The rasters that are too large and caused me trouble are DEMs from The National Map USGS
https://viewer.nationalmap.gov/basic/
I stitched together elevation maps from lon/lat (-111, 43) to (-101, 36) and made a slope, aspect, and ruggedness layer (each around 43,000,000 KB). I expanded the pixel size to about 10 meters (ca. 3,000,000 KB each) and then followed the suggestion to round/make them integers and got to ca. 1,000,000 KB each and they are now working in VisTrails/sahm!
Let me know if you need any other information.