import-export selected gene sets in GSEA

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Mohsen Fathzadeh

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Jun 21, 2021, 7:13:28 PM6/21/21
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Hello GSEA team,

I have exported a list of 11 gene sets as .gmt and do not know how to import this file into GSEA for analysis. 
If I understood correctly, I need to install another application known as MSigDB XML Browser application to enable this feature.
Unfortuenly, I am not skillful with coding in MAC Terminal to install java 11 and/or could not troubleshoot/launch the MSigDB application. 
Any thoughts, feedback, and resources that help me through this would greatly be appreciated. 

Thanks,
Mohsen 

Anthony Castanza

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Jun 21, 2021, 7:14:51 PM6/21/21
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Hi Mohsen,

 

If you’ve already retrieved the gene sets as GMT files, you can load them in through the Load data panel in GSEA the same way you load in datasets. You do not need the XML browser.

Once you’ve loaded in the gene sets, they should appear in the “Gene matrix (local gmx/gmt)” tab in the Gene sets database dialogue.

 

-Anthony

 

Anthony S. Castanza, PhD

Curator, Molecular Signatures Database

Mesirov Lab, Department of Medicine

University of California, San Diego

http://gsea-msigdb.org/

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Mohsen Fathzadeh

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Jun 21, 2021, 7:23:09 PM6/21/21
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Hi Anthony, 

That’s fantastic! I could complete the analysis. Very nice program!! Thank you so much! 
Mohsen 



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