=RkXqxRfG0jk
<time: 1:35:02> <views: 8,997>
Story at-a-glance
The increased virulence of Lyme disease is likely related to the
dramatic increase in electromagnetic fields and microwave radiation.
Therefore, EMF and microwave radiation mitigation are recommended as
part of the standard treatment protocol
Lyme disease is difficult to diagnose, particularly due to "the Lyme
paradox." In order to diagnose Lyme with one of the accepted
commercial tests, you must first treat it, in order for white blood
cells to mount an appropriate immune response. Only then can a lab
test detect the presence of Lyme disease
Dr. Klinghardt successfully uses ozone and a variety of novel
approaches to treat the simplest presentation of Lyme disease, the
orthopedic forms, which typically affect the larger joints
<snip>
-------------
mercola - broken heart blues and 21 Times increased risk due to same:
http://articles.mercola.com/sites/articles/archive/2012/02/03/how-grief-can-break-your-heart.aspx
Story at-a-glance
Losing a significant person in your life raises your risk of having a
heart attack the next day by 21 times, and in the following week by 6
times, new research shows
The abrupt increase in risk of cardiovascular events like heart attack
following extreme stress may be related to the flood of stress
hormones your body is exposed to
Stress cardiomyopathy, aka “broken heart syndrome,” which causes many
of the same symptoms as a heart attack, is also known to occur shortly
following extreme emotional stress
If you’re currently grieving or going through any type of emotional
stress, it’s important to take steps to support positive mental
health, not only for your mind but also for your body
<snip>
--------------
mercola - safe exercise
http://fitness.mercola.com/sites/fitness/archive/2012/02/03/weight-room-mistakes-that-lead-to-injury.aspx
Story at-a-glance
Four common mistakes that lead to injury are skipping your warm-up,
using poor form, putting too much stress on your shoulders, and
neglecting opposing muscle groups
A proper warm-up should raise your body temperature by one to two
degrees Celsius, or just below three degrees Fahrenheit. While most
opt to use aerobic activity for their warm-up, muscle-contracting
exercises are far more effective, as it only takes 10-15 seconds of
muscular contractions to raise your body temperature by 1ºC. Included
are 16 quick warm-up exercises that can speed up and improve your warm-
up routine
Super-slow weight training is a form of high-intensity exercise that
is not only more effective than conventional strength training, but
also much safer, as it actively prevents you from accidentally harming
your joints or suffering repetitive use injury. This makes it an ideal
form of exercise for virtually everyone, regardless of age or fitness
level
Proper recovery is also important, as exercising too vigorously too
frequently can stress your body and lead to injury
Women have reportedly started weight-training in record numbers, and
weight-training related injuries among women have subsequently
increased by 63 percent
<snip>
Dr. Mercola Interviews Doug McGuff about High Intensity Exercise
http://www.youtube.com/watch?feature=player_embedded&v=fQra-ME7vIo
<time: 2:06:27>
----------
mercola - krill oil
http://articles.mercola.com/sites/articles/archive/2012/02/06/without-krill-oil-your-brain-could-degenerate.aspx
Story at-a-glance
Omega-3 fat deficiency is a contributing factor to many neurological
and psychological problems, including degenerative disorders such as
“age-related” memory loss and Alzheimer’s
Sixty percent of your brain is fat. DHA alone makes up about 15
percent to 20 percent of your brain’s cerebral cortex, as well as 30
percent to 60 percent of your retina, making it an essential nutrient
for both brain- and eye health
It’s important to get the bulk of your omega-3 fat from animal-based
sources such as krill oil, because the DHA and EPA are far more
important for your health than the plant-based ALA. While ALA can
convert into DHA/EPA, this conversion is severely impaired when you
have elevated insulin levels, which affects over 80 percent of
Americans
In two different studies, taking 800-900 mg of DHA per day for 16-24
weeks resulted in significant improvements in memory, verbal fluency
scores, and rate of learning
<snip>
-------------
mercola - vitamin D3 to see (eye_
http://articles.mercola.com/sites/articles/archive/2012/02/06/this-vitamin-found-to-rejuvenate-aging-eyes.aspx
Story at-a-glance
After receiving a vitamin D3 supplement for just 6 weeks, mice had
improved vision and reductions in retinal inflammation and levels of
amyloid beta accumulation, which is a hallmark of aging
The findings suggest vitamin D3 may help prevent age-related macular
degeneration (AMD), which is the most common cause of blindness in the
elderly
Given that vitamin D affects the accumulation of amyloid beta in the
eyes, there is reason to believe it may do so in your brain and other
areas, potentially impacting diseases like Alzheimer’s and heart
disease
Safe sun exposure is the best way to optimize your vitamin D levels,
but a safe tanning bed, or a vitamin D3 supplement, can also be used
Other important nutrients for eye health include astaxanthin, lutein,
zeaxanthin, bilberry, black currant and omega-3 fats
<snip>
=================
Wellness Resources Newsletter - Be in the know with Byron J. Richards
http://www.wellnessresources.com/emails/news/2012/newsletter_020612.htm
Fish Oil Boosts Muscle Function in Response
to Exercise
A study shows that two grams of fish oil per day combined with
strength training exercise improved muscle strength better than
exercise alone. The study was conducted on 45 women aged 64 over a 90
day period. Read more >
http://www.wellnessresources.com/health/articles/fish_oil_boosts_muscle_function_in_response_to_exercise/
DHA is Essential for Male Fertility
Researchers have demonstrated for the first time that the omega-3
essential fatty acid DHA is required for the proper formation of
healthy sperm, thereby supporting male fertility. Read more >
http://www.wellnessresources.com/health/articles/dha_is_essential_for_male_fertility/
Omega-3 Fatty Acids Help Recovery from
Sciatic Nerve Injury
The discovery that omega-3 fatty acids DHA and EPA orchestrate the
inflammation repair process in nerve cells has led scientists to
conduct new types of nerve-related experiments. A new study shows that
DHA and EPA can help the sciatic nerve recover from injury. Read more
>
http://www.wellnessresources.com/health/articles/omega-3_fatty_acids_help_recovery_from_sciatic_nerve_injury/
Excess Omega 6 Intake Speeds Telomere Damage
and Aging
Will the real evil fat please stand up? A new study shows that eating
too much food of any type will shorten your telomeres and cause you to
have accelerated aging. However, the worst type of food appears to be
excess consumption of omega-6 fatty acids, not saturated fat
http://www.wellnessresources.com/health/articles/excess_omega_6_intake_speeds_telomere_damage_and_aging/
OK so read this telomere one... OK... will
-----------
http://www.life-enhancement.com/article_template.asp?id=710
Policosanol Improves Every Measure of Blood Cholesterol
This natural extract from sugar cane is better than prescription
drugs
By Will Block
What comes to mind when you think of Cuba? Beautiful island country,
great cigars, nice people, sexy music, great rum, Ernest Hemingway,
Guantanamo Bay, sugar cane, . . . OK, stop there. Sugar is something
we can all relate to, and the more intimately, the better. Sugar is
one of nature's most lavish gifts to mankind. Can you imagine a world
without sugar? Patrick Henry might as well have said, "Give me sugar,
or give me death!"
The sugar cane (Saccharum officinalis) is already such a splendid
jewel in Mother Nature's botanical crown, it's hard to imagine that it
could match itself in any way. But in a curious and surprising way, it
has. Like all plants, sugar cane is composed of countless different
kinds of chemical compounds, many of them still unidentified and many
surely having potential value to mankind in one way or another. In
that sense, every plant species on earth should be regarded as a
potential treasure chest of as yet undiscovered chemical or medicinal
riches, there to be discovered and used to our advantage.
One might think that the sugar-cane treasure chest had long since been
fully looted, so to speak, but new discoveries continue to be made.
One discovery, not many years ago, was of a substance found in sugar
cane called policosanol, which turns out to be remarkably effective
(and very safe) in treating one of the most prevalent and serious
health problems of modern society: high cholesterol. There's a nice
irony for you: sugar cane helps cause one medical problem (obesity)
but helps prevent another (atherosclerosis).
<snip>
I put the lime in the coconut or the molasses in the coffee?
Green TEA takes a back seat?
move on..dork
-----------
http://www.familypracticenews.com/news/more-top-news/single-view/distinguish-type-1-from-type-2-diabetes-in-obese-youth/ab5b3b8571.html
Distinguish Type 1 From Type 2 Diabetes in Obese Youth
By: BRUCE JANCIN, Family Practice News Digital Network
STEAMBOAT SPRINGS, COLO. – New-onset type 1 diabetes in an obese youth
cannot reliably be distinguished from pediatric type 2 diabetes on
clinical grounds in this era of epidemic obesity.
"The only way to distinguish obese type 1 diabetes from type 2
diabetes is to measure diabetes autoantibodies. And those autoantibody
panels are commercially available now. Signs and symptoms, diabetic
ketoacidosis, family history – they don’t really help you. We get an
autoantibody panel routinely in obese kids above age 10 presenting
with new-onset diabetes," said Dr. Charlotte M. Boney, chief of the
division of pediatric endocrinology and metabolism at Hasbro
Children’s Hospital in Providence, R.I.
Diabetic ketoacidosis is widely thought of as incompatible with type 2
diabetes. Not true. Close to 20% of youth with type 2 diabetes present
with DKA. Similarly, while a history of recent weight loss is
considered a classic presenting symptom of type 1 diabetes, it’s also
present in about one-quarter of young people presenting with type 2
diabetes, Dr. Boney noted.
The presence of pancreatic autoantibodies spells type 1 diabetes
metabolically, even if the patient appears phenotypically to have type
2 disease.
"Some pediatric endocrinologists call this ‘type one-and-a-half’
diabetes. No, no, no. Let’s not make things any weirder than they
already are. They have autoimmune diabetes, which is clearly type 1
diabetes. It just happens to be a little more complicated in them
because they also have the morbidity of obesity," she explained at the
meeting on practical pediatrics sponsored by the American Academy of
Pediatrics.
The obesity epidemic has muddied the diagnostic waters, because now
20%-30% of patients with new-onset type 1 diabetes are obese, as is a
similar proportion of the general pediatric population. At the same
time, the obesity epidemic has led to an increase in type 2 diabetes.
But it’s important to bear in mind that most youths with new-onset
diabetes still have type 1 disease, she said.
In the landmark prospective The SEARCH For Diabetes In Youth study,
nearly all children who presented under age 10 years had type 1
diabetes. Among 10- to 19-year-olds, the proportion with type 2
disease was 15% among whites, but considerably greater among racial
minorities: 58% among African Americans, 46% in Hispanics, 70% in
Asian/Pacific Islanders, and 86% among Native Americans (JAMA
2007;297:2716-24).
http://jama.ama-assn.org/content/297/24/2716.long
In the ongoing, multicenter, National Institutes of Health–sponsored
Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)
study, which enrolled 1,206 subjects with a presumptive diagnosis of
type 2 diabetes, 9.8% proved to be positive for GAD-65and/or
insulinoma-associated protein 2 autoantibodies. They had to be
excluded from participation in the treatment phase (Diabetes Care
2010;33:1970-5).
http://care.diabetesjournals.org/content/33/9/1970.long
As a practical approach to the initial therapy of young patients with
new-onset diabetes, Dr. Boney urged that those with DKA and ketosis
should be started on intravenous fluids and insulin, regardless of
their age and body habitus. If they are over age 10 and obese,
however, pancreatic autoimmunity should be ruled out before
transitioning to long-term therapy. For autoantibody-negative patients
whose clinical picture is consistent with type 2 diabetes, the
treatment is metformin, the only Food and Drug Administration–approved
therapy for children. Extensive experience shows that it’s a very safe
drug, she said.
The TODAY trial is designed to determine whether the best treatment
for type 2 diabetes in youth is metformin alone, metformin plus
rosiglitazone, or metformin and an intensive lifestyle intervention
aimed at achieving a 7%-10% weight loss.
The use of metformin to try to prevent diabetes in obese children with
insulin resistance and the metabolic syndrome is the subject of large
ongoing clinical trials. Until the results come in, Dr. Boney said she
sees no role for off-label prescribing of metformin, given that weight
loss and exercise are quite effective in improving insulin
sensitivity.
Maturity Onset Diabetes of the Young, or MODY, is worth considering in
white youth who are pancreatic autoantibody–negative and have a strong
history of parental non–type 1 diabetes. MODY is a single-gene
disorder that causes diabetes and is inherited from a parent.
"There are a lot of experts in the MODY field that think we’re grossly
underdiagnosing monogenic diabetes," said Dr. Boney.
The treatment for MODY is not insulin or metformin, but rather oral
sulfonylureas, although those agents are not FDA-approved for use in
children, she observed.
Dr. Boney reported having no financial conflicts.
<snip>
=============
Someone sent me this... and it was interesting to watch:
https://www.youtube.com/watch?v=AZU0c8DAIU4&feature=email
Mind blowing speech by Robert Welch in 1958 predicting Insiders plans
to destroy America
Proof that the NEW WORLD ORDER has been planned by the elite. Robert
Welch, Founder of The John Birch Society, predicted today's problems
with uncanny accuracy back in 1958 and prescribed solutions in 1974
that are very similar to Ron Paul's positions today. This is proof
that there are plans in place by the elite to systemically disassemble
US sovereignty. I wonder who those elite are.
<snip>
http://en.wikipedia.org/wiki/John_Birch_Society
http://en.wikipedia.org/wiki/John_Birch_Society#2009.E2.80.93present
The Society has been active in supporting the auditing[51] of, and
aims to eventually dismantle, the Federal Reserve System. The JBS
believes that the U.S. Constitution gave only Congress the ability to
coin money, and did not intend for it to delegate this power to a
banking monopoly, or to transform it into a fiat currency not backed
by gold or silver.
The JBS was a co-sponsor of the 2010 Conservative Political Action
Conference, ending its decades-long exile from the mainstream
conservative movement.
http://en.wikipedia.org/wiki/Federal_Reserve_System
http://en.wikipedia.org/wiki/Fiat_money
http://en.wikipedia.org/wiki/Conservative_Political_Action_Conference
I wonder if JBS supports
http://www.hillsdale.edu/news/imprimis/archive/issue.asp?year=2012&month=01
January 2012
Charles Murray
American Enterprise Institute
Do We Need the Department of Education?
<snip>
8 hits on a search of the JBS on hillsdale:
#1 of 8
http://www.hillsdale.edu/news/imprimis/archive/issue.asp?year=1980&month=06
June 1980
The News of Politics vs. The Politics of News
Lyn Nofziger
Not much in it or #2
http://www.hillsdale.edu/images/userImages/whadra/Page_7050/Steve%20Hayward.pdf
and the rest aren't related at all.
under
http://en.wikipedia.org/wiki/John_Birch_Society#Notable_members
I see the DUKE... last... JW..
==============
wonder how the duke would view this:
Benton Harbor, Michigan
Total population: 10826 (All urban)
Company town: Headquarters for WHIRLPOOL appliances
All Whirlpool factories in Benton Harbor have been shut down
and labor outsourced to other countries.
Whirlpool has received multi-million dollar grants from
the Federal government to help build employment in
Benton Harbor
2009: $19.3 million federal grant
2010: $20 million state grant
Whirlpool has not paid US income tax since 2008
Annual sales: $18 billion annual sales
% living in poverty: 90% ($10,000 per capita income)
% unemployed: 60%
% receiving food stamps: 99%
The video report: http://rt.com/news/whirlpool-neglect-outsourcing-benton-417/
<snip>
I haven't watched the dvd yet... but maybe when i read this?
==================
Bring Jobs Back To America By Hiring Chinese
http://abcnews.go.com/WNT/video/us-bridges-roads-built-chinese-firms-14594513?tab=9482930?ion=1206853&playlist=14594944
ABC shows obama saying let's build stuff... then chinese getting the
jobs and union
memebers pissed off. LOL
$9 billion in bridges being built by chinese... LOL
I guess the union workers priced themselves outa the market.... LOL
==================
SEE THE RED TYPE. Americans are going to pay unprecedented taxes so
the Federal Government can spend more to create more phony jobs and
raise the GDP with government-funded ventures. America is now a slave
state.
FEBRUARY 2, 2012
http://online.wsj.com/article/SB10001424052970204740904577195352148844134.html?mod=googlenews_wsj
$5 Trillion and Change
Obama's four years have seen the four highest deficits since 1946.
The political strategy behind Obamanomics was always simple: Call for
"stimulus" to rescue the economy, run up the debt with the biggest
spending blitz in 60 years, and then when the deficit explodes call
for higher taxes. The Congressional Budget Office annual review
released yesterday shows this is all on track.
CBO reports that annual spending over the Obama era has climbed to a
projected $3.6 trillion this fiscal year from $2.98 trillion in fiscal
2008, or more than 20%. The government spending burden has averaged
24% of GDP, up from an average of about 20%. This doesn't include the
$2 trillion tab for ObamaCare.
