NYTimes.com: We Can Cure Disease by Editing a Person’s DNA. Why Aren’t We?

[John Clark]

Check out this article from The New York Times. Because I'm a subscriber, you can read it through this gift link without a subscription.

We Can Cure Disease by Editing a Person’s DNA. Why Aren’t We?

Revolutionized medicine may be at hand, but barriers remain.

https://www.nytimes.com/2022/12/09/opinion/crispr-gene-editing-cures.html?unlocked_article_code=1nwN6waTon3bLMgzkRIIvYN1kb0ChYJG0NRwHAWyNKec0GCPUxSNm4I-8XhlACBPWNuOJr1Kzm9nSuoBT7A19srKYs6JFjP3ELOtu_oaB3IRAA9ZZnO2AqAP0YzQfyacYNH4lYhSMZ4pI_KjzZcO37Le-_7gnGM_gBqE0cyKIzvApWVjUeXpJE1FdJ10r4zx5ntfmHflxaG3XmdNWgnK-M4pRWx_OM4ZWzTRRuPRsFXhD-eIL-e242uP8QChtPq9Ax5OQd2K-dwHp_YZS-SaU5qlEtlOBVmSosB5MM4wRQ0tbJbDhJlmcXE1MFAUuHD3pWAb9Saz51mwoxN9_9RK0R3FjQ&smid=em-share

[spudb...@aol.com]

We haven't pushed it. I asked my B-in-law some years ago about Crispr-Cas9 and whether it would have any use for curing diseases even non-genetically expressed or caused. He was a chemotherapist and a palliative care guy, and cautiously, he considered that it wouldn't. Wrong!!! I'd have been throwing cash at this, as well as tissue engineering, artificial wombs, you know the drill? That's my policy as a serf in this plutocracy that has us. There is a lot of damage had we rushed blindly into Cas-9 and a bunch of dead patients, but, o' course, using AI-pharma systems on Body Maps would have been 1st on the list of testing, before any animal study. 

The elites aren't so much better than us, me thinks.

Nice article and thanks, JC.

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[Lawrence Crowell]

There are all sorts of questions this brings up. I suppose it is inevitable, but it could redefine what is meant by being human. Human beings could end up as engineered beings for various purposes.

LC

[spudb...@aol.com]

All true. Now it is a disturbing thing, but then so its nuclear annihilation, which has been of real concern, once more, since February of this year. So, being adults here we suck it up, and when we deal with the ethical troubles that tech presents, we should also joyfully enjoy it's benefits.

By the by, astrophysicist and science fiction writer Alastair Reynolds has written of this issue with The Pigs. Yes, a merger of the anthropoid and the porcine. They, being lab produced and then set loose in other solar systems, they are interlaced with our species with commerce and travel. Chasm City (not Mars) is one of these worlds. Reynold's 'worlds' are mostly interstellar, mostly set ages from now where human civilizations rises for ages, the fall, and rise again, across the Milky Way ant speeds below that of light. 

Chasm City - Wikipedia

Hyperpigs | Revelation Space Wiki | Fandom

This is not a problem I expect anytime soon. So back to planet earth, we need to cure disease and get better energy and transportation (EV's) in place, while avoiding nuclear death with Putin and Xi. Our task at hand....

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[John Clark]

On Sat, Dec 10, 2022 at 2:49 PM Lawrence Crowell <goldenfield...@gmail.com> wrote:

> There are all sorts of questions this brings up. I suppose it is inevitable, but it could redefine what is meant by being human. Human beings could end up as engineered beings for various purposes.

It's evolve or die, on average species only last about 5 million years and I think biological humans will not come anywhere close to that figure and have less than a century left, perhaps only a decade or two. In just in the last year new developments in AI are coming so quickly it's hard to keep up; this is the most astounding artificial intelligence yet:

Flamingo, DeepMind's New AI

John K Clark    See what's on my new list at  Extropolis

fla

[spudb...@aol.com]

Cap'n Bloodwynn Pigg (space pirate)  at yer Cervix, me hearties! I did this one 2 weeks ago. Inspired by Alastair Reynolds. Let's see what Musk does with his Neralink 1st though?

-----Original Message-----
From: John Clark <johnk...@gmail.com>

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[Brent Meeker]

When a vaccine for polio was developed by Salk, a lot testing and red tape was cut because of the widespread public fear of the disease.  It still took more than a year to get it out.  But these bespoke CRISPR treatments should be able to accept a lot more risk of accidentally killing one person, that a nation wide vaccine program which would risk killing millions of people.

Brent

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[Lawrence Crowell]

On Saturday, December 10, 2022 at 2:46:58 PM UTC-6 johnk...@gmail.com wrote:

On Sat, Dec 10, 2022 at 2:49 PM Lawrence Crowell <goldenfield...@gmail.com> wrote:

> There are all sorts of questions this brings up. I suppose it is inevitable, but it could redefine what is meant by being human. Human beings could end up as engineered beings for various purposes.

It's evolve or die, on average species only last about 5 million years and I think biological humans will not come anywhere close to that figure and have less than a century left, perhaps only a decade or two. In just in the last year new developments in AI are coming so quickly it's hard to keep up; this is the most astounding artificial intelligence yet:

I rather doubt CRISPR or AI technology or much else is going to do a lot to enhance our survival. Humans have assumed a purpose of converting everything we can get our hands on into trash. During the administration of Bolsonaro in Brazil a total area of Amazon rain forest equal to Kansas was destroyed. We are 8 billion ground apes exponentially rampaging out of control. That is what will kill us, and in the rather near future. AI systems that can generate word strings, or pseudo-art and so forth will have little or no influence on saving Homo sapiens from themselves. 

LC