ohnf@Var2CSA:~/Downloads/bgal$ e2projectmanager.py
(python:28911): Gtk-WARNING **: Unable to locate theme engine in module_path: "hcengine",
NOT Writing notes, ppid=-2
Building initial averages
Making subset of ~2000 particles for initial averages
5513 images, processing 0-5512 stepping by 2
2757 images
Classify by k-means
2757 images to classify.
iter 0> 2673 (50)
iter 1> 2659 (50)
iter 2> 2307 (50)
iter 3> 2554 (50)
iter 4> 2306 (50)
iter 5> 2642 (50)
iter 6> 2404 (50)
iter 7> 2449 (50)
iter 8> 2340 (50)
iter 9> 1722 (50)
iter 10> 30 (50)
iter 11> 2484 (50)
iter 12> 2036 (50)
iter 13> 27 (50)
iter 14> 1898 (50)
iter 15> 1850 (50)
iter 16> 1920 (50)
iter 17> 9 (50)
iter 18> 11 (50)
iter 19> 1417 (50)
iter 20> 1422 (50)
iter 21> 1396 (50)
iter 22> 2310 (50)
iter 23> 357 (50)
iter 24> 2161 (50)
iter 25> 17 (50)
iter 26> 16 (50)
iter 27> 2253 (50)
iter 28> 12 (50)
iter 29> 9 (50)
iter 30> 11 (50)
iter 31> 8 (50)
iter 32> 459 (50)
iter 33> 2293 (50)
iter 34> 1479 (50)
iter 35> 9 (50)
iter 36> 10 (50)
iter 37> 9 (50)
iter 38> 2288 (50)
iter 39> 3 (50)
iter 40> 4 (50)
iter 41> 4 (50)
iter 42> 2269 (50)
iter 43> 4 (50)
iter 44> 2 (50)
0) ################################################### (61)
1) ################################################### (61)
2) ######################################################## (67)
3) ########################################## (50)
4) ############################################################# (73)
5) ############################### (37)
6) ######################################### (49)
7) ################################## (41)
8) ################################################################ (76)
9) ########################################################## (69)
10) #################################################### (62)
11) ########################################################### (70)
12) ######################################### (49)
13) ################################################# (59)
14) ####################################################### (66)
15) ################################################## (60)
16) #################################################################### (81)
17) ############################################ (52)
18) ################################################################# (77)
19) ######################################## (48)
20) ############################################# (54)
21) ################################### (42)
22) ################################################## (60)
23) ####################################### (47)
24) ######################################### (49)
25) ####################################################### (65)
26) ####################################### (47)
27) ##################################### (44)
28) ########################### (33)
29) ############################################# (54)
30) ############################################ (52)
31) ########################################## (50)
32) ########################################## (50)
33) ################################# (40)
34) ############################################# (54)
35) ########################################################## (69)
36) ################################################## (60)
37) ########################################### (51)
38) ########################################################### (70)
39) ######################################################################## (85)
40) ############################### (37)
41) ###################################### (45)
42) ############################################################ (72)
43) ####################################################### (65)
44) ########################### (33)
45) ################################# (39)
46) ################################ (38)
47) ########################################### (51)
48) ############################################# (54)
49) ################################# (39)
Class averaging beginning
Error running task : 34
Error running:
e2classaverage.py --input=r2d_02/input_subset.hdf --classmx=r2d_02/classmx_00.hdf --output=r2d_02/classes_init.hdf --iter=8 --force --bootstrap --center=xform.center --align=rotate_translate_tree:maxshift=14 --averager=ctf.weight.autofilt --keep=0.850000 --cmp=ccc --aligncmp=ccc --normproc=normalize.edgemean --parallel=thread:4
Any thoughts?
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Try switching to the "mean" averager and see if it still crashes. If it does, please provide the exact e2refine2d command-line you ran (from the 'command' tab in e2projectmanager, or from the .eman2log.txt file). You may also wish to try e2refine2d_bispec instead and see how that works (generally runs faster, and seems to produce superior results).
