Annotations on Structures topic (and also "Deep Homology", "Pangenome" and "Phylogeny")

[Jan T. Kim]

Hi All,

what is the state of the "Annotations on Structures" group?
Is there a specific forum (on Slack or wherever)?

I started a toy project mainly to get myself up to speed to
some extent, and ended up colouring amino acids in protein
structures according to degrees of diversity in the encoding
codons, see [1]. Having noticed the "Annotations on Structures"
topic this seems quite related?

Further topics that I think are related include "Pangenome"
and "Deep Homology" as potential sources for diversity data,
and also "Phylogeny". I'm also interested in epidemiological
modelling as well -- and in any thoughts you might have on
my toy project so far.

Best regards, Jan


[1] https://github.com/jttkim/covid19

[Pjotr Prins]

Hi Jan,

Why don't you start with coordinating the effort. Put your name on the
Wiki and tell people how to connect on Slack or something.

Pj.

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[Gerardo Tauriello]

Ciao Jan,

This is great. Thanks for posting this and my apologies for not having answered earlier.

Fortunately, I see that you already found the wiki page for the topic (https://github.com/virtual-biohackathons/covid-19-bh20/wiki/Annotations-on-Structures) and the slack channel (#annotations-on-structures).

The "toy project" you did is definitely a great start into this and goes exactly in the direction that we have in mind for that topic. I also agree that many other topics are connected in the sense that they can provide information that can be mapped on structures and that the structure-data can in turn inform those topics. Our github project (https://github.com/SWISS-MODEL/covid-19-Annotations-on-Structures) contains a couple of ideas for annotations including variations (similar to your toy project) and interactions with other topics in the hackathon.

Your help on this topic is greatly appreciated. Looking forward to interacting more with you in the next days (via Slack since I won't look here very often).

Regards,

Gerardo

[LJ.Garcia]

Hi there,

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