CALA Happy Hour

[Ke Yuan]

Dear members:

Thanks, everyone for joining our online brainstorm forum on COVID-19 today. Its a great turnout and heated discussion on this hot topic. With this great momentum, we have decided to start our weekly CALA online seminar on each Friday at 10:30 am-11:30am EST(7:30am PST, 10:30pm China time). Two speakers per week for 20 min each+ 10minQ&A. We promise to finish in one hour.

Topics are flexible, arranging from each lab's own research to share your scientific stories with the group or seek more complementary skillsets for collaborations( or anything you want to discuss, such as COVID-19, or even your daily life story)

Please sign up your name as speakers by following time slots:

https://docs.google.com/forms/d/e/1FAIpQLSda6ov0TATEozIHoCcqi1s9ewaVddy46J-0r8q3-kTEfaQeOw/viewform 

Thanks for your participation.

CALA 

 

[Ke Yuan]

2020 CALA Happy Friday Seminar

April 17th, 2020
Join Zoom Meeting:  https://zoom.us/join  
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Mitochondria and NLRP3 inflammasome in cigarette smoke associated with acute lung injury/ARDS

Dr. Qing Lu, Associate Professor, Brown University

Lab research focus and relevance to COVID-19

Dr. Jianwen Que, Associate Professor, Columbia University

See the enclosed flyer.

Stay safe and hope to see all of you soon.

CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar

April 24th, 2020

Join Zoom Meeting:  https://zoom.us/join   
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Check the enclosed flyer. 

Please sign up for future speakers here: https://docs.google.com/forms/d/e/1FAIpQLSda6ov0TATEozIHoCcqi1s9ewaVddy46J-0r8q3-kTEfaQeOw/viewform   

10:30-11:00 am EST  

Cigarette smoke-initiated autoimmunity in COPD: mechanisms and applications
Dr. Zhihua Chen
Professor, Zhejiang University

10:30-11:00 am EST    

Molecular Insights into COPD learned from GWAS
Dr. Xiaobo Zhou
Assistant Professor, Harvard University

Stay safe and hope to see all of you soon.

CALA

[Ke Yuan]

Mark your calendar for tomorrow morning "2020 CALA Happy Friday Seminar"

April 24th, 2020
Join Zoom Meeting:  https://zoom.us/join   
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Check the enclosed flyer. 

Please sign up for future speakers here: https://docs.google.com/forms/d/e/1FAIpQLSda6ov0TATEozIHoCcqi1s9ewaVddy46J-0r8q3-kTEfaQeOw/viewform   

10:30-11:00 am EST  

Cigarette smoke-initiated autoimmunity in COPD: mechanisms and applications
Dr. Zhihua Chen
Professor, Zhejiang University

10:30-11:00 am EST    

Molecular Insights into COPD learned from GWAS
Dr. Xiaobo Zhou
Assistant Professor, Harvard University

Stay safe and hope to see all of you tomorrow.

CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar 

May 1st, 2020 

Join Zoom Meeting:  https://zoom.us/join     

Meeting ID: 998-9099-1991 

Password: 397500 

Time: EST 10:00 am; PST: 7:00 am; Beijing time: 10:00 pm NOTE: TIME CHANGES TO 10AM

Check the enclosed flyer and Please sign up for future speakers here: https://docs.google.com/forms/d/e/1FAIpQLSda6ov0TATEozIHoCcqi1s9ewaVddy46J-0r8q3-kTEfaQeOw/viewform   

Identification of the lymphangioleiomyomatosis cell and its uterine origin 

Dr. Yan Xu 

Professor, Cincinnati Children’s Hospital   

10:00-10:45 am EST 

Every Scar Tells a Story: Current Understanding and Critical Issues of Lung Fibrosis 

Dr. Dianhua Jiang 

Professor, Cedars Sinai Medical Center  

10:45-11:30 am EST  

Stay safe and hope to see all of you this Friday.

CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar 

May 1st, 2020 

Join Zoom Meeting:  https://zoom.us/join     

Meeting ID: 998-9099-1991 

Password: 397500 

Time: EST 10:00 am; PST: 7:00 am; Beijing time: 10:00 pm NOTE: TIME CHANGES TO 10AM

Check the enclosed flyer and Please sign up for future speakers here: https://docs.google.com/forms/d/e/1FAIpQLSda6ov0TATEozIHoCcqi1s9ewaVddy46J-0r8q3-kTEfaQeOw/viewform   

Identification of the lymphangioleiomyomatosis cell and its uterine origin 

Dr. Yan Xu 

Professor, Cincinnati Children’s Hospital   

10:00-10:45 am EST 

Every Scar Tells a Story: Current Understanding and Critical Issues of Lung Fibrosis 

Dr. Dianhua Jiang 

Professor, Cedars Sinai Medical Center  

10:45-11:30 am EST  

Stay safe and hope to see all of you this Friday.

CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar

May 8th, 2020

Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

 

Host microenviroment associated antibiotic resistance and novel antimicrobial development   

Dr. Peter Di
Associate Professor, University of Pittsburg

Multi-drug resistant (MDR) bacterial infection has substantially increased in recent years and causes enormous concerns to public health. This talk will focus on the antibiotic resistance mechanisms and how host-pathogen interactions also contribute to the development of drug resistance. Novel antimicrobials with lower toxicity, polymyxin E will be presented. Dr. Peter Di has long standing interest in investigating the effects of environmental exposure including pathogenic microorganisms and toxic chemicals on the pathogenesis of pulmonary diseases. He has reviewed manuscripts for more than 60 different journals and grant applications for multiple funding agencies including more than 20 times of NIH study sections.  

Stay safe and hope to see all of you this Friday.
CALA

[Di, Y.P. Peter Ph.D.]

Hi, Ke:

 

Thanks for sending out the webinar announcement. I would like to make one minor clarification regarding the antimicrobial. Polymyxin E (colistin) is the clinically used antibiotic of last resort and we used it for comparison rather than as the focus of our study. We developed new antimicrobials that are superior to polymyxin E because of stronger potency, lower toxicity, and less resistance generation. I will share the progress of our antimicrobial development tomorrow. Best wishes and have a nice day.

 

Peter

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[Ke Yuan]

2020 CALA Happy Friday Seminar

May 15th, 2020

Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Respiratory viral infection: from acute morbidity to chronic sequelae.

Dr. Jie Sun
Associate Professor
Mayo Clinic

Acute respiratory viral infections including influenza and SARS-CoV2 infections impose great challenges to the public health. The disease pathogenesis associated with respiratory viral infections results from a combination of the deleterious effects of virus replication and the host innate and adaptive immune responses associated with control and, ultimately, clearance of virus.
Dr. Jie Sun is an associate professor in the Departments of Medicine and Immunology at the Mayo Clinic Alix School of Medicine. He has been reviewers for many Immunology and Pulmonary
Medicine journals, and served as standing or ad hoc members on a number of NIH or DoD grant review panels. The primary research goals of Dr. Jie Sun are to develop novel ideas and methods
for the induction of strong antiviral immunity, while minimizing collateral tissue damage and the development of chronic lung sequelae following respiratory viral infections.

