Dear cBioPortal group,
I am exploring the expression of the TTK gene and TIMP3 gene in Uterine Corpus Endometrial Carcinoma (TCGA, PanCancer Atlas), trying to find:
1. whether those endometrial patients with high TTK expression would express less TIMP3.
2. whether TTK is overexpressed, while TIMP3 is downregulated in endometrial cancer tissues relative to normal tissues
Could you kindly please let me know the difference between:
1. mRNA expression z-scores relative to normal samples
2. mRNA expression z-scores relative to all samples
In my case, which one I should select?
Thank you so much for your help.
Peixin Dong, MD, PhD
Department of Obstetrics and Gynecology
Hokkaido University School of Medicine
Hokkaido University
N15, W7, Kita-ku, Sapporo, 0608638, Japan
Tel: +81-11-706-5941; Fax: +81-11-706-7711
E-mail: dpx...@med.hokudai.ac.jp; E-mail: dpx...@gmail.com
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