Hi!
The edge triggers will generate note-on and note-off event on a transition from one state to another (ex. low to high/ high to low).
So ... switch moves from "off" to "on" and WVR starts a sample from the beginning, that same switch moves from "on" to "off" and WVR stops the sample.
At boot it will not begin playing sounds, it must receive a transition.
You can write some Arduino code to overcome this, if you want it to start at boot.
It could read all the pins, and start some loops accordingly.
There are no built-in functions to handle potentiometers or encoders, these would require a little Arduino code.
Global pitch and global volume could definitely be accomplished.
So I think the answer to all your questions is yes, but, with some Arduino code. Happy to support you in this task if you are not comfortable in Arduino.