High Tech Detox or LOW TECH-- Glutathione
randall
To detox or NOT that is the question.
Are you FULL OF it?
I just said:
in my last thread:
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/browse_thread/thread/686a015694613748?hl=en#
or
http://groups.google.com/group/alt.support.skin-diseases.psoriasis/msg/77153274cbd6e22b
Subject: Do HEALTH CARE MATH 101 - YOU'RE REsPonsible FOR YOU
**I also use NAC when necessary and resveratrol daily
(www.longevinex.com).**
And I mentioned Mother Nature and Nurture.
And also mentioned NAC for the nurture PART.
I'm BIG on NAC to create usable glutathione in your SYSTEM.
It's the best way to detox some crap OUT of YOU.
WE eat way to much CRAP and then we're FULL of it.
Which takes me back to my crap posts. LOL
OK, not now. i'm off the crap Throne and being EGO testiCOW for right
NOW.
In another minute or so ----> those BETs are off. <W>
I'm such a but wiPe... LOL
------
Back to cRAP...
The VRP folks have a cool looking new supplement designed to
enhance absorPtion of glutathione to detox **it.
http://www.vrp.com/articles.aspx?ProdID=art2832&zTYPE=2&search_in=articles
Single-Nutrient Protection for Living in a Toxic Modern World
Health News
By VRP Staff
Let’s face it: We live in a toxic world. Heavy metals… drugs…
radiation… pesticides… all of these dangerous toxins can become
trapped in your body, where they wreak havoc on your health over the
course of days, months, even years. And chances are good you come into
contact with at least one of them every single day—in the air that you
breathe, the water that you drink and the food that you eat.
The bad news? Short of living in a plastic bubble there’s no way to
avoid completely the daily exposure to this long list of dangerous
environmental pollutants. The good news, however, is that your body
actually produces one of your strongest sources of antioxidant
protection—in the form of a single tripeptide called
____glutathione._____
While vitamins C and E tend to monopolize the antioxidant spotlight,
glutathione’s ability to interact with enzymes means that it’s a more
reliable natural detoxifier. In fact, you’ll find its most
concentrated stores are in your liver—your body’s filter—where it will
bind with heavy metals and other toxins, allowing them to be safely
excreted.1-2 In its active (or “reduced”) form, glutathione is also
able to donate electrons that neutralize your body’s rogue free
radicals—while lower ratios of active glutathione are a key indication
of oxidative stress, a condition that paves the way to a long list of
degenerative diseases and illnesses.
Coronary artery disease, atherosclerosis and other heart problems, for
example, are linked to significant systemic declines in glutathione,
even in healthy adults—while asthma is similarly linked to localized
deficits.3-5 Conditions marked by excess oxidative stress, like
diabetes, can contribute to glutathione deficiencies—and lower levels
of this powerful antioxidant are also connected to Alzheimer’s
disease, autism and even increased susceptibility to seasonal flu
infection.6
With tens of thousands of published studies on its side, there’s no
question that a high-quality glutathione supplement can be a literal
lifesaver—especially in today’s toxic modern world. And thanks to
recent developments, getting daily doses of this key antioxidant in
its most reliable and active form is simpler now than ever.
Scientists have discovered a way to protect glutathione inside a tiny
lipid bubble called a liposome. A recent study suggests that liposomes
can help glutathione to remain more stable and available to your cells.
7Because liposomes are made out of the same material as your cell
membranes, liposomal glutathione ensures more rapid uptake and
availability of glutathione for your cells—and that means higher
levels of the “reduced” form of this powerful antioxidant will be
fighting free radicals and toxins in your body on a daily basis.8 You
can find this cutting-edge supplement in a product called
LipoCeutical™ Glutathione, available now through Vitamin Research
Products.
References:
<sniP>
===============
And if this high tech suPPlement is to expensive.
Broccoli isn't.
So start choPPing broccoli like on SNL.