All of this has increased the federal debt by about $5 trillion in a
mere four years. Thanks to higher revenues, the federal deficit will
decline to $1.08 trillion in 2012, or 7% of GDP. But that is still the
highest deficit since 1946—except for the previous three years. In
other words, the four years of the Obama's Presidency will mark the
four highest years in spending and deficits as a share of the economy
since Harry Truman sat in the Oval Office.
We pause from this gloom for some good news: Despite the abuse they've
taken, House Republicans have made some fiscal progress. CBO estimates
that overall federal spending in 2012 will grow by only $3 billion, or
less than 1%, which compares with double digit increases during the
Obama-Pelosi years. Republicans have also tried to reform
entitlements, but Democrats wanted a $1 trillion tax hike ransom for
even modest cuts, which was wisely rejected.
The other part of the fiscal story is that revenues have been in the
tank for five years. In 2012 revenues will hit $2.52 trillion down
from $2.57 trillion in 2007. Revenues are still only 16.3% of GDP,
about two percentage points below the norm.
The drought has two main causes. First, the anemic recovery in jobs
and investment isn't spinning off enough new output (1.7% growth last
year) to boost tax receipts anywhere near their historic level.
Second, a series of non-stimulative tax cuts—tax rebates in 2008 and
2009, and payroll tax holidays in 2011 and this year—have depleted the
Treasury with little economic benefit. These tax cuts don't change the
incentive at the margin to work or invest, and they thus have little
feedback effect in revenues from faster growth.
The most amusing part of the CBO's report is its projection that the
deficit will fall to $269 billion by 2015, or a mere 1.5% of GDP, if
current law holds. But this is a fiscal fantasy because current law
never holds.
CBO predicts, for example, that all the Bush tax cuts will go away
next year. The Alternative Minimum Tax will supposedly be allowed to
hit 30 million tax filers (up from four million now) with an income as
low as $75,000 a year. Under those assumptions total federal revenues
rise by $1 trillion over the next three years, $1.5 trillion over five
years, and $3.6 trillion over 10 years. You can't get anywhere near
that level of revenues without a much bigger tax increase on the rich
and the middle class, or an extended boom in the range of 5% to 6%
annual growth.
Even the Keynesians who run CBO concede that the 2013 tax hike—on
capital gains, dividends, estates and small business—would knock
economic growth down to 1% next year and raise unemployment to 9.1%
(from 8.5%). That means about 750,000 more jobless Americans. You
can't have such a lousy economy and cut the deficit in half.
CBO also indulges in the fantasy that discretionary spending will fall
by nearly $2 trillion over the next decade—with almost all the cuts
after 2015. About $1.25 trillion of those cuts come from the automatic
across-the-board reductions that Congress and Mr. Obama agreed to last
year. But wait. More than half of those cuts will come from the
military budget and even Defense Secretary Leon Panetta has said these
reductions could be "devastating" to national security.
To sum it all up, CBO's facts plainly show that Mr. Obama has the
worst fiscal record of any President in modern times. No one else is
even close.
<snip>
====================
10,355 - hits: mucin cancer - pubmed
http://www.ncbi.nlm.nih.gov/pubmed?term=mucin%20cancer
1,656 hits: mucin muc1 cancer
http://www.ncbi.nlm.nih.gov/pubmed?term=mucin%20muc1%20cancer
1 hit: mucin muc1 cancer microbiota
http://www.ncbi.nlm.nih.gov/pubmed?term=mucin%20muc1%20cancer%20microbiota
#1 of 1
http://www.ncbi.nlm.nih.gov/pubmed/20703838
Curr Gastroenterol Rep. 2010 Oct;12(5):319-30.
Intestinal goblet cells and mucins in health and disease: recent
insights and progress.
Kim YS, Ho SB.
Source
Genemed Biotechnologies, 458 Carlton Court, South San Francisco, CA
94080, USA. youn...@ucsf.edu
Abstract
The mucus layer coating the gastrointestinal tract is the front line
of innate host defense, largely because of the secretory products of
intestinal goblet cells. Goblet cells synthesize secretory mucin
glycoproteins (MUC2) and bioactive molecules such as epithelial
membrane-bound mucins (MUC1, MUC3, MUC17), trefoil factor peptides
(TFF), resistin-like molecule beta (RELMbeta), and Fc-gamma binding
protein (Fcgbp). The MUC2 mucin protein forms trimers by disulfide
bonding in cysteine-rich amino terminal von Willebrand factor (vWF)
domains, coupled with crosslinking provided by TFF and Fcgbp proteins
with MUC2 vWF domains, resulting in a highly viscous extracellular
layer. Colonization by commensal intestinal microbiota is limited to
an outer "loose" mucus layer, and interacts with the diverse
oligosaccharides of mucin glycoproteins, whereas an "inner" adherent
mucus layer is largely devoid of bacteria. Defective mucus layers
resulting from lack of MUC2 mucin, mutated Muc2 mucin vWF domains, or
from deletion of core mucin glycosyltransferase enzymes in mice result
in increased bacterial adhesion to the surface epithelium, increased
intestinal permeability, and enhanced susceptibility to colitis caused
by dextran sodium sulfate. Changes in mucin gene expression and mucin
glycan structures occur in cancers of the intestine, contributing to
diverse biologic properties involved in the development and
progression of cancer. Further research is needed on identification
and functional significance of various components of mucus layers and
the complex interactions among mucus layers, microbiota, epithelial
cells, and the underlying innate and adaptive immunity. Further
elucidation of the regulatory mechanisms involved in mucin changes in
cancer and inflammation may lead to the development of novel
therapeutic approaches.
PMID: 20703838
Free PMC Article
http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20703838/?tool=pubmed
74 hits; mucin microbiota
http://www.ncbi.nlm.nih.gov/pubmed?term=mucin%20microbiota%20
57 hits : mucin - p ng
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=mucin&start=0&
13 0f 57 have: muc1 with mucin - p ng
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=mucin+muc1&start=0&
19 with muc1: p ng
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=+muc1&start=0&
Lactobacilli Bifidobacteria Streptococci - 28 hits: p ng
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=Lactobacilli+Bifidobacteria+Streptococci&start=0&
http://www.ncbi.nlm.nih.gov/pubmed/16973917
Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G315-22. Epub
2006 Sep 14.
The VSL#3 probiotic formula induces mucin gene expression and
secretion in colonic epithelial cells.
Caballero-Franco C, Keller K, De Simone C, Chadee K.
Source
Institute of Parasitology, McGill University, Saint Anne de Bellevue,
Quebec, Canada.
Abstract
Several studies have stressed the importance of the microbiota in the
maintenance of the gastrointestinal epithelium. Administration of
probiotic bacteria, supplements composed of microbiota constituents,
was previously shown to diminish symptoms in patients suffering from
inflammatory bowel diseases. This raises the possibility that
probiotics may play an active role in enhancing the intestinal barrier
at the mucosal surface. In this study, we investigated whether the
clinically tested VSL#3 probiotic formula and/or its secreted
components can augment the protective mucus layer in vivo and in
vitro. For in vivo studies, Wistar rats were orally administered the
probiotic mixture VSL#3 on a daily basis for seven days. After
treatment, basal luminal mucin content increased by 60%. In addition,
we exposed isolated rat colonic loops to the VSL#3 probiotic formula,
which significantly stimulated colonic mucin (MUC) secretion and MUC2
gene expression; however, MUC1 and MUC3 gene expression were only
slightly elevated. The effect of the VSL#3 mucin secretagogue was also
tested in vitro by use of LS 174T colonic epithelial cells. In
contrast to the animal studies, cultured cells incubated with VSL#3
bacteria did not exhibit increased mucin secretion. However, the
bacterial secreted products contained in the conditioned media
stimulated a remarkable mucin secretion effect. Among the three
bacterial groups (Lactobacilli, Bifidobacteria, and Streptococci)
contained in VSL#3, the Lactobacillus species were the strongest
potentiator of mucin secretion in vitro. A preliminary
characterization of the putative mucin secretagogue suggested that it
was a heat-resistant soluble compound, which is not sensitive to
protease and DNase treatment. These findings contribute to a better
understanding of the complex and beneficial interaction between
colonic epithelial cells and intestinal bacteria.
PMID: 16973917
Free full text
http://ajpgi.physiology.org/cgi/pmidlookup?view=long&pmid=16973917
We have seven hits in the p ng:
7 hits: VSL#3 probiotic formula
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=VSL%233&start=0&
VSL#3 - 125 hits - pubmed:
http://www.ncbi.nlm.nih.gov/pubmed?term=vsl%233
http://www.vsl3.com/
http://www.vsl3.com/about.asp
http://www.vsl3.com/research.asp
http://www.vsl3.com/uses-vsl.asp
Who Uses VSL#3®?
The probiotic medical food for the dietary management of Ulcerative
Colitis, Irritable Bowel Syndrome (IBS), or an Ileal Pouch
The human gastrointestinal (GI) system is populated by thousands of
billions of beneficial bacteria that act as a protective barrier
throughout the GI system. These bacteria perform a variety of
important biochemical functions from enhancing the protective
intestinal barrier to modulating intestinal inflammation and reducing
colonic permeability.
Under some conditions the number of pathogenic ("bad") bacteria in a
person’s intestines can begin to outnumber the good bacteria. Numerous
studies have implicated the overgrowth of pathogenic bacteria in
certain intestinal disorders.21,40 Studies have shown that patients
with ulcerative colitis (UC), irritable bowel syndrome (IBS), or an
ileal pouch tend to have a decreased concentration of beneficial
bacteria.4,14,52 This deficiency could lead to more flare-ups and
issues with diarrhea, frequency, and urgency.
VSL#3® is the only medical food that can restore beneficial intestinal
bacteria in UC, IBS and pouch patients with optimal quantities and
types of beneficial bacteria.
Ulcerative Colitis Patients – Several published studies have showed
that daily ingestion of VSL#3® can aid in the dietary management of
ulcerative colitis (UC).3,63,66
Patients with irritable bowel syndrome – Patients involved in two
double blind placebo-controlled trials reported satisfactory relief of
gas and bloating associated with IBS.33,68,69
Patients with an Ileal Pouch – VSL#3® has been recognized by the
American College of Gastroenterology Practice Parameter as a tool for
the dietary management of pouchitis. Three double-blind, placebo
controlled trials have shown that VSL#3® is important for the dietary
management of pouchitis. 19,20,44
Other Studies – Read other studies discussing the use of probiotics
and VSL#3® for the dietary management of serious intestinal disorders.
<snip>
#1 of 125 hits for VSL#3 on pubmed:
http://www.ncbi.nlm.nih.gov/pubmed/22247743
Probiotics Antimicrob Proteins. 2011 Mar;3(1):1-7.
Gut microbiota is not modified by Randomized, Double-blind, Placebo-
controlled Trial of VSL#3 in Diarrhea-predominant Irritable Bowel
Syndrome.
Michail S, Kenche H.
Abstract
Irritable Bowel Syndrome (IBS) is a common condition that negatively
impacts the quality of life for many individuals. The exact etiology
of this disorder is largely unknown; however, emerging studies suggest
that the gut microbiota is a contributing factor. Several clinical
trials show that probiotics, such as VSL#3, can have a favorable
effect on IBS. This double-blind, randomized placebo-controlled study
has been conducted in diarrhea-predominant IBS subjects in order to
investigate the effect of VSL#3 on the fecal microbiota. The bacterial
composition of the fecal microbiota was investigated using high-
throughput microarray technology to detect 16S RNA. Twenty four
subjects were randomized to receive VSL#3 or placebo for 8 weeks. IBS
symptoms were monitored using GSRS and quality of life questionnaires.
A favorable change in Satiety subscale was noted in the VSL #3 groups.
However, the consumption of the probiotic did not change the gut
microbiota. There were no adverse events or any safety concerns
encountered during this study. To summarize, the use of VSL#3 in this
pilot study was safe and showed improvement in specific GSRS-IBS
scores in diarrhea-predominant IBS subjects. The gut microbiota was
not affected by VSL#3 consumption suggesting that the mechanism of
action is not directly linked to the microbiota.
PMID: 22247743
Free PMC Article
http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22247743/?tool=pubmed
The --- alt.support.crohns-colitis group:
441 hits - vsl#3 - cc ng: (only 7 hits on p ng)
http://groups.google.com/group/alt.support.crohns-colitis/search?q=vsl%233&start=0&
chrono order (latest backwards) vsl#3
http://groups.google.com/group/alt.support.crohns-colitis/search?q=vsl%233&start=0&scoring=d&
http://www.eurekalert.org/pub_releases/2011-10/uob-cap101911.php
Could a probiotic be used to treat inflammatory bowel disease?
Scientists have been unclear for some time about how most probiotics
work. A new study has found a scientific 'design' for a probiotic
that
could be used to treat inflammatory bowel disease (IBD), such as
Crohn's disease.
The research by academics at the University of Bristol's School of
Veterinary Sciences and the School of Clinical Medicine is published
online in the journal PLoS ONE.
Most probiotics on the market, such as Lactobacillus and
Bifidobacterium, are lactic acid bacteria. Although probiotics have
been shown to successfully maintain remission in IBD, evidence of
their effectiveness in active disease is rare. The researchers have
found that this is because an increase in iron levels, which happens
during active IBD, inhibits the growth of probiotic bacteria,
including Lactobacillus.
Iron levels increase in the intestine during inflammation, bleeding,
during stress and when people are taking iron supplements. Iron is
critically important to the growth of most species of bacteria,
including pathogens, and its availability is what restricts their
growth. It is well known that pathogens increase growth rate by up to
8,000 times when exposed to increased levels of iron. Lactic acid
bacteria are unusual as they have evolved not to require iron, and so
do not increase growth rate when exposed to it.
Dr Tristan Cogan, Research Fellow in the School of Veterinary
Sciences, said: "When we started our study we considered the
properties that a probiotic would need to treat IBD. Most
importantly,
it would need to be able to survive and grow in the presence of high
levels of iron and to reduce inflammation. We then worked out how to
test bacteria to see whether it had these properties.
"The difficult step was finding a bacterium that had all of the
properties that we wanted. Now we have found something that looks
like
it should work, our next step will be to test the probiotic in
clinical trials."
The researchers found that a range of probiotic strains of lactic
acid
bacteria cannot respond to increased iron levels. The study then
identified a strain, which the academics have patented, that can and
showed that it has probiotic and immunomodulatory properties, and can
reduce pro-inflammatory responses to pathogens associated with IBD.
The researchers suggest that iron response is the factor that
prevents
probiotics from being useful in treating disease, and that their
bacterium could be a novel probiotic treatment for active intestinal
disease.
<snip>
Finding iron probiotic cogan?
OK. another october surprise... 2011 this time:
http://www.ncbi.nlm.nih.gov/pubmed/22039501
PLoS One. 2011;6(10):e26507. Epub 2011 Oct 19.
Identification and characterisation of an iron-responsive candidate
probiotic.
Bailey JR, Probert CS, Cogan TA.
Source
Mucosal Microbiology, School of Veterinary Sciences, University of
Bristol, Bristol, United Kingdom.
Abstract
BACKGROUND:
Iron is an essential cofactor in almost all biological systems. The
lactic acid bacteria (LAB), frequently employed as probiotics, are
unusual in having little or no requirement for iron. Iron in the human
body is sequestered by transferrins and lactoferrin, limiting
bacterial growth. An increase in the availability of iron in the
intestine by bleeding, surgery, or under stress leads to an increase
in the growth and virulence of many pathogens. Under these high iron
conditions, LAB are rapidly out-competed; for the levels of probiotic
bacteria to be maintained under high iron conditions they must be able
to respond by increasing growth rate to compete with the normal flora.
Despite this, iron-responsive genera are poorly characterised as
probiotics.
METHODOLOGY/PRINCIPAL FINDINGS:
Here, we show that a panel of probiotics are not able to respond to
increased iron availability, and identify an isolate of Streptococcus
thermophilus that can increase growth rate in response to increased
iron availability. The isolate of S. thermophilus selected was able to
reduce epithelial cell death as well as NF-κB signalling and IL-8
production triggered by pathogens. It was capable of crossing an
epithelial cell barrier in conjunction with E. coli and downregulating
Th1 and Th17 responses in primary human intestinal leukocytes.
CONCLUSIONS/SIGNIFICANCE:
We propose that an inability to compete with potential pathogens under
conditions of high iron availability such as stress and trauma may
contribute to the lack of efficacy of many LAB-based probiotics in
treating disease. Therefore, we offer an alternative paradigm which
considers that probiotics should be able to be competitive during
periods of intestinal bleeding, trauma or stress.
PMID: 22039501
Free PMC Article
http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22039501/?tool=pubmed
or
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0026507
18 hits: "Cogan TA"[Author]
http://www.ncbi.nlm.nih.gov/pubmed?term=%22Cogan%20TA%22%5BAuthor%5D
I guess cogan didn't know what met
http://www.aalatimes.com/2011/11/06/could-a-probiotic-be-used-to-treat-inflammatory-bowel-disease/
Could a probiotic be used to treat inflammatory bowel disease?
