Type-1 Diabetes Clinical Trials News

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Aug 18

Combo of Rituximab and Abatacept Starts a Phase-II In Honeymooners (T1D RELAY)

Rituximab is FDA-approved to treat several autoimmune diseases, including Rheumatoid Arthritis (RA).

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Combo of Rituximab and Abatacept Starts a Phase-II In Honeymooners (T1D RELAY)

Rituximab is FDA-approved to treat several autoimmune diseases, including Rheumatoid Arthritis (RA).

Aug 18

Jul 16

Abrocitinib and Ritlecitinib Start A Phase-IIΔ Clinical Trail in Honeymooners (JAKPOT)

(Note: JAKPOT is a name of at least two different clinical trials. If you are reading about a French

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Abrocitinib and Ritlecitinib Start A Phase-IIΔ Clinical Trail in Honeymooners (JAKPOT)

(Note: JAKPOT is a name of at least two different clinical trials. If you are reading about a French

Jul 16

Jun 4

BMF-219 Starts a Phase-IIΔ

BMF-219 is a drug that inhibits Menin, a protein. Menin's functions in cells are not fully

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BMF-219 Starts a Phase-IIΔ

BMF-219 is a drug that inhibits Menin, a protein. Menin's functions in cells are not fully

Jun 4

May 1

Fenofibrate Starts A Phase-IIΔ Trial

Fenofibrate (also spelled Phenofibrate) is commonly prescribed for high cholesterol and high

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Fenofibrate Starts A Phase-IIΔ Trial

Fenofibrate (also spelled Phenofibrate) is commonly prescribed for high cholesterol and high

May 1

Apr 26

Siplizumab Starts Two Trials in Honeymoon T1D (DESIGNATE and STRIDE)

Siplizumab (MEDI-507, TCD601) is an monoclonal antibody which targets CD2 cells in the immune system.

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Siplizumab Starts Two Trials in Honeymoon T1D (DESIGNATE and STRIDE)

Siplizumab (MEDI-507, TCD601) is an monoclonal antibody which targets CD2 cells in the immune system.

Apr 26

Apr 12

Why I Don't Blog On How To Vote For T1D (part 1)

This whole blog posting is very US (and US politics) focused, but the issues are similar in other

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Why I Don't Blog On How To Vote For T1D (part 1)

This whole blog posting is very US (and US politics) focused, but the issues are similar in other

Apr 12

Mar 22

New Blog: Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People

Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People My previous blog posting:

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New Blog: Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People

Diamyd Update Part 2: JDRF Flexibilty In Funding and Diamyd In More People My previous blog posting:

Mar 22

Mar 8

Levicure's Combination Therapy

Levicure is a startup which is currently raising money to fund a phase-II trial for a combination

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Levicure's Combination Therapy

Levicure is a startup which is currently raising money to fund a phase-II trial for a combination

Mar 8

Jan 30

Results from a Phase-IIΔ Trial of Pleconaril and Ribavirin

This clinical trial represents an attack on T1D slightly different than anything I've blogged on

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Results from a Phase-IIΔ Trial of Pleconaril and Ribavirin

This clinical trial represents an attack on T1D slightly different than anything I've blogged on

Jan 30

Jan 22

Results From A Phase-IIΔ Baricitinib (Olumiant)

Baricitinib (trade name Olumiant) is a drug which targets the immune system, and is already approved

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Results From A Phase-IIΔ Baricitinib (Olumiant)

Baricitinib (trade name Olumiant) is a drug which targets the immune system, and is already approved

Jan 22

Jan 6

What To Watch In 2024

At the start of a new year, some bloggers write a posting on the year that was, and a some write a

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What To Watch In 2024

At the start of a new year, some bloggers write a posting on the year that was, and a some write a

Jan 6

12/24/23

This is my first update on the Diamyd company in many, many years. It is focused on their DIAGNODE-3

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This is my first update on the Diamyd company in many, many years. It is focused on their DIAGNODE-3

12/24/23

12/16/23

Islet Cell Transplantation Clinical Trails

In this blog I'm going to report on three different clinical trials involving transplantation.

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Islet Cell Transplantation Clinical Trails

In this blog I'm going to report on three different clinical trials involving transplantation.

12/16/23

11/28/23

Teplizumab/Tzield Reports Results From A Phase-III in Honeymooners (PROTECT)

Teplizumab (sold as Tzield) was recently approved for use in people at-risk of diagnosis for T1D. At

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Teplizumab/Tzield Reports Results From A Phase-III in Honeymooners (PROTECT)

Teplizumab (sold as Tzield) was recently approved for use in people at-risk of diagnosis for T1D. At

11/28/23

11/11/23

JDRF Funding for a Cure 2023

In the US, we are in the "Walking Season" when JDRF (Juvenile Diabetes Research Foundation)

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JDRF Funding for a Cure 2023

In the US, we are in the "Walking Season" when JDRF (Juvenile Diabetes Research Foundation)

11/11/23

10/9/23

DFMO Starts A Phase-II Clinical Trial (TADPOL)

Difluoromethylornithine (DFMO), also known as Eflornithine, is FDA approved since 1990 as an

