Hi C. L. Martinez,
If these messages have appeared in your log file, one or more of your agent components are flooding the agent queue and it is not a normal behavior. If you want to find out what is causing that amount of events you could check what module (syscheck, OpenSCAP, etc...) have a big load of work or show us the configuration files if you prefer.
Those parameters for the agent queue configuration are limited due to OS limitations, so it is not possible to make them bigger. You also have the possibility to disable the queue with the "<disabled>" option. However, it exists the possibility of flooding the manager and lost events incoming from every agent.
I hope it helps.
Best regards,
Chema.