Background: COVID-19 has likely affected the delivery of interventions to prevent blood-borne viruses (BBVs) among people who inject drugs (PWID). We examined the impact of the first wave of COVID-19 in Scotland on: 1) needle and syringe provision (NSP), 2) opioid agonist therapy (OAT) and 3) BBV testing.
Conclusions: COVID-19 impacted the delivery of BBV prevention services for PWID in Scotland. While there is evidence of service recovery; further effort is likely required to return some intervention coverage to pre-pandemic levels in the context of subsequent waves of COVID-19.
Unlocking the First Wave of Breakthrough Steel Investments is the product of a series of forums convened by the ETC, with the support of Breakthrough Energy, to foster full-value chain dialogue in different steelmaking regions. Each regional insight report synthesises the analysis and debate to determine what it will take. The international report and infographic bring together and summarise the insights of the regional instalments.
Summary answer: Using datasets on live births per month in Europe, collected from the Human Fertility Database, we found a -14.1% decline in live births in January 2021 (i.e. 9-10 months after the epidemic peaks and first lockdowns), compared to the average number of live births in January 2018 and 2019.
What is known already: Previous pandemics in the 20th and 21st centuries have been associated with a decline in birth rates 9 months after their peak, and a rebound in births over time. Lockdowns were necessary to control the first wave of the COVID-19 pandemic and may have had an impact on subsequent birth rates.
Study design, size, duration: Monthly time series data on live births from January 2018 to March 2021 were extracted to provide a time-series analysis of birthrates during and after the first wave of the COVID-19 pandemic in 24 European countries.
Participants/materials, setting, methods: We conducted a random-effect generalized least squares regression to assess the seasonality of births from January 2018 to March 2021, and to identify potential differences in monthly live births after the first wave of the COVID-19 pandemic, considering the seasonality of births. To quantify these potential differences, we estimated the variation rate between the monthly live births observed during 2020 and 2021 and the mean of the 2018-2019 monthly live births in Europe. Factors potentially associated with a variation in monthly birth rates were assessed using univariable and multivariable generalized linear regressions.
Wider implications of the findings: As with previous pandemics, the COVID-19 outbreak was associated with a decline in births 9 months after its first wave. This trend may be associated with the duration of the lockdowns. Although there was a rebound in births in the following months, it does not seem to compensate for this decline.
Purpose: Our goal was to test transcutaneous focused ultrasound in the form of ultrasonic propulsion and burst wave lithotripsy to reposition ureteral stones and facilitate passage in awake subjects.
Materials and methods: Adult subjects with a diagnosed proximal or distal ureteral stone were prospectively recruited. Ultrasonic propulsion alone or with burst wave lithotripsy was administered by a handheld transducer to awake, unanesthetized subjects. Efficacy outcomes included stone motion, stone passage, and pain relief. Safety outcome was the reporting of associated anticipated or adverse events.
Results: Twenty-nine subjects received either ultrasonic propulsion alone (n = 16) or with burst wave lithotripsy bursts (n = 13), and stone motion was observed in 19 (66%). The stone passed in 18 (86%) of the 21 distal ureteral stone cases with at least 2 weeks follow-up in an average of 3.94.9 days post-procedure. Fragmentation was observed in 7 of the burst wave lithotripsy cases. All subjects tolerated the procedure with average pain scores (0-10) dropping from 2.12.3 to 1.62.0 (P = .03). Anticipated events were limited to hematuria on initial urination post-procedure and mild pain. In total, 7 subjects had associated discomfort with only 2.2% (18 of 820) propulsion bursts.
Conclusions: This study supports the efficacy and safety of using ultrasonic propulsion and burst wave lithotripsy in awake subjects to reposition and break ureteral stones to relieve pain and facilitate passage.
Born and raised in the Bronx, Dr. Nathalie Dougé is a New York-based, board-certified physician in internal medicine. A first-generation Haitian American, she is the first in her family to become a physician, receiving her medical degree from the Penn State College of Medicine. During the first wave of the COVID-19 pandemic in New York, she served as a hospitalist and assistant professor in the Department of Medicine at the Long Island Jewish Medical Center, an affiliate of Northwell Health. Nathalie currently lives in Queens, New York, and is a doting dog mom to her rescue, Mars, who she believes is one of her guardian angels in animal form.
Ahmed Ellis, a 36-year-old NYPD school safety officer and first-generation American, was born and raised in East Flatbush, Brooklyn, New York. He has been married to his wife, Alexis, for eight years and has two children, Austin (5) and Ava (2). The youngest of four, Ahmed spends much of his time with his tight-knit family, who originated from the small South American country of Guyana. Ahmed and Alexis,who works as a child life specialist within hospitals, were both considered essential workers and therefore continued to be called to work during the early days of the pandemic. After contracting COVID-19, Ahmed was hospitalized at Long Island Jewish Medical Center for two months.
Kellie Wunsch has been a registered nurse since 2009 and was part of the mobile critical care team at Long Island Jewish Medical Center. She grew up in Queens, New York, and later moved to Long Island, where she began working at LIJ and met her husband Tom. During the first wave of the pandemic, Kellie volunteered to be on the rapid response team that was dispatched throughout the hospital when patients became critically unstable. Like many healthcare workers, the pandemic took an emotional toll on Kellie. In the summer of 2020, she made the tough decision to turn in her scrubs and now works in the Bed Management Office at LIJ. Kellie cherishes every moment she gets with her husband and two young daughters. She is expecting her third child in November 2021.
760c119bf3