World Pharma News Digest - 20.01.2014
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Ruslan David
Jan 20, 2014, 5:53:09 AM1/20/14
to worldph...@googlegroups.com
Clever chemistry and a new class of antibiotics
As concerns about bacterial resistance to antibiotics grow, researchers are racing to find new kinds of drugs to replace ones that are no longer effective. One promising new class of molecules called acyldepsipeptides - ADEPs - kills bacteria in a way that no marketed antibacterial drug does - by altering the pathway through which cells rid themselves of harmful proteins.
Read more...
http://www.worldpharmanews.com/research/2675-clever-chemistry-and-a-new-class-of-antibiotics
Scientists demonstrate method to find new therapies
Scientists at The Scripps Research Institute (TSRI) have demonstrated the power of a new drug discovery technique, which allows them to find - relatively quickly and cheaply - antibodies that have a desired effect on cells. The TSRI scientists used the technique to discover two antibodies that protect human cells from a cold virus.
Read more...
http://www.worldpharmanews.com/research/2674-scientists-demonstrate-method-to-find-new-therapies
AstraZeneca and Bristol-Myers Squibb Diabetes Alliance provides $5 million grant for American Diabetes Association's Pathway to Stop Diabetes
AstraZeneca (NYSE:AZN) and Bristol-Myers Squibb Company (NYSE:BMY) today announced that the companies' U.S. Diabetes Alliance is providing a three-year grant to the American Diabetes Association's Pathway to Stop Diabetes program. The innovative research initiative provides resources and support for a new generation of diabetes researchers and is designed to generate exciting discoveries through excellence, innovation, collaboration and radical thinking.
Read more...
http://www.worldpharmanews.com/bms/2673-astrazeneca-and-bristol-myers-squibb-diabetes-alliance-provides-5-million-grant-for-american-diabetes-associations-pathway-to-stop-diabetes
World's tiniest drug cabinets could be attached to cancerous cells for long term treatment
Reservoirs of pharmaceuticals could be manufactured to bind specifically to infected tissue such as cancer cells for slow, concentrated delivery of drug treatments, according to new research published in ACS Macro Letters. The findings, from the University of Copenhagen and the Institut Laue-Langevin (ILL), came as a result of neutron reflectometry studies at the world's leading neutron source in Grenoble, France.
Read more...
http://www.worldpharmanews.com/research/2672-worlds-tiniest-drug-cabinets-could-be-attached-to-cancerous-cells-for-long-term-treatment
Tafinlar® receives FDA Breakthrough Therapy designation for non-small cell lung cancer with BRAF mutation
GlaxoSmithKline plc (LSE: GSK) announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation for Tafinlar® (dabrafenib) for treatment of patients with metastatic BRAF V600E mutation-positive non-small cell lung cancer (NSCLC) who have received at least one prior line of platinum-containing chemotherapy.
Read more...
http://www.worldpharmanews.com/gsk/2671--tafinlarr-receives-fda-breakthrough-therapy-designation-for-non-small-cell-lung-cancer-with-braf-mutation
Scientists develop promising drug candidates for pain, addiction
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have described a pair of drug candidates that advance the search for new treatments for pain, addiction and other disorders. The two new drug scaffolds, described in a recent edition of The Journal of Biological Chemistry, offer researchers novel tools that act on a demonstrated therapeutic target, the kappa opioid receptor (KOR), which is located on nerve cells and plays a role in the release of the neurotransmitter dopamine.
Read more...
http://www.worldpharmanews.com/research/2670-scientists-develop-promising-drug-candidates-for-pain-addiction
Study questions anti-cancer mechanisms of drug tested in clinical trials
The diabetes drug metformin is also being tested in numerous clinical trials for treating different cancers, and several studies point to its apparent activation of a molecular regulator of cell metabolism called AMPK to suppress tumor growth. But new research appearing the week of Jan. 13 in Proceedings of the National Academy of Sciences (PNAS) suggests that activation of AMPK may actually fuel cancer growth.
