Yes, to some things. But the relevant question is not whether this
desensitization makes it impossible for the experience of a premiere
to be recreated, but rather why it would be desirable to do so in the
first place.
The idea that an experience of any kind can be "recreated" is
dubious. You and I may sit in adjacent seats at the same performance
and have entirely different experiences of it. To some extent we may
say that the generalized experience of an audience at a premier may
have some effect on the perception of a work and its impact, but
surely this becomes less and less important over time--ie, we may be
interested to know that the audience at the Eroica premier found it
interminable and incomprehensible, but this has little to do with our
sense of the piece's place in music history, which is much more likely
to be defined by its influence on generations of composers and the
enthusiasm of generations of audience members.