Stay safe and hope to see all of you next Friday.
CALA  

[Ke Yuan]

2020 CALA Happy Friday Seminar

May 15th, 2020

Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Respiratory viral infection: from acute morbidity to chronic sequelae.

Dr. Jie Sun
Associate Professor
Mayo Clinic

Acute respiratory viral infections including influenza and SARS-CoV2 infections impose great challenges to the public health. The disease pathogenesis associated with respiratory viral infections results from a combination of the deleterious effects of virus replication and the host innate and adaptive immune responses associated with control and, ultimately, clearance of virus.
Dr. Jie Sun is an associate professor in the Departments of Medicine and Immunology at the Mayo Clinic Alix School of Medicine. He has been reviewers for many Immunology and Pulmonary
Medicine journals, and served as standing or ad hoc members on a number of NIH or DoD grant review panels. The primary research goals of Dr. Jie Sun are to develop novel ideas and methods
for the induction of strong antiviral immunity, while minimizing collateral tissue damage and the development of chronic lung sequelae following respiratory viral infections.

Stay safe and hope to see all of you this Friday.
CALA

[Ke Yuan]

 2020 CALA Happy Friday Seminar 

May 22nd, 2020 

Join Zoom Meeting: https://zoom.us/join 

Meeting ID: 998-9099-1991 

Password: 397500 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Interaction between alveolar epithelial stem cells and niches during lung repair 

Dr. Yuru Liu 

Associate Professor University of Illinois at Chicago 

Abstract: Type II alveolar epithelial cells are described as facultative stem cells based on their ability to proliferate and differentiate into type I cells. However, the signals sent by surrounding niches that activate the stem cell phenotype of type II cells during alveolar repair remain unclear. Using combinatorial approaches including mouse genetic lineage tracing analysis, tissue specific inducible gene targeting techniques, and 2D and 3D in vitro culture, we will demonstrate importance of Notch and YAP pathways regulating cell-cell communication and alveolar repair. Dr. Liu is an associate professor in Department of Pharmacology, University of Illinois at Chicago. Her research is focused on lung injury and repair, especially alveolar repair mediated by type II cells. Her group have used mouse lung injury models to define sub-population of type II cells for the progenitor cell function.   

Stay safe and hope to see all of you this Friday.
CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar 

May 22nd, 2020 

Join Zoom Meeting: https://zoom.us/join 

Meeting ID: 998-9099-1991 

Password: 397500 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Interaction between alveolar epithelial stem cells and niches during lung repair 

Dr. Yuru Liu 

Associate Professor University of Illinois at Chicago 

Abstract: Type II alveolar epithelial cells are described as facultative stem cells based on their ability to proliferate and differentiate into type I cells. However, the signals sent by surrounding niches that activate the stem cell phenotype of type II cells during alveolar repair remain unclear. Using combinatorial approaches including mouse genetic lineage tracing analysis, tissue specific inducible gene targeting techniques, and 2D and 3D in vitro culture, we will demonstrate importance of Notch and YAP pathways regulating cell-cell communication and alveolar repair. Dr. Liu is an associate professor in Department of Pharmacology, University of Illinois at Chicago. Her research is focused on lung injury and repair, especially alveolar repair mediated by type II cells. Her group have used mouse lung injury models to define sub-population of type II cells for the progenitor cell function.   

Stay safe and hope to see all of you tomorrow.
CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar     

May 29th, 2020 

Join Zoom Meeting: https://zoom.us/join 

Meeting ID: 998-9099-1991 

Password: 397500 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm 

Title: Generation of a three-dimensional lung organoid from human pluripotent stem cells and its applications

 Dr. Ya-Wen Chen Assistant Professor 

University of Southern California 

Abstract:

Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D) would allow deeper insight into human development, as well as the development of innovative strategies for disease modeling, drug discovery and regenerative medicine. In this talk, she will show how she systematically differentiates hPSCs to lung organoids and their applications to study human lung development, diseases, and regenerative medicine. Dr Chen’s research works were published in Nature Cell Biology and Protocol Exchange in 2017. Dr. Chen had post-doc training with Dr. Hans-Willem Snoeck in Columbia University, a leader in the stem cell biology field. She started her own independent lab last year in the University of Southern California.   

Stay safe and hope to see you all this Friday.
CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar     

May 29th, 2020 

Join Zoom Meeting: https://zoom.us/join 

Meeting ID: 998-9099-1991 

Password: 397500 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm 

Title: Generation of a three-dimensional lung organoid from human pluripotent stem cells and its applications

Dr. Ya-Wen Chen 

Assistant Professor 

University of Southern California 

Abstract:

Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D) would allow deeper insight into human development, as well as the development of innovative strategies for disease modeling, drug discovery and regenerative medicine. In this talk, she will show how she systematically differentiates hPSCs to lung organoids and their applications to study human lung development, diseases, and regenerative medicine. Dr Chen’s research works were published in Nature Cell Biology and Protocol Exchange in 2017. Dr. Chen had post-doc training with Dr. Hans-Willem Snoeck in Columbia University, a leader in the stem cell biology field. She started her own independent lab last year in the University of Southern California.   

Stay safe and hope to see you all tomorrow.
CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar 

June 5th, 2020 

Join Zoom Meeting: https://zoom.us/join 

Meeting ID: 998-9099-1991 

Password: 397500 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm 

Novel Mechanisms and Targets in Pulmonary Arterial Hypertension 

Dr. Zhiyu Dai 

Assistant Professor University of Arizona  

Abstract: Pulmonary artery hypertension (PAH) is characterized by progressive increase in pulmonary vascular resistance and obliterative pulmonary vascular remodeling that results in right heart hypertrophy and failure and premature death. Recently, we have reported the first mouse model of PAH [Egln1Tie2Cre mice] with progressive obliterative vascular remodeling including vascular occlusion and plexiform-like lesion and right heart failure, which recapitulates many features of clinical PAH. Using this unique model, we defined several novel molecular and cellular pathways(including smooth muscle cell hyperproliferation, augmentation of nitrative stress, dysregulation of lipid metabolism) that mediate the obliterative vascular remodeling of PAH, and identified several therapeutic targets (HIF-2a, FoxM1) that potentially treat the patients with PAH. Dr. Dai graduated from Sun Yat-sen University, China, and completed his postdoctoral training at University of Illinois at Chicago and Northwestern University. The lab is funded by NHLBI Pathway to Independence Award (Parent K99/R00) and ATS Foundation Research Program.  