--------------------------------------------------------------------------------------
Steven Ludtke, Ph.D. <slu...@bcm.edu> Baylor College of MedicineCharles C. Bell Jr., Professor of Structural Biology
Dept. of Biochemistry and Molecular Biology (www.bcm.edu/biochem)Academic Director, CryoEM Core (cryoem.bcm.edu)
Co-Director CIBR Center (www.bcm.edu/research/cibr)
Co-Director National Center For Macromolecular Imaging (ncmi.bcm.edu)
On Mar 12, 2018, at 5:39 PM, jm...@psu.edu wrote:
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John M. Flanagan PhD.
e2refine2d_bispec.py --input=sets/all__ctf_flip_bispec.lst --ncls=32 --iter=3 --nbasisfp=8 --center=xform.center --classkeep=0.8 --classiter=4 --classalign=rotate_translate_tree:flip=0 --classaligncmp=ccc --classraligncmp=ccc --classaverager=ctf.weight.autofilt --classcmp=ccc --classnormproc=normalize.edgemean
(python:32138): Gtk-WARNING **: Unable to locate theme engine in module_path: "hcengine",
NOT Writing notes, ppid=-2
Building initial averages
WARNING: images in sets/all__ctf_flip_bispec.lst have the wrong dimensions. Recomputing bispectra. This will slow processing.
Starting thread 55/56
Classify by k-means
5513 images to classify.
iter 0> 0 (32)
reseed 1 -> 14
reseed 2 -> 5366
reseed 3 -> 2444
reseed 4 -> 2900
reseed 5 -> 1657
reseed 6 -> 1935
reseed 7 -> 2760
reseed 8 -> 479
reseed 9 -> 1477
reseed 10 -> 3382
reseed 11 -> 2132
reseed 12 -> 5022
reseed 13 -> 2543
reseed 14 -> 1069
reseed 15 -> 619
reseed 16 -> 5425
reseed 17 -> 1862
reseed 18 -> 1151
reseed 19 -> 5153
reseed 20 -> 949
reseed 21 -> 2340
reseed 22 -> 3729
reseed 23 -> 1717
reseed 24 -> 4890
reseed 25 -> 846
reseed 26 -> 3541
reseed 27 -> 5007
reseed 28 -> 2261
reseed 29 -> 2545
reseed 30 -> 4157
reseed 31 -> 522
0) ######################################################################## (5513)
1) (1)
2) (1)
3) (1)
4) (1)
5) (1)
6) (1)
7) (1)
8) (1)
9) (1)
10) (1)
11) (1)
12) (1)
13) (1)
14) (1)
15) (1)
16) (1)
17) (1)
18) (1)
19) (1)
20) (1)
21) (1)
22) (1)
23) (1)
24) (1)
25) (1)
26) (1)
27) (1)
28) (1)
29) (1)
30) (1)
31) (1)
Class averaging beginning
InvalidCallException at /home/eman2/anaconda2/conda-bld/eman2_1518620532721/work/libEM/aligner.cpp:2662: 'ERROR (RT2DTreeAligner): requires cubic images with even numbered box sizes' caught
Class averaging complete
Input file 'r2db_01/classes_00.hdf' does not exist.
Traceback (most recent call last):
File "/usr/local/bin/EMAN2/bin/e2proc2dpar.py", line 393, in <module>
main()
File "/usr/local/bin/EMAN2/bin/e2proc2dpar.py", line 112, in main
N=EMUtil.get_image_count(args[0])
File "/usr/local/bin/EMAN2/lib/python2.7/site-packages/EMAN2db.py", line 540, in db_get_image_count
raise Exception(fsp)
Exception: r2db_01/classes_00.hdf
Error running:
e2proc2dpar.py r2db_01/classes_00.hdf r2db_01/classes_fp_00.hdf --process math.bispectrum.slice:fp=10:size=32 --threads 4
Try switching to the "mean" averager and see if it still crashes. If it does, please provide the exact e2refine2d command-line you ran (from the 'command' tab in e2projectmanager, or from the .eman2log.txt file). You may also wish to try e2refine2d_bispec instead and see how that works (generally runs faster, and seems to produce superior results).
