I've not ridden a road standard, but I've ridden 3 Rivendell road customs as well as a Ram, and I find that my customs -- note: all use so-called 26" wheels with lightish road tires -- are a noticeable bit quicker into the turns (while being equally stable in the straight line). The Ram is very nice, though, and -- as I put it to myself shortly after I got it -- feels a bit more confident coasting downhill at 30+ when you sit up, take one hand off the bar, and look 180 degrees behind you.
Second: the Ram, as well as my two remaining road customs, exhibits the very distinct quality which I have found with 4/5 of the Rivs I've owned, and only in a select few other bikes, that regardless of weight or wheels or tires, it makes me feel more energetic and makes it feel as if I can push a gear one tooth higher in all circumstances. IE, it feels lively and not dead. Again, regardless of weight, wheel weight, or tires.
As far as stiffness nor flexibility, I feel nothing different. But I may be entirely opaque to such things.