I replaced the USB B to A cable. Same thing. I had another Quadstick, but it had the same issue. I've tried multiple ports with no success. All other USB devices work fine. It worked fine for 2 days, but started this in the middle of the day. I was installing several programs at the time, but never opened them. I threw in the towel and hooked my old computer up, and its working fine now. The constant appearance of red lights 2 and 4 are gone.
On a side note, I don't think the pre-owned Quadstick I bought was "unused" as claimed. There's no RAM mount. I think he just took the old one off the mount and forgot to give it the other one. Other than the mouthpiece what else should I sterilize? As to why he sold it, I can't get softs to trigger on the side tube.