For this atlas, I first masked the background in atlas's average using the
atlas's mask using O4.
Then I got the edge image from the atlas label in O4 and also the edge
image of CIVM QA for further edge-based nonlinear registration.
Then, I wrapped atlas's edge image to that of the CIVM QA at O7
nonlinear registration, with the masked atlas image and CIVM ISO added
as additional volume to help normalization. The smoothing is increased
to 0.6. Once done, I applied the wrapping to the original label image.
I also applied several rounds of smoothing in O4 to the atlas label image
before all these steps because the boundary is not smooth.
Wish I can provide a standard tutorial, but the same strategy may not
work for other atlases. I usually try different approaches and
evaluate which is the best, and sometimes I have to modify DSI Studio
and open up new functions to enable certain features.
Frank
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