Read more...
http://www.worldpharmanews.com/research/2669-study-questions-anti-cancer-mechanisms-of-drug-tested-in-clinical-trials
PharmaNews.eu / Latest News
Top Portuguese and Finnish scientists to lead IMI Scientific Committee
http://www.pharmanews.eu/research-and-development/1388-top-portuguese-and-finnish-scientists-to-lead-imi-scientific-committee
PRAC recommends suspending use of Protelos/Osseor
http://www.pharmanews.eu/ema/1387-prac-recommends-suspending-use-of-protelososseor
Research uncovers key difference between our bodies' fight against viruses and bacteria
http://www.pharmanews.eu/research-and-development/1386-research-uncovers-key-difference-between-our-bodies-fight-against-viruses-and-bacteria
New clues to how bacteria evade antibiotics
http://www.pharmanews.eu/research-and-development/1384-new-clues-to-how-bacteria-evade-antibiotics
Cancer drug protects against diabetes
http://www.pharmanews.eu/research-and-development/1383-cancer-drug-protects-against-diabetes
Marine bacteria to fight tough infections
http://www.pharmanews.eu/research-and-development/1385-marine-bacteria-to-fight-tough-infections
Genetic variants linked with schizophrenia have impact in healthy carriers
http://www.pharmanews.eu/research-and-development/1382-genetic-variants-linked-with-schizophrenia-have-impact-in-healthy-carriers
With best regards,
Ruslan David
Administrator/Editor
DAVID eHealth & Pharma UG,
Saarland University, Starterzentrum, Building A1 1,
66123, Germany
eHealthNews.eu, http://www.ehealthnews.eu
eHealthServer.com, http://www.ehealthserver.com
eHealthServer.de, http://www.ehealthserver.de
World Pharma News, http://www.worldpharmanews.com
PharmaNews.eu, http://www.pharmanews.eu
PS: Be on top of World Pharma News. Advertise with us!
World Pharma News is the leader in coverage and distribution of the top pharma industry, research and conference news. World Pharma News is one of the most visited sites on the Internet for pharma decision-makers looking for the latest breaking news. Why not put this traffic to work for you? It costs only a fraction of other on-line publications with far fewer readers. For further information, please download World Pharma News' Media Pack: http://www.worldpharmanews.com/contact-us
As concerns about bacterial resistance to antibiotics grow, researchers are racing to find new kinds of drugs to replace ones that are no longer effective. One promising new class of molecules called acyldepsipeptides - ADEPs - kills bacteria in a way that no marketed antibacterial drug does - by altering the pathway through which cells rid themselves of harmful proteins.
Read more...
http://www.worldpharmanews.com/research/2675-clever-chemistry-and-a-new-class-of-antibiotics
Scientists demonstrate method to find new therapies
Scientists at The Scripps Research Institute (TSRI) have demonstrated the power of a new drug discovery technique, which allows them to find - relatively quickly and cheaply - antibodies that have a desired effect on cells. The TSRI scientists used the technique to discover two antibodies that protect human cells from a cold virus.
Read more...
http://www.worldpharmanews.com/research/2674-scientists-demonstrate-method-to-find-new-therapies
AstraZeneca and Bristol-Myers Squibb Diabetes Alliance provides $5 million grant for American Diabetes Association's Pathway to Stop Diabetes
AstraZeneca (NYSE:AZN) and Bristol-Myers Squibb Company (NYSE:BMY) today announced that the companies' U.S. Diabetes Alliance is providing a three-year grant to the American Diabetes Association's Pathway to Stop Diabetes program. The innovative research initiative provides resources and support for a new generation of diabetes researchers and is designed to generate exciting discoveries through excellence, innovation, collaboration and radical thinking.
Read more...
http://www.worldpharmanews.com/bms/2673-astrazeneca-and-bristol-myers-squibb-diabetes-alliance-provides-5-million-grant-for-american-diabetes-associations-pathway-to-stop-diabetes
World's tiniest drug cabinets could be attached to cancerous cells for long term treatment
Reservoirs of pharmaceuticals could be manufactured to bind specifically to infected tissue such as cancer cells for slow, concentrated delivery of drug treatments, according to new research published in ACS Macro Letters. The findings, from the University of Copenhagen and the Institut Laue-Langevin (ILL), came as a result of neutron reflectometry studies at the world's leading neutron source in Grenoble, France.
