Fwd: 10 international PhD positions in protein design for synthetic biology.

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daniel maeda

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Mar 9, 2019, 6:51:57 PM3/9/19
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From: <in...@drarbeit.de>
Date: Ijumaa, Feb 15, 2019 00:40
Subject: 10 international PhD positions in protein design for synthetic biology.
To: <SJD-B...@listserv.uni-heidelberg.de>


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Fachgebiete:     Biologie
Thema:           Doktorarbeit: 10 international PhD positions in protein design for synthetic biology.
Ansprechpartner: Dr. rer. nat. Eva Schlosser
Antwort an:      eva.sc...@helmholtz-muenchen.de
Institution:     Institut für Strukturbiologie
Ort:             85764  Neuherberg, Ingolstädter landstr. 1

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These positions are provided by RNAct, a European Innovative Training
Network project. The interdisciplinary research aim of RNAct is the design of novel RNA
recognition motif (RRM) proteins for exploitation in synthetic biology and bio-analytics. This
includes computational approaches at the sequence and structure levels of proteins and RNA, largescale
phage display experiments with RNA screening, integrative structural biology approaches,
implementation of RRMs in synthetic biology, and bio-analytics to detect RNA in-cell and design
RNA biochips.
ESR1: Predicting biophysical characteristics of proteins from their amino acid sequence
(Computational, VUB, Brussels, Belgium)
ESR2: Improving the in-silico structure representation of proteins (Computational, VUB, Brussels,
Belgium)
ESR3: Collect, integrate and analyse RRM data (Computational, CNRS, Nancy, France)
ESR4: Improve methods to dock RNA with proteins (Computational, CNRS, Nancy, France)
ESR5: Structure calculation and computational design of RRMs (Computational/Experimental,
HMGU, Munich, Germany)
ESR6: Structural biology (NMR, X-ray crystallography) and biophysical techniques of designed
RRMs (Experimental, HMGU, Munich, Germany)
ESR7: Analyse RRM dynamics via structural biology (NMR) and biophysical techniques
(Experimental, Giotto Biotech, Florence, Italy)
ESR8: Integrate RRMs in prokaryotes to create new pathways in synthetic biology (Experimental,
CSIC, Valencia, Spain)
ESR9: Create biochips to study RRM/RNA interactions. (Experimental, Dynamic Biosensors,
Munich, Germany)
ESR10: Deploy RRMs for in-cell analytics (Experimental, Ridgeview Instruments, Uppsala, Sweden)

Methoden:
RNAct is a collaborative project between 7 teams in 6 countries, from both academia and biotech
industry, that will offer a comprehensive and cross-disciplinary structured curriculum for doctoral
students. 10 doctoral thesis fellowships (for ESRs, Early-Stage Researchers) are available in the
areas of structural bioinformatics, structural biology using NMR and crystallography, synthetic
biology and bio-analytics.

Anfangsdatum: 1. Juli 2019

geschätzte Dauer: 3 Jahre (36 Monate)

Bezahlung: Europäische Gehälter für Early Stage Researcher

Homepage: http://rnact.eu

Eligible applicants must hold a Masters degree of Science (MSc) in the field of chemistry,
biochemistry, physical, life sciences or computational sciences as requested in the respective job
description. They must not have stayed in the country of the host lab for more than 1 year during the
last 3 years, and be in the first four years (full-time equivalent) of their research careers. Do not
apply if you already hold a Ph.D.
Further information:
Applications must be submitted online at
https://tinyurl.com/rnact-eu
Deadline for applications: 15/03/2019

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