Announcement: CTAT-Mutations v4.2.0 available

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Jun 3, 2024, 4:14:56 PM6/3/24

to Trinity_CTAT_users

Greetings all,

A new version of CTAT-Mutations is now available:

Release notes:

for faster workflow, set default boosting to 'none' and turned off blat_ED and annot pass annotations unless boosting is indicated.
ctat mutation wdl and Terra wrapper wdls updated
added bamsifter and strand-specific read normalization
replace gatk cigar-N-splitter with our own pysam based version
add ctat-mutations to dockstore for easy integration into terra or other supported cloud platforms

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Jun 29, 2024, 7:22:35 PM6/29/24

to Trinity_CTAT_users

Please note, for long-read calling, the CTAT-Mutations v4.2.0 - while still performing well - was not reaching its maximum potential.

We have a new release v4.3.0 that includes an important update relevant to long read RNA-seq variant calling. Please upgrade asap if relevant:

https://github.com/TrinityCTAT/ctat-mutations/releases/tag/CTAT-Mutations-v4.3.0

CTAT-Mutations Release v4.3.0 Latest

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brianjohnhaas released this 7 minutes ago

4.3.0 June 29, 2024

bugfix w/ cigar-N-splitter, incorporating the required read group ID in each alignment entry - impacts long read calling sensitivity

for faster workflow, set default boosting to 'none' and turned off blat_ED and annot pass annotations unless boosting is indicated.
ctat mutation wdl and Terra wrapper wdls updated
added bamsifter and strand-specific read normalization
replace gatk cigar-N-splitter with our own pysam based version
add ctat-mutations to dockstore for easy integration into terra or other supported cloud platforms

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