Dava Carvey choppin
http://www.youtube.com/watch?v=Q1-yWIJi-gg
----------
255 hits for keywords: glutathione broccoli [on pubmed]
http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=DetailsSearch&term=glutathione+broccoli&log$=activity
88.158 returns for glutathione [pubmed]
http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=DetailsSearch&term=glutathione&log$=activity
Now that is choppin...
randall... OK ego leggo my EGGO....
jay
My Mom's sister has psoriasis. My Mom had cancer. And I have some GI/
immune system issues including vitiligo. When I eat brassica veggies,
they cause pain in my nerves. Possibly because their own natural
pesticide are quite strong (Brassica veggies routinely have the least
pesiticide levels).
I am wondering if people with psoriasis are genetically deficient in
their ability to handle ROS at cellular level. Then some challenge (ie
a bacterial infection, antibiotics, POPs, stress, etc) exceeds their
capacity and results in damage to cellular genetic material in a
manner similar to cancer where the abberant cells don't commit
apoptosis and continue to propogate. Do some studies support of refute
this line of thinking?
randall
Jay,
Whose on first?
Or is that who's on 1st iirc?
YOUR Moms Sister has a Th1 skew and your Mom has a Th2.
What do you DO?
Supplement and experiment or find the CAUsE of both situations and
then TREAT?
As to strictly Th1 cellular toxicity, I'd suspect little to zero
problems unless your phase II detox is out
of wack.
Which brings up CYP450
http://en.wikipedia.org/wiki/P450#P450s_in_humans
Which is why i try to keep folks at a minimum concerned about it.
Yet severe psoriatics most likely add to their skewy Th1 situation by
not
taking a gram or so every other day of NAC.
Same with the far skewed cancerous Th2 folks:
http://en.wikipedia.org/wiki/Acetylcysteine
And in which case you can skiP the brassica. My favorite being
the mustard. Yet i've enjoyed recentlly the effects of capers
(quercetin) and
apigenin or luteolin rich veggies
Celery being high on that list:
http://en.wikipedia.org/wiki/Quercetin
But ROS can be due to internal or external radiation.
The extreme would be living next to Chernobyl in which
case glutathione supplementation (NAC) would be Rx
http://en.wikipedia.org/wiki/Glutathione#Supplementation
Yet with anti ROS oral or ___topical___ supplementation your still
only playing with
a fraction of the equation.
A 1/2 or a 1/3 rd i won't quibble or eat supplemental kibble. LOL
But MY math adds up for ME. <W>
And using one to lever the other seems like childs play on a Ai teeter
totter to me.
Yet that is the state of modern medicine.
While present day scientists are unwittingly and slowly proving my
garden of eden (not eating --as proper dietary regimens will create
good gut flora and immune homeostasis) theory, they still can't see
the forest from the tree's let alone
the beneficial and health restorative effects of lacti loving gut
bacteria.
[Unless my current L. Plantarum study/trial does prove without a doubt
some day that
the Th17--> TH22 subsets are caused by excessive SFB, segmented
filamentous bacterium
in the ileum due to a alkaline colon instead of a slightly acidic one
full of lacti loving gut flora).
Let's look at dermatological meds and protocols and forget
the biologicals (TNF blockers) for a minute.
http://en.wikipedia.org/wiki/Calcitriol
Topical calcitriol works till you stop using it. :(
So?
Is it due to D3 then?
I can eat D3 all day long and at some point i get the oPPosite effect.
http://en.wikipedia.org/wiki/Vitamin_D3
http://en.wikipedia.org/wiki/Ultraviolet#Vitamin_D
VDR + autoimmune 75 returns [pubmed]---
http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=DetailsSearch&term=vdr+autoimmune&log$=activity
So?
Well...
Do the marshal protocol folks ( Marshall TG, Blaney GP, Albert PJ,
Proal AD) have
a secret up their sleeves other then vdr agonistical olmesartan?
