GSK joins with research councils in UK and South Africa to tackle non-communicable diseasesGSK has announced a £5m collaboration with the UK and South African Medical Research Councils, to support much-needed research into non-communicable diseases (NCDs) in Africa, as part of GSK's Africa NCD Open Lab initiative.
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http://www.worldpharmanews.com/gsk/2884-gsk-joins-with-research-councils-in-uk-and-south-africa-to-tackle-non-communicable-diseasesDiscovery paves the way for a new generation of chemotherapiesA new mechanism to inhibit proteasomes, protein complexes that are a target for cancer therapy, is the topic of an article published in the journal Chemistry & Biology. The first author of the study is Daniela Trivella, researcher at the Brazilian Biosciences National Laboratory at the Brazilian Center for Research in Energy and Materials (LNBio/CNPEM).
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http://www.worldpharmanews.com/research/2883-discovery-paves-the-way-for-a-new-generation-of-chemotherapiesResearchers improve severe asthma care through new, antibody-based treatmentA team of researchers at McMaster University and St. Joseph's Healthcare Hamilton have successfully evaluated a new, antibody-based drug for certain patients with severe asthma. The drug - named mepolizumab - can replace traditional, steroid-based treatments for a specific subset of patients, resulting in improved outcomes and reduced side effects.
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http://www.worldpharmanews.com/research/2882-researchers-improve-severe-asthma-care-through-new-antibody-based-treatmentSafety and sustained benefits of Adempas® from Bayer confirmed by results of long-term studiesData presented at the European Respiratory Society (ERS) Congress today confirm the safety profile and the sustained efficacy of Adempas® (riociguat) over at least two years of treatment in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH) or persistent or recurrent CTEPH after surgical treatment, and in patients with pulmonary arterial hypertension (PAH).
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http://www.worldpharmanews.com/bayer/2881-safety-and-sustained-benefits-of-adempasr-from-bayer-confirmed-by-results-of-long-term-studiesOxidized LDL might actually be 'good guy'A team of investigators at the University of Kentucky has made a thought-provoking discovery about a type of cholesterol previously believed to be a "bad guy" in the development of heart disease and other conditions. Jason Meyer, a University of Kentucky MD-PhD candidate, worked with Deneys van der Westhuyzen, Ph.D., a Professor in the Departments of Internal Medicine and Molecular and Cellular Biochemistry, to study the role oxidized LDL plays in the development of plaque inside artery walls.
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http://www.worldpharmanews.com/research/2880-oxidized-ldl-might-actually-be-good-guyScientists discover how to 'switch off' autoimmune diseasesScientists have made an important breakthrough in the fight against debilitating autoimmune diseases such as multiple sclerosis by revealing how to stop cells attacking healthy body tissue. Rather than the body's immune system destroying its own tissue by mistake, researchers at the University of Bristol have discovered how cells convert from being aggressive to actually protecting against disease.
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http://www.worldpharmanews.com/research/2879-scientists-discover-how-to-switch-off-autoimmune-diseasesAstraZeneca and Redx Pharma agree research collaborationAstraZeneca today announced that it has entered into a research collaboration with Redx Pharma Limited to discover and develop new molecules targeting a genetic driver of tumour growth and survival. The research will complement AstraZeneca's strategic approach focused on genetic drivers of cancer and mechanisms of resistance to established and novel cancer therapies.
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http://www.worldpharmanews.com/astrazeneca/2878-astrazeneca-and-redx-pharma-agree-research-collaborationNovartis' new heart failure medicine LCZ696 cut cardiovascular deaths by 20% vs. ACE-inhibitor in landmark PARADIGM-HF trialAt the European Society of Cardiology congress and published simultaneously in the New England Journal of Medicine, Novartis revealed that its investigational heart failure medicine, LCZ696, was superior to ACE-inhibitor enalapril on key endpoints in the largest heart failure study ever done[1],[6].
