Thank you for all your responses.
Although I am interested in these examples I think my question is really better phrased as the following:
Can TiddlyWiki (potentially) connect to a REST API?
I ask because TiddlyWiki is obviously a fairly unusual program, so I wasn't sure if there was some reason that this would not be possible. I accept that this is likely a very noobish question - I currently know next to nothing about TiddlyWiki or RESTful interfaces.
Again I am not really looking for solutions at the moment, just a sense of what may be possible for me to mess around with down the line.