Stay safe and hope to see you all tomorrow.
CALA  

[Ke Yuan]

2020 CALA Happy Friday Seminar 

June 12th, 2020 

Join Zoom Meeting: https://zoom.us/join 

Meeting ID: 998-9099-1991 

Password: 397500 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm 

Multi-omics Approach to Childhood Asthma 

Dr. Wei Chen 

Associate Professor University of Pittsburgh 

Abstract:

Athma is the most common chronic respiratory disease in children. Despite the success of genome-wide association studies, reported asthma-susceptibility loci can explained only ~3.5% of asthma heritability, supporting a strong contribution of environmental exposures to asthma causation. In this talk, Dr. Chen will describe recent advances of large-scale omics studies of asthma and relevant phenotypes including whole-genome transcriptomic and epigenetic studies. He will discuss how bioinformatic and statistical tools can help provide insight of asthma biology and prioritize candidate genes for downstream functional experiments. Dr. Chen received BS in Mathematics from Nanjing University and PhD in Biostatistics from the University of Michigan. Dr. Chen’s research focuses on developing statistical and computational methods for analyzing highthroughput genomics data. He has served as PI on multiple NIH grants and published over 100 peer reviewed papers in Nat Genet, Nat Comm, Nat Mach Intell, Lancet Respir Med, PNAS, AJRCCM, JACI, and ERJ.  

Stay safe and hope to see you all this Friday.
CALA  

[Ke Yuan]

2020 CALA Happy Friday Seminar 

 June 19th, 2020   

(Please note the change of Zoom link) 

Join Zoom Meeting: 

https://uahs.zoom.us/j/97032505774?pwd=ejZtTm1CVzRnc0YwbnJFNU1 rVUtUdz09

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm 

Lung injury and fibrosis from the metabolic viewpoint 

Dr. Gang Liu. M.D, Ph.D. 

Professor University of Alabama 

Abstract:

The role of cellular metabolism in pulmonary diseases has been increasingly recognized in recent years. In this presentation, Dr. Liu will guide you through how glycolysis, glutaminolysis and de novo amino acid synthesis regulate lung injury and fibrosis. Dr. Liu is a Professor and Principal Investigator at the Division of Pulmonary, Allergy and Critical Care Medicine, The University of Alabama at Birmingham (UAB). Dr. Liu went to Wuhan University for his Ph.D. degree, followed by postdoctoral training in Cell Biology at Medical College of Georgia and UAB. He joined UAB faculty in 2006. Dr. Liu's laboratory is currently supported by grants from NIH and DoD.   

Stay safe and see you all this Friday.

CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar 

 June 19th, 2020   

(Please note the Zoom Link change) 

Join Zoom Meeting: 

https://bit.ly/3e9uN8z 

 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm 

Lung injury and fibrosis from the metabolic viewpoint 

Dr. Gang Liu. M.D, Ph.D. 

Professor University of Alabama 

Abstract:

The role of cellular metabolism in pulmonary diseases has been increasingly recognized in recent years. In this presentation, Dr. Liu will guide you through how glycolysis, glutaminolysis and de novo amino acid synthesis regulate lung injury and fibrosis. Dr. Liu is a Professor and Principal Investigator at the Division of Pulmonary, Allergy and Critical Care Medicine, The University of Alabama at Birmingham (UAB). Dr. Liu went to Wuhan University for his Ph.D. degree, followed by postdoctoral training in Cell Biology at Medical College of Georgia and UAB. He joined UAB faculty in 2006. Dr. Liu's laboratory is currently supported by grants from NIH and DoD.   

Stay safe and see you soon.

CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar 

 June 26th, 2020   

(Please note the Zoom Link change) 

Join Zoom Meeting: 

https://bit.ly/3e9uN8z 

 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm 

The driving force of alveolar development, regeneration, and fibrosis
Dr. Nan Tang. M.D, Ph.D.
Associate Investigator,
National Institute of Biological Sciences

The coordinated influences of both mechanical forces and growth factors during tissue development and regeneration is extremely important. With an integrated combination of mouse genetics, live imaging, lineage tracing, and quantitative cell biology, we demonstrate that alveolar development and regeneration are controlled by both mechanical forces and a local growth factor.
We have also established a direct mechanistic link between impaired alveolar regeneration, mechanical tension, and progressive lung fibrosis.
Dr. Tang obtained her Ph.D from UCSD, followed by a post-doctoral training at UCSF. She joined NIBS faculty in 2012 and has numerous high-impact publications ever since in Lancet, Cell , Dev Cell and PNAS et al.

Stay safe and see you this Friday.

CALA

[Ke Yuan]

Dear CALA members,

We will not have a webinar this Friday due to the University Holiday (Dr. Carol Jiang's talk will be July 17th). We will resume on July 10th.

Happy July 4th everyone! 

Stay Safe.

CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar 

July 7th

Join Zoom Meeting: 

https://bit.ly/3e9uN8z 

 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm 

Stem Cell Approach to Small Cell Lung Cancer and COVID-19

Huanhuan Joyce Chen PharmD. PhD. 

Assistant Professor

University of Chicago

ABSTRACT: Current cancer research is hindered by the limitations of existing experimental systems, which fall short in demonstrating concordance with human studies. In this way, we aim to develop models for studying mechanisms that initiate and progress carcinogenesis, focusing initially on Small Cell Lung Cancer (SCLC), the most aggressive type of lung cancer. My currently developed cell culture models based on directed differentiation of human pluripotent stem cells (hPSC) reveal why certain constellations of genetic changes drive carcinogenesis in specialized human cell lineages. These tractable experimental systems enable studying cancer in great depth, using genetically defined human cells that can be characterized at the single cell level. I will also describe our recent work in studying COVID-19 using the cells derived from hPSCs.

 

Dr. Chen graduated with PhD at Cornell University, and did post-doctoral training with Dr. Harold Varmus at Weill Cornell Medicine. She joins University of Chicago as assistant professor in 2020 as a K99/R00 awardee and has many papers published in Nature Biotech, Nature Med, Cell Stem Cell, JEM and JCI etc.

Stay safe and see you this Friday.

CALA

[Ke Yuan]

2020 CALA Happy Friday Seminar 

July 10th

Join Zoom Meeting: 

https://bit.ly/3e9uN8z 

 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm 

Stem Cell Approach to Small Cell Lung Cancer and COVID-19

Huanhuan Joyce Chen PharmD. PhD. 

