On 7/1/2021 5:54 PM, Brian Sandle wrote:
> What is known about the biochemistry of how calcium, phosphate, magnesium, fluoride are ordered to form apatite to repair tooth surface? Can it just happen randomly or might bacterial colonies of some types help as they develop layers on the tooth surface? Though I guess the first layer to develop after abrasive brushing would contain the acid forming Strep mutans?
>
There is an equilibrium of ions moving in and out at the enamel surface;
a persistent increase in concentration of calcium and phosphate ions
will tend to increase mineralization of enamel; a relative paucity of
ions, or a decrease in pH, will tend to move ions out of the enamel surface.
After cleaning, the first thing that collects on the surface is a
protein layer known as salivary pellicle. If left undisturbed, this
will be colonized by bacteria of a variety of species. Most bacteria
implicated in decay require oxygen; many implicated in periodontal
disease (not all) do not. For this reason, decay-causing bacteria
appear more quickly than perio d. causing bacteria.
Bacteria can utilize calcium ions too, but they process it within the
plaque and form dental calculus (tartar); it does not get incorporated
in the surface of the teeth.
Fluoride replaces hydroxyl groups in hydroxyapatite of the enamel to
form fluorapatite; it is more resistant to dissolution by bacterial
acids, which accounts for its anti-decay properties.
Steve