Or do they own stock in the benicar folks daiichi sankyo?
http://en.wikipedia.org/wiki/Olmesartan
www.ncbi.nlm.nih.gov/pubmed/19758226
Reversing bacteria-induced vitamin D receptor dysfunction is key to
autoimmune disease.
Waterhouse JC, Perez TH, Albert PJ.
Autoimmunity Research Foundation, Thousand Oaks, California 91360,
USA. j...@autoimmunityresearch.org
Vitamin D research is discussed in light of the hypothesis that the
lower average levels of vitamin D frequently observed in autoimmune
disease are not a sign of deficiency. Instead, it is proposed that the
lower levels result from chronic infection with intracellular bacteria
that dysregulate vitamin D metabolism by causing vitamin D receptor
(VDR) dysfunction within phagocytes. The VDR dysfunction causes a
decline in innate immune function that causes susceptibility to
additional infections that contribute to disease progression. Evidence
has been accumulating that indicates that a number of autoimmune
diseases can be reversed by gradually restoring VDR function with the
VDR agonist ____olmesartan____ and subinhibitory dosages of certain
bacteriostatic antibiotics. Diseases showing favorable responses to
treatment so far include systemic lupus erythematosis, rheumatoid
arthritis, scleroderma, sarcoidosis, Sjogren's syndrome, autoimmune
thyroid disease, psoriasis, ankylosing spondylitis, Reiter's syndrome,
type I and II diabetes mellitus, and uveitis. Disease reversal using
this approach requires limitation of vitamin D in order to avoid
contributing to dysfunction of nuclear receptors and subsequent
negative consequences for immune and endocrine function.
Immunopathological reactions accompanying bacterial cell death require
a gradual elimination of pathogens over several years. Practical and
theoretical implications are discussed, along with the compatibility
of this model with current research.
PMID: 19758226
While Richard GAllo is now employed by the NPF to study pamps,
cathelicidins (LL37 or LL-37) and
downstream effects of natural antibiotics
http://en.wikipedia.org/wiki/PAMPs
I will bet it only proves what i've been saying about LPS since 2001
when JSTERN provided
the link to endogenous endotoxins and possible toxicities for innate
and adaptive immunity.
It's only the set UP for the current Th1, Th17 and Th22 subsets. Yet
or BUT due to WHAT?
SFB?
Did i say that before or only just NOW? LOL
With work like this
www.ncbi.nlm.nih.gov/pubmed/19966777
What's NOT to LIKE?
In this atopical case the microflora is in the SKIN.
Richard Gallo on page 29 of 35 in this NPF pdf:
http://www.psoriasis.org/NetCommunity/Document.Doc?id=548
back to el SOL....
Is it possible that while summer sunshine does help create high D3
levels, the
immune lowering effects of radiation (uvb's) are just as potent?
Yet you don't WANT to dePlete all of your glutathione in that process
either.
Topical calcitriol does suppress immunity without the rays:
www.ncbi.nlm.nih.gov/pubmed/19758324
Is the game thereby to only suppress Ai in plaques and business as
usual for the rest
of the bodies immunity?
Seems wack does it not?
Shall we aim the uvb 308 nano meter bean only at the psor plaque?
www.ncbi.nlm.nih.gov/pubmed/17934935
How does one create immune police so psorely needed in plaques?
Are TREGs designed to slow autoimmune in conjunction with vDR's?
tolerogenicity
http://medical-dictionary.thefreedictionary.com/tolerogenic
www.ncbi.nlm.nih.gov/pubmed/19405173
May 2009
Dendritic cell tolerogenicity: a key mechanism in immunomodulation by
vitamin D receptor agonists.
Adorini L, Penna G.
Intercept Pharmaceuticals, Perugia, Italy.
