The critically-acclaimed new book "AIDS: An Explosion of the Biological Time-bomb?" (Robert E. Lee, c2000) is now available at Amazon.com, Borders.com, and Barnes & Noble (bn.com) Borders.com link: http://search.borders.com/fcgi-bin/db2www/search/search.d2w/Details?&mediaType=Book&prodID=51991107 Amazon.com link: http://www.amazon.com/exec/obidos/ASIN/1929882033/o/qid=970850234/sr=8-1/ref=aps_sr_b_1_3/102-3980844-3344100 Book-related website: http://www.bhc.edu/eastcampus/leeb/aids/index.html According to Dr. Alan R. Cantwell, noted AIDS researcher and author of 30 scientific articles in refereed scientific journals and 4 books on AIDS and cancer, "This is a must have book for the serious investigator of the origin of AIDS." An extended chapter outline follows: Prologue/Introduction: A broad history of biological warfare and leukemia research over the last 60 years as well as a brief history documenting the appearance of HIV-1 on the world-scene. The introduction makes the case for why the present investigation is warranted. Chapter 1: Historic interest in latent and persistent infections 1930-1945; 1946-1950; a general overview of the period. Early research on T-cell attacking agents. Latent and/or persistent agents as biological weapons. US bioweaponry as "powerful as atomic weapons." Chapter 2: Activities during the early 1950s; research with birds, mice, rats. Discussion of research on human polio; cancer 1951-1955. Simian foamy viruses; sheep viruses. Chapter 3: Activities during the late 1950s; research on birds, mice, rats, hamsters. 1956-1960 cat viruses enter the paradigm. 1956-1960 sheep virus research. 1956-1960 cow viruses enter the paradigm. 1956-1960 primate virus research. 1956-1960 human viruses, e.g., adenoviruses, ECHO viruses, polio research; agents attacking the nervous system. Chapter 4: Activities during 1961-1963; research on birds (Rous sarcoma); mice, rats, e.g., Rauscher leukemia virus; immunodeficiency-causing viruses in rodents. Cat viruses causing immunodeficiency, e.g., Bolin's virus. Sheep-infecting viruses, e.g., maedi and visna viruses. Cow-infecting viruses, e.g., reovirus. Primate foamy virus research; T-cell attacking agents. Human viruses, e.g., Burkitt's lymphoma; B-cell attacking agents; reovirus, adenovirus, cellular antibody/antigen research. SV40 and other foamy primate virus contamination of polio vaccinations. Chapter 5: Activities 1964-1965; research on birds, mice, rats; T-cell attacking agents. Metabolic enzymes and leukemia; Moloney leukemia virus; Harvey leukemia virus. Co-infections with various viruses and hybrids. Infecting human cells with bird sarcoma virus. Cat-virus research; Feline leukemia virus. Sheep-virus research; maedi and visna viruses. Cow-virus research; bovine lymphosarcoma. The primate sub-paradigm; SV-40 virus. 1964-1965 study of human nervous-system attacking slow-latent viruses, e.g., Kuru, multiple sclerosis, amyltropic lateral sclerosis; Burkitt's lymphoma; adenoviruses. Virus and cellular hybrids. Chapter 6: Activities 1966-1967. Bird, mouse, rat viruses. Infecting human cells with sarcoma-causing bird viruses. More immunodeficiency-causing mouse viruses, e.g., suckling-mouse virus; Friend virus, Gross virus; Rauscher virus; Moloney virus; Kirsten virus. Infecting various species with different viruses. Cat-virus research; Feline leukemia virus. Sheep-virus research; transmission of maedi-visna virus. Cow viruses; infecting other species. Primate viruses, e.g., SV40; appearance of Marburg virus in humans transmitted from primates. Human leukemia and lymphoma research, e.g., Burkitt's lymphoma; immunological activity of Burkitt's lymphoma virus; cancer research; infecting human cells with cow viruses; T-cell attacking leukemias; metabolic activities of leukemias. Chapter 7: Activities 1968-1969. Bird, mouse, rat viruses. Herpes infections; Moloney leukemia-sarcoma virus; Friend, Rauscher viruses; Kirsten leukemia-sarcoma virus; more immunodeficiency-causing viruses, e.g., New Zealand mouse disease. Studies of T-cell attacking agents, e.g., LCM. Mouse-mammary tumor virus. Cat immunodeficiency virus; T-cell attacking agents. Infecting cow and pig cells with the sheep-infecting Maedi-visna virus; study of cows infected with bovine lymphosarcoma. Enhancing virus effects with SV40 in primates; lactic dehydrogenase deregulation via virus infection. Development of mouse-human cellular hybrids; Burkitt's lymphoma. Chapter 8: Activities 1970-1971. Bird, mouse, rat viruses. Oncogenes. Discovery of reverse-transcriptase, retroviruses; RNA-DNA. Moloney virus, Abelson virus; Harvey virus; Friend virus; Mouse mammary-tumor virus. Cat viruses, e.g., fibrosarcoma, rhabdomyosarcoma, RD-114. Sheep and goat viruses, progressive pneumonia virus. Cow viruses; e.g., bovine leukemia virus, lymphosarcoma virus; bovine syncytial virus. Primate viruses, e.g., Mason-Pfizer monkey virus; SV40; simian sarcoma virus. Transforming human cells with mouse and bird cancer-causing viruses; infecting human cells with mouse leukemia/lyphoma-causing viruses. Cross-species infections using leukemia/lyphoma agents. 