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http://www.worldpharmanews.com/novartis/2877-novartis-new-heart-failure-medicine-lcz696-cut-cardiovascular-deaths-by-20-vs-ace-inhibitor-in-landmark-paradigm-hf-trialNew data indicates Brilinta/Brilique™ has the flexibility to be initiated pre-hospital or in hospital in STEMI patientsAstraZeneca has announced the results of the Phase IV ATLANTIC study, which indicates that the profile of BRILINTA/BRILIQUE™ (ticagrelor) is comparable whether administered in a pre-hospital or in-hospital setting to ST segment elevation myocardial infarction (STEMI) patients.
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http://www.worldpharmanews.com/astrazeneca/2876-new-data-indicates-brilintabrilique-has-the-flexibility-to-be-initiated-pre-hospital-or-in-hospital-in-stemi-patientsWine only protects against CVD in people who exerciseWine only protects against cardiovascular disease (CVD) in people who exercise, according to results from the In Vino Veritas (IVV) study presented at ESC Congress by Professor Milos Taborsky from the Czech Republic. Professor Taborsky said: "This is the first randomised trial comparing the effects of red and white wine on markers of atherosclerosis (1) in people at mild to moderate risk of CVD.
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http://www.worldpharmanews.com/research/2875-wine-only-protects-against-cvd-in-people-who-exerciseA new synthetic amino acid for an emerging class of drugsOne of the greatest challenges in modern medicine is developing drugs that are highly effective against a target, but with minimal toxicity and side-effects to the patient. Such properties are directly related to the 3D structure of the drug molecule. Ideally, the drug should have a shape that is perfectly complementary to a disease-causing target, so that it binds it with high specificity.
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http://www.worldpharmanews.com/research/2874-a-new-synthetic-amino-acid-for-an-emerging-class-of-drugsEbola vaccine trials fast-tracked by international consortiumA candidate Ebola vaccine could be given to healthy volunteers in the UK, The Gambia and Mali as early as September, as part of a series of safety trials of potential vaccines aimed at preventing the disease that has killed more than 1,400 people in the current outbreak in west Africa.
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http://www.worldpharmanews.com/gsk/2873-ebola-vaccine-trials-fast-tracked-by-international-consortiumNIH to launch human safety study of Ebola vaccine candidateInitial human testing of an investigational vaccine to prevent Ebola virus disease will begin next week by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The early-stage trial will begin initial human testing of a vaccine co-developed by NIAID and GlaxoSmithKline (GSK) and will evaluate the experimental vaccine's safety and ability to generate an immune system response in healthy adults.
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http://www.worldpharmanews.com/development/2872-nih-to-launch-human-safety-study-of-ebola-vaccine-candidatePharmaNews.eu / Latest NewsEating is addictive but sugar and fat are not like drugs, study says
http://www.pharmanews.eu/research-and-development/1474-eating-is-addictive-but-sugar-and-fat-are-not-like-drugs-study-saysScientists discover how to 'switch off' autoimmune diseases
http://www.pharmanews.eu/research-and-development/1473-scientists-discover-how-to-switch-off-autoimmune-diseasesWine only protects against CVD in people who exercise
http://www.pharmanews.eu/research-and-development/1472-wine-only-protects-against-cvd-in-people-who-exerciseFighting prostate cancer with a tomato-rich diet
http://www.pharmanews.eu/research-and-development/1471-fighting-prostate-cancer-with-a-tomato-rich-dietA novel pathway for prevention of heart attack and stroke
http://www.pharmanews.eu/research-and-development/1470-a-novel-pathway-for-prevention-of-heart-attack-and-strokeUCB expands access to clinical study data
http://www.pharmanews.eu/ucb/1469-ucb-expands-access-to-clinical-study-dataEurope to boost cooperation with international partners on generics
http://www.pharmanews.eu/ema/1468-europe-to-boost-cooperation-with-international-partners-on-genericsWith best regards,
Ruslan David
Administrator/Editor
DAVID eHealth & Pharma UG,
Saarland University, Starterzentrum, Building A1 1,
66123, Germany
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