LAdo...@interceptpharma.com
Dendritic cells (DC) induce or tolerize T cells, and tolerogenic DCs
can promote the development of regulatory T cells (Treg) with
suppressive activity. Thus, the possibility of manipulating DCs and
enhancing their tolerogenic properties using different pharmacologic
or biologic agents could be exploited to control a variety of chronic
immuno-mediated inflammatory conditions. Among agents able to promote
induction of tolerogenic DCs, vitamin D receptor (VDR) agonists have
attracted considerable attention, also because of their potential in
clinical translation. DCs are key targets for the immunomodulatory
effects of VDR agonists, which shape DC phenotype and function,
enhancing their tolerogenicity in adaptive immune responses.
Tolerogenic DCs induced by a short treatment with VDR agonists promote
CD4+CD25+Foxp3+ Treg cells that are able to mediate transplantation
tolerance and to arrest the development of autoimmune diseases. VDR
agonists not only favor induction of CD4+CD25+ Treg cells, but can
also enhance their recruitment at inflammatory sites. The tolerogenic
properties induced by VDR agonists in DCs, leading to enhanced Treg
cell development, likely contribute to the beneficial activity of
these hormone-like molecules in autoimmune disease and graft rejection
models, highlighting their applicability to the treatment of chronic
inflammatory conditions sustained by autoreactive or alloreactive
immune responses.
PMID: 19405173
So is it a SNP with VDR or coming from uPstream as my gut (permeable
or permeation or
LEAKY works) theory calls for?
----
www.ncbi.nlm.nih.gov/pubmed/19818218
Acta Dermatovenerol Croat. 2009;17(3):187-92.
Vitamin d endocrine system and psoriasis vulgaris - review of the
literature.
Rucević I, Barisić-Drusko V, Glavas-Obrovac L, Stefanić M.
Ivana Rucević, MD, PhD Private Practice in Dermatology and
Venereology, Skolska 2, HR-31000 Osijek, Croatia; ivana.rucevic2@os.t-
com.hr.
Vitamin D exerts its physiological functions on calcium and bone
metabolism in humans through the active metabolite 1,25-
dihydroxyvitamin D3(1,25(OH)2D3). The other spectrum of vitamin D
activities includes important effects on cellular proliferation,
differentiation and the immune system. These effects are mediated
through the intracellularly located vitamin D receptor (VDR). VDR is a
member of the steroid, estrogen and retinoid receptor gene family of
proteins that mediate transcriptional activities of the respective
ligands. The VDR complex binds in the nucleus to the vitamin D
responsive element on the gene. Several polymorphisms of the vitamin D
receptor (VDR) gene have been described including FokI in exon 2, BsmI
and ApaI in intron 8 and TaqI in exon 9. Alterations in vitamin D-1,25
(OH)2D3 levels and polymorphisms of VDR gene have been shown to be
associated with several malignant or autoimmune diseases such as
sclerosis multiplex, breast cancer, diabetes mellitus, malignant
melanoma, and __psoriasis__ vulgaris. The effects of VDR gene
polymorphisms including immunomodulation, stimulation of cellular
differentiation and inhibition of proliferation make it a possible
candidate for therapy of psoriasis as well as for the psoriasis gene
modification. The objective of this article is to present the state-of-
the-art in the VDR gene polymorphism research in psoriasis vulgaris.
PMID: 19818218
Vitamin D receptor gene polymorphisms, particularly the novel A-1012G
promoter polymorphism, are associated with vitamin D3 responsiveness
and non-familial susceptibility in psoriasis.
Halsall JA, Osborne JE, Pringle JH, Hutchinson PE.
