WImpiBLAST: Web Interface for mpiBLAST to Help Biologists Perform Large-Scale Annotation Using High Performance Computing

[Shrikant Mantri]

PLoS One. 2014 Jun 30;9(6):e101144. doi: 10.1371/journal.pone.0101144. eCollection 2014. http://dx.plos.org/10.1371/journal.pone.0101144

WImpiBLAST: Web Interface for mpiBLAST to Help Biologists Perform Large-Scale Annotation Using High Performance Computing.

http://dx.plos.org/10.1371/journal.pone.0101144

This paper presents the open-source WImpiBLAST web interface for mpiBLAST and discusses in detail the design decisions taken during its development, its robust architecture and use cases. The user-friendly WImpiBLAST interface will facilitate and encourage the use of supercomputing resources by biologists. This research will have a direct impact on the rate of knowledge discovery by accelerating various large-scale annotation projects.

Demonstration Server is accessible at : www.wimpiblast.nabi.res.in

Source Code: https://code.google.com/p/wimpiblast/

We strongly feel that the institutes having in-house HPC facility can port this WImpiBLAST software on their Cluster so that biologist/other researchers can have user-friendly access to supercomputing resource to submit annotation jobs and accelerate transcriptome, genome and metagenome annotation tasks.

The architecture adopted in this project (codebase)  can also be used as a template for porting any scientific computing application.

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Thanks and Regards,
Shrikant S. Mantri
Scientist (Computational Biology)
National Agri-Food Biotechnology Institute (NABI)
(Department of Biotechnology, Government of India)
C-127, Industrial Area, Phase VIII, S.A.S. Nagar, Mohali
Punjab, India-160071
TEL{Office}:+91(172)2290104 Fax: +91(172)4604888

Email: shri...@nabi.res.in, bioin...@gmail.com