No, it cannot.
Use of expressions (including use of parameters defined in .PARAM statements) is only legal in certain contexts, and .TRAN is not one of them.
There is an open enhancement request to change this, but at the moment the only places where expressions are legal are in device instance lines, model cards, .param and .global_param lines, and on .print lines. For what it's worth, this is mentioned in the "Known defects and workarounds" section of the release notes, as it is a common request that expressions be usable everywhere any number can be used, but one we have not risen in priority above our other requirements.