Department of Cancer Studies and Molecular Medicine, University of
Leicester, Leicester, UK. ja...@leicester.ac.uk
Psoriasis is a genetically determined disease characterized by
hyperproliferation and disordered maturation of the epidermis. Th1
lymphocytes are implicated in its pathogenesis. The vitamin D receptor
(VDR) is a candidate modifying gene, having immunosuppressive effects
and being involved in anti-proliferative and pro-differentiation
pathways in keratinocytes. There is suggestive evidence that the A
allele of the A-1012G polymorphism is associated with down-regulation
of the Th1 response, via GATA-3. The F and T alleles of Fok1 and Taq1
have been associated with increased VDR activity. The present study
aimed to test the hypothesis that the A allele of A-1012G is
protective for occurrence and severity of psoriasis and enhances
therapeutic response to vitamin D analogues and that these effects
would be additive to those of Fok1 and Taq1. The study group comprised
206 psoriasis patients who had received topical calcipotriol treatment
and 80 controls. There was no significant linkage disequilibrium
between any pair of the three polymorphic sites (P=0.3-0.8). The A, F
and T alleles were positively associated with calcipotriol response:
AA genotype (compared to AG/GG), odds ratio (OR)=2.18 (P=0.04); TT,
OR=1.97 (P=0.03); AAFF genotype combination, OR=4.11 (P=0.03); AATT,
OR=5.64 (P=0.005); and FFTT, OR=3.22 (P=0.01). Comparing patients
without, to patients with, a family history of psoriasis, the A allele
was under represented (P=0.01) and the AAFF genotype combination even
more so (compared to residual genotypes) (OR=0.24; P=0.005). AAFF was
also under-represented in patients without a family history compared
to controls (OR=0.31; P=0.04). There were no associations of family
history with Fok1 and Taq1. There were no associations of severity of
psoriasis with any polymorphism. In conclusion, the A-1012G, Fok1 and
Taq1 VDR polymorphisms were associated with response to calcipotriol.
A-1012G and Fok1 were associated with susceptibility to non-familial
psoriasis.
PMID: 15864137
But, but, but the leaky GUT (A garden of eden with broken leaky
sewers- LOL) works a Th1 skew via LPS (cell wall of endotoxin) has
been
established.
So what proof does one need beyond that?
Simply do the wit kit and block the leaky gut and see if you don't
simply clear uP?
What else is there?
The monkey wrench in the worx's is LPS.
And no amount of TNF blockers will STOP it forever.
So?
STAY on maBs to block TNF or cure the GUT?
Take your pick.
Here's a guy doing a promo for anti-TNF.
Ask yourself if the media does not become the willing accomplice of
BIG PHARMA?
Which is reminiscent with the last two american presidents and the
media.
Good or BAD your choice?
http://www.thetelegram.com/index.cfm?sid=312230&sc=85
Finally comfortable in his own skin
New psoriasis treatment gives Andrew Gosse his life back
BY DAVE BARTLETT
The Telegram
There’s a spot under Andrew Gosse’s fingernail, almost unnoticeable
unless he points it out.
But for Gosse, it’s a reminder of how his life has changed drastically
since he started taking a new medication for plaque psoriasis about
three years ago.
It also reminds him that his psoriasis will come back if he stops
taking the medication.
Gosse, a realtor from Paradise, is candid when he talks about the
things he’s gone through since being diagnosed at 17.
Though there’s no cure, he’s currently in the midst of a five-year
drug trial that he calls “a very effective control” for the autoimmune
skin disease.
“I’ve done a couple of drug trials with what they call biologics,
which is the new generation of drugs,” Gosse said in a recent
interview with The Telegram. “The one I’m on now, I’ve been on for
three years and it’s completely given me my life back.”
When it was bad
For most of his adult life, Gosse has lived with psoriasis and, at
times, the scaly red patches covered up to 38 per cent of his body.
But it all started with a small silver-white patch on his elbow.
When his doctor told him what it was and that he’d have it for the
rest of his life, Gosse said he had no idea what was in store.
“Over the next year to a year and a half it absolutely decimated my
body, head to toe,” Gosse said.
He remembers the big red blotches covering his forehead, eyebrows,
eyelashes, face, torso, legs, and “below the equator.”
If the effect on his appearance was bad, the itch was worse.