Assistant Professor

University of Chicago

ABSTRACT: Current cancer research is hindered by the limitations of existing experimental systems, which fall short in demonstrating concordance with human studies. In this way, we aim to develop models for studying mechanisms that initiate and progress carcinogenesis, focusing initially on Small Cell Lung Cancer (SCLC), the most aggressive type of lung cancer. My currently developed cell culture models based on directed differentiation of human pluripotent stem cells (hPSC) reveal why certain constellations of genetic changes drive carcinogenesis in specialized human cell lineages. These tractable experimental systems enable studying cancer in great depth, using genetically defined human cells that can be characterized at the single cell level. I will also describe our recent work in studying COVID-19 using the cells derived from hPSCs.

 

Dr. Chen graduated with PhD at Cornell University, and did post-doctoral training with Dr. Harold Varmus at Weill Cornell Medicine. She joins University of Chicago as assistant professor in 2020 as a K99/R00 awardee and has many papers published in Nature Biotech, Nature Med, Cell Stem Cell, JEM and JCI etc.

Stay safe and see you soon.

CALA

[Beiyun Zhou]

I can not log in, It says the meeting ID is not valid.

 

From: lunginte...@googlegroups.com <lunginte...@googlegroups.com> On Behalf Of Ke Yuan
Sent: Friday, July 10, 2020 6:22 AM
To: lunginte...@googlegroups.com
Subject: Re: CALA Happy Hour

 

2020 CALA Happy Friday Seminar 

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You received this message because you are subscribed to the Google Groups "LungInterestGroup" group.
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To view this discussion on the web visit https://groups.google.com/d/msgid/lunginterestgroup/CAO%2BFyMzTeKXB7BBPg%3D%3Dbzuon--3an4EUoYfoEJ0fR3KCrcg5ew%40mail.gmail.com.

[Xiaobo Zhou]

You ca use this link

https://arizona.zoom.us/j/97032505774 (Password: 654321)

To view this discussion on the web visit https://groups.google.com/d/msgid/lunginterestgroup/BY5PR07MB6514536F40D17D3D05BEB0EAAF650%40BY5PR07MB6514.namprd07.prod.outlook.com.

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http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.

[Hongpeng Jia]

Neither do I. the same error.

 

Hongpeng Jia

Assistant Professor

Division of Pediatric Surgery

Department of Surgery

Johns Hopkins University School of Medicine

Office: 735A Ross building

Tel: 410-955-3429

Email: hj...@jhmi.edu

 

From: <lunginte...@googlegroups.com> on behalf of Beiyun Zhou <bz...@usc.edu>
Reply-To: "lunginte...@googlegroups.com" <lunginte...@googlegroups.com>
Date: Friday, July 10, 2020 at 10:32 AM
To: "lunginte...@googlegroups.com" <lunginte...@googlegroups.com>
Subject: RE: CALA Happy Hour

 

      External Email - Use Caution      

 

 

To view this discussion on the web visit https://groups.google.com/d/msgid/lunginterestgroup/BY5PR07MB6514536F40D17D3D05BEB0EAAF650%40BY5PR07MB6514.namprd07.prod.outlook.com.

[Beiyun Zhou]

Got in, thanks!

To view this discussion on the web visit https://groups.google.com/d/msgid/lunginterestgroup/26134E30-6FC6-48AC-A77C-61E59825C2F3%40channing.harvard.edu.

[Ke Yuan]

Please use this link

https://arizona.zoom.us/j/97032505774 (Password: 654321)

To view this discussion on the web visit https://groups.google.com/d/msgid/lunginterestgroup/BY5PR07MB6514E4511CB8AA407E09D2E9AF650%40BY5PR07MB6514.namprd07.prod.outlook.com.

[Ke Yuan]

CALL FOR TALENT

各位朋友，CALA打算在7月24日美东时间10:30am举办CALA Summer Party，现在请各位成员积极报名CALA Talent Show，展示自己学术外的风采，一站成名的好机会！欢迎唱歌，跳舞和其他各类才艺表演，每个节目2-3分钟，也可多人在线表演！  报名截止7月23日

请和Ke积极报名: yuank...@gmail.com

多谢大家对CALA的支持

[Ke Yuan]

1. CALL FOR INPUT

Dear Cala Members,

We are going to have a CALA annual party on July 24th. We would like to recognize the members' achievements in the past year. Please take a few minutes to fill the survey by July 22. Thanks.

https://forms.gle/7rCvXV4XyiCfPNNP6 Or you can reply to my email for these questions:

1. Did you get a promotion or move to a new institute in the past year? Please let us know what position and what institute.

2. Were you awarded a new grant or award? Please let us know the grant title, PI, funding agent and period.

3. Do you have any recent publications to share with our community? Please let us know the PMID or a link to track.

4. Do you have any news to share with our community? We would like to celebrate with you.

2. CALL FOR TALENT

各位朋友，CALA打算在7月24日美东时间10:30am举办CALA Summer Party，现在请各位成员积极报名CALA Talent Show，展示自己学术外的风采，一站成名的好机会！欢迎唱歌，跳舞和其他各类才艺表演，每个节目2-3分钟，也可多人在线表演！  报名截止7月23日

请和Ke积极报名: yuank...@gmail.com

多谢大家对CALA的支持

[Ke Yuan]

2020 CALA Happy Friday Seminar 

July 17h 2020

Zoom Link:

https://arizona.zoom.us/j/97032505774 (Password: 654321)  

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm  

 

Title: Zinc Metabolic Defect of Aging Alveolar Progenitors in IPF
Dr. Carol Jiurong Liang

Assistant professor
Cedars-Sinai Medical Center

Abstract: Idiopathic pulmonary fibrosis (IPF) is a fatal form of interstitial lung disease and aging has been identified as a risk factor to the disease. We recently reported that there was a significant loss of alveolar progenitors (AEC2s) in the lungs of patients with IPF. In our current study, we performed single cell RNA-seq of AEC2s from patients with IPF and healthy donors as well as AEC2s from old and young mouse lungs with bleomycin injury. We identified a defect of zinc metabolism in AEC2s from IPF lungs and bleomycin-injured old mouse lungs. We further demonstrated that a specific zinc transporter ZIP8 is associated with AEC2 renewal through sirtuin signaling in aging and in IPF. Targeted deletion of Zip8 in murine AEC2 compartment leads to reduced AEC2 renewal capacity, and impaired AEC2 recovery after bleomycin injury. In summary, we have identified novel metabolic defects of AEC2s during aging and in IPF which contribute to the pathogenesis of lung fibrosis. Therapeutic strategies to restore critical components of these metabolic programs could improve AEC2 progenitor activity and mitigate ongoing fibrogenesis. 

Stay safe and see you tomorrow,

CALA

[Ke Yuan]

1. CALL FOR INPUT

Dear Cala Members,

We are going to have a CALA annual party on July 24th. We would like to recognize the members' achievements in the past year. Please take a few minutes to fill the survey by July 22. Thanks.

https://forms.gle/7rCvXV4XyiCfPNNP6 Or you can reply to my email for these questions:

1. Did you get a promotion or move to a new institute in the past year? Please let us know what position and what institute.

