Can GLP-1 drugs slow ageing? Mouse study shows promise

[John Clark]

The following is from the September 2, 2026 issue of the journal Nature: 

"Animals treated with the GLP-1 drug semaglutide (marketed under the brand names Ozempic and Wegovy), had a median lifespan of 834 days — 12% longer than mice in the control group, which lived for a median of 742 days.Mice that took semaglutide also did better than control animals on tests that evaluated coordination, muscle function and how the body processes sugar. [...]  The mice taking semaglutide during the study self-reduced their calorie intake by 24%. So, to check whether this was the cause of the observed effects, the authors put an extra, untreated group of mice on a diet that matched the calorie-intake level of the GLP-1-treated mice. The two groups showed similar longevity outcomes. However, the GLP-1-treated mice performed better than did those in the diet group in several experiments, including one testing spatial memory, in which animals had to remember the location of the exit to a maze."

Can GLP-1 drugs slow ageing? Mouse study shows promise

John K Clark    See what's on my list at  Extropolis

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