Sunday, November 6, 2011
<snip>
I guess Tristan doesn't have the strategy of nobel prize winner (1908)
of elie metchnikoff?
http://www.bris.ac.uk/vetscience/people/tristan-a-cogan/index.html
Tristan versus Eli?
http://en.wikipedia.org/wiki/%C3%89lie_Metchnikoff
What would elie metchnikoff do in this ironic situation?
Shall i ask?
But i already KNOW....so?
Iron versus lactic acid bacteria:
http://en.wikipedia.org/wiki/Lactic_acid
http://en.wikipedia.org/wiki/Lactic_acid_bacteria
95 hits: elie metchnikoff gut flora - all groups:
http://groups.google.com/groups/search?q=elie+metchnikoff+gut+flora&btnG=Search&sitesearch=
ONLY one of those is mine. LOL
http://groups.google.com/groups/search?q=elie+metchnikoff+gut+flora+randall&btnG=Search&sitesearch=
But there are two there:
http://groups.google.com/groups/search?q=+metchnikoff+psoriasis+randall&btnG=Search&sitesearch=
And one of them is a response from Russian and p ng friend:
Mikhail Inq:
http://groups.google.com/groups/profile?enc_user=6a3bFQ8AAAAqB9AcXjMSzBAJuMCsyIbP
Mikhail Inq also wrote a book (e book iirc) in this realm:
And that is a nick name:
27 hits for the nick name:
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=mikhail+Inq&start=0&
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/cc61052dc43999e8
mp2000:
My nickname is Mikhail Inq, I am russian, I live and work in Moscow.
Almost 40 years I have psoriasis.
I have 30-year's positive experience of a elimination diet and
cleansing methods.
As a consequence, my psoriasis is insignificant.
Now I have one-year positive experience of Pagano regimen
(cleansing,elimination diet, teas etc.).
In Russian Internet there is very few of information devoted to a
psoriasis.
In may 2000 I have based and I support a russian site "Psoriasis as
intestinal disease" - www.psora.df.ru.
On this site I have presented brief translation 5, 6 and 7 chapters,
and also some Appendixs from this book.
In Russia the treatment of a psoriasis of this method only starts.
The information and exchange of experience is extremely necessary
(not
only for Russians).
When you decide (may be after 2-3 months) that you have positive (or
negative) experience of application Pagano
regimen, please, fill special form www.psora.df.ru/form_qa_e.html (on
English - of course)
Your answer (on English) will be placed on "Exchange of
Experience" page www.psora.df.ru/eoe.html. Read this page.
The translation (on Russian) - on page www.psora.df.ru/que_ans.html
It will help to other with treatment from a psoriasis.
Best wishes for you.
<snip>
And none of his sites (above) open without a 404 error. Shucks..
And the only other hit i get is this one from the NPF forum from
LAZZA:
who said:
https://www.inspire.com/groups/talk-psoriasis/discussion/finding-the-way-to-heal-naturally/
[...] By Lazza
Reply 1994255
February 23, 2011 at 8:24 am
Report post
I have been doing a similar diet for the past 18 months with great
success (95% improvement in PPP symptoms). However it isn't exactly
the same. Despite what Pagano says I've had no issues with berries at
all. I also discovered potatoes are harmless to me. Dairy? Absolutely
poisonous. Gluten? Dunno, but I don't eat it any more. And so I
suggest expanding your horizons a bit. I've read the Pagano book and
found some of his suggestions to be strange and poorly explained,
albeit I do recommend his book overall.
While on Pagano, he is spot on wrt linking colon health with
psoriasis. I had irritable bowel syndrome for years and so I knew my
colon was messed up. Diet and probiotics cleared that up 90%. I also
took light doses of grapefruit seed extract and olive leaf extract to
kill off unwanted pathogens. However recently I changed this to simply
do a heavier dose of olive leaf extract, in response to a (suspected)
mild lung infection following a cold. Well it zapped whatever was
bothering my lungs, and I also noticed my psoriasis improving. Google
"olive leaf extract" and you will see that it is safe. At any rate,
keeping your colon flora healthy is important. In his thread and
research paper Mikhail Inq discusses the link between colon issues and
psoriasis. I am a true believer in it.
<snip>
OK, this one works:
http://www.psora.df.ru/que_ans_e.html
Are these all the same? Is roy cohen also Inq?
Duh, it says so... LoL
And these guys?
[...]Michael S., New York The author of a site has Dec 23, 2000
Mikhail Inq, Moscow, Russia inq-at-bmail.ru Dec 20, 2000
Roy Сohen, Сranbury, NJ USA roy-at-gghc.com Dec 15, 2000
Tim Nesielheum Nesielheum-at-aol.com Dec 30, 2000
Patsy snakeman-at-penn.com Jan 7,2001
Tom The author of a site has Mar 12, 2001
Lil Jen
<snip>
IIRC, tim N. has been on the p ng
Let's see: 315 times for
Tim Nesielheum (he's not a russian but did the pagano program i'm
guessing)
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=Tim+Nesielheum%09&start=0&
This one comes up as an oddity:
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/44d0a2e9dad3ec03
from marlon with subject matter:
attn: mikkel - very superb active newsgroups - ig dud vosfi - (1/1)
And all or mostly faked:
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/44d0a2e9dad3ec03?dmode=source
And not much happening at nuzer.net
ONly 487 hits for ALL groups:
nuzer.net
http://groups.google.com/groups/search?qt_s=1&q=nuzer.net+
One link for nuzer goes here:
VideoStash.Net is a video archive that updates often containing
amateur homemade sex and porn videos available for download.
OK back to Mikhail and 28 hits for him on ALL google groups:
http://groups.google.com/groups/search?hl=en&ie=UTF-8&q=mikhail+Inq+psoriasis&btnG=Search&sitesearch=
And his e-book
here:
http://www.psorias.info/
http://www.psorias.info/9785905504020_MPP_Part1_Systemic_psoriatic_process_eng.pdf
part II
http://www.psorias.info/9785905504044_MPP_Part2_Local_processes_eng.pdf
WELL.... Mikhail Peslyak has some really nice illustrations and
diagrams:
http://www.scribd.com/doc/25421572/Model-of-pathogenesis-of-psoriasis-Part-1-Systemic-psoriatic-process-Edition-e3-2-Mikhail-Peslyak
http://www.researchgate.net/topic/Models_of_pathogenesis_of_psoriasis/
I should have LOOKed at this thread first:
duh..
Tues, Feb 2 2010 9:13 am
Subject: Re: New e-book about pathogenesis of psoriasis
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/5106159adc141d94
Mikhail said:
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/1b62daa1078b874b
from
http://groups.google.com/groups/profile?hl=en&enc_user=6a3bFQ8AAAAqB9AcXjMSzBAJuMCsyIbP
==========
Biting the hand that nurtures YOU?
http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2012/01/29/BA9P1N089K.DTL&tsp=1
[...] Friends and relatives said Susan Poff and Robert Kamin of
Oakland were the perfect pair to adopt a foster child.
They had dedicated their careers to helping others escape poverty, she
as a physician assistant in a city-run clinic in the Tenderloin and he
as a clinical psychologist for inmates in the San Francisco County
Jail system.
But now, less than a decade after they adopted, their 15-year-old son
stands accused of strangling both Poff, 50, and Kamin, 55, then hiding
their bodies in the back of the family's PT Cruiser.
[...] Co-workers said Poff and Kamin were having some arguments with
their son, some of it having to do with him spending too much time in
the Occupy Oakland encampment, but nothing that sounded beyond the
scope of typical teenage rebelliousness.
<snip>
Occupy the toilet poisons this son's mind?
Seems likely.
http://occupywallst.org/
Do they even know they suck?
NOPE
http://occupywallst.org/about/
Principles of Solidarity
http://www.nycga.net/resources/principles-of-solidarity/
Statement of Autonomy
http://www.nycga.net/resources/statement-of-autonomy/
Declaration of the Occupation
http://www.nycga.net/resources/declaration/
Everyone has the Right to Occupy Space, Safely
http://occupywallst.org/article/everyone-has-right-occupy-space-safely/
As they support obama and he them then it's axiomatic
http://en.wikipedia.org/wiki/Occupy_Wall_Street
And now foster parents of a 15 year old occuparian have died.
LOOKs like a low IQ type:
http://i.dailymail.co.uk/i/pix/2012/01/31/article-0-118A13E0000005DC-441_306x423.jpg
See more pictures of the DEAD mother and home:
http://www.dailymail.co.uk/news/article-2094862/Moses-Kamin-15-murdered-parents-hid-bodies-car-argument-suspended-school.html
<snip>
It occupy worked to make the pie then let them eat their own pie.
But if they want YOUR pie via obamma as their momma....then
tell them to go BACK to the USSR boys...
As this 200 pound sucky foster brat, Moses Kamin is NOW living for
free the
rest of his sucky LIFE in public prisons paid for by FREE AMERICANS
http://sfist.com/2012/02/02/oakland_teen_arraigned_admitted_gui.php
If he was a muslim they'd chop his head off on friday afternoon the
market square.
Or they use to do that?
Don't see it here:
http://en.wikipedia.org/wiki/Sharia#Penalties
But that doesn't mean it doesn't happen.
This person witnessed a friday punishment:
http://www.tariqramadan.com/An-International-call-for,264.html?lang=fr
=====================
0 to 100 mph and back to 0 in less then five seconds?
No way...
check it out... on this carbon youtube:
http://www.psoriasis-healing.com/
<time: 44:44> <views: 33,950>
Carbon saves:
Katherine Legge crash Road America 2006
http://www.youtube.com/watch?v=ZCI-QSt0hpE
<time: 1:16> <48,645 views>
http://en.wikipedia.org/wiki/Katherine_Legge
Wow... carbon is amazing and it's global warming so
why don't we have nuclear power?
Because that Genie isn't safe and we're not transparent on this topic.
Why?
I don't know..
You would think the news pimps would be open and not closed like
bigots?
But their so bigotted on so many points.
ok.. move on dork dot.
==============
OK so my TIME is still timely.
via garrett lisi
http://www.cs.virginia.edu/~robins/A_Geometric_Theory_of_Everything.pdf
l
A Geometric Theory of Everything
by A. Garrett Lisi and James Owen Weatheral
<snip>
Nice kitty:
http://jamesowenweatherall.com/
co-author
http://uci.academia.edu/JamesWeatherall
<snip>
http://uci.academia.edu/JamesWeatherall/Papers/683487/On_the_Status_of_the_Geodesic_Principle_in_Newtonian_and_Relativistic_Physics
On the Status of the Geodesic Principle in Newtonian and Relativistic
Physics by James Owen Weatherall |
<snip>
Will they go TOE head once the LHC pumps out a higgs boson?
I guess.
http://www.scientificamerican.com/article.cfm?id=higgs-boson-signal-gains
Signal for Higgs Boson Particle Gains Strength
The latest analyses from the Large Hadron Collider boost the case for
the particle's existence, but there's no new data
By Geoff Brumfiel and Nature News Blog | February 7, 2012
Today the two main experiments at the Large Hadron Collider (LHC), the
world’s most powerful particle accelerator, submitted the results of
their latest analyses. The new papers boost the case for December’s
announcement of a possible Higgs signal, but let’s not get too
excited.
http://www.scientificamerican.com/topic.cfm?id=large-hadron-collider
https://cdsweb.cern.ch/collection/CMS%20Papers?ln=en
http://www.scientificamerican.com/article.cfm?id=higgs-lhc
First, there’s no new data in there—the LHC stopped colliding protons
back in November, and these latest results are just rehashes that
earlier run. In the case of the Compact Muon Solenoid (CMS),
physicists have been able to look at another possible kind of Higgs
decay, and that allows them to boost their Higgs signal from 2.5σ to
3.1σ. Taken together with data from the other detector, ATLAS, Higgs
overall signal now unofficially stands at about 4.3σ. In other words,
if statistics are to be believed, then this signal has about a 99.996
percent chance of being right.
It all sounds very convincing, but keep your hat on, because the fact
is that statistical coincidences happen every day. Over at Cosmic
Variance, Sean Carroll points out that there is a 3.8σ signal in the
Super Bowl coin toss. Does that mean that they’ve discovered a super-
partner to the bowl? No. (If you don’t get that joke, don’t worry, it
was written only as punishment for those who would).
http://blogs.discovermagazine.com/cosmicvariance/2012/02/04/a-3-8-sigma-anomaly/
After the LHC starts this spring, we’ll be much closer to knowing
what’s actually going on. Right now, scientists are meeting in
Chamonix, France to decide at what power to run the collider this
coming year. The latest rumours are that the machine will push from 7
to 8 TeV, and it will also increase its luminosity (the number of
collisions per pass).
http://indico.cern.ch/conferenceOtherViews.py?view=standard&confId=164089
For a little context more about what’s going on, check out this video
of my trip back in November:
<snip>
Hunting for the Higgs
http://www.youtube.com/watch?v=LXdrk6LC1eU&feature=player_embedded
<time: 2:54> <views: 9326>
randall... wow... really kewl stuff ... and having
FUN...weeeeeeeeeeeeeeeeeee
randumb thoughts of time and universe and skin.
OK this is first and foremost today:
http://www.ncbi.nlm.nih.gov/pubmed/22039501
Identification and characterisation of an iron-responsive candidate
probiotic.
[...] PMID: 22039501
so i save the BEST for LAST... or next to it or next to that.
And if i forget watch this carbon youtube... it's xlnt
carbon: modern marvels
http://www.youtube.com/watch?v=cfPjeMotfR8
<time 44:44> <views: 33,950>
But i already posted it twice but the post to Julie isn't coming up?
Yes it just did... so there...
Oh well... maybe the new google policy isn't working right?
Hey? I'll do a post on that?
OK...
-----------
Kewl action packed PURE ADRENALIN, youtube:
http://www.youtube.com/v/EEu42L0ufBY%26rel%3d0%26hl%3den_US%26feature%3dplayer_embedded%26version%3d3
It makes me think of that pig on the zip line...
Maxwell the Pig Returns! Zip-line Piggy - New GEICO Commercial
http://www.youtube.com/watch?v=6TlNOwwQQJk
First maxwell went wee wee wee all the way home and now he's zip
lining it..
He's an adrenalin junky for sure..
So are the guys on that kewl action packed youtube..<G>
==============
And before i do another THING:
One of the minor reasons i use longevinex.com resveratrol.
http://www.longevinex.com/articles/resveratrol-pill-manufacturer-posts-its-science-for-public-professional-examination/
Keeps your heart going?
But i like keeping crap outa my cells... stat to the eR (endoplasmic
reticulum)
25 hits: endoplasmic reticulum resveratrol-- pubmed
http://www.ncbi.nlm.nih.gov/pubmed?term=endoplasmic%20reticulum%20resveratrol
I can only wonder what happened when 122 year old Jeanne Calment drank
her glass of red wine PORT and consumed chocolates (one kilo a week)
and EVOO each day.
Was it the olive oil or chocolate or red wine that kept those ER's
going stat?
=============
mercola - non homeostatic iodine
http://articles.mercola.com/sites/articles/archive/2012/02/08/iodine-is-important-but-new-study-shows-too-much-causes-problems.aspx
Story at-a-glance
While there is evidence iodine levels are decreasing in the United
States, you need to be very careful about taking it in supplement
form, as this has been linked to health problems
Taking too much iodine has been linked to the development of
subclinical hypothyroidism, which may increase your risk of heart
problems
Toxin-free sea vegetables and spirulina are among the best natural
dietary sources of iodine
<snip>
Dr. David Brownstein on Iodine Part 1/3 <time: 11:27>
http://www.youtube.com/watch?feature=player_embedded&v=0-QCZAmXHqg&list=PL1639965B7883165C
http://www.youtube.com/watch?v=kUnxqpsdoJQ&feature=BFa&list=PL1639965B7883165C&lf=player_embedded
http://www.youtube.com/watch?v=nCZv8T7-xC8&feature=BFa&list=PL1639965B7883165C&lf=player_embedded
--------------
mercola -one flu over the...
http://articles.mercola.com/sites/articles/archive/2012/02/07/recommended-tamiflu-has-flawed-results.aspx
Story at-a-glance
The antiviral drug Tamiflu has been touted as effective in reducing
complications of flu such as bronchitis and pneumonia. Sales of the
drug skyrocketed during the hyped bird- and swine flu pandemics of
2006 and 2009. But some of the evidence supporting its use has turned
out to be based on fraudulent and/or missing data
Two employees of a communications company admitted they were paid to
ghostwrite studies where the conclusion specifically had to be in
support of Tamiflu’s effectiveness
Side effects of Tamiflu include convulsions, delirium and delusions.
