Does VTS have any DCS capabilities?

[Samantha Zerafa]

Hello!

I was wondering if the VTS (MCCL specifically) had any existing capabilities to simulate diffuse correlation spectroscopy (DCS). For example, is there a direct way to get G1 data (normalized autocorrelation/DCS data) or a way to post process the existing code for DCS to generate G1?

Thanks!

~Sam

[Carole Hayakawa]

Hi Sam,

Thanks for your question.  The MCCL has been used to determine G1 results, however additional processing not in MCCL is needed.  The following publications used the MCCL to determine G1:

1) Rice, T., E. Kwan, C.K. Hayakawa, A.J. Durkin, B. Choi and B.J. Tromberg.

``Quantitative, depth-resolved determination of particle motion using multi-exposure, spatial frequency domain laser speckle imaging.''

Biomedical Optics Express, 4(12), 2779-2892, 2013.

2) Regan, C., C.K. Hayakawa and B. Choi.
``Momentum transfer Monte Carlo for the simulation of laser speckle imaging and its application in the skin.''
Biomedical Optics Express, 8(12), 5708-5723, 2017.

In 1) for example, the estimate of P(Y,rho) is performed by the MCCL, however code to produce the estimate of G1 (Eq. 3 or 4) is not part of the code base.

Best,

Carole