Nanoparticles target anti-inflammatory drugs where neededResearchers at the University of Illinois at Chicago have developed a system for precisely delivering anti-inflammatory drugs to immune cells gone out of control, while sparing their well-behaved counterparts. Their findings were published online Feb. 23 in Nature Nanotechnology. The system uses nanoparticles made of tiny bits of protein designed to bind to unique receptors found only on neutrophils, a type of immune cell engaged in detrimental acute and chronic inflammatory responses.
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http://www.worldpharmanews.com/research/2711-nanoparticles-target-anti-inflammatory-drugs-where-needed
Eliquis® (apixaban) reduced the risk of stroke and demonstrated fewer major bleeding events versus WarfarinBristol-Myers Squibb Company (NYSE: BMY) and Pfizer Inc. (NYSE: PFE) have announced results of a pre-specified subanalysis of the Phase 3 ARISTOTLE trial in relation to patient age. ARISTOTLE was designed to evaluate the efficacy and safety of Eliquis compared to warfarin for reducing the risk of stroke or systemic embolism in patients with nonvalvular atrial fibrillation (NVAF).
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http://www.worldpharmanews.com/pfizer/2710-eliquisr-apixaban-reduced-the-risk-of-stroke-and-demonstrated-fewer-major-bleeding-events-versus-warfarin
Scientists find resistance mechanism that could impact antibiotic drug developmentThe use of antibiotics is often considered among the most important advances in the treatment of human disease. Unfortunately, though, bacteria are finding ways to make a comeback. According to the Centers for Disease Control, more than two million people come down with antibiotic-resistant infections annually, and at least 23,000 die because their treatment can't stop the infection.
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http://www.worldpharmanews.com/research/2709-scientists-find-resistance-mechanism-that-could-impact-antibiotic-drug-development
Bevacizumab (Avastin) fails to improve survival for newly diagnosed glioblastoma patientsAdding bevacizumab (Avastin) to standard chemotherapy and radiation treatment does not improve survival for patients newly diagnosed with the often deadly brain cancer glioblastoma, researchers report in the Feb. 20 issue of the New England Journal of Medicine.
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http://www.worldpharmanews.com/research/2708-bevacizumab-avastin-fails-to-improve-survival-for-newly-diagnosed-glioblastoma-patients
Boehringer Ingelheim receives East Bay Innovation AwardBoehringer Ingelheim Fremont Inc. received the East Bay Innovation Award in recognition for its contribution to the East Bay's culture of innovation. Boehringer Ingelheim's Fremont, California site is an arm of its biopharmaceutical division and provides the entire production technology chain from DNA to drug substance.
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http://www.worldpharmanews.com/boehringer-ingelheim/2707-boehringer-ingelheim-receives-east-bay-innovation-award
New drug candidate starves dormant cancer cellsIn a study published in Nature Communications, researchers at Karolinska Institutet and Uppsala University in Sweden present a new drug candidate, which selectively kills dormant cells within a cancer tumour through starvation. These tumour cells, which are found in less oxygenated parts of solid tumours, are resistant to conventional treatments.
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http://www.worldpharmanews.com/research/2706-new-drug-candidate-starves-dormant-cancer-cells
Clinical trial success influenced by biomarker- and receptor-targeted therapies in NSCLCOver the past decade, a great clinical focus has been directed at developing new and innovative therapies for advanced non-small cell lung cancer (NSCLC). An analysis of clinical trials evaluating these therapies demonstrates that the cumulative success rate for new agents for advanced NSCLC is lower than the industry-estimated rate. However, biomarker- and receptor-targeted therapies were found to substantially increase clinical trial success.
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http://www.worldpharmanews.com/research/2705-clinical-trial-success-influenced-by-biomarker-and-receptor-targeted-therapies-in-nsclc
Novartis expands cancer immunotherapy research program with acquisition of CoStimNovartis announced today that it is broadening its cancer immunotherapy research program with the acquisition of CoStim Pharmaceuticals Inc., a Cambridge, MA-based, privately held biotechnology company focused on harnessing the immune system to eliminate immune-blocking signals from cancer.
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http://www.worldpharmanews.com/novartis/2704-novartis-expands-cancer-immunotherapy-research-program-with-acquisition-of-costim
PharmaNews.eu / Latest NewsScientists unlock a 'microbial Pompeii'
http://www.pharmanews.eu/research-and-development/1407-scientists-unlock-a-microbial-pompeii
eHealth Forum 2014
http://www.pharmanews.eu/conferences-and-events/1406-ehealth-forum-2014Kidney cancer reveals its weak link
http://www.pharmanews.eu/research-and-development/1405-kidney-cancer-reveals-its-weak-linkNew blood cells fight brain inflammation
http://www.pharmanews.eu/research-and-development/1404-new-blood-cells-fight-brain-inflammationTwo new weapons in the battle against bacteria
http://www.pharmanews.eu/research-and-development/1403-two-new-weapons-in-the-battle-against-bacteria
"Green light" for Bayer's new transparent low dose contraceptive patch
http://www.pharmanews.eu/bayer/1402-qgreen-lightq-for-bayers-new-transparent-low-dose-contraceptive-patch
mHealth Summit Europe 2014 Call for Papers
http://www.pharmanews.eu/conferences-and-events/1401-mhealth-summit-europe-2014-call-for-papers
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