pvalue 0.000000e+00 and FDR 0.000000e+00

[May]

Dear Developers,

Could you explain what does it mean to have a pvalue 0.000000e+00 and FDR 0.000000e+00 for a biological enriched term in ORA analysis? I kept taking these values for the same biological term at the top of my different network analysis (hsa03010: Ribosome, FDR<0.05, FDR Method: BH). Other results of my analysis seem okay.

Is there a way to see exact results of both values? (like in SPSS) Unless there is an error, could you explain how these two values are calculated by this tool? Thank you!

[Yuxing Liao]

Zero means it is smaller than 2.220446e-16, the smallest positive floating-point number in R on the machine.

Yuxing

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