Hi Denis,
welcome to XtreemFS then!
I am not sure if anyone can provide you with a comparison here, and I am not very familiar with MogileFS, but in general I'd say that you can expect XtreemFS to be reliable and unlikely to surprise you with things like "not handling large files well". However, XtreemFS probably doesn't have an as-long track record in production as MogileFS has, so you might find things missing in the production monitoring and tools side of things. In this case, please let us know, or feel free to add things yourself.
* XtreemFS also has "automatic" file replication, which I'd say is pretty flexible and configurable.
* We currently have single point of failure, our metadata and directory server, but implementing replication for them is underway
* XtreemFS is a full-featured distributed file system, POSIX compliant, incl. ACLs, etc.
* XtreemFS has checksums
... Felix