--------------------------------------------------------------------------------------
Steven Ludtke, Ph.D. <slu...@bcm.edu> Baylor College of MedicineCharles C. Bell Jr., Professor of Structural Biology
Dept. of Biochemistry and Molecular Biology (www.bcm.edu/biochem)Academic Director, CryoEM Core (cryoem.bcm.edu)
Co-Director CIBR Center (www.bcm.edu/research/cibr)
Co-Director National Center For Macromolecular Imaging (ncmi.bcm.edu)
On Mar 12, 2018, at 5:39 PM, jm...@psu.edu wrote:
e2refine2d.py --input=sets/all__ctf_flip_lp12.lst --ncls=100 --fastseed --iter=6 --nbasisfp=12 --naliref=5 --center=xform.center --simalign=rotate_translate_tree --simaligncmp=ccc --simraligncmp=dot --simcmp=ccc --classkeep=0.85 --classiter=5 --classalign=rotate_translate_tree --classaligncmp=ccc --classraligncmp=ccc --classaverager=mean --classcmp=ccc --classnormproc=normalize.edgemean
On Mar 12, 2018, at 5:39 PM, jm...@psu.edu wrote:
WARNING: images in sets/all__ctf_flip_bispec.lst have the wrong dimensions. Recomputing bispectra. This will slow processing.
Hmm,1) looks like you may have started processing with an older snapshot of EMAN2? If you see this:
WARNING: images in sets/all__ctf_flip_bispec.lst have the wrong dimensions. Recomputing bispectra. This will slow processing.
it implies you should rerun CTF autoprocessing, optionally with the "--outputonly" option (for speed)
2) something else funny seems to be going on. Can you tell me what box size you used when picking particles? Use the browser (e2display.py) and have a look in particles/ and see what dimensions the _fullres particles have...
--------------------------------------------------------------------------------------
Steven Ludtke, Ph.D. <slu...@bcm.edu> Baylor College of MedicineCharles C. Bell Jr., Professor of Structural Biology
Dept. of Biochemistry and Molecular Biology (www.bcm.edu/biochem)Academic Director, CryoEM Core (cryoem.bcm.edu)
Co-Director CIBR Center (www.bcm.edu/research/cibr)
Co-Director National Center For Macromolecular Imaging (ncmi.bcm.edu)
On Mar 12, 2018, at 6:00 PM, JOHN FLANAGAN <jm...@psu.edu> wrote:
Groups "EMAN2" group.
To post to this group, send email to eman2@go! oglegroups.com
Hmm,1) looks like you may have started processing with an older snapshot of EMAN2? If you see this:
WARNING: images in sets/all__ctf_flip_bispec.lst have the wrong dimensions. Recomputing bispectra. This will slow processing.
it implies you should rerun CTF autoprocessing, optionally with the "--outputonly" option (for speed)
2) something else funny seems to be going on. Can you tell me what box size you used when picking particles? Use the browser (e2display.py) and have a look in particles/ and see what dimensions the _fullres particles have...
--------------------------------------------------------------------------------------
Steven Ludtke, Ph.D. <slu...@bcm.edu> Baylor College of MedicineCharles C. Bell Jr., Professor of Structural Biology
Dept. of Biochemistry and Molecular Biology (www.bcm.edu/biochem)Academic Director, CryoEM Core (cryoem.bcm.edu)
Co-Director CIBR Center (www.bcm.edu/research/cibr)
Co-Director National Center For Macromolecular Imaging (ncmi.bcm.edu)
On Mar 12, 2018, at 6:00 PM, JOHN FLANAGAN <jm...@psu.edu> wrote:
Groups "EMAN2" group.
To post to this group, send email to eman2@go! oglegroups.com
Hmm,1) looks like you may have started processing with an older snapshot of EMAN2? If you see this:
WARNING: images in sets/all__ctf_flip_bispec.lst have the wrong dimensions. Recomputing bispectra. This will slow processing.
it implies you should rerun CTF autoprocessing, optionally with the "--outputonly" option (for speed)
2) something else funny seems to be going on. Can you tell me what box size you used when picking particles? Use the browser (e2display.py) and have a look in particles/ and see what dimensions the _fullres particles have...
--------------------------------------------------------------------------------------
Steven Ludtke, Ph.D. <slu...@bcm.edu> Baylor College of MedicineCharles C. Bell Jr., Professor of Structural Biology
Dept. of Biochemistry and Molecular Biology (www.bcm.edu/biochem)Academic Director, CryoEM Core (cryoem.bcm.edu)
Co-Director CIBR Center (www.bcm.edu/research/cibr)
Co-Director National Center For Macromolecular Imaging (ncmi.bcm.edu)
On Mar 12, 2018, at 6:00 PM, JOHN FLANAGAN <jm...@psu.edu> wrote:
Groups "EMAN2" group.