Read more...
http://www.worldpharmanews.com/research/2672-worlds-tiniest-drug-cabinets-could-be-attached-to-cancerous-cells-for-long-term-treatment
Tafinlar® receives FDA Breakthrough Therapy designation for non-small cell lung cancer with BRAF mutation
GlaxoSmithKline plc (LSE: GSK) announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation for Tafinlar® (dabrafenib) for treatment of patients with metastatic BRAF V600E mutation-positive non-small cell lung cancer (NSCLC) who have received at least one prior line of platinum-containing chemotherapy.
Read more...
http://www.worldpharmanews.com/gsk/2671--tafinlarr-receives-fda-breakthrough-therapy-designation-for-non-small-cell-lung-cancer-with-braf-mutation
Scientists develop promising drug candidates for pain, addiction
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have described a pair of drug candidates that advance the search for new treatments for pain, addiction and other disorders. The two new drug scaffolds, described in a recent edition of The Journal of Biological Chemistry, offer researchers novel tools that act on a demonstrated therapeutic target, the kappa opioid receptor (KOR), which is located on nerve cells and plays a role in the release of the neurotransmitter dopamine.
Read more...
http://www.worldpharmanews.com/research/2670-scientists-develop-promising-drug-candidates-for-pain-addiction
Study questions anti-cancer mechanisms of drug tested in clinical trials
The diabetes drug metformin is also being tested in numerous clinical trials for treating different cancers, and several studies point to its apparent activation of a molecular regulator of cell metabolism called AMPK to suppress tumor growth. But new research appearing the week of Jan. 13 in Proceedings of the National Academy of Sciences (PNAS) suggests that activation of AMPK may actually fuel cancer growth.
Read more...
http://www.worldpharmanews.com/research/2669-study-questions-anti-cancer-mechanisms-of-drug-tested-in-clinical-trials
PharmaNews.eu / Latest News
Top Portuguese and Finnish scientists to lead IMI Scientific Committee
http://www.pharmanews.eu/research-and-development/1388-top-portuguese-and-finnish-scientists-to-lead-imi-scientific-committee
PRAC recommends suspending use of Protelos/Osseor
http://www.pharmanews.eu/ema/1387-prac-recommends-suspending-use-of-protelososseor
Research uncovers key difference between our bodies' fight against viruses and bacteria
http://www.pharmanews.eu/research-and-development/1386-research-uncovers-key-difference-between-our-bodies-fight-against-viruses-and-bacteria
New clues to how bacteria evade antibiotics
http://www.pharmanews.eu/research-and-development/1384-new-clues-to-how-bacteria-evade-antibiotics
Cancer drug protects against diabetes
http://www.pharmanews.eu/research-and-development/1383-cancer-drug-protects-against-diabetes
Marine bacteria to fight tough infections
http://www.pharmanews.eu/research-and-development/1385-marine-bacteria-to-fight-tough-infections
Genetic variants linked with schizophrenia have impact in healthy carriers
http://www.pharmanews.eu/research-and-development/1382-genetic-variants-linked-with-schizophrenia-have-impact-in-healthy-carriers
With best regards,
Ruslan David
Administrator/Editor
DAVID eHealth & Pharma UG,
Saarland University, Starterzentrum, Building A1 1,
66123, Germany
eHealthNews.eu, http://www.ehealthnews.eu
eHealthServer.com, http://www.ehealthserver.com
eHealthServer.de, http://www.ehealthserver.de
World Pharma News, http://www.worldpharmanews.com
PharmaNews.eu, http://www.pharmanews.eu
PS: Be on top of World Pharma News. Advertise with us!
World Pharma News is the leader in coverage and distribution of the top pharma industry, research and conference news. World Pharma News is one of the most visited sites on the Internet for pharma decision-makers looking for the latest breaking news. Why not put this traffic to work for you? It costs only a fraction of other on-line publications with far fewer readers. For further information, please download World Pharma News' Media Pack: http://www.worldpharmanews.com/contact-us
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