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Type-1 Diabetes Clinical Trials News
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joshua levy
Jan 7
Rituximab and Treg Cells Starts a Phase IIΔ Trial In Youth At Risk Of Diabetes
A new clinical trial is exploring whether two different immune therapies, used alone or in
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Rituximab and Treg Cells Starts a Phase IIΔ Trial In Youth At Risk Of Diabetes
A new clinical trial is exploring whether two different immune therapies, used alone or in
Jan 7
joshua levy
12/17/25
Fecal Transplantation Starts A Phase-II Trial (FACT-T1D)
The Fecal Autologous Capsule Transplantation for Type 1 Diabetes Mellitus (FACT-T1D) trial is testing
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Fecal Transplantation Starts A Phase-II Trial (FACT-T1D)
The Fecal Autologous Capsule Transplantation for Type 1 Diabetes Mellitus (FACT-T1D) trial is testing
12/17/25
joshua levy
12/5/25
CNK-UT009 Cell Therapy Starts A Phase-I Clinical Trial
CNK-UT009, as tested here, is a one-time infusion of living cells designed to modify the immune
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CNK-UT009 Cell Therapy Starts A Phase-I Clinical Trial
CNK-UT009, as tested here, is a one-time infusion of living cells designed to modify the immune
12/5/25
joshua levy
10/29/25
IMMUNOSTEM starts a Phase-I Clinical Trial in Honeymooners
IMMUNOSTEM technology refers to using a virus (specifically a lentivirus) to deliver a new gene into
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IMMUNOSTEM starts a Phase-I Clinical Trial in Honeymooners
IMMUNOSTEM technology refers to using a virus (specifically a lentivirus) to deliver a new gene into
10/29/25
joshua levy
9/27/25
Results from a Phase-II Clinical Trial of Baricitinib
Baricitinib works by interfering with signaling pathways inside immune cells, to reduce inflammation
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Results from a Phase-II Clinical Trial of Baricitinib
Baricitinib works by interfering with signaling pathways inside immune cells, to reduce inflammation
9/27/25
joshua levy
9/6/25
Avotres Announces Results from a Phase-I Trial of AVT001
This blog posting reports on the results of Avotres recent phase-I clinical trial into AVT001 and the
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Avotres Announces Results from a Phase-I Trial of AVT001
This blog posting reports on the results of Avotres recent phase-I clinical trial into AVT001 and the
9/6/25
joshua levy
5/16/25
Diamyd’s GABA-Based Remygen® Unsuccessful in Phase 1 Clinical Trial
This clinical trial tested whether long-term daily treatment with Remygen®, an oral drug developed by
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Diamyd’s GABA-Based Remygen® Unsuccessful in Phase 1 Clinical Trial
This clinical trial tested whether long-term daily treatment with Remygen®, an oral drug developed by
5/16/25
joshua levy
5/8/25
Changes to My Blogging: AI
I'm going to start using generative AI (what people call "chatbot" technology) to help
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Changes to My Blogging: AI
I'm going to start using generative AI (what people call "chatbot" technology) to help
5/8/25
joshua levy
4/25/25
Sana Biotechnology Reports First Results For Islet Transplants Without Immunosuppression
This blog post reports on some news that I consider exciting, for at least two different reasons:
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Sana Biotechnology Reports First Results For Islet Transplants Without Immunosuppression
This blog post reports on some news that I consider exciting, for at least two different reasons:
4/25/25
joshua levy
3/18/25
TIXIMED Starts a Phase 1 Study of TIX100
TIX100 is a protein which inhibits the action of TIXNP (thioredoxin-interacting protein). It is being
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TIXIMED Starts a Phase 1 Study of TIX100
TIX100 is a protein which inhibits the action of TIXNP (thioredoxin-interacting protein). It is being
3/18/25
joshua levy
3/7/25
Combination of Harmine and GLP-1RA Completes Phase-I Clinical Trial (In Healthy People)
This is the most fun I have had writing a blog in a long time. It is not often I can blog about
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Combination of Harmine and GLP-1RA Completes Phase-I Clinical Trial (In Healthy People)
This is the most fun I have had writing a blog in a long time. It is not often I can blog about
3/7/25
joshua levy
1/31/25
Denosumab Starts A Phase-I Trial In People With Established T1D
Denosumab is a monoclonal antibody, which is already approved for several bone related diseases and
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Denosumab Starts A Phase-I Trial In People With Established T1D
Denosumab is a monoclonal antibody, which is already approved for several bone related diseases and
1/31/25
joshua levy
1/19/25
What To Watch In 2025
Last year, at the start of the year, I published a blog of four research projects I was looking
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What To Watch In 2025
Last year, at the start of the year, I published a blog of four research projects I was looking
1/19/25
joshua levy
12/31/24
JDRF Funding for a Cure 2024
Normally, sometime in October, I write a summary of all the clinical trials funded by JDRF. However,
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JDRF Funding for a Cure 2024
Normally, sometime in October, I write a summary of all the clinical trials funded by JDRF. However,
12/31/24
joshua levy
12/23/24
Fenofibrate Is Unsuccessful In A Phase-IIΔ Trial In Honeymooners
Fenofibrate (also spelled Phenofibrate) is commonly prescribed for high cholesterol and high
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Fenofibrate Is Unsuccessful In A Phase-IIΔ Trial In Honeymooners
Fenofibrate (also spelled Phenofibrate) is commonly prescribed for high cholesterol and high
12/23/24
joshua levy
11/19/24
Encellin Starts a Phase-I Trial of ENC-201-CED (Encapsulated Beta Cells)
The company Encellin has started a Phase-I clinical trial to test ENC-201-CED an encapsulated beta
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Encellin Starts a Phase-I Trial of ENC-201-CED (Encapsulated Beta Cells)
The company Encellin has started a Phase-I clinical trial to test ENC-201-CED an encapsulated beta
11/19/24
joshua levy
11/8/24
Frexalimab Starts A Phase-IIΔ Clinical Trial (FABULINUS)
There are two good reasons to test Frexalimab as a cure or treatment for Type-1 Diabetes (T1D). The
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Frexalimab Starts A Phase-IIΔ Clinical Trial (FABULINUS)
There are two good reasons to test Frexalimab as a cure or treatment for Type-1 Diabetes (T1D). The
11/8/24
joshua levy
10/6/24
The full story on "Stem cells reverse woman’s diabetes — a world first"
If you've been reading news recently you might have seen headlines like these: Stem cells reverse
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The full story on "Stem cells reverse woman’s diabetes — a world first"
If you've been reading news recently you might have seen headlines like these: Stem cells reverse
10/6/24
joshua levy
8/18/24
Combo of Rituximab and Abatacept Starts a Phase-II In Honeymooners (T1D RELAY)
Rituximab is FDA-approved to treat several autoimmune diseases, including Rheumatoid Arthritis (RA).
