Agreed - and to add to Phil L's advice, use gloves and googles [1] and put a
large dustsheet down to catch the broken shards, and empty this straight
into the wheelie bin when done.
As for preventing damage to the frame - almost impossible with hard putty
that's stuck well into the frame. When used to do the job, I simply took my
time and filled in any damage when applying and finishing the putty, and
then touched up the paintwork.
[1] I'm not a health and safety 'nut', but a splinter of glass in an eye
and cuts to the fingers are bloody painful - believe me!
Cash