To post to this group, send email to eman2@go! oglegroups.com
You gave that option to e2ctf_auto ? I'm a little unclear as to the sequence you've followed now:- 288 is a reasonable box size, yes- bispectra are all 16x320 or 34x32x10, so sounds also fine- if --outputonly gives you problems, you can rerun e2ctf_auto without that option, it will take a little longer, but not so terribly much- if you get a crash in 2D or 3D refinement, please try switching to the "mean" averager and try again. If this solves the problem, it implies something is severely messed up in your CTF parameters, and you should check the fitting with the interactive interface (the tutorial describes this).
If it's still crashing, then please report again, and we can dig a little deeper.
--------------------------------------------------------------------------------------
Steven Ludtke, Ph.D. <slu...@bcm.edu> Baylor College of MedicineCharles C. Bell Jr., Professor of Structural Biology
Dept. of Biochemistry and Molecular Biology (www.bcm.edu/biochem)Academic Director, CryoEM Core (cryoem.bcm.edu)
Co-Director CIBR Center (www.bcm.edu/research/cibr)
Co-Director National Center For Macromolecular Imaging (ncmi.bcm.edu)
On Mar 13, 2018, at 10:03 AM, JOHN FLANAGAN <jm...@psu.edu> wrote:
Groups "EMAN2" group.
To post to this group, send email to eman2@! go! oglegroups.com
You gave that option to e2ctf_auto ? I'm a little unclear as to the sequence you've followed now:- 288 is a reasonable box size, yes- bispectra are all 16x320 or 34x32x10, so sounds also fine- if --outputonly gives you problems, you can rerun e2ctf_auto without that option, it will take a little longer, but not so terribly much- if you get a crash in 2D or 3D refinement, please try switching to the "mean" averager and try again. If this solves the problem, it implies something is severely messed up in your CTF parameters, and you should check the fitting with the interactive interface (the tutorial describes this).
If it's still crashing, then please report again, and we can dig a little deeper.
--------------------------------------------------------------------------------------
Steven Ludtke, Ph.D. <slu...@bcm.edu> Baylor College of MedicineCharles C. Bell Jr., Professor of Structural Biology
Dept. of Biochemistry and Molecular Biology (www.bcm.edu/biochem)Academic Director, CryoEM Core (cryoem.bcm.edu)
Co-Director CIBR Center (www.bcm.edu/research/cibr)
Co-Director National Center For Macromolecular Imaging (ncmi.bcm.edu)
On Mar 13, 2018, at 10:03 AM, JOHN FLANAGAN <jm...@psu.edu> wrote:
Groups "EMAN2" group.
To post to this group, send email to eman2@! go! oglegroups.com
e2refine2d_bispec.py --input=sets/all__ctf_flip_bispec.lst --ncls=64 --iter=3 --nbasisfp=8 --parallel=thread:16 --center=xform.center --classkeep=0.8 --classiter=4 --classalign=rotate_translate_tree:flip=0 --classaligncmp=ccc --classraligncmp=ccc --classaverager=ctf.weight.autofilt --classcmp=ccc --classnormproc=normalize.edgemean
NOT Writing notes, ppid=-2
--threads set to match --parallel
Building initial averages
WARNING: images in sets/all__ctf_flip_bispec.lst have the wrong dimensions. Recomputing bispectra. This will slow processing.
