CLIQUE Problem

[Ankush Sharma]

Regards all,

I'm trying to run Hubba plugin to get hub nodes in the graph. Hubba is not computing the results which is most probably due to clique problem . The error displayed is " system cannot process a network contains a clique whose size is larger than 100" .  Is their any solution to this problem or any suggestion for other plugin which can determine hub proteins


Thanks in advance
Ankush Sharma

[piet molenaar]

Hi Ankush,
This is a problem of the plugin itself, you'd probably best contact the developers of the plugin; they have a contact form on their website: http://hub.iis.sinica.edu.tw/cytoHubba/contact.html
Hope this helps,
Cheers,
Piet

Ankush Sharma

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Piet Molenaar
piet...@gmail.com
Department of Oncogenomics, M1-131
Academic Medical Center
University of Amsterdam
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tel (+31) 20-5666592
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[Ankush Sharma]

HI Piet ,


Thanks for the concern, I wrote to them about the problem and  waiting for their reply

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Regards
Ankush Sharma

PhD in Computational Biology

Second University of Naples & Centro Ricerche Oncologiche
di Mercogliano

Email ID : ankush...@unina2.it


                                                   

[piet molenaar]

In the mean time a simple approach might be to use a topology filter and look for nodes having a large number of neighbours...
Cheers,
Piet

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[Ankush Sharma]

Hi ,

Many thanks for response. Actually there is high degree of assortativity associated with protein Interaction network. i wanted to confirm rich clubness in the networks by checking the interconnectivitybetween the hub proteins in the network . 

[Yamuna Shukla]

Hello Ankush,

Have you resolved the matter of this problem. I am also facing the same issue.
Please let me know if any successful solution you have found.

Thanks & regards,

Yamuna