“I have, countless times, scratched myself so much and so
vigorously ... throughout the workday that when I got home I actually
had to brace myself to pull off my socks because blood had soaked out
through, and of course crusted, so you’re tearing off skin and flesh
and hair,” he said.
The itch was equally bad at night.
Gosse said he used to sleep with a comb next to his bed, which he
would use to scratch his body, and then pour vinegar on the affected
areas, just to get some sleep.
“You can sleep with the sting, you can’t sleep with the itch,” he
said.
After about two years, he became a patient of St. John’s dermatologist
Dr. Wayne Gulliver.
“By the time I made it to Dr. Gulliver, (the psoriasis) was so thick
on my head and other parts of my body, I could take a fork, (stick it
in a patch) and couldn’t feel it.”
What he’s tried
Gosse said psoriasis sufferers will often try just about anything to
control the condition or relieve the itch.
“I’ve gone through the years (with) the baths and the creams and the
lotions,” he said.
He’s also tried a number of “crazy” treatments, from diets to shark
cartilage and seal oil, and walking around wrapped up in plastic wrap.
When asked what the craziest treatment he tried was, Gosse laughed and
said it wouldn’t be printed in the paper.
But as an example, he said one diet — nothing but green peas and wild
rice — left him 40 pounds lighter and no better off.
“What you’ve got to understand is the desperation (psoriasis) causes,”
he said. “It’s unbelievable what you’d do just to get some relief, let
alone an effective control.”
After he became a patient of Gulliver’s, Gosse started getting treated
institutionally.
He said Gulliver’s “continual drive and investigation, and keeping me
as a patient informed,” led to all sorts of other treatments, from
special baths to drug trials.
“(Gulliver) offered whatever was out there and was honest about the
chances and length that treatments may work,” Gosse said.
Hiding it
While the physical part of the disease is difficult to deal with, he
said the hardest part of living with psoriasis is the psychological
part, which is not normally talked about.
Some people, he said, turn to drugs or alcohol to deal with the
stress. Others hide in the shadows and withdraw from their social
circles.
“Anybody who’s had severe or even moderate plaque psoriasis ... knows
exactly what I’m talking about,” said Gosse.
He said people start by trying to hide the red patches under clothing,
long hair or glasses.
When asked how his friends reacted to his condition, Gosse said barely
anyone outside of a close circle of friends had any idea he had
psoriasis.
“Even people that knew me very well would say they had no idea because
I spent so much energy trying to hide it,” he said.
He said his neighbours must have thought he was cracked when he would
be mowing his lawn in July with a turtleneck on in 27 C heat.
“But if I had taken my shirt off, people would have taken their
children off the street,” Gosse said.
Luckily, the worst of it was on Gosse’s hands under his fingernails,
and while painful, he was able to conceal it under bandages.
New treatment
Then three years ago, Gulliver asked Gosse to try the new biologic
drug that he’s still on.
At first, he didn’t have a lot of hope, but as always, he was willing
to try anything.
While everything he tried before treated psoriasis from the outside,
the biologics treat his condition from the inside.
Now he simply injects the drug himself every eight weeks, the way
diabetics give themselves insulin.
Only dermatologists can prescribe the drug, but Gosse said he’s
encouraging others to talk to their doctors so they can get the relief
he feels fortunate to have now.
“The suffering is now needless,” he said. “There is genuine,
practical, effective, affordable help. You can have your life back.”
He said sometimes the treatment takes a few months to kick in, but
when it does it makes it all worthwhile.
While he’s still in the trial phase of the drug, he said the province
recently indexed it for coverage.
He’s hopeful that by the time the study ends, the province will pick
up the tab so he can continue the treatment and keep his life the way
it is now.
Wants to help others
Gosse wants to let others with psoriasis know there’s hope.
He recently joined the board of the Canadian Skin Patient Alliance,
and he dispenses this advice: don’t let previous disappointments stop
you from trying new drugs, and don’t let anyone tell you that you
can’t try them. Most of all, don’t get frustrated and give up looking
for relief.
