Spencer.
As per Jon's post - there is a little arrow at the bottom of the glass envelope that helps to determine the polarity of he IN-3s. Arrow points to the cathode. Details are on the data sheet (in rRussian) on Dieters web site as to which is cathode and which is the anode.
Did you measure the strike and maintain voltages of the IN-3? I've found wide variations in strike and maintain voltages even within the same box of 100 tubes. Typical operation in the data sheet is 0.8ma with a low of 0.2ma and a high of 1ma. If your IN-3s maintaining voltage is at spec (55v), then by my maths you are dropping 125v over the 220k anode resister which is a 0.5ma current. This is within tolerances but on the low side.
I have tubes that have maintaining voltages as low as 36v and some other are as high as 70v. If you run the math you will find that you can lower the anode resister to 180K, and even lower for tubes with higher maintaining voltages (probably best not to go below 150K!). I try and run all of my IN-3s as close to the 0.8ma spec as possible - but this is for consistency in a ring circuit where I am also trying to get all of the tubes strike/maintain voltages aligned. Note even at 0.9 to 1ma I still got flicker and coverage variations in some tubes, but higher current did help with getting full plasma coverage.
My own experience is that some IN-3s flicker and the plasma can even form at the back rather than the front of the tube before returning to the front again. I have also had bulbs where the plasma forms on the wire lead at the bottom of the tube. In some applications the flickering is endearing, it others, such as ring circuits its down right annoying negating the circuit. Like John S, I've also aged my IN-3s and it does not seem to make much difference - there are always some that just want to flicker. If you age the IN-3s then after a couple of hours these "flickering" ones will become visible to you. Having said this I have aged IN-3 with a couple hundred hours of ring circuit use that decided to flicker and become unreliable - go figure. From what I have observed, increasing the strike voltage or (minor) current changes has no impact, but higher current do get better glow coverage. There also appears to be no correlation when it comes to flicker between the strike and maintaining voltage differences between tubes. Having said this beware of tubes which have a high strike and maintain voltages as from examination I often found these to have some visible internal physical variation to a "normal" IN-3 and of course they were no good for a ring circuit. From aging several hundreds of these IN-3s and building 2 ring-counter clocks, to me it just looks like there are differences in the manufacture between tubes. IN-3s look to have wide tolerances between and within the same box. Ive discarded 80% of some boxes and less than 10% of others due to variations in performance - but again this is for ring circuits.
In your application you are using the IN-3 as a colon separator. If it worries you replace it. If not you can call it an extra feature. One of my fellow workmates really likes the flickering of one lock I have at work, which takes the form of the plasma pulsing, she says it has personality.