The death of five Japanese children and seven adults has been linked
to the drug. Disturbingly, a 2009 study found more than half of all
children taking Tamiflu experience side effects, including
neuropsychological effects such as altered behavior and nightmares.
Other rare side effects such as toxic epidermal necrolysis and
blindness have also been reported
While antiviral drugs such as Tamiflu have been used with greater
frequency, the traditional first line of defense against the flu has
been vaccines. The evidence against flu vaccines is rapidly mounting
as well, and in recent years, a number of damaging studies published
in the medical literature, negating the claim that flu vaccine is the
best form of flu prevention
<snip>
-------------
mercola - GEE... no GMO, genetically modified organism & GE foods
http://articles.mercola.com/sites/articles/archive/2012/02/07/colorado-bans-gmo-crops.aspx
----------
http://articles.mercola.com/sites/articles/archive/2012/02/08/that-isnt-wax-on-your-organic-apple.aspx
Story at-a-glance
Most people are well aware that fresh conventionally-grown produce is
more or less contaminated with pesticides. Less known is the now-
common practice of coating fresh fruits and vegetables—including
organic varieties—with edible plastic coatings to increase shelf life
So-called modified atmosphere packaging (MAP) involves controlling or
modifying the atmosphere surrounding the product to slow spoilage.
This can be accomplished by coating the food with an edible film
Four basic materials used for edible films are lipids, resins,
polysaccharides and proteins, to which a variety of antimicrobials,
plasticizers and texturizers are added
These types of coatings present several potential health hazards, the
most severe of which is the potential to promote the growth of
foodborne pathogens if misapplied
<snip>
-------------
mercola - lyme disease - Dr. Dietrich Klinghardt
http://articles.mercola.com/sites/articles/archive/2012/02/05/dr-dietrich-klinghardt-on-lyme-disease.aspx
Dr. Mercola Interviews Dr. Dietrich Klinghardt about Lyme Disease
http://www.youtube.com/watch?feature=player_embedded&v=RkXqxRfG0jk
<time: 1:35:02> <views: 8,997>
Story at-a-glance
The increased virulence of Lyme disease is likely related to the
dramatic increase in electromagnetic fields and microwave radiation.
Therefore, EMF and microwave radiation mitigation are recommended as
part of the standard treatment protocol
Lyme disease is difficult to diagnose, particularly due to "the Lyme
paradox." In order to diagnose Lyme with one of the accepted
commercial tests, you must first treat it, in order for white blood
cells to mount an appropriate immune response. Only then can a lab
test detect the presence of Lyme disease
Dr. Klinghardt successfully uses ozone and a variety of novel
approaches to treat the simplest presentation of Lyme disease, the
orthopedic forms, which typically affect the larger joints
<snip>
-------------
mercola - broken heart blues and 21 Times increased risk due to same:
http://articles.mercola.com/sites/articles/archive/2012/02/03/how-grief-can-break-your-heart.aspx
Story at-a-glance
Losing a significant person in your life raises your risk of having a
heart attack the next day by 21 times, and in the following week by 6
times, new research shows
The abrupt increase in risk of cardiovascular events like heart attack
following extreme stress may be related to the flood of stress
hormones your body is exposed to
Stress cardiomyopathy, aka “broken heart syndrome,” which causes many
of the same symptoms as a heart attack, is also known to occur shortly
following extreme emotional stress
If you’re currently grieving or going through any type of emotional
stress, it’s important to take steps to support positive mental
health, not only for your mind but also for your body
<snip>
--------------
mercola - safe exercise
http://fitness.mercola.com/sites/fitness/archive/2012/02/03/weight-room-mistakes-that-lead-to-injury.aspx
Story at-a-glance
Four common mistakes that lead to injury are skipping your warm-up,
using poor form, putting too much stress on your shoulders, and
neglecting opposing muscle groups
A proper warm-up should raise your body temperature by one to two
degrees Celsius, or just below three degrees Fahrenheit. While most
opt to use aerobic activity for their warm-up, muscle-contracting
exercises are far more effective, as it only takes 10-15 seconds of
muscular contractions to raise your body temperature by 1ºC. Included
are 16 quick warm-up exercises that can speed up and improve your warm-
up routine
Super-slow weight training is a form of high-intensity exercise that
is not only more effective than conventional strength training, but
also much safer, as it actively prevents you from accidentally harming
your joints or suffering repetitive use injury. This makes it an ideal
form of exercise for virtually everyone, regardless of age or fitness
level
Proper recovery is also important, as exercising too vigorously too
frequently can stress your body and lead to injury
Women have reportedly started weight-training in record numbers, and
weight-training related injuries among women have subsequently
increased by 63 percent
<snip>
Dr. Mercola Interviews Doug McGuff about High Intensity Exercise
http://www.youtube.com/watch?feature=player_embedded&v=fQra-ME7vIo
<time: 2:06:27>
----------
mercola - krill oil
http://articles.mercola.com/sites/articles/archive/2012/02/06/without-krill-oil-your-brain-could-degenerate.aspx
Story at-a-glance
Omega-3 fat deficiency is a contributing factor to many neurological
and psychological problems, including degenerative disorders such as
“age-related” memory loss and Alzheimer’s
Sixty percent of your brain is fat. DHA alone makes up about 15
percent to 20 percent of your brain’s cerebral cortex, as well as 30
percent to 60 percent of your retina, making it an essential nutrient
for both brain- and eye health
It’s important to get the bulk of your omega-3 fat from animal-based
sources such as krill oil, because the DHA and EPA are far more
important for your health than the plant-based ALA. While ALA can
convert into DHA/EPA, this conversion is severely impaired when you
have elevated insulin levels, which affects over 80 percent of
Americans
In two different studies, taking 800-900 mg of DHA per day for 16-24
weeks resulted in significant improvements in memory, verbal fluency
scores, and rate of learning
<snip>
-------------
mercola - vitamin D3 to see (eye_
http://articles.mercola.com/sites/articles/archive/2012/02/06/this-vitamin-found-to-rejuvenate-aging-eyes.aspx
Story at-a-glance
After receiving a vitamin D3 supplement for just 6 weeks, mice had
improved vision and reductions in retinal inflammation and levels of
amyloid beta accumulation, which is a hallmark of aging
The findings suggest vitamin D3 may help prevent age-related macular
degeneration (AMD), which is the most common cause of blindness in the
elderly
Given that vitamin D affects the accumulation of amyloid beta in the
eyes, there is reason to believe it may do so in your brain and other
areas, potentially impacting diseases like Alzheimer’s and heart
disease
Safe sun exposure is the best way to optimize your vitamin D levels,
but a safe tanning bed, or a vitamin D3 supplement, can also be used
Other important nutrients for eye health include astaxanthin, lutein,
zeaxanthin, bilberry, black currant and omega-3 fats
<snip>
=================
Wellness Resources Newsletter - Be in the know with Byron J. Richards
http://www.wellnessresources.com/emails/news/2012/newsletter_020612.htm
Fish Oil Boosts Muscle Function in Response
to Exercise
A study shows that two grams of fish oil per day combined with
strength training exercise improved muscle strength better than
exercise alone. The study was conducted on 45 women aged 64 over a 90
day period. Read more >
http://www.wellnessresources.com/health/articles/fish_oil_boosts_muscle_function_in_response_to_exercise/
DHA is Essential for Male Fertility
Researchers have demonstrated for the first time that the omega-3
essential fatty acid DHA is required for the proper formation of
healthy sperm, thereby supporting male fertility. Read more >
http://www.wellnessresources.com/health/articles/dha_is_essential_for_male_fertility/
Omega-3 Fatty Acids Help Recovery from
Sciatic Nerve Injury
The discovery that omega-3 fatty acids DHA and EPA orchestrate the
inflammation repair process in nerve cells has led scientists to
conduct new types of nerve-related experiments. A new study shows that
DHA and EPA can help the sciatic nerve recover from injury. Read more
>
http://www.wellnessresources.com/health/articles/omega-3_fatty_acids_help_recovery_from_sciatic_nerve_injury/
Excess Omega 6 Intake Speeds Telomere Damage
and Aging
Will the real evil fat please stand up? A new study shows that eating
too much food of any type will shorten your telomeres and cause you to
have accelerated aging. However, the worst type of food appears to be
excess consumption of omega-6 fatty acids, not saturated fat
http://www.wellnessresources.com/health/articles/excess_omega_6_intake_speeds_telomere_damage_and_aging/
OK so read this telomere one... OK... will
-----------
http://www.life-enhancement.com/article_template.asp?id=710
Policosanol Improves Every Measure of Blood Cholesterol
This natural extract from sugar cane is better than prescription
drugs
By Will Block
What comes to mind when you think of Cuba? Beautiful island country,
great cigars, nice people, sexy music, great rum, Ernest Hemingway,
Guantanamo Bay, sugar cane, . . . OK, stop there. Sugar is something
we can all relate to, and the more intimately, the better. Sugar is
one of nature's most lavish gifts to mankind. Can you imagine a world
without sugar? Patrick Henry might as well have said, "Give me sugar,
or give me death!"
The sugar cane (Saccharum officinalis) is already such a splendid
jewel in Mother Nature's botanical crown, it's hard to imagine that it
could match itself in any way. But in a curious and surprising way, it
has. Like all plants, sugar cane is composed of countless different
kinds of chemical compounds, many of them still unidentified and many
surely having potential value to mankind in one way or another. In
that sense, every plant species on earth should be regarded as a
potential treasure chest of as yet undiscovered chemical or medicinal
riches, there to be discovered and used to our advantage.
One might think that the sugar-cane treasure chest had long since been
fully looted, so to speak, but new discoveries continue to be made.
One discovery, not many years ago, was of a substance found in sugar
cane called policosanol, which turns out to be remarkably effective
(and very safe) in treating one of the most prevalent and serious
health problems of modern society: high cholesterol. There's a nice
irony for you: sugar cane helps cause one medical problem (obesity)
but helps prevent another (atherosclerosis).
<snip>
I put the lime in the coconut or the molasses in the coffee?
Green TEA takes a back seat?
move on..dork
-----------
http://www.familypracticenews.com/news/more-top-news/single-view/distinguish-type-1-from-type-2-diabetes-in-obese-youth/ab5b3b8571.html
Distinguish Type 1 From Type 2 Diabetes in Obese Youth
By: BRUCE JANCIN, Family Practice News Digital Network
STEAMBOAT SPRINGS, COLO. – New-onset type 1 diabetes in an obese youth
cannot reliably be distinguished from pediatric type 2 diabetes on
clinical grounds in this era of epidemic obesity.
"The only way to distinguish obese type 1 diabetes from type 2
diabetes is to measure diabetes autoantibodies. And those autoantibody
panels are commercially available now. Signs and symptoms, diabetic
ketoacidosis, family history – they don’t really help you. We get an
autoantibody panel routinely in obese kids above age 10 presenting
with new-onset diabetes," said Dr. Charlotte M. Boney, chief of the
division of pediatric endocrinology and metabolism at Hasbro
Children’s Hospital in Providence, R.I.
Diabetic ketoacidosis is widely thought of as incompatible with type 2
diabetes. Not true. Close to 20% of youth with type 2 diabetes present
with DKA. Similarly, while a history of recent weight loss is
considered a classic presenting symptom of type 1 diabetes, it’s also
present in about one-quarter of young people presenting with type 2
diabetes, Dr. Boney noted.
The presence of pancreatic autoantibodies spells type 1 diabetes
metabolically, even if the patient appears phenotypically to have type
2 disease.
"Some pediatric endocrinologists call this ‘type one-and-a-half’
diabetes. No, no, no. Let’s not make things any weirder than they
already are. They have autoimmune diabetes, which is clearly type 1
diabetes. It just happens to be a little more complicated in them
because they also have the morbidity of obesity," she explained at the
meeting on practical pediatrics sponsored by the American Academy of
Pediatrics.
The obesity epidemic has muddied the diagnostic waters, because now
20%-30% of patients with new-onset type 1 diabetes are obese, as is a
similar proportion of the general pediatric population. At the same
time, the obesity epidemic has led to an increase in type 2 diabetes.
But it’s important to bear in mind that most youths with new-onset
diabetes still have type 1 disease, she said.
In the landmark prospective The SEARCH For Diabetes In Youth study,
nearly all children who presented under age 10 years had type 1
diabetes. Among 10- to 19-year-olds, the proportion with type 2
disease was 15% among whites, but considerably greater among racial
minorities: 58% among African Americans, 46% in Hispanics, 70% in
Asian/Pacific Islanders, and 86% among Native Americans (JAMA
2007;297:2716-24).
http://jama.ama-assn.org/content/297/24/2716.long
In the ongoing, multicenter, National Institutes of Health–sponsored
Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)
study, which enrolled 1,206 subjects with a presumptive diagnosis of
type 2 diabetes, 9.8% proved to be positive for GAD-65and/or
insulinoma-associated protein 2 autoantibodies. They had to be
excluded from participation in the treatment phase (Diabetes Care
2010;33:1970-5).
http://care.diabetesjournals.org/content/33/9/1970.long
As a practical approach to the initial therapy of young patients with
new-onset diabetes, Dr. Boney urged that those with DKA and ketosis
should be started on intravenous fluids and insulin, regardless of
their age and body habitus. If they are over age 10 and obese,
however, pancreatic autoimmunity should be ruled out before
transitioning to long-term therapy. For autoantibody-negative patients
whose clinical picture is consistent with type 2 diabetes, the
treatment is metformin, the only Food and Drug Administration–approved
therapy for children. Extensive experience shows that it’s a very safe
drug, she said.
The TODAY trial is designed to determine whether the best treatment
for type 2 diabetes in youth is metformin alone, metformin plus
rosiglitazone, or metformin and an intensive lifestyle intervention
aimed at achieving a 7%-10% weight loss.
The use of metformin to try to prevent diabetes in obese children with
insulin resistance and the metabolic syndrome is the subject of large
ongoing clinical trials. Until the results come in, Dr. Boney said she
sees no role for off-label prescribing of metformin, given that weight
loss and exercise are quite effective in improving insulin
sensitivity.
Maturity Onset Diabetes of the Young, or MODY, is worth considering in
white youth who are pancreatic autoantibody–negative and have a strong
history of parental non–type 1 diabetes. MODY is a single-gene
disorder that causes diabetes and is inherited from a parent.
"There are a lot of experts in the MODY field that think we’re grossly
underdiagnosing monogenic diabetes," said Dr. Boney.
The treatment for MODY is not insulin or metformin, but rather oral
sulfonylureas, although those agents are not FDA-approved for use in
children, she observed.
Dr. Boney reported having no financial conflicts.
<snip>
=============
Someone sent me this... and it was interesting to watch:
https://www.youtube.com/watch?v=AZU0c8DAIU4&feature=email
Mind blowing speech by Robert Welch in 1958 predicting Insiders plans
to destroy America
Proof that the NEW WORLD ORDER has been planned by the elite. Robert
Welch, Founder of The John Birch Society, predicted today's problems
with uncanny accuracy back in 1958 and prescribed solutions in 1974
that are very similar to Ron Paul's positions today. This is proof
that there are plans in place by the elite to systemically disassemble
US sovereignty. I wonder who those elite are.
<snip>
http://en.wikipedia.org/wiki/John_Birch_Society
http://en.wikipedia.org/wiki/John_Birch_Society#2009.E2.80.93present
The Society has been active in supporting the auditing[51] of, and
aims to eventually dismantle, the Federal Reserve System. The JBS
believes that the U.S. Constitution gave only Congress the ability to
coin money, and did not intend for it to delegate this power to a
banking monopoly, or to transform it into a fiat currency not backed
by gold or silver.
The JBS was a co-sponsor of the 2010 Conservative Political Action
Conference, ending its decades-long exile from the mainstream
conservative movement.
http://en.wikipedia.org/wiki/Federal_Reserve_System
http://en.wikipedia.org/wiki/Fiat_money
http://en.wikipedia.org/wiki/Conservative_Political_Action_Conference
I wonder if JBS supports
http://www.hillsdale.edu/news/imprimis/archive/issue.asp?year=2012&month=01
January 2012
Charles Murray
American Enterprise Institute
Do We Need the Department of Education?
<snip>
8 hits on a search of the JBS on hillsdale:
#1 of 8
http://www.hillsdale.edu/news/imprimis/archive/issue.asp?year=1980&month=06
June 1980
The News of Politics vs. The Politics of News
Lyn Nofziger
Not much in it or #2
http://www.hillsdale.edu/images/userImages/whadra/Page_7050/Steve%20Hayward.pdf
and the rest aren't related at all.
under
http://en.wikipedia.org/wiki/John_Birch_Society#Notable_members
I see the DUKE... last... JW..
==============
wonder how the duke would view this:
Benton Harbor, Michigan
Total population: 10826 (All urban)
Company town: Headquarters for WHIRLPOOL appliances
All Whirlpool factories in Benton Harbor have been shut down
and labor outsourced to other countries.