“The first time you go out with a pair of shorts on, or you go
swimming ... you will have your life back and it is an incredible
feeling,” he said.
<sniP>
I ony suggest there is a truth.
And you find yours.
randall.... whose safe at home and found his... :)
JRStern
wrote:
Limitation of vitamin D?
odd, that.
I dunno.
Several years? "Favorable responses"?
vague.
>http://www.thetelegram.com/index.cfm?sid=312230&sc=85
>Finally comfortable in his own skin
>New psoriasis treatment gives Andrew Gosse his life back
38%, hah.
And they never name the drug?
J.
Skeats
"JRStern" <JRS...@foobar.invalid> wrote in message
news:9gtqi5t9fdv8hh491...@4ax.com...
A course of UVB treatment completely clears up my skin for months so I
personally believe that I have a problem with digesting Vitamin D through
food, even with supplements. I don't have osteoporosis though so Calcium
isn't a problem.
It's funny though, I only get a few plaques on my forearms now, whereas
before I used to get hair, nails and legs affected so am wondering if
certain bugs only are involved in my case. (An article lately having
informed me that there are different bugs on the skin on various parts of
the body)!
I've been taking acidophilus in various forms, ie, non dairy powder,
tablets, yogurt etc for the past thirty years so maybe it takes donkeys
years for the system to right itself.
Happy Christmas to all on the forum. Minus 3 in Edinburgh not much snow yet
but very slippery underfoot.
Skeats
randall
> On Sat, 19 Dec 2009 11:10:28 -0800 (PST), randall <ranhu...@aol.com>
Bill Faloon in his January 2009 address to the LE Masses
will wonder why obama care doesn't mandate D3 supplementation
I would suppose:
http://www.lef.org/magazine/mag2009/jan2009_Millions-of-Needless-Deaths_01.htm
>
> odd, that.
>
> I dunno.
>
> Several years? "Favorable responses"?
Right.
Where are the follow up benicar (cures psoriasis) studies?
Or did they show something else entirely unexpected?
And get quashed?
Benicar psor cure quashed by big pharma?
Nah, not even possible with free speech? <G>
>
> vague.
>
> >http://www.thetelegram.com/index.cfm?sid=312230&sc=85
> >Finally comfortable in his own skin
> >New psoriasis treatment gives Andrew Gosse his life back
>
> 38%, hah.
>
> And they never name the drug?
>
> J.
J
He's in the UK. So once they get THEIR generic mAB's
who knows what they name it?
QueenmAB of the NHS?
http://www.biology.iupui.edu/biocourses/Biol540/6secondwavefullCSS.html
Yet isn't it rather unsocialized of their UK NHS system?
http://en.wikipedia.org/wiki/National_Health_Service
Or is that our system? Or system to BE? LOL
http://en.wikipedia.org/wiki/Socialized_medicine
None the less the UK has had FAE's for years while we've had mAB's for
years:
http://www.webmd.com/skin-problems-and-treatments/news/20031119/new-psoriasis-treatments-work
And a queen mab seems to have been overlooked for LONG now? LOL
Not the poem the drug:
http://www.bartleby.com/139/shel111.html
My position still doesn't change HOW CHEAP the mAB may BE.
Or good the poem:
HOW wonderful is Death,
Death, and his brother Sleep!
One, pale as yonder waning moon
With lips of lurid blue;
The other, rosy as the morn
When throned on ocean's wave
It blushes o'er the world;
Yet both so passing wonderful!
<sniP>
Why treat anything BUT causation?
http://en.wikipedia.org/wiki/Causality
Did daveW use to say something like this?
http://en.wikipedia.org/wiki/Correlation_does_not_imply_causation
"Correlation does not imply causation" is a phrase used in science and
statistics to emphasize that correlation between two variables does
not automatically imply that one causes the other (though it does not
remove the fact that correlation can still be a hint, whether powerful
or otherwise[1][2]). The opposite phrase, correlation proves
causation, is a logical fallacy by which two events that occur
together are claimed to have a cause-and-effect relationship. The
fallacy is also known as cum hoc ergo propter hoc (Latin for "with
this, therefore because of this") and false cause. By contrast, the
fallacy post hoc ergo propter hoc requires that one event occur before
the other and so may be considered a type of cum hoc.
