Gonorrhea treatment guidelines for NYC from the DOH

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Mimi Niles

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Apr 1, 2013, 1:20:02 PM4/1/13
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2012 ALERT # 6

Gonorrhea with Reduced Susceptibility to Cephalosporins Isolated from New York City Residents

1. Cefixime and other oral cephalosporins are no longer recommended for treating gonorrhea. 
2. Treat gonorrhea with a combination regimen of ceftriaxone 250 mg intramuscularly PLUS EITHER azithromycin 1 g orally as a single dose OR doxycycline 100 mg orally twice daily for 7 days. 
3. Patients treated with alternative regimens should be retested with culture and nucleic acid amplification test (NAAT) 7-10 days after treatment, as should any patients with persistent symptoms.
4. Send culture specimens to laboratories that perform antibiotic susceptibility testing and include ceftriaxone in the antibiotic panel.
5. Notify the NYC Department of Health and Mental Hygiene of suspected treatment failures. 

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