Kaplan Meier for New Gene Set

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Ashlyn Michelle

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Mar 26, 2026, 5:43:17 PM (10 days ago) Mar 26
to UCSC Xena and Cancer Genomics Browser
I was wondering if it is possible to visualize Kaplan Meier plots fot a custom gene set/signature. I have 5 genes of interest within a pathway and am trying to combine their high/low expression data to see if the group is correlated with less survival. 

I can make a column for each individual gene and see the KM plot, but when I list all of the genes, separated with a comma, the KM plot is greyed out. Any adivce?

Mary Goldman

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Mar 28, 2026, 12:31:11 PM (8 days ago) Mar 28
to Ashlyn Michelle, UCSC Xena and Cancer Genomics Browser
Hi Ashlyn,

I recommend creating a signature for your set of genes (https://ucsc-xena.gitbook.io/project/overview-of-features/genomic-signatures) and then running the Kaplan Meier plot on that column. 

Let me know if you have any questions.

Best,
Mary
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Mary Goldman (she/her), Design and Outreach Engineer 

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On Thu, Mar 26, 2026 at 2:43 PM Ashlyn Michelle <a.m.ba...@gmail.com> wrote:
I was wondering if it is possible to visualize Kaplan Meier plots fot a custom gene set/signature. I have 5 genes of interest within a pathway and am trying to combine their high/low expression data to see if the group is correlated with less survival. 

I can make a column for each individual gene and see the KM plot, but when I list all of the genes, separated with a comma, the KM plot is greyed out. Any adivce?

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