Depends. Probably, but...
The optimizing tiers are pretty good at inlining (it isn't called the
mother of all optimizations for nothing) but JIT compilers are, by
necessity, a bunch of heuristics and estimates, and they change all
the time. What works today need not work tomorrow.
In general, it's best to write your code in a straightforward manner
and not worry too much about performance upfront. V8 generally does a
lot better on mundane code than code that tries to be clever because
the former is its bread and butter. Only start thinking about tuning
when profiling shows hot spots.