It’s difficult to know with certainty without the diagnostic information that we request you post along with your problem. But my guess is that your configuration requires the use of an earlier version of OpenSSL or OpenVPN or both. Newer versions of Tunnelblick default to using newer versions of openVPN/OpenSSL, but you can choose an earlier version in the settings.
See Tunnelblick 4, which also applies to newer versions of Tunnelblick such as Tunnelblick 6 and 8, which also use even newer versions of OpenVPN/OpenSSL.)