infercnv workflow won't start

[Beatrice Awasthi]

Hello,

I am new to running infercnv and trying to run it on a dataset of 100,000 cells and 40,000 genes. I have been trying to submit a workflow on Terra, but it consistently fails; from what I can tell, the job won't even start because it can't access my data. I am able to run it in Rstudio using the same inputs, so I think the inputs are fine. The issue in Rstudio is that it keeps crashing due to memory/storage (I haven't made it past step 18), and I'm not able to do anything else in the meantime, so I am hoping to get the workflows to work. In the meantime, I am just running it sample by sample, but that is quite inefficient, and it hasn't worked yet. Would you have any insights into what the problem could be?

Thank you so much!