Neuronal correlates of symptom formation in functional somatic syndromes
From the abstract:
Fifteen subjectively electrosensitive patients and 15 age- and
gender-matched healthy controls were exposed to sham mobile phone
radiation and heat as a control condition. The perceived stimulus
intensities were rated on a five-point scale. During anticipation of
and exposure to sham mobile phone radiation increased activations in
anterior cingulate and insular cortex as well as fusiform gyrus were
seen in the electrosensitive group compared to controls, while heat
stimulation led to similar activations in both groups. Symptom
manifestation during sham exposure to mobile phone radiation was
accompanied by specific alterations of cortical activity in anterior
cingulate and insular cortex in subjectively electrosensitive
patients further supporting the involvement of these areas in the
perception of unpleasantness and generation of functional somatic
syndromes.
Bibliography: Landgrebe et al., Neuroimage. 2008 Jul 15;41(4):1336-44, Abstract
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