Question on Hypothalamic Representation in TVB Connectomes

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Ogonnaya Uma

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Jan 2, 2026, 1:59:56 AMJan 2

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Hello everyone, and happy new year.

My team seeks to use The Virtual Brain to model experiential states as network-level synchrony, examine their robustness under noise, and test whether such states can reliably engage subcortical regulatory nodes within a biologically plausible connectome.

I’m currently running into a limitation regarding hypothalamic representation. I’ve gone through prior forum discussions and datasets but haven’t found a TVB-compatible connectome that includes hypothalamic nuclei with an appropriate connectivity matrix. If such a resource exists, I’d be grateful for pointers. Otherwise, I’d appreciate suggestions on best-practice alternatives for modeling hypothalamic involvement within TVB.