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What did you do just prior to the weekend that changed anything?
Did you upgrade the Python installation you are dependent on, but not recreate the Python virtual environment against the updated Python installation?
Did you apply any update to the Apache version being used?
Did you change the Apache configuration to load any additional Apache modules?
Did you change the Apache configuration for any modules you were already using?
How many Python installations exist on the system and where are they installed?
What Python installation is your Python virtual environment based off?
What Python installation was mod_wsgi compiled against?
Is the mod_wsgi.so finding the correct Python shared library for the Python installation you expect it to use?
Are you using mod_wsgi daemon mode?
Is Apache segfaulting on startup in all child processes, or only for mod_wsgi daemon mode processes?
Is the segfault truly on startup, or only on the first request against a process?
Sorry for all the questions, but there isn't a lot to go on at this point.
The point of these questions is to prompt you to validate certain things about your installation and ensure they are correct, but responses to them will also help me to understand your setup and so be able to work out what the issue may be.
[Sun Jul 13 04:04:13 2014] [info] mod_wsgi (pid=5845): Attach interpreter ''.
[Sun Jul 13 04:04:13 2014] [info] mod_wsgi (pid=5845): Adding '/opt/vcweb' to path.
[Sun Jul 13 04:04:13 2014] [info] mod_wsgi (pid=5845): Adding '/opt/virtualenvs/vcweb/lib/python2.7/site-packages' to path.
[Sun Jul 13 04:04:14 2014] [info] mod_wsgi (pid=5854): Attach interpreter ''.
[Sun Jul 13 04:04:14 2014] [info] mod_wsgi (pid=5854): Adding '/opt/vcweb' to path.
[Sun Jul 13 04:04:14 2014] [info] mod_wsgi (pid=5854): Adding '/opt/virtualenvs/vcweb/lib/python2.7/site-packages' to path.
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