World Pharma News Digest - 26.05.2014

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Ruslan David

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May 26, 2014, 5:16:22 AM5/26/14
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Scientists discover potential new target for cancer immunotherapy
‎Scientists have found a way to target elusive cells that suppress immune response, depleting them with peptides that spare other important cells and shrink tumors in preclinical experiments, according to a paper published online by Nature Medicine.
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http://www.worldpharmanews.com/research/2783-scientists-discover-potential-new-target-for-cancer-immunotherapy

Clinical trials designed to block autophagy in multiple cancers show promise
‎In the largest group of results to date, researchers from Penn Medicine's Abramson Cancer Center and other institutions have shown in clinical trials that the malaria drug hydroxychloroquine (HCQ) blocked autophagy in a host of aggressive cancers - glioblastoma, melanoma, lymphoma and myeloma, renal and colon cancers - and in some cases helped stabilize disease.
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http://www.worldpharmanews.com/research/2782-clinical-trials-designed-to-block-autophagy-in-multiple-cancers-show-promise

Screen of existing drugs finds compounds active against MERS coronavirus
‎Clinicians treating patients suffering from Middle East respiratory syndrome (MERS) currently have no drugs specifically targeted to the MERS coronavirus (MERS-CoV), a virus first detected in humans in 2012 that has since caused 614 laboratory-confirmed infections, including 181 that were fatal, according to the World Health Organization. The case count escalated sharply in the spring of this year, and the first cases in the United States were announced in early May.
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http://www.worldpharmanews.com/research/2781-screen-of-existing-drugs-finds-compounds-active-against-mers-coronavirus

Clarification regarding Pfizer statement
‎AstraZeneca PLC ("AstraZeneca") notes the announcement made by Pfizer Inc. ("Pfizer") dated 19 May 2014 seeking to clarify certain matters set out in its announcement on 18 May 2014 which set out its final proposal to AstraZeneca (the "Final Proposal Announcement"). Following some questions from shareholders, AstraZeneca wishes to make clear the following points:
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http://www.worldpharmanews.com/astrazeneca/2780-clarification-regarding-pfizer-statement

Study finds outcome data in clinical trials reported inadequately, inconsistently
‎There is increasing public pressure to report the results of all clinical trials to eliminate publication bias and improve public access. However, investigators using the World Health Organization's International Clinical Trials Registry Platform (ICTRP) to build a database of clinical trials involving chronic pain have encountered several challenges.
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http://www.worldpharmanews.com/research/2779-study-finds-outcome-data-in-clinical-trials-reported-inadequately-inconsistently

AstraZeneca rejects final proposal from Pfizer
‎The Board of AstraZeneca PLC notes the announcement by Pfizer Inc. of its final proposal to combine the two companies. Leif Johansson, Chairman of AstraZeneca mentioned that the final proposal is a minor improvement which continues to fall short of the Board's view of value and has been rejected.
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http://www.worldpharmanews.com/financial/2778-astrazeneca-rejects-final-proposal-from-pfizer

PharmaNews.eu / Latest News

Finnish researchers discovered a new anticancer compound using accelerated drug screening process
http://www.pharmanews.eu/research-and-development/1446-finnish-researchers-discovered-a-new-anticancer-compound-using-accelerated-drug-screening-process

Biovision presents its selection of 44 promising life sciences businesses and projects
http://www.pharmanews.eu/conferences-and-events/1445-biovision-presents-its-selection-of-44-promising-life-sciences-businesses-and-projects

AstraZeneca and MRC Laboratory of Molecular Biology to launch joint research fund
http://www.pharmanews.eu/astrazeneca/1444-astrazeneca-and-mrc-laboratory-of-molecular-biology-to-launch-joint-research-fund

Shark antibodies inspire optimization of human antibodies
http://www.pharmanews.eu/research-and-development/1442-shark-antibodies-inspire-optimization-of-human-antibodies

New agent may enhance effectiveness of radiotherapy
http://www.pharmanews.eu/research-and-development/1443-new-agent-may-enhance-effectiveness-of-radiotherapy

Atlas shows how genes affect our metabolism
http://www.pharmanews.eu/research-and-development/1440-atlas-shows-how-genes-affect-our-metabolism

CNIO team presents a new strategy to personalise cancer therapies
http://www.pharmanews.eu/research-and-development/1441-cnio-team-presents-a-new-strategy-to-personalise-cancer-therapies

With best regards,
Ruslan David
Administrator/Editor

DAVID eHealth & Pharma UG,
Saarland University, Starterzentrum, Building A1 1,
66123, Germany

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