1970 Department of Defense appropriation for biological warfare agents that cause immunodeficiency. Chapter 9: Activities 1972-1973. Bird, mouse, rat viruses. Cat viruses. Infecting baboon cells with cat viruses. Sheep viruses. Cow virus research. Primate virus research; isolating new immunodeficiency-causing agents. Transforming vs non-transforming lymphoma viruses. Gibbon leukemia/lymphoma virus. Human leumia viruses; reverse transcriptase in human cells. Developing a "family tree" of immuodeficiency-causing retroviruses. 1972 World Health Organization's call for research on viruses that can selectively target T-cells of the immune system. Chapter 10: Activities during 1974-1975. Bird, mouse, rat viruses. Kirsten, Rauscher, Abelson viruses. Discovery of other immunologically-impairing viruses. Cat virus research; arguments for "evolutionary development" of immunologically-disruptive viruses. Sheep viruses. Cow viruses; bovine-visna virus. Primate viruses; gibbon ape leukemia virus. Human viruses; SV40 virus causing cancer in humans; Kirsten leukemia signatures in human leukemias; developing an "evolutionary tree" of leukemias -- an effort to disguise past research? Chapter 11: Activities 1976-1977. Bird, mouse, rat viruses. Understanding the mechanisms of cellular attacks by leukemias. Structure and function of leukemia viruses. Sheep viruses; discussion of human cells infected by visna virus. Cow viruses; moving diseases across species lines. Primate viruses; SV40. Human viruses; SV40. Appearance of "Gay Bowel Syndrome" in California. Kaposi's sarcoma outbreak in Africa. Recognition of structure and functions of various immunodeficiency-causing viruses. Chapter 12: Activities 1978-1980. Birds, mouse, rat viruses. Sarcomas; temperature-sensitive mutant sarcomas; transforming vs non-transforming sarcoma viruses. Feline sarcoma virus. Sheep viruses. Cow viruses. Infection of human cells with visna virus. Primate viruses; gibbon ape leukemia/sarcoma. Human leukemias; HTLV-1; HTLV-II; T-cell research. Appearance of HTLV-III (now called HIV-1, or AIDS) in humans. Chapter 13: Activities 1981-1982. Bird, mouse, rat viruses. Genetics, switches, oncogenes. How T-cell attacking agents bind to T-cells. Harvey sarcoma virus; Moloney sarcoma virus. Sheep viruses; antigenic variations of visna. Simian sarcoma virus. Substantial study of T-cell attacking viruses in humans. Burkitt's lymphoma; Kaposi's sarcoma; associations of leukemias and neurologically-attacking agents. Chapter 14: Activities 1983-1985. Bird, mouse, rat viruses. Structures and functions of oncogenes. Transforming growth factors. Herpes and leukemias/lymphomas. Sheep viruses; trojan-horse mechanisms of attack. Cow viruses; T-cells; human leukemias. Primate viruses; SV40; oncogene of simian sarcoma virus; Simian AIDS; Wooley monkey sarcoma; gibbon ape leukemia. Human leukemias; HTLV-I; HTLV-II; AIDS (formerly known as HTLV-III); HTLV-I and -II as a T-cell attacking agent. Tyrosine phosphorylation, effects of disease; ethnicity. Chapter 15: Activities 1986-1988. Bird, mouse, rat viruses. T-cell attacking leukemias; sarcomas. Growth factors; influence on disease. Metabolic enzymes; disturbances by disease. Cat viruses; baboon-cat viruses. Cow-viruses; herpes/leukosis viruses; infection of offspring from milk of infected adult. Primate leukemia viruses; SIV-I; the African green monkey. Humans and AIDS; AIDS dementia; how HIV-1 infects cells; HIV-1's comparison to other immunodeficiency causing agents; epidermal growth factor; tyrosine kinase; Philadelphia chromosome; ethnicity and AIDS; Peter Duesburg. Chapter 16: Epilogue. A recapitulation of important historical notes; important statements from Amos, et. al (1972); US Army document suggesting ethnic-group-specific biological warfare (1975); A restatement of the question: "Where did AIDS come from?" and a likely answer.