<sniP>
Back on my high hobby horse now.
http://home.iprimus.com.au/phildoyle/chillingham/HobbyHorse.JPG
Furthermore all socialism is uncivilized and only a ruse to TAX
the rubes. LOL
http://en.wikipedia.org/wiki/Deception
Hey! RUBE
http://en.wikipedia.org/wiki/Hey,_Rube!
But i'm positive Skeats is getting her money's worth. <W>
Which makes sense as she keeps the world from imploding.
randall... well someone has to do it.
randall
> "JRStern" <JRSt...@foobar.invalid> wrote in message
>
> news:9gtqi5t9fdv8hh491...@4ax.com...
>
>
>
>
>
> > On Sat, 19 Dec 2009 11:10:28 -0800 (PST), randall <ranhu...@aol.com>
>
> - Show quoted text -
Skeats,
Merry Christmas to you. :)
But minus 3 C is 30 degrees F, which is within keeping
with the SEASON's.
OToH we've got unSEASONAL 70 degress F today as
the San Diego Chargers lead the Cincinnati bengals 7 to 3.
Whoops... fifty yard plus pass and touchdown cinci.... :(
randall... it is all a matter of perspective? LOL
Skeats
"randall" <ranh...@aol.com> wrote in message
news:e5f3427b-36af-4a93...@a10g2000pre.googlegroups.com...
Skeats,
That's me! That's me!!
Maybe I have been reversing these "whatyoucallits" gradually over all these
years that my P has reduced so much.
I wonder when they will try it in the uk.
Glad I'm not where you are at the moment. I've been in minus 30 when
visiting Moscow one February years ago and wouldn't want to repeat it.
Skeats
jay
May be a NQO1 (ph II enzyme) variant?
> Which brings up CYP450 ...
> Yet severe psoriatics most likely add to their skewy Th1 situation
> by not taking a gram or so every other day of NAC.
> Same with the far skewed cancerous Th2 ...
> And in which case you can skiP the brassica. My favorite being
> the mustard. Yet i've enjoyed recentlly the effects of capers
> (quercetin) and apigenin or luteolin rich veggies. Celery being high
> on that list (http://en.wikipedia.org/wiki/Quercetin)
Parsely, high in apigenin, tend to give me racoon eyes.
> Yet with anti ROS oral or ___topical___ supplementation your still
> only playing with a fraction of the equation...
> While present day scientists are unwittingly and slowly proving my
> garden of eden (not eating --as proper dietary regimens will create
> good gut flora and immune homeostasis) theory, they still can't see
> the forest from the tree's let alone
> the beneficial and health restorative effects of lacti loving gut
> bacteria.
> [Unless my current L. Plantarum study/trial does prove without a doubt
> some day that
> the Th17--> TH22 subsets are caused by excessive SFB, segmented
> filamentous bacterium
> in the ileum due to a alkaline colon instead of a slightly acidic one
> full of lacti loving gut flora).
I wish I could still enjoy yogurt.
> Reversing bacteria-induced vitamin D receptor dysfunction is key to
> autoimmune disease.
Maybe your lactobacteria already produce an antibiotic against such
bacteria?
> Topical calcitriol does suppress immunity without the rays ...
> Vitamin d endocrine system and psoriasis vulgaris - review of the
> literature.
Who knew sunlight and vitamin D have so many consequences? I guess I
better get a little more sun.
randall
Jay,
I don't know what to say in regards to vitiligo and Ai.
But i'm glad your working on it from outside in or inside
out.
Surely we will discover new ways to affect the Ai gwas?
randall...