Whirlpool has received multi-million dollar grants from
the Federal government to help build employment in
Benton Harbor
2009: $19.3 million federal grant
2010: $20 million state grant
Whirlpool has not paid US income tax since 2008
Annual sales: $18 billion annual sales
% living in poverty: 90% ($10,000 per capita income)
% unemployed: 60%
% receiving food stamps: 99%
The video report: http://rt.com/news/whirlpool-neglect-outsourcing-benton-417/
<snip>
I haven't watched the dvd yet... but maybe when i read this?
==================
Bring Jobs Back To America By Hiring Chinese
http://abcnews.go.com/WNT/video/us-bridges-roads-built-chinese-firms-14594513?tab=9482930?ion=1206853&playlist=14594944
ABC shows obama saying let's build stuff... then chinese getting the
jobs and union
memebers pissed off. LOL
$9 billion in bridges being built by chinese... LOL
I guess the union workers priced themselves outa the market.... LOL
==================
SEE THE RED TYPE. Americans are going to pay unprecedented taxes so
the Federal Government can spend more to create more phony jobs and
raise the GDP with government-funded ventures. America is now a slave
state.
FEBRUARY 2, 2012
http://online.wsj.com/article/SB10001424052970204740904577195352148844134.html?mod=googlenews_wsj
$5 Trillion and Change
Obama's four years have seen the four highest deficits since 1946.
The political strategy behind Obamanomics was always simple: Call for
"stimulus" to rescue the economy, run up the debt with the biggest
spending blitz in 60 years, and then when the deficit explodes call
for higher taxes. The Congressional Budget Office annual review
released yesterday shows this is all on track.
CBO reports that annual spending over the Obama era has climbed to a
projected $3.6 trillion this fiscal year from $2.98 trillion in fiscal
2008, or more than 20%. The government spending burden has averaged
24% of GDP, up from an average of about 20%. This doesn't include the
$2 trillion tab for ObamaCare.
All of this has increased the federal debt by about $5 trillion in a
mere four years. Thanks to higher revenues, the federal deficit will
decline to $1.08 trillion in 2012, or 7% of GDP. But that is still the
highest deficit since 1946—except for the previous three years. In
other words, the four years of the Obama's Presidency will mark the
four highest years in spending and deficits as a share of the economy
since Harry Truman sat in the Oval Office.
We pause from this gloom for some good news: Despite the abuse they've
taken, House Republicans have made some fiscal progress. CBO estimates
that overall federal spending in 2012 will grow by only $3 billion, or
less than 1%, which compares with double digit increases during the
Obama-Pelosi years. Republicans have also tried to reform
entitlements, but Democrats wanted a $1 trillion tax hike ransom for
even modest cuts, which was wisely rejected.
The other part of the fiscal story is that revenues have been in the
tank for five years. In 2012 revenues will hit $2.52 trillion down
from $2.57 trillion in 2007. Revenues are still only 16.3% of GDP,
about two percentage points below the norm.
The drought has two main causes. First, the anemic recovery in jobs
and investment isn't spinning off enough new output (1.7% growth last
year) to boost tax receipts anywhere near their historic level.
Second, a series of non-stimulative tax cuts—tax rebates in 2008 and
2009, and payroll tax holidays in 2011 and this year—have depleted the
Treasury with little economic benefit. These tax cuts don't change the
incentive at the margin to work or invest, and they thus have little
feedback effect in revenues from faster growth.
The most amusing part of the CBO's report is its projection that the
deficit will fall to $269 billion by 2015, or a mere 1.5% of GDP, if
current law holds. But this is a fiscal fantasy because current law
never holds.
CBO predicts, for example, that all the Bush tax cuts will go away
next year. The Alternative Minimum Tax will supposedly be allowed to
hit 30 million tax filers (up from four million now) with an income as
low as $75,000 a year. Under those assumptions total federal revenues
rise by $1 trillion over the next three years, $1.5 trillion over five
years, and $3.6 trillion over 10 years. You can't get anywhere near
that level of revenues without a much bigger tax increase on the rich
and the middle class, or an extended boom in the range of 5% to 6%
annual growth.
Even the Keynesians who run CBO concede that the 2013 tax hike—on
capital gains, dividends, estates and small business—would knock
economic growth down to 1% next year and raise unemployment to 9.1%
(from 8.5%). That means about 750,000 more jobless Americans. You
can't have such a lousy economy and cut the deficit in half.
CBO also indulges in the fantasy that discretionary spending will fall
by nearly $2 trillion over the next decade—with almost all the cuts
after 2015. About $1.25 trillion of those cuts come from the automatic
across-the-board reductions that Congress and Mr. Obama agreed to last
year. But wait. More than half of those cuts will come from the
military budget and even Defense Secretary Leon Panetta has said these
reductions could be "devastating" to national security.
To sum it all up, CBO's facts plainly show that Mr. Obama has the
worst fiscal record of any President in modern times. No one else is
even close.
<snip>
====================
10,355 - hits: mucin cancer - pubmed
http://www.ncbi.nlm.nih.gov/pubmed?term=mucin%20cancer
1,656 hits: mucin muc1 cancer
http://www.ncbi.nlm.nih.gov/pubmed?term=mucin%20muc1%20cancer
1 hit: mucin muc1 cancer microbiota
http://www.ncbi.nlm.nih.gov/pubmed?term=mucin%20muc1%20cancer%20microbiota
#1 of 1
http://www.ncbi.nlm.nih.gov/pubmed/20703838
Curr Gastroenterol Rep. 2010 Oct;12(5):319-30.
Intestinal goblet cells and mucins in health and disease: recent
insights and progress.
Kim YS, Ho SB.
Source
Genemed Biotechnologies, 458 Carlton Court, South San Francisco, CA
94080, USA. youn...@ucsf.edu
Abstract
The mucus layer coating the gastrointestinal tract is the front line
of innate host defense, largely because of the secretory products of
intestinal goblet cells. Goblet cells synthesize secretory mucin
glycoproteins (MUC2) and bioactive molecules such as epithelial
membrane-bound mucins (MUC1, MUC3, MUC17), trefoil factor peptides
(TFF), resistin-like molecule beta (RELMbeta), and Fc-gamma binding
protein (Fcgbp). The MUC2 mucin protein forms trimers by disulfide
bonding in cysteine-rich amino terminal von Willebrand factor (vWF)
domains, coupled with crosslinking provided by TFF and Fcgbp proteins
with MUC2 vWF domains, resulting in a highly viscous extracellular
layer. Colonization by commensal intestinal microbiota is limited to
an outer "loose" mucus layer, and interacts with the diverse
oligosaccharides of mucin glycoproteins, whereas an "inner" adherent
mucus layer is largely devoid of bacteria. Defective mucus layers
resulting from lack of MUC2 mucin, mutated Muc2 mucin vWF domains, or
from deletion of core mucin glycosyltransferase enzymes in mice result
in increased bacterial adhesion to the surface epithelium, increased
intestinal permeability, and enhanced susceptibility to colitis caused
by dextran sodium sulfate. Changes in mucin gene expression and mucin
glycan structures occur in cancers of the intestine, contributing to
diverse biologic properties involved in the development and
progression of cancer. Further research is needed on identification
and functional significance of various components of mucus layers and
the complex interactions among mucus layers, microbiota, epithelial
cells, and the underlying innate and adaptive immunity. Further
elucidation of the regulatory mechanisms involved in mucin changes in
cancer and inflammation may lead to the development of novel
therapeutic approaches.
PMID: 20703838
Free PMC Article
http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20703838/?tool=pubmed
74 hits; mucin microbiota
http://www.ncbi.nlm.nih.gov/pubmed?term=mucin%20microbiota%20
57 hits : mucin - p ng
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=mucin&start=0&
13 0f 57 have: muc1 with mucin - p ng
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=mucin+muc1&start=0&
19 with muc1: p ng
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=+muc1&start=0&
Lactobacilli Bifidobacteria Streptococci - 28 hits: p ng
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=Lactobacilli+Bifidobacteria+Streptococci&start=0&
http://www.ncbi.nlm.nih.gov/pubmed/16973917
Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G315-22. Epub
2006 Sep 14.
The VSL#3 probiotic formula induces mucin gene expression and
secretion in colonic epithelial cells.
Caballero-Franco C, Keller K, De Simone C, Chadee K.
Source
Institute of Parasitology, McGill University, Saint Anne de Bellevue,
Quebec, Canada.
Abstract
Several studies have stressed the importance of the microbiota in the
maintenance of the gastrointestinal epithelium. Administration of
probiotic bacteria, supplements composed of microbiota constituents,
was previously shown to diminish symptoms in patients suffering from
inflammatory bowel diseases. This raises the possibility that
probiotics may play an active role in enhancing the intestinal barrier
at the mucosal surface. In this study, we investigated whether the
clinically tested VSL#3 probiotic formula and/or its secreted
components can augment the protective mucus layer in vivo and in
vitro. For in vivo studies, Wistar rats were orally administered the
probiotic mixture VSL#3 on a daily basis for seven days. After
treatment, basal luminal mucin content increased by 60%. In addition,
we exposed isolated rat colonic loops to the VSL#3 probiotic formula,
which significantly stimulated colonic mucin (MUC) secretion and MUC2
gene expression; however, MUC1 and MUC3 gene expression were only
slightly elevated. The effect of the VSL#3 mucin secretagogue was also
tested in vitro by use of LS 174T colonic epithelial cells. In
contrast to the animal studies, cultured cells incubated with VSL#3
bacteria did not exhibit increased mucin secretion. However, the
bacterial secreted products contained in the conditioned media
stimulated a remarkable mucin secretion effect. Among the three
bacterial groups (Lactobacilli, Bifidobacteria, and Streptococci)
contained in VSL#3, the Lactobacillus species were the strongest
potentiator of mucin secretion in vitro. A preliminary
characterization of the putative mucin secretagogue suggested that it
was a heat-resistant soluble compound, which is not sensitive to
protease and DNase treatment. These findings contribute to a better
understanding of the complex and beneficial interaction between
colonic epithelial cells and intestinal bacteria.
PMID: 16973917
Free full text
http://ajpgi.physiology.org/cgi/pmidlookup?view=long&pmid=16973917
We have seven hits in the p ng:
7 hits: VSL#3 probiotic formula
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=VSL%233&start=0&
VSL#3 - 125 hits - pubmed:
http://www.ncbi.nlm.nih.gov/pubmed?term=vsl%233
http://www.vsl3.com/
http://www.vsl3.com/about.asp
http://www.vsl3.com/research.asp
http://www.vsl3.com/uses-vsl.asp
Who Uses VSL#3®?
The probiotic medical food for the dietary management of Ulcerative
Colitis, Irritable Bowel Syndrome (IBS), or an Ileal Pouch
The human gastrointestinal (GI) system is populated by thousands of
billions of beneficial bacteria that act as a protective barrier
throughout the GI system. These bacteria perform a variety of
important biochemical functions from enhancing the protective
intestinal barrier to modulating intestinal inflammation and reducing
colonic permeability.
Under some conditions the number of pathogenic ("bad") bacteria in a
person’s intestines can begin to outnumber the good bacteria. Numerous
studies have implicated the overgrowth of pathogenic bacteria in
certain intestinal disorders.21,40 Studies have shown that patients
with ulcerative colitis (UC), irritable bowel syndrome (IBS), or an
ileal pouch tend to have a decreased concentration of beneficial
bacteria.4,14,52 This deficiency could lead to more flare-ups and
issues with diarrhea, frequency, and urgency.
VSL#3® is the only medical food that can restore beneficial intestinal
bacteria in UC, IBS and pouch patients with optimal quantities and
types of beneficial bacteria.
Ulcerative Colitis Patients – Several published studies have showed
that daily ingestion of VSL#3® can aid in the dietary management of
ulcerative colitis (UC).3,63,66
Patients with irritable bowel syndrome – Patients involved in two
double blind placebo-controlled trials reported satisfactory relief of
gas and bloating associated with IBS.33,68,69
Patients with an Ileal Pouch – VSL#3® has been recognized by the
American College of Gastroenterology Practice Parameter as a tool for
the dietary management of pouchitis. Three double-blind, placebo
controlled trials have shown that VSL#3® is important for the dietary
management of pouchitis. 19,20,44
Other Studies – Read other studies discussing the use of probiotics
and VSL#3® for the dietary management of serious intestinal disorders.
<snip>
#1 of 125 hits for VSL#3 on pubmed:
http://www.ncbi.nlm.nih.gov/pubmed/22247743
Probiotics Antimicrob Proteins. 2011 Mar;3(1):1-7.
Gut microbiota is not modified by Randomized, Double-blind, Placebo-
controlled Trial of VSL#3 in Diarrhea-predominant Irritable Bowel
Syndrome.
Michail S, Kenche H.
Abstract
Irritable Bowel Syndrome (IBS) is a common condition that negatively
impacts the quality of life for many individuals. The exact etiology
of this disorder is largely unknown; however, emerging studies suggest
that the gut microbiota is a contributing factor. Several clinical
trials show that probiotics, such as VSL#3, can have a favorable
effect on IBS. This double-blind, randomized placebo-controlled study
has been conducted in diarrhea-predominant IBS subjects in order to
investigate the effect of VSL#3 on the fecal microbiota. The bacterial
composition of the fecal microbiota was investigated using high-
throughput microarray technology to detect 16S RNA. Twenty four
subjects were randomized to receive VSL#3 or placebo for 8 weeks. IBS
symptoms were monitored using GSRS and quality of life questionnaires.
A favorable change in Satiety subscale was noted in the VSL #3 groups.
However, the consumption of the probiotic did not change the gut
microbiota. There were no adverse events or any safety concerns
encountered during this study. To summarize, the use of VSL#3 in this
pilot study was safe and showed improvement in specific GSRS-IBS
scores in diarrhea-predominant IBS subjects. The gut microbiota was
not affected by VSL#3 consumption suggesting that the mechanism of
action is not directly linked to the microbiota.
PMID: 22247743
Free PMC Article
http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22247743/?tool=pubmed
The --- alt.support.crohns-colitis group:
441 hits - vsl#3 - cc ng: (only 7 hits on p ng)
http://groups.google.com/group/alt.support.crohns-colitis/search?q=vsl%233&start=0&
chrono order (latest backwards) vsl#3
http://groups.google.com/group/alt.support.crohns-colitis/search?q=vsl%233&start=0&scoring=d&
http://www.eurekalert.org/pub_releases/2011-10/uob-cap101911.php
Could a probiotic be used to treat inflammatory bowel disease?
Scientists have been unclear for some time about how most probiotics
work. A new study has found a scientific 'design' for a probiotic
that
could be used to treat inflammatory bowel disease (IBD), such as
Crohn's disease.
The research by academics at the University of Bristol's School of
Veterinary Sciences and the School of Clinical Medicine is published
online in the journal PLoS ONE.
Most probiotics on the market, such as Lactobacillus and
Bifidobacterium, are lactic acid bacteria. Although probiotics have
been shown to successfully maintain remission in IBD, evidence of
their effectiveness in active disease is rare. The researchers have
found that this is because an increase in iron levels, which happens
during active IBD, inhibits the growth of probiotic bacteria,
including Lactobacillus.
Iron levels increase in the intestine during inflammation, bleeding,
during stress and when people are taking iron supplements. Iron is
critically important to the growth of most species of bacteria,
including pathogens, and its availability is what restricts their
growth. It is well known that pathogens increase growth rate by up to
8,000 times when exposed to increased levels of iron. Lactic acid
bacteria are unusual as they have evolved not to require iron, and so
do not increase growth rate when exposed to it.
Dr Tristan Cogan, Research Fellow in the School of Veterinary
Sciences, said: "When we started our study we considered the
properties that a probiotic would need to treat IBD. Most
importantly,
it would need to be able to survive and grow in the presence of high
levels of iron and to reduce inflammation. We then worked out how to
test bacteria to see whether it had these properties.
"The difficult step was finding a bacterium that had all of the
properties that we wanted. Now we have found something that looks
like
it should work, our next step will be to test the probiotic in
clinical trials."
The researchers found that a range of probiotic strains of lactic
acid
bacteria cannot respond to increased iron levels. The study then
identified a strain, which the academics have patented, that can and
showed that it has probiotic and immunomodulatory properties, and can
reduce pro-inflammatory responses to pathogens associated with IBD.
The researchers suggest that iron response is the factor that
prevents
probiotics from being useful in treating disease, and that their
bacterium could be a novel probiotic treatment for active intestinal
disease.
<snip>
Finding iron probiotic cogan?
OK. another october surprise... 2011 this time:
http://www.ncbi.nlm.nih.gov/pubmed/22039501
PLoS One. 2011;6(10):e26507. Epub 2011 Oct 19.
Identification and characterisation of an iron-responsive candidate
probiotic.
Bailey JR, Probert CS, Cogan TA.
