AU pitch will only do it's machine gun thing if pitched down and feeding back. But if you aren't using it at the moment get rid of it.
From what you have said when you start the cue with all sliders down you have a stable system. As soon as you open a slider the instability happens. The first thing is to establish beyond any doubt that this is not acoustic feedback. Try unplugging the mic, and as a separate test setting the input on the mic cue to inf (i.e the left most column marked inputs under the master slider level box in device and levels).
If it still happens set up an identical FX chain in a normal audio cue (and replicate the cue output inserts in the audio rather than the mic settings). Is the system stable with that?
Are you sure you do not have anything in the system that could be connecting an output to an input?. Either a cable physically doing this on your interface as a loopback, a soft patch in soundflower, or an interface control panel that allows this.