Normally I would say no but I'm working with Liferay in this case - an enterprise portal - so the Angular applications will live inside portlets which can be made to be instancable.
So, a use case would be:
A client wants a charts portlet where the data source is configurable - something that is possible through portlet configuration within the Portal/CMS UI - but for all intents and purposes the application in each instance would be the same app, but they might need to navigate independently. The client could drag their chart portlets, each containing a copy of the same Angular chart application, onto a page and then they would all operate independently.
This all isn't necessary but it would be nice if it were possible. I know you can have two copies of the same app running on a page, so it would, or should, follow that it is also possible for them to navigate independently.