Damn I could have used that about 4 years ago. I worked on a project with a guy doing Medical Imaging and we were doing everything using GDI+. I think we got scaling for free by using a Transform group (like in this example). We added annotations to it after the transform so that they were always legible. I also remember reading about using Annotations to do this but I couldn’t get the anchors to stick to a specific location in a picture.