Researchers
have linked chronic intestinal infections caused by cytomegalovirus (HCMV) to a unique subtype of Alzheimer’s disease. The virus may travel from the gut to the brain via the vagus nerve, altering immune responses and contributing to hallmark Alzheimer’s changes
like amyloid plaques and tau tangles. While HCMV infection is common and typically harmless, this study found that it may cause chronic brain inflammation in certain individuals.
Women
born in states with higher structural sexism experience faster memory decline later in life, with effects equivalent to nine years of cognitive aging. Structural sexism encompasses societal inequities like unequal labor force participation and underrepresentation
in government, which create systemic barriers to health. The impact is particularly pronounced among Black women, highlighting the intersection of sexism and racism.
A
study reveals how brain cell interactions influence aging, showing that rare cell types either accelerate or slow brain aging. Neural stem cells provide a rejuvenating effect on neighboring cells, while T cells drive aging through inflammation.
Researchers
have created a 3D atlas mapping brain regions that connect to V1 spinal interneurons, which shape motor output. By using a genetically modified rabies virus, they pinpointed connections from the brain to these diverse "switchboard operator" cells in the spinal
cord.