2. Were you awarded a new grant or award? Please let us know the grant title, PI, funding agent and period.

3. Do you have any recent publications to share with our community? Please let us know the PMID or a link to track.
4. Do you have any news to share with our community? We would like to celebrate with you.

2. CALL FOR TALENT

各位朋友，CALA打算在7月24日美东时间10:30am举办CALA Summer Party，现在请各位成员积极报名CALA Talent Show，展示自己学术外的风采，一站成名的好机会！欢迎唱歌，跳舞和其他各类才艺表演，每个节目2-3分钟，也可多人在线表演！  报名截止7月23日

请和Ke积极报名: yuank...@gmail.com

多谢大家对CALA的支持

[Ke Yuan]

2020 CALA Annual Meeting
July 24th, 2020

Join Zoom Meeting: https://arizona.zoom.us/j/97032505774 (Password: 654321)

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Agenda
10:35-10:40am: Brief Intro of CALA History by Dr. Dianhua Jiang
10:40-11:15am: CALA 2020 Keynote Talk—moderated by Dianhua Jiang

从不明原因的病毒性肺炎到COVID-19
Dr. Bin Cao
Vice president and Director
Respiratory and Critical Care Medicine at the China-Japan Friendship Hospital in Beijing

11:15-11:30am: CALA Got Talent Show Part 1, hosted by Dr. Ke Yuan
11:30-11:40am: CALA 2019-2020 Activities Summary by Dr. Xiaobo Zhou
11:40-11:45am: CALA 2019-2020 Financial Report by Dr. Yin Chen
11:45-11:50am: CALA Members update (6/2019-7/2020) by Dr. Zhiyu Dai
11:50-12pm: CALA Got Talent Show Part 2, hosted by Dr. Ke Yuan
12pm: Closing remarks by Dr. Xiaobo Zhou

Stay safe and see you this Friday.

CALA

[Juan Hou]

Wow, such a packed agenda and seems going to be fun and informative!

Thanks to the CALA committee for your effort to put all these together!

Looking forwards to our annual meeting,

Juan 

To view this discussion on the web visit https://groups.google.com/d/msgid/lunginterestgroup/CAO%2BFyMypf-MmHNY1yty76b-xrohbRxw0_-ORgw%3DtVUEdbSFw-w%40mail.gmail.com.

--

---

JUAN HOU   PhD
SENIOR SCIENTIST
RESEARCH & DEVELOPMENT

VANCOUVER,  BC  CANADA
T. 604 675 7701 • 1 800 667 0322     F. 604 877 0704 • 1 800 567 2899    E.  JUAN...@STEMCELL.COM    W.  WWW.STEMCELL.COM

CONNECT WITH STEMCELL:               

Disclaimer: The content of this e-mail is intended solely for the use of the Individual or entity to whom it is addressed. If you have received this communication in error, be aware that forwarding it, copying it, or in any way disclosing its content to any other person, is strictly prohibited. If you have received this communication in error, please notify the author by replying to this e-mail immediately.

[Ke Yuan]

2020 CALA Annual Meeting
July 24th, 2020

Join Zoom Meeting: https://arizona.zoom.us/j/97032505774 (Password: 654321)
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Agenda
10:35-10:40am: Brief Intro of CALA History by Dr. Dianhua Jiang
10:40-11:15am: CALA 2020 Keynote Talk—moderated by Dianhua Jiang

从不明原因的病毒性肺炎到COVID-19
Dr. Bin Cao
Vice president and Director
Respiratory and Critical Care Medicine at the China-Japan Friendship Hospital in Beijing

11:15-11:30am: CALA Got Talent Show Part 1, hosted by Dr. Ke Yuan
11:30-11:40am: CALA 2019-2020 Activities Summary by Dr. Xiaobo Zhou
11:40-11:45am: CALA 2019-2020 Financial Report by Dr. Yin Chen
11:45-11:50am: CALA Members update (6/2019-7/2020) by Dr. Zhiyu Dai
11:50-12pm: CALA Got Talent Show Part 2, hosted by Dr. Ke Yuan
12pm: Closing remarks by Dr. Xiaobo Zhou

Stay safe and see you soon.

CALA

To view this discussion on the web visit https://groups.google.com/d/msgid/lunginterestgroup/CAPKoOwXN88T_7_yKbUM162r46Of3vi5R4es6icEibn%3DVJWNLmw%40mail.gmail.com.

[Ke Yuan]

2020 CALA Happy Friday Seminar

July 31st , 2020

Zoom Link:

https://arizona.zoom.us/j/97032505774 (Password: 654321)  

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Title: Supraglottic Lung Microbiome Taxa and Pulmonary Abnormalities in an HIV Longitudinal Cohort

Jin Zhou PhD
Associate Professor
Epidemiology & Biostatistics Department
University of Arizona

Abstract: Human immunodeficiency virus-1 infection (HIV) increases risk of non-infectious pulmonary complications. We hypothesize that an altered lung microbiome is associated with lung inflammation and evidence of lung disease. We examined the association between lung microbiome, lung function and pulmonary inflammation longitudinally in an HIV infected population before and after antiretroviral treatment (ART). We further characterized the dynamics of two distinct lung microbiome pneumotypes over time after starting ART. Thirty patients with a diagnosis of HIV and relatively advanced disease were followed in up to three visits for a maximum of three years after starting ART. At each visit, we performed pulmonary function test (PFT) and bronchoscopy with bronchoalveolar lavage (BAL) collection. The genus-level taxa were divided into two pneumotypes: supraglottic predominant (pneumotypeSPT) or background predominant (pneumotypeBPT) taxa. Weighted Spearman was used to identify genus-level taxa significantly correlated with lung function and inflammatory markers. Among eight genera that had significant positive correlations with inflammatory chemokine/cytokine levels in BAL (i.e., interleukin-8, inducible protein-10, monokine induced by IFN-γ, and interleukin-6), five were pneumotypeSPT. Subjects with higher SPT/BPT ratios had higher levels of inflammation. The presence of SPT taxa was associated with worse pulmonary function.  Previously defined BPT and SPT microbial taxa had different effect on inflammation markers and lung function in an HIV positive population. The complex lung function-microbiome-inflammatory network suggests that lung microbiome may play a critical role in modulating lung function of HIV infected individuals.

Stay safe and see you this Friday.

CALA

[Ke Yuan]

Dear CALA member, 

Due to the conflict of ATS 2020, we are NOT going to host a seminar this Friday, Aug 7th. 