Source
Mucosal Microbiology, School of Veterinary Sciences, University of
Bristol, Bristol, United Kingdom.
Abstract
BACKGROUND:
Iron is an essential cofactor in almost all biological systems. The
lactic acid bacteria (LAB), frequently employed as probiotics, are
unusual in having little or no requirement for iron. Iron in the human
body is sequestered by transferrins and lactoferrin, limiting
bacterial growth. An increase in the availability of iron in the
intestine by bleeding, surgery, or under stress leads to an increase
in the growth and virulence of many pathogens. Under these high iron
conditions, LAB are rapidly out-competed; for the levels of probiotic
bacteria to be maintained under high iron conditions they must be able
to respond by increasing growth rate to compete with the normal flora.
Despite this, iron-responsive genera are poorly characterised as
probiotics.
METHODOLOGY/PRINCIPAL FINDINGS:
Here, we show that a panel of probiotics are not able to respond to
increased iron availability, and identify an isolate of Streptococcus
thermophilus that can increase growth rate in response to increased
iron availability. The isolate of S. thermophilus selected was able to
reduce epithelial cell death as well as NF-κB signalling and IL-8
production triggered by pathogens. It was capable of crossing an
epithelial cell barrier in conjunction with E. coli and downregulating
Th1 and Th17 responses in primary human intestinal leukocytes.
CONCLUSIONS/SIGNIFICANCE:
We propose that an inability to compete with potential pathogens under
conditions of high iron availability such as stress and trauma may
contribute to the lack of efficacy of many LAB-based probiotics in
treating disease. Therefore, we offer an alternative paradigm which
considers that probiotics should be able to be competitive during
periods of intestinal bleeding, trauma or stress.
PMID: 22039501
Free PMC Article
http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22039501/?tool=pubmed
or
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0026507
18 hits: "Cogan TA"[Author]
http://www.ncbi.nlm.nih.gov/pubmed?term=%22Cogan%20TA%22%5BAuthor%5D
I guess cogan didn't know what met
http://www.aalatimes.com/2011/11/06/could-a-probiotic-be-used-to-treat-inflammatory-bowel-disease/
Could a probiotic be used to treat inflammatory bowel disease?
Sunday, November 6, 2011
<snip>
I guess Tristan doesn't have the strategy of nobel prize winner (1908)
of elie metchnikoff?
http://www.bris.ac.uk/vetscience/people/tristan-a-cogan/index.html
Tristan versus Eli?
http://en.wikipedia.org/wiki/%C3%89lie_Metchnikoff
What would elie metchnikoff do in this ironic situation?
Shall i ask?
But i already KNOW....so?
Iron versus lactic acid bacteria:
http://en.wikipedia.org/wiki/Lactic_acid
http://en.wikipedia.org/wiki/Lactic_acid_bacteria
95 hits: elie metchnikoff gut flora - all groups:
http://groups.google.com/groups/search?q=elie+metchnikoff+gut+flora&btnG=Search&sitesearch=
ONLY one of those is mine. LOL
http://groups.google.com/groups/search?q=elie+metchnikoff+gut+flora+randall&btnG=Search&sitesearch=
But there are two there:
http://groups.google.com/groups/search?q=+metchnikoff+psoriasis+randall&btnG=Search&sitesearch=
And one of them is a response from Russian and p ng friend:
Mikhail Inq:
http://groups.google.com/groups/profile?enc_user=6a3bFQ8AAAAqB9AcXjMSzBAJuMCsyIbP
Mikhail Inq also wrote a book (e book iirc) in this realm:
And that is a nick name:
27 hits for the nick name:
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=mikhail+Inq&start=0&
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/cc61052dc43999e8
mp2000:
My nickname is Mikhail Inq, I am russian, I live and work in Moscow.
Almost 40 years I have psoriasis.
I have 30-year's positive experience of a elimination diet and
cleansing methods.
As a consequence, my psoriasis is insignificant.
Now I have one-year positive experience of Pagano regimen
(cleansing,elimination diet, teas etc.).
In Russian Internet there is very few of information devoted to a
psoriasis.
In may 2000 I have based and I support a russian site "Psoriasis as
intestinal disease" - www.psora.df.ru.
On this site I have presented brief translation 5, 6 and 7 chapters,
and also some Appendixs from this book.
In Russia the treatment of a psoriasis of this method only starts.
The information and exchange of experience is extremely necessary
(not
only for Russians).
When you decide (may be after 2-3 months) that you have positive (or
negative) experience of application Pagano
regimen, please, fill special form www.psora.df.ru/form_qa_e.html (on
English - of course)
Your answer (on English) will be placed on "Exchange of
Experience" page www.psora.df.ru/eoe.html. Read this page.
The translation (on Russian) - on page www.psora.df.ru/que_ans.html
It will help to other with treatment from a psoriasis.
Best wishes for you.
<snip>
And none of his sites (above) open without a 404 error. Shucks..
And the only other hit i get is this one from the NPF forum from
LAZZA:
who said:
https://www.inspire.com/groups/talk-psoriasis/discussion/finding-the-way-to-heal-naturally/
[...] By Lazza
Reply 1994255
February 23, 2011 at 8:24 am
Report post
I have been doing a similar diet for the past 18 months with great
success (95% improvement in PPP symptoms). However it isn't exactly
the same. Despite what Pagano says I've had no issues with berries at
all. I also discovered potatoes are harmless to me. Dairy? Absolutely
poisonous. Gluten? Dunno, but I don't eat it any more. And so I
suggest expanding your horizons a bit. I've read the Pagano book and
found some of his suggestions to be strange and poorly explained,
albeit I do recommend his book overall.
While on Pagano, he is spot on wrt linking colon health with
psoriasis. I had irritable bowel syndrome for years and so I knew my
colon was messed up. Diet and probiotics cleared that up 90%. I also
took light doses of grapefruit seed extract and olive leaf extract to
kill off unwanted pathogens. However recently I changed this to simply
do a heavier dose of olive leaf extract, in response to a (suspected)
mild lung infection following a cold. Well it zapped whatever was
bothering my lungs, and I also noticed my psoriasis improving. Google
"olive leaf extract" and you will see that it is safe. At any rate,
keeping your colon flora healthy is important. In his thread and
research paper Mikhail Inq discusses the link between colon issues and
psoriasis. I am a true believer in it.
<snip>
OK, this one works:
http://www.psora.df.ru/que_ans_e.html
Are these all the same? Is roy cohen also Inq?
Duh, it says so... LoL
And these guys?
[...]Michael S., New York The author of a site has Dec 23, 2000
Mikhail Inq, Moscow, Russia inq-at-bmail.ru Dec 20, 2000
Roy Сohen, Сranbury, NJ USA roy-at-gghc.com Dec 15, 2000
Tim Nesielheum Nesielheum-at-aol.com Dec 30, 2000
Patsy snakeman-at-penn.com Jan 7,2001
Tom The author of a site has Mar 12, 2001
Lil Jen
<snip>
IIRC, tim N. has been on the p ng
Let's see: 315 times for
Tim Nesielheum (he's not a russian but did the pagano program i'm
guessing)
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/search?q=Tim+Nesielheum%09&start=0&
This one comes up as an oddity:
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/44d0a2e9dad3ec03
from marlon with subject matter:
attn: mikkel - very superb active newsgroups - ig dud vosfi - (1/1)
And all or mostly faked:
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/44d0a2e9dad3ec03?dmode=source
And not much happening at nuzer.net
ONly 487 hits for ALL groups:
nuzer.net
http://groups.google.com/groups/search?qt_s=1&q=nuzer.net+
One link for nuzer goes here:
VideoStash.Net is a video archive that updates often containing
amateur homemade sex and porn videos available for download.
OK back to Mikhail and 28 hits for him on ALL google groups:
http://groups.google.com/groups/search?hl=en&ie=UTF-8&q=mikhail+Inq+psoriasis&btnG=Search&sitesearch=
And his e-book
here:
http://www.psorias.info/
http://www.psorias.info/9785905504020_MPP_Part1_Systemic_psoriatic_process_eng.pdf
part II
http://www.psorias.info/9785905504044_MPP_Part2_Local_processes_eng.pdf
WELL.... Mikhail Peslyak has some really nice illustrations and
diagrams:
http://www.scribd.com/doc/25421572/Model-of-pathogenesis-of-psoriasis-Part-1-Systemic-psoriatic-process-Edition-e3-2-Mikhail-Peslyak
http://www.researchgate.net/topic/Models_of_pathogenesis_of_psoriasis/
I should have LOOKed at this thread first:
duh..
Tues, Feb 2 2010 9:13 am
Subject: Re: New e-book about pathogenesis of psoriasis
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/5106159adc141d94
Mikhail said:
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/1b62daa1078b874b
from
http://groups.google.com/groups/profile?hl=en&enc_user=6a3bFQ8AAAAqB9AcXjMSzBAJuMCsyIbP
==========
Biting the hand that nurtures YOU?
http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2012/01/29/BA9P1N089K.DTL&tsp=1
[...] Friends and relatives said Susan Poff and Robert Kamin of
Oakland were the perfect pair to adopt a foster child.
They had dedicated their careers to helping others escape poverty, she
as a physician assistant in a city-run clinic in the Tenderloin and he
as a clinical psychologist for inmates in the San Francisco County
Jail system.
But now, less than a decade after they adopted, their 15-year-old son
stands accused of strangling both Poff, 50, and Kamin, 55, then hiding
their bodies in the back of the family's PT Cruiser.
[...] Co-workers said Poff and Kamin were having some arguments with
their son, some of it having to do with him spending too much time in
the Occupy Oakland encampment, but nothing that sounded beyond the
scope of typical teenage rebelliousness.
<snip>
Occupy the toilet poisons this son's mind?
Seems likely.
http://occupywallst.org/
Do they even know they suck?
NOPE
http://occupywallst.org/about/
Principles of Solidarity
http://www.nycga.net/resources/principles-of-solidarity/
Statement of Autonomy
http://www.nycga.net/resources/statement-of-autonomy/
Declaration of the Occupation
http://www.nycga.net/resources/declaration/
Everyone has the Right to Occupy Space, Safely
http://occupywallst.org/article/everyone-has-right-occupy-space-safely/
As they support obama and he them then it's axiomatic
http://en.wikipedia.org/wiki/Occupy_Wall_Street
And now foster parents of a 15 year old occuparian have died.
LOOKs like a low IQ type:
http://i.dailymail.co.uk/i/pix/2012/01/31/article-0-118A13E0000005DC-441_306x423.jpg
See more pictures of the DEAD mother and home:
http://www.dailymail.co.uk/news/article-2094862/Moses-Kamin-15-murdered-parents-hid-bodies-car-argument-suspended-school.html
<snip>
It occupy worked to make the pie then let them eat their own pie.
But if they want YOUR pie via obamma as their momma....then
tell them to go BACK to the USSR boys...
As this 200 pound sucky foster brat, Moses Kamin is NOW living for
free the
rest of his sucky LIFE in public prisons paid for by FREE AMERICANS
http://sfist.com/2012/02/02/oakland_teen_arraigned_admitted_gui.php
If he was a muslim they'd chop his head off on friday afternoon the
market square.
Or they use to do that?
Don't see it here:
http://en.wikipedia.org/wiki/Sharia#Penalties
But that doesn't mean it doesn't happen.
This person witnessed a friday punishment:
http://www.tariqramadan.com/An-International-call-for,264.html?lang=fr
=====================
0 to 100 mph and back to 0 in less then five seconds?
No way...
check it out... on this carbon youtube:
http://www.psoriasis-healing.com/
<time: 44:44> <views: 33,950>
Carbon saves:
Katherine Legge crash Road America 2006
http://www.youtube.com/watch?v=ZCI-QSt0hpE
<time: 1:16> <48,645 views>
http://en.wikipedia.org/wiki/Katherine_Legge
Wow... carbon is amazing and it's global warming so
why don't we have nuclear power?
Because that Genie isn't safe and we're not transparent on this topic.
Why?
I don't know..
You would think the news pimps would be open and not closed like
bigots?
But their so bigotted on so many points.
ok.. move on dork dot.
==============
OK so my TIME is still timely.
via garrett lisi
http://www.cs.virginia.edu/~robins/A_Geometric_Theory_of_Everything.pdf
l
A Geometric Theory of Everything
by A. Garrett Lisi and James Owen Weatheral
<snip>
Nice kitty:
http://jamesowenweatherall.com/
co-author
http://uci.academia.edu/JamesWeatherall
<snip>
http://uci.academia.edu/JamesWeatherall/Papers/683487/On_the_Status_of_the_Geodesic_Principle_in_Newtonian_and_Relativistic_Physics
On the Status of the Geodesic Principle in Newtonian and Relativistic
Physics by James Owen Weatherall |
<snip>
Will they go TOE head once the LHC pumps out a higgs boson?
I guess.
http://www.scientificamerican.com/article.cfm?id=higgs-boson-signal-gains
Signal for Higgs Boson Particle Gains Strength
The latest analyses from the Large Hadron Collider boost the case for
the particle's existence, but there's no new data
By Geoff Brumfiel and Nature News Blog | February 7, 2012
Today the two main experiments at the Large Hadron Collider (LHC), the
world’s most powerful particle accelerator, submitted the results of
their latest analyses. The new papers boost the case for December’s
announcement of a possible Higgs signal, but let’s not get too
excited.
http://www.scientificamerican.com/topic.cfm?id=large-hadron-collider
https://cdsweb.cern.ch/collection/CMS%20Papers?ln=en
http://www.scientificamerican.com/article.cfm?id=higgs-lhc
First, there’s no new data in there—the LHC stopped colliding protons
back in November, and these latest results are just rehashes that
earlier run. In the case of the Compact Muon Solenoid (CMS),
physicists have been able to look at another possible kind of Higgs
decay, and that allows them to boost their Higgs signal from 2.5σ to
3.1σ. Taken together with data from the other detector, ATLAS, Higgs
overall signal now unofficially stands at about 4.3σ. In other words,
if statistics are to be believed, then this signal has about a 99.996
percent chance of being right.
It all sounds very convincing, but keep your hat on, because the fact
is that statistical coincidences happen every day. Over at Cosmic
Variance, Sean Carroll points out that there is a 3.8σ signal in the
Super Bowl coin toss. Does that mean that they’ve discovered a super-
partner to the bowl? No. (If you don’t get that joke, don’t worry, it
was written only as punishment for those who would).
http://blogs.discovermagazine.com/cosmicvariance/2012/02/04/a-3-8-sigma-anomaly/
After the LHC starts this spring, we’ll be much closer to knowing
what’s actually going on. Right now, scientists are meeting in
Chamonix, France to decide at what power to run the collider this
coming year. The latest rumours are that the machine will push from 7
to 8 TeV, and it will also increase its luminosity (the number of
collisions per pass).
http://indico.cern.ch/conferenceOtherViews.py?view=standard&confId=164089
For a little context more about what’s going on, check out this video
of my trip back in November:
<snip>
Hunting for the Higgs
http://www.youtube.com/watch?v=LXdrk6LC1eU&feature=player_embedded
<time: 2:54> <views: 9326>
randall... wow... really kewl stuff ... and having
FUN...weeeeeeeeeeeeeeeeeee
JRStern
Feb 9, 2012, 10:58:14 PM2/9/12
to
On Wed, 8 Feb 2012 10:53:45 -0800 (PST), randall <ranh...@aol.com>
wrote:
>hi
...
>
>http://www.longevinex.com/articles/resveratrol-pill-manufacturer-posts-its-science-for-public-professional-examination/
well OK, but those TJ's resvertrol pills are definitely doing
*something*, ... even when I've had them on the shelf to the
expiration date on the bottle.
J.
wrote:
>hi
...
>
>http://www.longevinex.com/articles/resveratrol-pill-manufacturer-posts-its-science-for-public-professional-examination/
well OK, but those TJ's resvertrol pills are definitely doing
*something*, ... even when I've had them on the shelf to the
expiration date on the bottle.
J.
randall
Feb 10, 2012, 2:38:12 PM2/10/12
to
On Feb 9, 7:58 pm, JRStern <JRSt...@foobar.invalid> wrote:
> On Wed, 8 Feb 2012 10:53:45 -0800 (PST), randall <ranhu...@aol.com>
> wrote:
>
>
>
> >hi
> ...
>
> >http://www.longevinex.com/articles/resveratrol-pill-manufacturer-post...
i feel your plaque.
Or i use to....
Not much these days..
Starting another trial..
But want to KILL myself via aspartame right now. LoL
I know... it's a trial... i do for MANkind.
Always testing that Gi TRACT.
And permeability.
So we plug those leaky holes and stop Th17 production
and....
What does resveratrol have to do with it?
It inhibits pde4 like apremilast to be exact. <G>
So i'll do my next thread on it...
right NOW..
and then i'll clean up so other things on my mind.
randall
ps- use www.longevinex.com... cost more but worth it..duh..