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DFMO Starts A Phase-II Clinical Trial (TADPOL)

Difluoromethylornithine (DFMO), also known as Eflornithine, is FDA approved since 1990 as an

10/9/23

9/21/23

Strong Results from a Pilot Study of Semaglutide in Adult Honeymooners

I've been blogging on research aimed at curing type-1 diabetes for over 15 years, and in that

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Strong Results from a Pilot Study of Semaglutide in Adult Honeymooners

I've been blogging on research aimed at curing type-1 diabetes for over 15 years, and in that

9/21/23

7/31/23

T1D Research News (Quick Bits for July)

This blog is a collection of smaller news items about T1D. COVID Not Likely to Increase T1D in

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T1D Research News (Quick Bits for July)

This blog is a collection of smaller news items about T1D. COVID Not Likely to Increase T1D in

7/31/23

6/12/23

CELZ-201 Starts a Phase-I Trial (CREATE-1)

CELZ-201 is a stem cell product, where the cells are isolated from the umbilical cord, Wharton's

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CELZ-201 Starts a Phase-I Trial (CREATE-1)

CELZ-201 is a stem cell product, where the cells are isolated from the umbilical cord, Wharton's

6/12/23

5/9/23

Dompé Starts GLADIATOR, a Phase-III Clinical Trial of Ladarixin

Ladarixin is a drug being develop by Dompé (an Italian company). It inhibits activity on parts of the

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Dompé Starts GLADIATOR, a Phase-III Clinical Trial of Ladarixin

Ladarixin is a drug being develop by Dompé (an Italian company). It inhibits activity on parts of the

5/9/23

4/7/23

T1D Research News (Quick Bits from April)

This blog covers three pieces of news which do not apply directly to cure focused research, but which

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T1D Research News (Quick Bits from April)

This blog covers three pieces of news which do not apply directly to cure focused research, but which

4/7/23

3/31/23

Results from a Phase-II Verapamil Study

Verapamil is a drug which has been used in the US since 1982 for high blood pressure, migraines, and

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Results from a Phase-II Verapamil Study

Verapamil is a drug which has been used in the US since 1982 for high blood pressure, migraines, and

3/31/23

3/20/23

Influenza Vaccination Starts a Phase-II? Clinical Trial

This is a straight forward clinical trial: people recently diagnosed with type 1 diabetes (in their

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Influenza Vaccination Starts a Phase-II? Clinical Trial

This is a straight forward clinical trial: people recently diagnosed with type 1 diabetes (in their

3/20/23

2/27/23

Ixekizumab (Taltz) Starts a Phase-II? Trial In Honeymooners

Ixekizumab, sold under the trade name Taltz, blocks a specific part of the immune system called

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Ixekizumab (Taltz) Starts a Phase-II? Trial In Honeymooners

Ixekizumab, sold under the trade name Taltz, blocks a specific part of the immune system called

2/27/23

2/9/23

OPT101 Starts A Phase-I Trial in Adults with Established T1D

OPT101 is a peptide derived from mouse CD154. What does that mean? A peptide is a small part of a

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OPT101 Starts A Phase-I Trial in Adults with Established T1D

OPT101 is a peptide derived from mouse CD154. What does that mean? A peptide is a small part of a

2/9/23

12/26/22

Youtube Video Describing How JDRF Makes Funding Decisions

If you care about research aimed at curing type-1 diabetes, then you should care about JDRF's

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Youtube Video Describing How JDRF Makes Funding Decisions

If you care about research aimed at curing type-1 diabetes, then you should care about JDRF's

12/26/22

12/16/22

ASDCC Starts Phase-I Clinical Trial of Extracorporeal Photopheresis (Opera)

This is a phase-I, 10 person trial which started in September 2022, and is expected to finish in

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ASDCC Starts Phase-I Clinical Trial of Extracorporeal Photopheresis (Opera)

This is a phase-I, 10 person trial which started in September 2022, and is expected to finish in

12/16/22

12/3/22

The FDA Approves Teplizumab Under The Name TZIELD™ (teplizumab-mzwv)

On 17-Nov-2022, The USA FDA approved Teplizumab. This is the first drug ever approved in the United

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The FDA Approves Teplizumab Under The Name TZIELD™ (teplizumab-mzwv)

On 17-Nov-2022, The USA FDA approved Teplizumab. This is the first drug ever approved in the United

12/3/22

11/16/22

Results from MultiPepT1De (Multi Peptide Vaccine) by Powrie at King’s College London

This is the most recent result from a long line of research led by Colin Dayan and Mark Peakman, at

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Results from MultiPepT1De (Multi Peptide Vaccine) by Powrie at King’s College London

This is the most recent result from a long line of research led by Colin Dayan and Mark Peakman, at

11/16/22

10/16/22

JDRF Funding for a Cure 2022

In the US, we are in the "Walking Season" when JDRF (Juvenile Diabetes Research Foundation)

unread,

JDRF Funding for a Cure 2022

In the US, we are in the "Walking Season" when JDRF (Juvenile Diabetes Research Foundation)

10/16/22

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