Please mark your calendar for the next webinar, which will be Aug 28th, 

Title: Targeting CBLB as an Effective Approach to Boost TFH Responses Against Influenza A Virus Infection

Presenter:
Jian Zhang, M.D.
Professor of Pathology
Endowed Chair in Immunology Research
University of Iowa Health Care Distinguished Scholar
Department of Pathology
The University of Iowa 

Look forward to meeting everyone on Aug 28th.

CALA

[Ke Yuan]

2020 CALA Friday Seminar
August 28th, 2020

Zoom Link:

https://arizona.zoom.us/j/97032505774 (Password: 654321)  

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm  

Speaker: 

Jian Zhang, M.D.
Professor of Pathology
Endowed Chair in Immunology Research
University of Iowa Health Care Distinguished Scholar

Title: Targeting CBLB as an Effective Approach to Boost TFH Responses Against Influenza A Virus Infection

Abstract: T follicular helper (TFH) cells are CD4+ T cells specialized in providing help for germinal center (GC) formation, and the development of most high-affinity antibodies which are crucial for protective immune responses against pathogens. However, the negative regulation of TFH cell development is largely unknown. Here, we report that loss or inactivation of Cbl-b in mice facilitates TFH cell development, and protects mice from a lethal infection with influenza A virus (IAV), which correlates with heightened TFH responses and an expansion of GC B cells and plasma cells. T cell-intrinsic Cbl-b is critical for this process by binding to Bcl-6 and targeting Bcl-6 for polyubiquitination and degradation. Silencing the Cblb gene in vivo protects mice from lethal IAV infection, and enhances TFH-mediated Ab responses to influenza vaccination. Therefore, targeting Cbl-b may function as an effective adjuvant to boost immune responses to influenza vaccination, or represent potential therapeutic approaches for lethal RNA viral infections.

Look forward to meeting everyone this Friday.

CALA

[Ke Yuan]

2020 CALA Friday Seminar
August 28th, 2020

Zoom Link:

https://arizona.zoom.us/j/97032505774 (Password: 654321)  

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm  

Speaker: 

Jian Zhang, M.D.
Professor of Pathology
Endowed Chair in Immunology Research
University of Iowa Health Care Distinguished Scholar

Title: Targeting CBLB as an Effective Approach to Boost TFH Responses Against Influenza A Virus Infection

Abstract: T follicular helper (TFH) cells are CD4+ T cells specialized in providing help for germinal center (GC) formation, and the development of most high-affinity antibodies which are crucial for protective immune responses against pathogens. However, the negative regulation of TFH cell development is largely unknown. Here, we report that loss or inactivation of Cbl-b in mice facilitates TFH cell development, and protects mice from a lethal infection with influenza A virus (IAV), which correlates with heightened TFH responses and an expansion of GC B cells and plasma cells. T cell-intrinsic Cbl-b is critical for this process by binding to Bcl-6 and targeting Bcl-6 for polyubiquitination and degradation. Silencing the Cblb gene in vivo protects mice from lethal IAV infection, and enhances TFH-mediated Ab responses to influenza vaccination. Therefore, targeting Cbl-b may function as an effective adjuvant to boost immune responses to influenza vaccination, or represent potential therapeutic approaches for lethal RNA viral infections.

Look forward to meeting everyone.

CALA

[Ke Yuan]

2020 CALA Special Friday Seminar
Sep 18th, 2020 

Zoom Link:

https://arizona.zoom.us/j/97032505774 (Password: 654321)  

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm    

Pave The Way To Independence
-All about career development grants and job applications

When & How to apply for a job?

How to write an attractive Career plan for K99/R00?

Are there other career development opportunities?

How to apply for the 1st R01?

Panelists:
Dr. Yin Chen
Associate Professor,
University of Arizona

Dr. Yuanpu Peter Di

Associate Professor
University of Pittsburgh 

Dr. Dianhua Jiang
Professor
Cedars Sinai  

 

Dr. Huanhuan Joyce Chen (K99/R00 Awardee)

Assistant Professor
University of Chicago

Dr. Zhiyu Dai (K99/R00 Awardee)

Assistant Professor
University of Arizona

Dr. Ke Yuan (Parker B Francis Awardee)

Assistant Professor
Boston Children's Hospital

Moderator: Dr. Yan Hu (F32 awardee)
Postdoc Fellow, University of Colorado Anschutz

Look forward to meeting everyone soon.

CALA

[Ke Yuan]

Today at 10:30am, see u soon.

CALA

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[Ke Yuan]

2020 CALA  Friday Seminar

Oct 23rd, 2020 

Zoom Link:

https://arizona.zoom.us/j/97032505774 (Password: 654321)  

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm      

mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation

Dr. Longshuang Huang
Research Assistant Professor
The University of Illinois at Chicago 

Dr. Huang obtained his Ph.D. at Chungnam National University, Korea. He had postdoctoral training at Louisiana State University and the University of Illinois at Chicago. Currently, he is a Research Assistant Professor at the Department of Pharmacology, College of Medicine, the University of Illinois at Chicago. His research interests include idiopathic pulmonary fibrosis, acute lung injury and pulmonary hypertension. He has publications in many high-profile journals including Immunity, AJRCCM, Thorax et al.

Look forward to meeting everyone next week.

CALA

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but does not contain patient information, please contact the sender and properly
dispose of the e-mail.

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[Ke Yuan]

Dear all, the webinar is on going now. CALA

[Ke Yuan]

2020 CALA  Friday Seminar

Nov 20th, 2020 

Zoom Link:

https://arizona.zoom.us/j/97032505774 (Password: 654321)  

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm    

Role of Sphingolipid Pathways in the Pathobiology of Pulmonary Arterial Hypertension

Jiwang Chen, PhD
Director, Cardiovascular Research Core
Research Associate Professor
Division of Pulmonary, Critical Care, Sleep & Allergy
Department of Medicine

University of Illinois at Chicago

Abstract: Sphingosine kinase 1 (SphK1) regulates the synthesis of the bioactive sphingolipid sphingosine 1-phosphate (S1P), an important lipid mediator that promotes endothelial cell proliferation, migration and angiogenesis. Serum S1P activates YAP1 signaling pathways and YAP1 activation promotes cell proliferation. We first reported that SphK1 mRNA and protein levels were significantly up-regulated in pulmonary artery smooth muscle cells (PASMCs) isolated from patients with pulmonary arterial hypertension (PAH). Later we further investigated whether smooth muscle cell conditional SphK1 deficient (SM22αCre+SphK1f/f) mice are protected from experimental models of pulmonary hypertension (PH) and whether YAP1 plays a role in SphK1-mediated PH development. We demonstrated that SM22αCre+SphK1f/f mice are protected against hypoxia or hypoxia plus sugen mediated pulmonary hypertension. S1P or hypoxia activate YAP1 signaling by enhancing its translocation to the nucleus. YAP1 translocation is dependent on SphK1 enzymatic activity. We also showed that a YAP1 specific inhibitor, verteporfin, blocks S1P mediated proliferation in human PASMCs and attenuates hypoxia-mediated PH and pulmonary vascular remodeling in mice or hypoxia Sugen mediated severe PH in rats. We conclude that smooth muscle cell specific SphK1 plays an essential role in PH via YAP1 signaling. YAP1 inhibition may have a therapeutic effect for PH.