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Combo of Rituximab and Abatacept Starts a Phase-II In Honeymooners (T1D RELAY)
Rituximab is FDA-approved to treat several autoimmune diseases, including Rheumatoid Arthritis (RA).
8/18/24
joshua levy
7/16/24
Abrocitinib and Ritlecitinib Start A Phase-IIΔ Clinical Trail in Honeymooners (JAKPOT)
(Note: JAKPOT is a name of at least two different clinical trials. If you are reading about a French
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Abrocitinib and Ritlecitinib Start A Phase-IIΔ Clinical Trail in Honeymooners (JAKPOT)
(Note: JAKPOT is a name of at least two different clinical trials. If you are reading about a French
7/16/24
joshua levy
6/4/24
BMF-219 Starts a Phase-IIΔ
BMF-219 is a drug that inhibits Menin, a protein. Menin's functions in cells are not fully
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BMF-219 Starts a Phase-IIΔ
BMF-219 is a drug that inhibits Menin, a protein. Menin's functions in cells are not fully
6/4/24
joshua levy
5/1/24
Fenofibrate Starts A Phase-IIΔ Trial
Fenofibrate (also spelled Phenofibrate) is commonly prescribed for high cholesterol and high
unread,
Fenofibrate Starts A Phase-IIΔ Trial
Fenofibrate (also spelled Phenofibrate) is commonly prescribed for high cholesterol and high
5/1/24
joshua levy
4/26/24
Siplizumab Starts Two Trials in Honeymoon T1D (DESIGNATE and STRIDE)
Siplizumab (MEDI-507, TCD601) is an monoclonal antibody which targets CD2 cells in the immune system.
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Siplizumab Starts Two Trials in Honeymoon T1D (DESIGNATE and STRIDE)
Siplizumab (MEDI-507, TCD601) is an monoclonal antibody which targets CD2 cells in the immune system.
4/26/24
joshua levy
4/12/24
Why I Don't Blog On How To Vote For T1D (part 1)
This whole blog posting is very US (and US politics) focused, but the issues are similar in other
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Why I Don't Blog On How To Vote For T1D (part 1)
This whole blog posting is very US (and US politics) focused, but the issues are similar in other
4/12/24
joshua levy
3/22/24
New Blog: Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People
Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People My previous blog posting:
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New Blog: Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People
Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People My previous blog posting:
3/22/24
joshua levy
3/8/24
Levicure's Combination Therapy
Levicure is a startup which is currently raising money to fund a phase-II trial for a combination
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Levicure's Combination Therapy
Levicure is a startup which is currently raising money to fund a phase-II trial for a combination
3/8/24
joshua levy
1/30/24
Results from a Phase-IIΔ Trial of Pleconaril and Ribavirin
This clinical trial represents an attack on T1D slightly different than anything I've blogged on
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Results from a Phase-IIΔ Trial of Pleconaril and Ribavirin
This clinical trial represents an attack on T1D slightly different than anything I've blogged on
1/30/24
joshua levy
1/22/24
Results From A Phase-IIΔ Baricitinib (Olumiant)
Baricitinib (trade name Olumiant) is a drug which targets the immune system, and is already approved
unread,
Results From A Phase-IIΔ Baricitinib (Olumiant)
Baricitinib (trade name Olumiant) is a drug which targets the immune system, and is already approved
1/22/24
joshua levy
1/6/24
What To Watch In 2024
At the start of a new year, some bloggers write a posting on the year that was, and a some write a
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What To Watch In 2024
At the start of a new year, some bloggers write a posting on the year that was, and a some write a
1/6/24
joshua levy
12/24/23
Diamyd Update
This is my first update on the Diamyd company in many, many years. It is focused on their DIAGNODE-3
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Diamyd Update
This is my first update on the Diamyd company in many, many years. It is focused on their DIAGNODE-3
12/24/23