Starting thread 101/102
Classify by k-means
10118 images to classify.
iter 0> 0 (64)
reseed 1 -> 4056
reseed 2 -> 9824
reseed 3 -> 5385
reseed 4 -> 1418
reseed 5 -> 3538
reseed 6 -> 3087
reseed 7 -> 9
reseed 8 -> 7864
reseed 9 -> 7715
reseed 10 -> 9371
reseed 11 -> 1335
reseed 12 -> 6114
reseed 13 -> 5216
reseed 14 -> 8423
reseed 15 -> 584
reseed 16 -> 7771
reseed 17 -> 185
reseed 18 -> 734
reseed 19 -> 493
reseed 20 -> 7743
reseed 21 -> 4116
reseed 22 -> 7321
reseed 23 -> 6017
reseed 24 -> 6558
reseed 25 -> 8714
reseed 26 -> 1540
reseed 27 -> 6114
reseed 28 -> 755
reseed 29 -> 7142
reseed 30 -> 6438
reseed 31 -> 5932
reseed 32 -> 5866
reseed 33 -> 2505
reseed 34 -> 9865
reseed 35 -> 2777
reseed 36 -> 2932
reseed 37 -> 1588
reseed 38 -> 4958
reseed 39 -> 6622
reseed 40 -> 3795
reseed 41 -> 4087
reseed 42 -> 361
reseed 43 -> 5072
reseed 44 -> 4812
reseed 45 -> 5050
reseed 46 -> 3983
reseed 47 -> 4726
reseed 48 -> 2502
reseed 49 -> 1356
reseed 50 -> 4859
reseed 51 -> 9222
reseed 52 -> 7961
reseed 53 -> 5605
reseed 54 -> 4086
reseed 55 -> 1002
reseed 56 -> 4823
reseed 57 -> 6189
reseed 58 -> 4922
reseed 59 -> 571
reseed 60 -> 5679
reseed 61 -> 2033
reseed 62 -> 4052
reseed 63 -> 7784
0) ######################################################################## (10118)
32) (1)
33) (1)
34) (1)
35) (1)
36) (1)
37) (1)
38) (1)
39) (1)
40) (1)
41) (1)
42) (1)
43) (1)
44) (1)
45) (1)
46) (1)
47) (1)
48) (1)
49) (1)
50) (1)
51) (1)
52) (1)
53) (1)
54) (1)
55) (1)
56) (1)
57) (1)
58) (1)
59) (1)
60) (1)
61) (1)
62) (1)
63) (1)
Class averaging beginning
InvalidCallException at /home/eman2/anaconda2/conda-bld/eman2_1518620532721/work/libEM/aligner.cpp:2662: 'ERROR (RT2DTreeAligner): requires cubic images with even numbered box sizes' caught
Class averaging complete
Cleaning up thread server. Please wait.
Input file 'r2db_01/classes_00.hdf' does not exist.
Traceback (most recent call last):
File "/usr/local/bin/EMAN2/bin/e2proc2dpar.py", line 393, in <module>
main()
File "/usr/local/bin/EMAN2/bin/e2proc2dpar.py", line 112, in main
N=EMUtil.get_image_count(args[0])
File "/usr/local/bin/EMAN2/lib/python2.7/site-packages/EMAN2db.py", line 540, in db_get_image_count
raise Exception(fsp)
Exception: r2db_01/classes_00.hdf
Error running:
e2proc2dpar.py r2db_01/classes_00.hdf r2db_01/classes_fp_00.hdf --process math.bispectrum.slice:fp=10:size=32 --threads 16
You gave that option to e2ctf_auto ? I'm a little unclear as to the sequence you've followed now:- 288 is a reasonable box size, yes- bispectra are all 16x320 or 34x32x10, so sounds also fine- if --outputonly gives you problems, you can rerun e2ctf_auto without that option, it will take a little longer, but not so terribly much- if you get a crash in 2D or 3D refinement, please try switching to the "mean" averager and try again. If this solves the problem, it implies something is severely messed up in your CTF parameters, and you should check the fitting with the interactive interface (the tutorial describes this).
If it's still crashing, then please report again, and we can dig a little deeper.
--------------------------------------------------------------------------------------
Steven Ludtke, Ph.D. <slu...@bcm.edu> Baylor College of MedicineCharles C. Bell Jr., Professor of Structural Biology
Dept. of Biochemistry and Molecular Biology (www.bcm.edu/biochem)Academic Director, CryoEM Core (cryoem.bcm.edu)
Co-Director CIBR Center (www.bcm.edu/research/cibr)
Co-Director National Center For Macromolecular Imaging (ncmi.bcm.edu)
On Mar 13, 2018, at 10:03 AM, JOHN FLANAGAN <jm...@psu.edu> wrote:
Groups "EMAN2" group.
To post to this group, send email to eman2@! go! oglegroups.com