Look forward to meeting everyone next Friday.

CALA

[Ke Yuan]

Dear CALA members,

 

According to Article VI in the “By-Laws of Chinese-American Lung Association (CALA)”, it is time to elect a new Treasurer of CALA. I would like to call for nomination or self-nomination of candidates for the next Treasurer of CALA.

 

Eligibility: The nominee must be a CALA Full Member.

Responsibility if elected: 1. Prepare agenda and record meeting minutes at each meeting. 2. Present a financial report at the Annual Board of Governors meeting and Annual Membership Meeting, 3. Attend to general affairs of the Association including By-Laws amendments, website maintenance, as well as other assignments from the President. 4. To serve as the next President-Elect, and then the next President. More details regarding the responsibilities of the Treasurer can be found in the attached “By-Laws of CALA” (http://mycala.org/by-laws.html).

 

Nomination procedure:  Nominations including self-nominations are invited. Please submit the nominee’s name, institute, and email address by Nov 31 2020 to: Zhiyu Dai PhD at zhiy...@email.arizona.edu.

 

Best,

 

Zhiyu

[Ke Yuan]

Ke Yuan <yuank...@gmail.com>	Sun, Nov 8, 5:30 PM (4 days ago)
to lunginterestgroup

2020 CALA  Friday Seminar

Nov 20th, 2020 

Zoom Link:

https://arizona.zoom.us/j/97032505774 (Password: 654321)  

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 11:30 pm (not 10:30pm)   

Role of Sphingolipid Pathways in the Pathobiology of Pulmonary Arterial Hypertension

Jiwang Chen, PhD
Director, Cardiovascular Research Core
Research Associate Professor
Division of Pulmonary, Critical Care, Sleep & Allergy
Department of Medicine
University of Illinois at Chicago

Abstract: Sphingosine kinase 1 (SphK1) regulates the synthesis of the bioactive sphingolipid sphingosine 1-phosphate (S1P), an important lipid mediator that promotes endothelial cell proliferation, migration and angiogenesis. Serum S1P activates YAP1 signaling pathways and YAP1 activation promotes cell proliferation. We first reported that SphK1 mRNA and protein levels were significantly up-regulated in pulmonary artery smooth muscle cells (PASMCs) isolated from patients with pulmonary arterial hypertension (PAH). Later we further investigated whether smooth muscle cell conditional SphK1 deficient (SM22αCre+SphK1f/f) mice are protected from experimental models of pulmonary hypertension (PH) and whether YAP1 plays a role in SphK1-mediated PH development. We demonstrated that SM22αCre+SphK1f/f mice are protected against hypoxia or hypoxia plus sugen mediated pulmonary hypertension. S1P or hypoxia activate YAP1 signaling by enhancing its translocation to the nucleus. YAP1 translocation is dependent on SphK1 enzymatic activity. We also showed that a YAP1 specific inhibitor, verteporfin, blocks S1P mediated proliferation in human PASMCs and attenuates hypoxia-mediated PH and pulmonary vascular remodeling in mice or hypoxia Sugen mediated severe PH in rats. We conclude that smooth muscle cell specific SphK1 plays an essential role in PH via YAP1 signaling. YAP1 inhibition may have a therapeutic effect for PH.

Look forward to meeting everyone next Friday.

CALA

[Ke Yuan]

Today !!! See u soon. 2020 CALA  Friday Seminar

Nov 20th, 2020 

Zoom Link:

https://arizona.zoom.us/j/97032505774 (Password: 654321)  

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 11:30 pm (not 10:30pm)   

Role of Sphingolipid Pathways in the Pathobiology of Pulmonary Arterial Hypertension

Jiwang Chen, PhD
Director, Cardiovascular Research Core
Research Associate Professor
Division of Pulmonary, Critical Care, Sleep & Allergy
Department of Medicine
University of Illinois at Chicago

[Ke Yuan]

Please Vote new Treasurer, a message from Zhiyu Dai

We received nominations for the following faculty as candidates for our new Treasurer.

 

Ke Yuan, PhD, Assistant Professor, Boston Children's Hospital, https://www.childrenshospital.org/research/researchers/y/ke-yuan

 

Wei Chen, PhD, Associate Professor, University of Pittsburgh, http://www.pitt.edu/~wec47/

 

Jianwen Que, MD, PhD, Professor, Columbia University, https://columbiauni.wixsite.com/quelab

 

please vote by 12/19/20 12am EST through this link,

https://docs.google.com/forms/d/1wyP63uUeTipyo8x42hQ_taU3P9E-YQis4oCfT2Wsb8Q/edit, or email me zhiy...@arizona.edu.

[Ke Yuan]

 2020 CALA Happy Friday Seminar 

Dec 18th, 2020 

Join Zoom Meeting: https://arizona.zoom.us/j/82407021221 (Password: 654321) 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 11:30 pm 

Type 17 Mucosal Immunity 

Jay K. Kolls MD 

Professor of Medicine and Pediatrics. 

John W Deming Endowed Chair in Internal Medicine. 

Director, Center for Translational Research in Infection and Inflammation. 

Tulane University School of Medicine. 

Abstract: Dr. Kolls is a pioneer in Type 17 immunity. He has been continuously funded by the NIH for 25 years for work on lung/mucosal immunology. He identified IL-17 and IL-22, cytokines produced by T cells and innate lymphoid cells that are critical to pulmonary host defense to extracellular bacteria and viruses such as influenza and RSV. He showed that the receptors for these cytokines are critical for mucosal immune responses in the lung and gut. He also demonstrated that antigen specific memory Th17 cells can mediate clade specific immunity against Enterobacteriaceae including multi-drug resistant Klebsiella pneumonia. Moreover, he showed that IL-17RA signaling contributes to lung injury induced by H1N1 influenza. His recent focus is on the understanding of mucosal immunity to pathogens including SARSCOV-2  

[Ke Yuan]

2020 CALA Happy Friday Seminar 

Dec 18th, 2020 

Join Zoom Meeting: https://arizona.zoom.us/j/82407021221 (Password: 654321) 

Time: EST 10:30 am; PST: 7:30 am; Beijing time: 11:30 pm 

Type 17 Mucosal Immunity 

Jay K. Kolls MD 

Professor of Medicine and Pediatrics. 

John W Deming Endowed Chair in Internal Medicine. 

Director, Center for Translational Research in Infection and Inflammation. 