> On Wed, 8 Feb 2012 10:53:45 -0800 (PST), randall <ranhu...@aol.com>
> wrote:
>
>
>
> >hi
> ...
>
> >http://www.longevinex.com/articles/resveratrol-pill-manufacturer-post...
>
> well OK, but those TJ's resvertrol pills are definitely doing
> *something*, ... even when I've had them on the shelf to the
> expiration date on the bottle.
>
> J.
j
> well OK, but those TJ's resvertrol pills are definitely doing
> *something*, ... even when I've had them on the shelf to the
> expiration date on the bottle.
>
> J.
i feel your plaque.
Or i use to....
Not much these days..
Starting another trial..
But want to KILL myself via aspartame right now. LoL
I know... it's a trial... i do for MANkind.
Always testing that Gi TRACT.
And permeability.
So we plug those leaky holes and stop Th17 production
and....
What does resveratrol have to do with it?
It inhibits pde4 like apremilast to be exact. <G>
So i'll do my next thread on it...
right NOW..
and then i'll clean up so other things on my mind.
randall
ps- use www.longevinex.com... cost more but worth it..duh..
JRStern
Feb 10, 2012, 4:47:06 PM2/10/12
to
On Fri, 10 Feb 2012 11:38:12 -0800 (PST), randall <ranh...@aol.com>
wrote:
>So we plug those leaky holes and stop Th17 production
>and....
>
>What does resveratrol have to do with it?
>
>It inhibits pde4 like apremilast to be exact. <G>
>
>So i'll do my next thread on it...
>
>right NOW..
OK I scanned your next thread, but don't see any dosage indications.
At modest doses of resveratrol, I've seen zip effects on p.
TJ's brand, says "125mg of trans".
J.
was:
Re: FUN stuff --> Longevinex - (10) Mercola - Byron -Ai-> Diabetes -
JBS look back -->JW (The Duke) --Charles Murray-->Imprimis --Jobs down
the Whirlpool? --Hire Chinese? -- Mucin & Cancer --VSL#3 - Cogan -INQ
-> Pagano -TIME -Higgs Boson
wrote:
>So we plug those leaky holes and stop Th17 production
>and....
>
>What does resveratrol have to do with it?
>
>It inhibits pde4 like apremilast to be exact. <G>
>
>So i'll do my next thread on it...
>
>right NOW..
At modest doses of resveratrol, I've seen zip effects on p.
TJ's brand, says "125mg of trans".
J.
was:
Re: FUN stuff --> Longevinex - (10) Mercola - Byron -Ai-> Diabetes -
JBS look back -->JW (The Duke) --Charles Murray-->Imprimis --Jobs down
the Whirlpool? --Hire Chinese? -- Mucin & Cancer --VSL#3 - Cogan -INQ
-> Pagano -TIME -Higgs Boson
randall
Feb 10, 2012, 5:19:32 PM2/10/12
to
On Feb 10, 1:47 pm, JRStern <JRSt...@foobar.invalid> wrote:
> On Fri, 10 Feb 2012 11:38:12 -0800 (PST), randall <ranhu...@aol.com>
J
Why don't you simply BUY the www.longevinex.com brand?
You get what you pay for.
A GOOD product individually shrink wrapped to avoid
oxygen exposure which deGRADes resveratrol btw.
If not, then why bother?
But the 3/4 bottle of red wine (cab or ?? whichever red wine)
and drink some.
But i'm doing really really WELL with longevinex.com
I love the stuff.
And will continue to use one tab a day.
And since it might add YEARs of CLEAR skin to your life
what is that worth to you?
Enbrel is like #12,000 a year?
LOL
And this can be had for
what?
OK i'd buy it by the dozen as it's cheaper.
http://store.longevinex.com/shared/StoreFront/default.asp?CS=longevinex&StoreType=BtoC&Count1=649425685&Count2=566566109
And i just posted my next post on oldster
Bernando LaPallo.
here
Fri, Feb 10 2012 2:07 pm
Subject: 111 Year Old Bernando LaPallo --(diet + more tips) -- Epstein-
Barr Virus & Psor? - ERAP1 (ARTS-1) --> EBV &Vitamin D3 ->RecePtors --
CFS -> mAbs and Apremilast ++++
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/12b28b1e14ac547e
Like 10 minutes ago...
As in that commercial with the guy saying in mandarin da shula boola
or 37 seconds ago.. LOL
And this is huge:'
And my post on it is HUGE-erest.
http://www.ncbi.nlm.nih.gov/pubmed/22304913
Cell. 2012 Feb 3;148(3):421-33.
Resveratrol ameliorates aging-related metabolic phenotypes by
inhibiting cAMP phosphodiesterases.
Park SJ, Ahmad F, Philp A, Baar K, Williams T, Luo H, Ke H, Rehmann H,
Taussig R, Brown AL, Kim MK, Beaven MA, Burgin AB, Manganiello V,
Chung JH.
Source
Laboratory of Obesity and Aging Research, Genetics and Developmental
Biology Center, National Heart Lung and Blood Institute, National
Institutes of Health, Bethesda, MD 20892, USA.
Abstract
Resveratrol, a polyphenol in red wine, has been reported as a calorie
restriction mimetic with potential antiaging and antidiabetogenic
properties. It is widely consumed as a nutritional supplement, but its
mechanism of action remains a mystery. Here, we report that the
metabolic effects of resveratrol result from competitive inhibition of
cAMP-degrading phosphodiesterases, leading to elevated cAMP levels.
The resulting activation of Epac1, a cAMP effector protein, increases
intracellular Ca(2+) levels and activates the CamKKβ-AMPK pathway via
phospholipase C and the ryanodine receptor Ca(2+)-release channel. As
a consequence, resveratrol increases NAD(+) and the activity of Sirt1.
Inhibiting PDE4 with rolipram reproduces all of the metabolic benefits
of resveratrol, including prevention of diet-induced obesity and an
increase in mitochondrial function, physical stamina, and glucose
tolerance in mice. Therefore, administration of PDE4 inhibitors may
also protect against and ameliorate the symptoms of metabolic diseases
associated with aging.
PMID: 22304913
And only a few days ago i did the cAMP and cGMP deal and getting
the polyamines outa your BOX... body...
SO have some or take some TIME to find the BEST and
marry it and live haPPiLLy ever after..
Then come down to SD and let me see YOU... LOL
randall... what i do for psoriatics that i would also do for the WHOLE
world? lol
> On Fri, 10 Feb 2012 11:38:12 -0800 (PST), randall <ranhu...@aol.com>
Why don't you simply BUY the www.longevinex.com brand?
You get what you pay for.
A GOOD product individually shrink wrapped to avoid
oxygen exposure which deGRADes resveratrol btw.
If not, then why bother?
But the 3/4 bottle of red wine (cab or ?? whichever red wine)
and drink some.
But i'm doing really really WELL with longevinex.com
I love the stuff.
And will continue to use one tab a day.
And since it might add YEARs of CLEAR skin to your life
what is that worth to you?
Enbrel is like #12,000 a year?
LOL
And this can be had for
what?
OK i'd buy it by the dozen as it's cheaper.
http://store.longevinex.com/shared/StoreFront/default.asp?CS=longevinex&StoreType=BtoC&Count1=649425685&Count2=566566109
And i just posted my next post on oldster
Bernando LaPallo.
here
Fri, Feb 10 2012 2:07 pm
Subject: 111 Year Old Bernando LaPallo --(diet + more tips) -- Epstein-
Barr Virus & Psor? - ERAP1 (ARTS-1) --> EBV &Vitamin D3 ->RecePtors --
CFS -> mAbs and Apremilast ++++
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/12b28b1e14ac547e
Like 10 minutes ago...
As in that commercial with the guy saying in mandarin da shula boola
or 37 seconds ago.. LOL
And this is huge:'
And my post on it is HUGE-erest.
http://www.ncbi.nlm.nih.gov/pubmed/22304913
Cell. 2012 Feb 3;148(3):421-33.
Resveratrol ameliorates aging-related metabolic phenotypes by
inhibiting cAMP phosphodiesterases.
Park SJ, Ahmad F, Philp A, Baar K, Williams T, Luo H, Ke H, Rehmann H,
Taussig R, Brown AL, Kim MK, Beaven MA, Burgin AB, Manganiello V,
Chung JH.
Source
Laboratory of Obesity and Aging Research, Genetics and Developmental
Biology Center, National Heart Lung and Blood Institute, National
Institutes of Health, Bethesda, MD 20892, USA.
Abstract
Resveratrol, a polyphenol in red wine, has been reported as a calorie
restriction mimetic with potential antiaging and antidiabetogenic
properties. It is widely consumed as a nutritional supplement, but its
mechanism of action remains a mystery. Here, we report that the
metabolic effects of resveratrol result from competitive inhibition of
cAMP-degrading phosphodiesterases, leading to elevated cAMP levels.
The resulting activation of Epac1, a cAMP effector protein, increases
intracellular Ca(2+) levels and activates the CamKKβ-AMPK pathway via
phospholipase C and the ryanodine receptor Ca(2+)-release channel. As
a consequence, resveratrol increases NAD(+) and the activity of Sirt1.
Inhibiting PDE4 with rolipram reproduces all of the metabolic benefits
of resveratrol, including prevention of diet-induced obesity and an
increase in mitochondrial function, physical stamina, and glucose
tolerance in mice. Therefore, administration of PDE4 inhibitors may
also protect against and ameliorate the symptoms of metabolic diseases
associated with aging.
PMID: 22304913
And only a few days ago i did the cAMP and cGMP deal and getting
the polyamines outa your BOX... body...
SO have some or take some TIME to find the BEST and
marry it and live haPPiLLy ever after..
Then come down to SD and let me see YOU... LOL
randall... what i do for psoriatics that i would also do for the WHOLE
world? lol
JRStern
Feb 10, 2012, 6:05:09 PM2/10/12
to
On Fri, 10 Feb 2012 14:19:32 -0800 (PST), randall <ranh...@aol.com>
wrote:
>On Feb 10, 1:47 pm, JRStern <JRSt...@foobar.invalid> wrote:
>> On Fri, 10 Feb 2012 11:38:12 -0800 (PST), randall <ranhu...@aol.com>
>> wrote:
>>
>> >So we plug those leaky holes and stop Th17 production
>> >and....
>>
>> >What does resveratrol have to do with it?
>>
>> >It inhibits pde4 like apremilast to be exact. <G>
>>
>> >So i'll do my next thread on it...
>>
>> >right NOW..
>>
>> OK I scanned your next thread, but don't see any dosage indications.
>>
>> At modest doses of resveratrol, I've seen zip effects on p.
>>
>> TJ's brand, says "125mg of trans".
>>
>> J.
>>
>
>
capsule.
>Abstract
>Resveratrol, a polyphenol in red wine, has been reported as a calorie
>restriction mimetic with potential antiaging and antidiabetogenic
>properties. It is widely consumed as a nutritional supplement, but its
>mechanism of action remains a mystery. Here, we report that the
>metabolic effects of resveratrol result from competitive inhibition of
>cAMP-degrading phosphodiesterases, leading to elevated cAMP levels.
>The resulting activation of Epac1, a cAMP effector protein, increases
>intracellular Ca(2+) levels and activates the CamKK?-AMPK pathway via
did not seem to get the rush from eating some hard candy, that I might
have expected.
I wonder what the half-life is for resveratrol, I suspect it's
somewhat long, on the order of days. Half-life of curumin seems much
shorter.
So maybe daily reseveratrol for weeks builds up. I've only tried it
for a few days at a time, so far.
J.
wrote:
>On Feb 10, 1:47 pm, JRStern <JRSt...@foobar.invalid> wrote:
>> On Fri, 10 Feb 2012 11:38:12 -0800 (PST), randall <ranhu...@aol.com>
>> wrote:
>>
>> >So we plug those leaky holes and stop Th17 production
>> >and....
>>
>> >What does resveratrol have to do with it?
>>
>> >It inhibits pde4 like apremilast to be exact. <G>
>>
>> >So i'll do my next thread on it...
>>
>> >right NOW..
>>
>> OK I scanned your next thread, but don't see any dosage indications.
>>
>> At modest doses of resveratrol, I've seen zip effects on p.
>>
>> TJ's brand, says "125mg of trans".
>>
>> J.
>>
>
>
>But i'm doing really really WELL with longevinex.com
>
>I love the stuff.
>
>And will continue to use one tab a day.
>
>And since it might add YEARs of CLEAR skin to your life
>what is that worth to you?
>
>Enbrel is like #12,000 a year?
>
>LOL
>
>And this can be had for
>
>what?
>
>OK i'd buy it by the dozen as it's cheaper.
>
>http://store.longevinex.com/shared/StoreFront/default.asp?CS=longevinex&StoreType=BtoC&Count1=649425685&Count2=566566109
MUCH cheaper at TJ's, and the Longevinex has only 100mg of trans per
>
>I love the stuff.
>
>And will continue to use one tab a day.
>
>And since it might add YEARs of CLEAR skin to your life
>what is that worth to you?
>
>Enbrel is like #12,000 a year?
>
>LOL
>
>And this can be had for
>
>what?
>
>OK i'd buy it by the dozen as it's cheaper.
>
>http://store.longevinex.com/shared/StoreFront/default.asp?CS=longevinex&StoreType=BtoC&Count1=649425685&Count2=566566109
capsule.
>Abstract
>Resveratrol, a polyphenol in red wine, has been reported as a calorie
>restriction mimetic with potential antiaging and antidiabetogenic
>properties. It is widely consumed as a nutritional supplement, but its
>mechanism of action remains a mystery. Here, we report that the
>metabolic effects of resveratrol result from competitive inhibition of
>cAMP-degrading phosphodiesterases, leading to elevated cAMP levels.
>The resulting activation of Epac1, a cAMP effector protein, increases
>phospholipase C and the ryanodine receptor Ca(2+)-release channel. As
>a consequence, resveratrol increases NAD(+) and the activity of Sirt1.
>Inhibiting PDE4 with rolipram reproduces all of the metabolic benefits
>of resveratrol, including prevention of diet-induced obesity and an
>increase in mitochondrial function, physical stamina, and glucose
>tolerance in mice.
Glucose tolerance? That is something that I have perhaps observed,
>a consequence, resveratrol increases NAD(+) and the activity of Sirt1.
>Inhibiting PDE4 with rolipram reproduces all of the metabolic benefits
>of resveratrol, including prevention of diet-induced obesity and an
>increase in mitochondrial function, physical stamina, and glucose
>tolerance in mice.
did not seem to get the rush from eating some hard candy, that I might
have expected.
I wonder what the half-life is for resveratrol, I suspect it's
somewhat long, on the order of days. Half-life of curumin seems much
shorter.
So maybe daily reseveratrol for weeks builds up. I've only tried it
for a few days at a time, so far.
J.
randall
Feb 10, 2012, 6:19:06 PM2/10/12
to
On Feb 10, 3:05 pm, JRStern <JRSt...@foobar.invalid> wrote:
> On Fri, 10 Feb 2012 14:19:32 -0800 (PST), randall <ranhu...@aol.com>
j
It's like hours iirc.
I can pubmed that.
OK will do it.
done it..
21 hits -
http://www.ncbi.nlm.nih.gov/pubmed?term=Resveratrol%20half%20life
#3 of 21 is first i opened...
and it says..
3 to 5 hours...
http://www.ncbi.nlm.nih.gov/pubmed/21520090
J Pharm Sci. 2011 Apr 24. doi: 10.1002/jps.22588.
Preclinical pharmacokinetic evaluation of resveratrol trimethyl ether
in sprague-dawley rats: the impacts of aqueous solubility, dose
escalation, food and repeated dosing on oral bioavailability.
Lin HS, Ho PC.
Source
Department of Pharmacy, National University of Singapore, 10 Kent
Ridge Crescent, Singapore 119260. ph...@nus.edu.sg.
Abstract
Resveratrol trimethyl ether (trans-3,5,4'-trimethoxystilbene, RTE) is
a naturally occurring and pharmacologically active resveratrol
derivative. To evaluate its suitability as a drug candidate, a
pharmacokinetic study was carried out in Sprague-Dawley rats with the
emphasis to identify the impact of aqueous solubility, dose
escalation, food, and repeated dosing on its oral bioavailability.
Upon single intravenous administration (5 mg/kg), RTE displayed
moderate clearance (35.5 ± 5.3 mL/min/kg) and a fairly long terminal
elimination half-life (511 ± 136 min); dose escalation (5-20 mg/kg)
did not cause nonlinear pharmacokinetics. When given orally in
suspension (60 mg/kg), RTE was poorly absorbed with negligible
bioavailability (< 1.5%), fasting further decreased its
bioavailability (<1%). However, when administered in a solution
formulated with randomly methylated-β-cyclodextrin (15 mg/kg), RTE was
rapidly absorbed with good bioavailability (46.5 ± 4.8%). Dose
escalation resulted in increased bioavailability (64.6 ± 8.0%) at the
dose of 60 mg/kg. Repeated RTE dosing (7 daily oral doses) did not
alter the clearance, terminal elimination half-life and
bioavailability. In summary, the aqueous solubility of RTE was a
barrier to oral absorption; repeated RTE administrations did not alter
its pharmacokinetic profiles; as RTE possessed appropriate
pharmacokinetic profiles, further investigation on RTE as a drug
candidate is warranted. © 2011 Wiley-Liss, Inc. and the American
Pharmacists Association J Pharm Sci.
