Simulating Epileptic Brain

[Tristan Delion]

Hi TVB community,

I am a final year MSc student in neuroscience, with a background in biology (but not in mathematics or engineering).

This year, we have a computational neuroscience module. As part of the assessment, we have to write a 10 pages report on simulating an epileptic brain. Our teacher is giving us this work, and the only support he gave us is the TVB tutorial video.

However, I have no experience in coding and  I've never encountered jupyter notebook and python before. At the moment, I just feel lost, and do not know where to start.

I would be very grateful if anyone could direct me towards resources and a starting point in order to understand the simulation of an epileptic brain.

Warm wishes,

Tristan

[Julie Courtiol]

Dear Tristan,

I advise you to read the following papers:

• Jirsa et al., Neuron, 2014: https://doi.org/10.1093/brain/awu133
• Proix et al., J Neurosci, 2014: https://doi.org/10.1523/JNEUROSCI.1570-14.2014
• Jirsa et al., Neuroimage, 2016: https://doi.org/10.1016/j.neuroimage.2016.04.049
• Hashemi et al., Neuroimage, 2020: https://doi.org/10.1016/j.neuroimage.2020.116839

If you are not familiar with large-scale brain network modeling, I recommend to read:

• Sanz-Leon et al., Neuroimage, 2015: https://doi.org/10.1016/j.neuroimage.2015.01.002

There are also some lectures that I have done, e.g.: https://www.youtube.com/watch?v=N04jnFB3QbA

And TVB tutorials, either with the GUI or the python notebook: 

https://github.com/the-virtual-brain/tvb-root/blob/master/tvb_documentation/tutorials/tutorial_3_ModelingEpilepsy.rst

https://github.com/the-virtual-brain/tvb-root/blob/master/tvb_documentation/tutorials/tutorial_s6_ModelingEpilepsy.ipynb

Best,

Julie

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Best regards,

Dr. Julie Courtiol

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