Tulane University School of Medicine. 

See u tomorrow morning.

CALA

[Ke Yuan]

Christmas Party on going

12/19/2020

8-9pm EST, 5-6pm PST

Zoom ID: 95643292910

[Ke Yuan]

Dear CALA members,

Happy new year.

Welcome to the 2021 CALA workshop series

Transform Scientific Discoveries from a Lab to a Startup 101
January 22nd , 2021 

Time: EST 4-5pm; PST: 1-2pm
(zoom ID: 988 2664 9654; Passcode: CALA2021)

Moderated by Xiaobo Zhou, Ph.D.  

Dr. George Dai, M.B.A., Ph.D. Co-Chief Investment Officer, Weatherbie Capital, LLC
George Dai is Senior Managing Director and Co-Chief Investment Officer of Weatherbie Capital, LLC. George is the lead Portfolio Manager of Alger Weatherbie Specialized Growth Strategy and Weatherbie Long/Short Strategy. Under his leadership, The Alger Weatherbie Specialized Growth Strategy has achieved top performances in recent years, including being ranked #1 in the Mid-Cap Growth Category during the first quarter of 2019. George has been featured and quoted in a number of publications in leading journals such as New York Times, Investor’s Business Daily and Barron’s. He was also interviewed on Reuters Television. George received his MBA from the Wharton School, University of Pennsylvania (Director’s List), and his Ph.D. in chemistry from Johns Hopkins University. Previously, he earned a B.S. from the University of Science and Technology of China and was a pharmaceutical research scientist at Procter & Gamble. George is a prized Bridge player, and he holds four U.S. patents.

Peng Lin, Ph.D. J.D, Patent Attorney, Associate, Fish & Richardson
Peng Lin is a patent attorney at Fish & Richardson. He focused on his practice on worldwide patent procurement, patent portfolio management, and strategic planning for life sciences companies. He is currently helping several big Chinese pharmaceutical and biotech companies to develop their IP strategies. Peng received his J.D. cum laude from Harvard Law School, and his Ph.D. in Human and Statistical Genetics from Washington University in St. Louis. He was also named as a Kauffman Fellow for Bio-entrepreneurship at Washington University. Prior to graduate school, Peng earned his B.S. in Biological Science with high honors from Tsinghua University. In addition, Peng has also been actively involved in the management team of the Chinese Antibody Society since 2016. He is currently the vice president of Chinese Antibody Society.

Topics to cover: how to translate scientific findings to biomedical products; Keys to protect scientific discoveries by IP; Tips to attract private and public investment et al.

Look forward to meeting everyone soon.

CALA

[Ke Yuan]

Welcome to the 2021 CALA workshop series

Transform Scientific Discoveries from a Lab to a Startup 101

January 22nd, 2021 

Time: EST 4-5pm; PST: 1-2pm
(zoom ID: 988 2664 9654; Passcode: CALA2021)

Moderated by Xiaobo Zhou, Ph.D.  

Dr. George Dai, M.B.A., Ph.D. Co-Chief Investment Officer, Weatherbie Capital, LLC
George Dai is Senior Managing Director and Co-Chief Investment Officer of Weatherbie Capital, LLC. George is the lead Portfolio Manager of Alger Weatherbie Specialized Growth Strategy and Weatherbie Long/Short Strategy. Under his leadership, The Alger Weatherbie Specialized Growth Strategy has achieved top performances in recent years, including being ranked #1 in the Mid-Cap Growth Category during the first quarter of 2019. George has been featured and quoted in a number of publications in leading journals such as New York Times, Investor’s Business Daily and Barron’s. He was also interviewed on Reuters Television. George received his MBA from the Wharton School, University of Pennsylvania (Director’s List), and his Ph.D. in chemistry from Johns Hopkins University. Previously, he earned a B.S. from the University of Science and Technology of China and was a pharmaceutical research scientist at Procter & Gamble. George is a prized Bridge player, and he holds four U.S. patents.

Peng Lin, Ph.D. J.D, Patent Attorney, Associate, Fish & Richardson
Peng Lin is a patent attorney at Fish & Richardson. He focused on his practice on worldwide patent procurement, patent portfolio management, and strategic planning for life sciences companies. He is currently helping several big Chinese pharmaceutical and biotech companies to develop their IP strategies. Peng received his J.D. cum laude from Harvard Law School, and his Ph.D. in Human and Statistical Genetics from Washington University in St. Louis. He was also named as a Kauffman Fellow for Bio-entrepreneurship at Washington University. Prior to graduate school, Peng earned his B.S. in Biological Science with high honors from Tsinghua University. In addition, Peng has also been actively involved in the management team of the Chinese Antibody Society since 2016. He is currently the vice president of Chinese Antibody Society.

Topics to cover: how to translate scientific findings to biomedical products; Keys to protect scientific discoveries by IP; Tips to attract private and public investment et al.

Look forward to meeting everyone tomorrow.

CALA

[Ke Yuan]

2021 CALA Happy Friday Seminar
Feb 19th, 2021

https://arizona.zoom.us/j/97032505774 (Password: 654321)
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Omics and Precision Medicine in Asthma

Dr. Juan C. Celedón, MD, DrPH, ATSF
Niels K. Jerne Professor
University of Pittsburgh
Division Chief of Pulmonary Medicine
UPMC Children’s Hospital of Pittsburgh

Dr. Juan C. Celedón is the ATS president for the 2020-21 term. Dr. Celedón earned a degree in medicine from Javeriana University in Colombia and a doctoral degree in public health from Harvard University. He completed a residency in Internal Medicine at Beth Israel Medical Center in New York, a Fellowship in Pulmonary and Critical Care Medicine at Brown University, and a Research Fellowship at the Channing Laboratory of Brigham and Women's Hospital and Harvard Medical School. In 2000, he joined the faculty at Harvard Medical School, rising to Associate Professor before joining the University of Pittsburgh in 2010.
Dr. Celedón's research has focused on asthma, COPD, and health disparities in airway diseases. His scientific contributions have been acknowledged through his election to the American Society for Clinical Investigation and the Association of American Physicians, as well as through the ATS Recognition Award for Scientific Accomplishments, among other honors. A devoted mentor, he was the first faculty member to ever receive both the Young Mentor Award and the A. Clifford Barger Excellence in Mentoring Award from Harvard Medical School.

[Ke Yuan]

2021 CALA Happy Friday Seminar
Feb 19th, 2021

https://arizona.zoom.us/j/97032505774 (Password: 654321)
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm

Omics and Precision Medicine in Asthma

Dr. Juan C. Celedón, MD, DrPH, ATSF
Niels K. Jerne Professor
University of Pittsburgh
Division Chief of Pulmonary Medicine
UPMC Children’s Hospital of Pittsburg