You can use the software (cleanflight) to start troubleshooting.
In cleanflight make sure that you can see when you adjust the controller.
Then with the blades off make sure you can control the motors with the software.
Other things to check:
You need to flip the switches back to flight mode. 1 and 2 on, 3, 4, 5, 6, off.
Make sure on the Configuration screen under ESC/Motor features MOTOR_STOP is not turned on.