PMID: 21520090
But what is the half life of apremilast?
nope... zero returns
http://www.ncbi.nlm.nih.gov/pubmed?term=apremilast%20half-life
What matters is like with a drop of alcohol and those c. elegan worms
in my mind...
If a drop is enough to double or add years to life.
Then tell us the genetics.
And we NOW have genetics of resveratrol and who knew it would be
pde4?
They all figured it was sirtI which isn't OFF the TABLE btw.
So blowing NIH $$$ on this stuff adds UP in the LONG run..
And when they HIT a HOME RUN it's FUN and add years to YOUR GAME.
...
So if MY HaLF LIFE is increased by longevinex resveratrol then
why worry about it's HALF LIFE?
iirc bill sardi has the half life of his products on his site?
But i'm doing another thread RIGHT now..
so i'm gonna finish it..
I said FINNISH... LOL
Those Fins...eat fish...
http://en.wikipedia.org/wiki/Finland
4.5 million people about HALF of LA where you live are in
FINLAND...which means OUR LAND.
I wonder how their half life adds up in comparison to YOURs?
Just a thought..
randall... a full life... around 111 to 122 1/2 sounds nice to me...
> On Fri, 10 Feb 2012 14:19:32 -0800 (PST), randall <ranhu...@aol.com>
> wrote:
>
>
>
>
>
>
>
>
>
> >On Feb 10, 1:47 pm, JRStern <JRSt...@foobar.invalid> wrote:
> >> On Fri, 10 Feb 2012 11:38:12 -0800 (PST), randall <ranhu...@aol.com>
> >> wrote:
>
> >> >So we plug those leaky holes and stop Th17 production
> >> >and....
>
> >> >What does resveratrol have to do with it?
>
> >> >It inhibits pde4 like apremilast to be exact. <G>
>
> >> >So i'll do my next thread on it...
>
> >> >right NOW..
>
> >> OK I scanned your next thread, but don't see any dosage indications.
>
> >> At modest doses of resveratrol, I've seen zip effects on p.
>
> >> TJ's brand, says "125mg of trans".
>
> >> J.
>
> >But i'm doing really really WELL with longevinex.com
>
> >I love the stuff.
>
> >And will continue to use one tab a day.
>
> >And since it might add YEARs of CLEAR skin to your life
> >what is that worth to you?
>
> >Enbrel is like #12,000 a year?
>
> >LOL
>
> >And this can be had for
>
> >what?
>
> >OK i'd buy it by the dozen as it's cheaper.
>
> >http://store.longevinex.com/shared/StoreFront/default.asp?CS=longevin...
>
>
>
>
>
>
>
>
>
> >On Feb 10, 1:47 pm, JRStern <JRSt...@foobar.invalid> wrote:
> >> On Fri, 10 Feb 2012 11:38:12 -0800 (PST), randall <ranhu...@aol.com>
> >> wrote:
>
> >> >So we plug those leaky holes and stop Th17 production
> >> >and....
>
> >> >What does resveratrol have to do with it?
>
> >> >It inhibits pde4 like apremilast to be exact. <G>
>
> >> >So i'll do my next thread on it...
>
> >> >right NOW..
>
> >> OK I scanned your next thread, but don't see any dosage indications.
>
> >> At modest doses of resveratrol, I've seen zip effects on p.
>
> >> TJ's brand, says "125mg of trans".
>
> >> J.
>
> >But i'm doing really really WELL with longevinex.com
>
> >I love the stuff.
>
> >And will continue to use one tab a day.
>
> >And since it might add YEARs of CLEAR skin to your life
> >what is that worth to you?
>
> >Enbrel is like #12,000 a year?
>
> >LOL
>
> >And this can be had for
>
> >what?
>
> >OK i'd buy it by the dozen as it's cheaper.
>
It's like hours iirc.
I can pubmed that.
OK will do it.
done it..
21 hits -
http://www.ncbi.nlm.nih.gov/pubmed?term=Resveratrol%20half%20life
#3 of 21 is first i opened...
and it says..
3 to 5 hours...
http://www.ncbi.nlm.nih.gov/pubmed/21520090
J Pharm Sci. 2011 Apr 24. doi: 10.1002/jps.22588.
Preclinical pharmacokinetic evaluation of resveratrol trimethyl ether
in sprague-dawley rats: the impacts of aqueous solubility, dose
escalation, food and repeated dosing on oral bioavailability.
Lin HS, Ho PC.
Source
Department of Pharmacy, National University of Singapore, 10 Kent
Ridge Crescent, Singapore 119260. ph...@nus.edu.sg.
Abstract
Resveratrol trimethyl ether (trans-3,5,4'-trimethoxystilbene, RTE) is
a naturally occurring and pharmacologically active resveratrol
derivative. To evaluate its suitability as a drug candidate, a
pharmacokinetic study was carried out in Sprague-Dawley rats with the
emphasis to identify the impact of aqueous solubility, dose
escalation, food, and repeated dosing on its oral bioavailability.
Upon single intravenous administration (5 mg/kg), RTE displayed
moderate clearance (35.5 ± 5.3 mL/min/kg) and a fairly long terminal
elimination half-life (511 ± 136 min); dose escalation (5-20 mg/kg)
did not cause nonlinear pharmacokinetics. When given orally in
suspension (60 mg/kg), RTE was poorly absorbed with negligible
bioavailability (< 1.5%), fasting further decreased its
bioavailability (<1%). However, when administered in a solution
formulated with randomly methylated-β-cyclodextrin (15 mg/kg), RTE was
rapidly absorbed with good bioavailability (46.5 ± 4.8%). Dose
escalation resulted in increased bioavailability (64.6 ± 8.0%) at the
dose of 60 mg/kg. Repeated RTE dosing (7 daily oral doses) did not
alter the clearance, terminal elimination half-life and
bioavailability. In summary, the aqueous solubility of RTE was a
barrier to oral absorption; repeated RTE administrations did not alter
its pharmacokinetic profiles; as RTE possessed appropriate
pharmacokinetic profiles, further investigation on RTE as a drug
candidate is warranted. © 2011 Wiley-Liss, Inc. and the American
Pharmacists Association J Pharm Sci.
PMID: 21520090
But what is the half life of apremilast?
nope... zero returns
http://www.ncbi.nlm.nih.gov/pubmed?term=apremilast%20half-life
What matters is like with a drop of alcohol and those c. elegan worms
in my mind...
If a drop is enough to double or add years to life.
Then tell us the genetics.
And we NOW have genetics of resveratrol and who knew it would be
pde4?
They all figured it was sirtI which isn't OFF the TABLE btw.
So blowing NIH $$$ on this stuff adds UP in the LONG run..
And when they HIT a HOME RUN it's FUN and add years to YOUR GAME.
...
So if MY HaLF LIFE is increased by longevinex resveratrol then
why worry about it's HALF LIFE?
iirc bill sardi has the half life of his products on his site?
But i'm doing another thread RIGHT now..
so i'm gonna finish it..
I said FINNISH... LOL
Those Fins...eat fish...
http://en.wikipedia.org/wiki/Finland
4.5 million people about HALF of LA where you live are in
FINLAND...which means OUR LAND.
I wonder how their half life adds up in comparison to YOURs?
Just a thought..
randall... a full life... around 111 to 122 1/2 sounds nice to me...
JRStern
Feb 11, 2012, 2:18:41 PM2/11/12
to
On Fri, 10 Feb 2012 15:19:06 -0800 (PST), randall <ranh...@aol.com>
wrote:
>moderate clearance (35.5 ą 5.3 mL/min/kg) and a fairly long terminal
>elimination half-life (511 ą 136 min); dose escalation (5-20 mg/kg)
Doesn't that say 511 minutes, aka 8+ hours?
But it may leave behind changes that last longer, if it works by
binding to something that takes days to replenish.
>But what is the half life of apremilast?
http://www.google.com/search?q=apremilast+half-life&sourceid=ie7&rls=com.microsoft:en-us:IE-SearchBox&ie=&oe=
Looks also like about 8 hours.
J.
wrote:
>elimination half-life (511 ą 136 min); dose escalation (5-20 mg/kg)
Doesn't that say 511 minutes, aka 8+ hours?
But it may leave behind changes that last longer, if it works by
binding to something that takes days to replenish.
>But what is the half life of apremilast?
Looks also like about 8 hours.
J.
randall
Feb 11, 2012, 5:26:11 PM2/11/12
to
On Feb 11, 11:18 am, JRStern <JRSt...@foobar.invalid> wrote:
> On Fri, 10 Feb 2012 15:19:06 -0800 (PST), randall <ranhu...@aol.com>
> >moderate clearance (35.5 ± 5.3 mL/min/kg) and a fairly long terminal
> >elimination half-life (511 ± 136 min); dose escalation (5-20 mg/kg)
You are correct.
8.51666666666666666666666666666666666666 hours to be.....
Anyway that goes to show.
It must not help my plain old brain calculator. LOL
Then again i'm really graPPling with TIME now..
Later
being my next target.
so later...or mere moments
or any time not in the NOW.
But a now in the future or past makes later...
so... so..pluperfect?
Let's see it again.. i did flu and plu only
mere days ago iirc.
so..
http://en.wikipedia.org/wiki/Pluperfect
The pluperfect (from Latin plus quam perfectum more than perfect),
also called past perfect in English, is a grammatical combination of
past tense with the perfect, itself a combination of tense and aspect,
that exists in most Indo-European languages though there is not one in
Irish. It is used to refer to an event that had continuing relevance
to a past time.[dubious – discuss] Comrie[1]:p.64 classifies the
pluperfect as an absolute-relative tense because it absolutely (not by
context) establishes a deixis (the past event) and places the action
relative to the deixis (before it).
In the sentence "A man who for years had thought he had reached the
absolute limit of all possible suffering now found that suffering had
no limits, and that he could suffer still more, and more
intensely" (from Victor Frankl's Man's Search for Meaning), "had
thought" and "had reached" are examples of the pluperfect. They refer
to an event (a man thinking he has reached the limit of his capacity
to suffer), which takes place before another event (the man
discovering that his capacity to suffer has no limit), that are still
relevant at the time of the later event. Because that second,
subsequent event is itself a past event and the past tense is used to
refer to it ("a man...now found"), the pluperfect is needed to make it
clear that the first event (reaching the limit) has taken place even
earlier in the past.
<snip>
I read that search for meaning..
It was really....meaning------>FULL
http://en.wikipedia.org/wiki/Man%27s_Search_for_Meaning
If i have to go on obama care maybe i'll feel that whey?
Or will he make short shrift of me?
But if there are millions of me and those act like
Catholics on the pill/family planning issue then he
will reconsider it LATER?
And tack that bill on insurance which MEANs we ALL pay?
Obama needs to STAY the FREAK out of bizness that isn't his-ness.
When was or has he EVER been in business?
And since the democrats and repulicans are no more then
a business NOW with phoney baloney BS at the core,
then we can figure, that giving them power over
the national debt has put the final NAIL in the coffin of
amerika...
How does moooooooooooooooooooooooochele like it now?
The Heavy - How You Like Me Now?
http://www.youtube.com/watch?v=sVzvRsl4rEM
would you see right through me..
if i sing a real sad song would you give
it to ME...
How do LIKE me NOW..
Fork.... all LATERs
Does that make you love me BABY?
Does that make you want me BABY?
Heavy...
like
http://en.wikipedia.org/wiki/Man%27s_Search_for_Meaning
Man's Search for Meaning is a 1946 book by Viktor Frankl chronicling
his experiences as a concentration camp inmate and describing his
psychotherapeutic method of finding a reason to live. According to
Frankl, the book intends to answer the question "How was everyday life
in a concentration camp reflected in the mind of the average
prisoner?" Part One constitutes Frankl's analysis of his experiences
in the concentration camps, while Part Two introduces his ideas of
meaning and his theory of logotherapy. It is the second-most widely
read Holocaust book in the bookstore of the United States Holocaust
Memorial Museum
<snip>
ok is OK to say
later?
no freak it... i hate LATER
people who say... later...
I never want to ever talk to again..
so... LOL
later..
randall.. feeling very uncomfortable with the word LATER...why? it's
heavy?
> On Fri, 10 Feb 2012 15:19:06 -0800 (PST), randall <ranhu...@aol.com>
> >elimination half-life (511 ± 136 min); dose escalation (5-20 mg/kg)
>
> Doesn't that say 511 minutes, aka 8+ hours?
>
> But it may leave behind changes that last longer, if it works by
> binding to something that takes days to replenish.
>
> >But what is the half life of apremilast?
>
> http://www.google.com/search?q=apremilast+half-life&sourceid=ie7&rls=...
> Doesn't that say 511 minutes, aka 8+ hours?
>
> But it may leave behind changes that last longer, if it works by
> binding to something that takes days to replenish.
>
> >But what is the half life of apremilast?
>
>
> Looks also like about 8 hours.
>
> J.
J
> Looks also like about 8 hours.
>
> J.
You are correct.
8.51666666666666666666666666666666666666 hours to be.....
Anyway that goes to show.
It must not help my plain old brain calculator. LOL
Then again i'm really graPPling with TIME now..
Later
being my next target.
so later...or mere moments
or any time not in the NOW.
But a now in the future or past makes later...
so... so..pluperfect?
Let's see it again.. i did flu and plu only
mere days ago iirc.
so..
http://en.wikipedia.org/wiki/Pluperfect
The pluperfect (from Latin plus quam perfectum more than perfect),
also called past perfect in English, is a grammatical combination of
past tense with the perfect, itself a combination of tense and aspect,
that exists in most Indo-European languages though there is not one in
Irish. It is used to refer to an event that had continuing relevance
to a past time.[dubious – discuss] Comrie[1]:p.64 classifies the
pluperfect as an absolute-relative tense because it absolutely (not by
context) establishes a deixis (the past event) and places the action
relative to the deixis (before it).
In the sentence "A man who for years had thought he had reached the
absolute limit of all possible suffering now found that suffering had
no limits, and that he could suffer still more, and more
intensely" (from Victor Frankl's Man's Search for Meaning), "had
thought" and "had reached" are examples of the pluperfect. They refer
to an event (a man thinking he has reached the limit of his capacity
to suffer), which takes place before another event (the man
discovering that his capacity to suffer has no limit), that are still
relevant at the time of the later event. Because that second,
subsequent event is itself a past event and the past tense is used to
refer to it ("a man...now found"), the pluperfect is needed to make it
clear that the first event (reaching the limit) has taken place even
earlier in the past.
<snip>
I read that search for meaning..
It was really....meaning------>FULL
http://en.wikipedia.org/wiki/Man%27s_Search_for_Meaning
If i have to go on obama care maybe i'll feel that whey?
Or will he make short shrift of me?
But if there are millions of me and those act like
Catholics on the pill/family planning issue then he
will reconsider it LATER?
And tack that bill on insurance which MEANs we ALL pay?
Obama needs to STAY the FREAK out of bizness that isn't his-ness.
When was or has he EVER been in business?
And since the democrats and repulicans are no more then
a business NOW with phoney baloney BS at the core,
then we can figure, that giving them power over
the national debt has put the final NAIL in the coffin of
amerika...
How does moooooooooooooooooooooooochele like it now?
The Heavy - How You Like Me Now?
http://www.youtube.com/watch?v=sVzvRsl4rEM
would you see right through me..
if i sing a real sad song would you give
it to ME...
How do LIKE me NOW..
Fork.... all LATERs
Does that make you love me BABY?
Does that make you want me BABY?
Heavy...
like
http://en.wikipedia.org/wiki/Man%27s_Search_for_Meaning
Man's Search for Meaning is a 1946 book by Viktor Frankl chronicling
his experiences as a concentration camp inmate and describing his
psychotherapeutic method of finding a reason to live. According to
Frankl, the book intends to answer the question "How was everyday life
in a concentration camp reflected in the mind of the average
prisoner?" Part One constitutes Frankl's analysis of his experiences
in the concentration camps, while Part Two introduces his ideas of
meaning and his theory of logotherapy. It is the second-most widely
read Holocaust book in the bookstore of the United States Holocaust
Memorial Museum
<snip>
ok is OK to say
later?
no freak it... i hate LATER
people who say... later...
I never want to ever talk to again..
so... LOL
later..
randall.. feeling very uncomfortable with the word LATER...why? it's
heavy?
0 new messages